메뉴 건너뛰기




Volumn , Issue , 2015, Pages 335-369

Animal models of cardiovascular diseaseines

Author keywords

Animal Models; Cardiovascular Disease; Heart Failure; Metabolic Syndrome; Rodents

Indexed keywords


EID: 84944544778     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-319-08798-6_19     Document Type: Chapter
Times cited : (3)

References (188)
  • 1
    • 84864477617 scopus 로고    scopus 로고
    • Esc guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the european society of cardiology. developed in collaboration with the heart failure association (hfa) of the esc
    • McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2012;14:803-69.
    • (2012) Eur J Heart Fail , vol.14 , pp. 803-869
    • McMurray, J.J.1    Adamopoulos, S.2    Anker, S.D.3    Auricchio, A.4    Bohm, M.5    Dickstein, K.6
  • 2
    • 33646231760 scopus 로고    scopus 로고
    • Current perspectives in diastolic dysfunction and diastolic heart failure
    • Leite-Moreira AF. Current perspectives in diastolic dysfunction and diastolic heart failure. Heart. 2006;92:712-8.
    • (2006) Heart , vol.92 , pp. 712-718
    • Leite-Moreira, A.F.1
  • 3
    • 33751067468 scopus 로고    scopus 로고
    • Small animal models of cardiovascular disease: Tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis
    • Russell JC, Proctor SD. Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis. Cardiovasc Pathol. 2006;15:318-30.
    • (2006) Cardiovasc Pathol , vol.15 , pp. 318-330
    • Russell, J.C.1    Proctor, S.D.2
  • 4
    • 77957216320 scopus 로고
    • Fatty, a new mutation in the rat
    • Zucker LM, Zucker TF. Fatty, a new mutation in the rat. J Hered. 1961;52:275-8.
    • (1961) J Hered , vol.52 , pp. 275-278
    • Zucker, L.M.1    Zucker, T.F.2
  • 5
    • 0001717747 scopus 로고
    • Shhf/mcc-cp rat: Model of obesity, non-insulin-dependent diabetes, and congestive heart failure
    • McCune S, Baker P, Stills H. SHHF/Mcc-cp rat: model of obesity, non-insulin-dependent diabetes, and congestive heart failure. ILAR J. 1990;32(3): 23-7.
    • (1990) ILAR J , vol.32 , Issue.3 , pp. 23-27
    • McCune, S.1    Baker, P.2    Stills, H.3
  • 6
    • 0014540971 scopus 로고
    • Streptozotocin- and alloxan- diabetes in mice
    • Rerup C, Tarding F. Streptozotocin- and alloxan- diabetes in mice. Eur J Pharmacol. 1969;7:89-96.
    • (1969) Eur J Pharmacol , vol.7 , pp. 89-96
    • Rerup, C.1    Tarding, F.2
  • 7
    • 38949135755 scopus 로고    scopus 로고
    • Molecular mechanisms for myocardial mitochondrial dysfunction in the meta-bolic syndrome
    • Bugger H, Abel ED. Molecular mechanisms for myocardial mitochondrial dysfunction in the meta-bolic syndrome. Clin Sci (Lond). 2008;114: 195-210.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 195-210
    • Bugger, H.1    Abel, E.D.2
  • 8
    • 33751217697 scopus 로고    scopus 로고
    • Diabetic mice exhibit contractile dysfunction but maintain cardiac output by favourable loading conditions
    • Van den Bergh A, Flameng W, Herijgers P. Type II diabetic mice exhibit contractile dysfunction but maintain cardiac output by favourable loading conditions. Eur J Heart Fail. 2006;8:777-83.
    • (2006) Eur J Heart Fail , vol.8 , pp. 777-783
    • Van Den Bergh, A.1    Flameng, W.2    Herijgers, P.3    Type, I.I.4
  • 9
    • 33644813721 scopus 로고    scopus 로고
    • Myocardial infarction and heart failure in the db/db diabetic mouse
    • Greer JJ, Ware DP, Lefer DJ. Myocardial infarction and heart failure in the db/db diabetic mouse. Am J Physiol Heart Circ Physiol. 2006;290:H146-H153.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H146-H153
    • Greer, J.J.1    Ware, D.P.2    Lefer, D.J.3
  • 10
    • 34347352169 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy revisited
    • Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007;115:3213-23.
    • (2007) Circulation , vol.115 , pp. 3213-3223
    • Boudina, S.1    Abel, E.D.2
  • 11
    • 0028345073 scopus 로고
    • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor- negative mice
    • Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor- negative mice. J Clin Invest. 1994;93:1885-93.
    • (1994) J Clin Invest , vol.93 , pp. 1885-1893
    • Ishibashi, S.1    Goldstein, J.L.2    Brown, M.S.3    Herz, J.4    Burns, D.K.5
  • 12
    • 0028926809 scopus 로고
    • The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure
    • Bing OH, Brooks WW, Robinson KG, Slawsky MT, Hayes JA, Litwin SE, et al. The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure. J Mol Cell Cardiol. 1995;27:383-96.
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 383-396
    • Bing, O.H.1    Brooks, W.W.2    Robinson, K.G.3    Slawsky, M.T.4    Hayes, J.A.5    Litwin, S.E.6
  • 13
    • 77953656472 scopus 로고    scopus 로고
    • Small animal models of heart failure: Development of novel therapies, past and present
    • Patten RD, Hall-Porter MR. Small animal models of heart failure: development of novel therapies, past and present. Circ Heart Fail. 2009;2:138-44.
    • (2009) Circ Heart Fail , vol.2 , pp. 138-144
    • Patten, R.D.1    Hall-Porter, M.R.2
  • 14
    • 0030962709 scopus 로고    scopus 로고
    • The transition to failure in the spontaneously hypertensive rat
    • Mitchell GF, Pfeffer JM, Pfeffer MA. The transition to failure in the spontaneously hypertensive rat. Am J Hypertens. 1997;10:120S-6.
    • (1997) Am J Hypertens , vol.10 , pp. 120S-6S
    • Mitchell, G.F.1    Pfeffer, J.M.2    Pfeffer, M.A.3
  • 17
    • 19744372532 scopus 로고    scopus 로고
    • Male gender and not the severity of hypertension is associated with end-organ
    • Masineni S, Chander P, Singh G, Powers C, Stier CJ. Male gender and not the severity of hypertension is associated with end-organ. Am J Hypertens. 2005;18:878-84.
    • (2005) Am J Hypertens , vol.18 , pp. 878-884
    • Masineni, S.1    Chander, P.2    Singh, G.3    Powers, C.4    Stier, C.J.5
  • 18
    • 0037305207 scopus 로고    scopus 로고
    • Calcium-dependent arrhythmias in transgenic mice with heart failure
    • London B, et al. Calcium-dependent arrhythmias in transgenic mice with heart failure. Am J Physiol Heart Circ Physiol. 2003;284(2):H431-41.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , Issue.2 , pp. H431-HH41
    • London, B.1
  • 20
    • 1842294625 scopus 로고    scopus 로고
    • Defective excitation- contraction coupling in experimental cardiac hyper-trophy and heart failure
    • Gomez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, et al. Defective excitation- contraction coupling in experimental cardiac hyper-trophy and heart failure. Science. 1997;276:800-6.
    • (1997) Science , vol.276 , pp. 800-806
    • Gomez, A.M.1    Valdivia, H.H.2    Cheng, H.3    Lederer, M.R.4    Santana, L.F.5    Cannell, M.B.6
  • 21
    • 4344717030 scopus 로고    scopus 로고
    • Effects of long-term captopril and l-arginine treatment on ventilation and blood pressure in obese male shhf rats
    • Schlenker EH, Kost Jr CK, Likness MM. Effects of long-term captopril and L-arginine treatment on ventilation and blood pressure in obese male SHHF rats. J Appl Physiol. 2004;97:1032-9.
    • (2004) J Appl Physiol , vol.97 , pp. 1032-1039
    • Schlenker, E.H.1    Kost, C.K.2    Likness, M.M.3
  • 22
    • 1842597403 scopus 로고
    • Role of genetic fac-tors in susceptibility to experimental hypertension due to chronic excess salt ingestion
    • Dahl LK, Heine M, Tassinari L. Role of genetic fac-tors in susceptibility to experimental hypertension due to chronic excess salt ingestion. Nature. 1962;194:480-2.
    • (1962) Nature , vol.194 , pp. 480-482
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 23
    • 33646132038 scopus 로고    scopus 로고
    • Development of heart failure in chronic hypertensive dahl rats: Focus on heart failure with preserved ejection fraction
    • Klotz S, Hay I, Zhang G, Maurer M, Wang J, Burkhoff D. Development of heart failure in chronic hypertensive Dahl rats: focus on heart failure with preserved ejection fraction. Hypertension. 2006;47:901-11.
    • (2006) Hypertension , vol.47 , pp. 901-911
    • Klotz, S.1    Hay, I.2    Zhang, G.3    Maurer, M.4    Wang, J.5    Burkhoff, D.6
  • 24
    • 0028566018 scopus 로고
    • Transition from compensatory hypertrophy to dilated, failing left ventricles in dahl salt-sensitive rats
    • Inoko M, Kihara Y, Morii I, Fujiwara H, Sasayama S. Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats. Am J Physiol. 1994;267:H2471-82.
    • (1994) Am J Physiol , vol.267 , pp. H2471-H2H82
    • Inoko, M.1    Kihara, Y.2    Morii, I.3    Fujiwara, H.4    Sasayama, S.5
  • 25
    • 0033974788 scopus 로고    scopus 로고
    • Development of different phenotypes of hypertensive heart failure: Systolic versus diastolic failure in dahl salt-sensitive rats
    • Doi R, Masuyama T, Yamamoto K, Doi Y, Mano T, Sakata Y, et al. Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt-sensitive rats. J Hypertens. 2000;18:111-20.
    • (2000) J Hypertens , vol.18 , pp. 111-120
    • Doi, R.1    Masuyama, T.2    Yamamoto, K.3    Doi, Y.4    Mano, T.5    Sakata, Y.6
  • 26
    • 15244361791 scopus 로고    scopus 로고
    • Historic perspectives and recent advances in major animal models of hypertension
    • Sun ZJ, Zhang ZE. Historic perspectives and recent advances in major animal models of hypertension. Acta Pharmacol Sin. 2005;26:295-301.
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 295-301
    • Sun, Z.J.1    Zhang, Z.E.2
  • 27
    • 33744910056 scopus 로고    scopus 로고
    • Chronic angiotensin-(1-7) prevents cardiac fibrosis in doca-salt model of hypertension
    • Grobe JL, Mecca AP, Mao H, Katovich MJ. Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension. Am J Physiol Heart Circ Physiol. 2006;290:H2417-23.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H2417-H2H23
    • Grobe, J.L.1    Mecca, A.P.2    Mao, H.3    Katovich, M.J.4
  • 29
    • 0345465893 scopus 로고    scopus 로고
    • Blood pressure and small arteries in doca-salt-treated genetically avp-deficient rats: Role of endothelin
    • Intengan HD, Park JB, Schiffrin EL. Blood pressure and small arteries in DOCA-salt-treated genetically AVP-deficient rats: role of endothelin. Hypertension. 1999;34:907-13.
    • (1999) Hypertension , vol.34 , pp. 907-913
    • Intengan, H.D.1    Park, J.B.2    Schiffrin, E.L.3
  • 30
    • 0028585943 scopus 로고
    • Central effects of mineralocorticoid antagonist ru-28318 on blood pressure of doca-salt hypertensive rats
    • Van den Berg DT, de Kloet ER, de Jong W. Central effects of mineralocorticoid antagonist RU-28318 on blood pressure of DOCA-salt hypertensive rats. Am J Physiol. 1994;267:E927-33.
    • (1994) Am J Physiol , vol.267 , pp. E927-EE33
    • Van Den Berg, D.T.1    De Kloet, E.R.2    De Jong, W.3
  • 31
    • 0034993096 scopus 로고    scopus 로고
    • Role of endothelin-1 in hypertension and vascular disease
    • Schiffrin EL. Role of endothelin-1 in hypertension and vascular disease. Am J Hypertens. 2001;14:83S-9.
    • (2001) Am J Hypertens , vol.14 , pp. 83S-9S
    • Schiffrin, E.L.1
  • 32
    • 0242693904 scopus 로고    scopus 로고
    • Endothelin-1 stimulates arterial vcam-1 expression via nadph oxidase-derived superoxide in mineralocorticoid hypertension
    • Li L, Chu Y, Fink GD, Engelhardt JF, Heistad DD, Chen AF. Endothelin-1 stimulates arterial VCAM-1 expression via NADPH oxidase-derived superoxide in mineralocorticoid hypertension. Hypertension. 2003;42:997-1003.
    • (2003) Hypertension , vol.42 , pp. 997-1003
    • Li, L.1    Chu, Y.2    Fink, G.D.3    Engelhardt, J.F.4    Heistad, D.D.5    Chen, A.F.6
  • 33
    • 0019223087 scopus 로고
    • Importance of renal sympathetic tone in the development of doca-salt hypertension in the rat
    • Katholi RE, Naftilan AJ, Oparil S. Importance of renal sympathetic tone in the development of DOCA-salt hypertension in the rat. Hypertension. 1980;2:266-73.
    • (1980) Hypertension , vol.2 , pp. 266-273
    • Katholi, R.E.1    Naftilan, A.J.2    Oparil, S.3
  • 34
    • 0034081620 scopus 로고    scopus 로고
    • Cardiac and vascular responses in deoxycorticosterone acetate-salt hypertensive rats
    • Brown L, Ooi SY, Lau K, Sernia C. Cardiac and vascular responses in deoxycorticosterone acetate-salt hypertensive rats. Clin Exp Pharmacol Physiol. 2000;27:263-9.
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 263-269
    • Brown, L.1    Ooi, S.Y.2    Lau, K.3    Sernia, C.4
  • 35
    • 77955172275 scopus 로고    scopus 로고
    • Mineralocorticoid accel-erates transition to heart failure with preserved ejec-tion fraction via –nongenomic effects—
    • Mohammed SF, Ohtani T, Korinek J, Lam CS, Larsen K, Simari RD, et al. Mineralocorticoid accel-erates transition to heart failure with preserved ejec-tion fraction via –nongenomic effects—. Circulation. 2010;122:370-8.
    • (2010) Circulation , vol.122 , pp. 370-378
    • Mohammed, S.F.1    Ohtani, T.2    Korinek, J.3    Lam, C.S.4    Larsen, K.5    Simari, R.D.6
  • 36
    • 85024286205 scopus 로고
    • Studies on experimental hypertension: I. the pro-duction of persistent elevation of systolic blood pressure by means of renal ischemia
    • Goldblatt H, Lynch J, Hanzal RF, Summerville WW. Studies on experimental hypertension: I. The pro-duction of persistent elevation of systolic blood pressure by means of renal ischemia. J Exp Med. 1934;59:347-79.
    • (1934) J Exp Med , vol.59 , pp. 347-379
    • Goldblatt, H.1    Lynch, J.2    Hanzal, R.F.3    Summerville, W.W.4
  • 37
    • 44649143770 scopus 로고    scopus 로고
    • Proteomic analysis of left ventricular diastolic dysfunction hearts in renovascular hypertensive rats
    • Junhong W, Jing Y, Jizheng M, Shushu Z, Xiangjian C, Hengfang W, et al. Proteomic analysis of left ventricular diastolic dysfunction hearts in renovascular hypertensive rats. Int J Cardiol. 2008;127:198-207.
    • (2008) Int J Cardiol , vol.127 , pp. 198-207
    • Junhong, W.1    Jing, Y.2    Jizheng, M.3    Shushu, Z.4    Xiangjian, C.5    Hengfang, W.6
  • 38
    • 77953714931 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibi-tion improves cardiac dysfunction and remodeling in 2- kidney, 1-clip hypertension
    • Rizzi E, Castro MM, Prado CM, Silva CA, Fazan Jr R, Rossi MA, et al. Matrix metalloproteinase inhibi-tion improves cardiac dysfunction and remodeling in 2- kidney, 1-clip hypertension. J Card Fail. 2010;16:599-608.
    • (2010) J Card Fail , vol.16 , pp. 599-608
    • Rizzi, E.1    Castro, M.M.2    Prado, C.M.3    Silva, C.A.4    Fazan, R.5    Rossi, M.A.6
  • 39
    • 0018368578 scopus 로고
    • Effects of continuous converting enzyme blockade on renovascular hypertension in the rat
    • Freeman RH, Davis JO, Watkins BE, Stephens GA, DeForrest JM. Effects of continuous converting enzyme blockade on renovascular hypertension in the rat. Am J Physiol. 1979;236:F21-4.
    • (1979) Am J Physiol , vol.236 , pp. F21-FF4
    • Freeman, R.H.1    Davis, J.O.2    Watkins, B.E.3    Stephens, G.A.4    DeForrest, J.M.5
  • 40
    • 79954926044 scopus 로고    scopus 로고
    • Effects of chronic sympatho-inhibition on renal excretory function in renovascular hypertension
    • Burke SL, Evans RG, Head GA. Effects of chronic sympatho-inhibition on renal excretory function in renovascular hypertension. J Hypertens. 2011;29: 945-52.
    • (2011) J Hypertens , vol.29 , pp. 945-952
    • Burke, S.L.1    Evans, R.G.2    Head, G.A.3
  • 41
    • 0018605049 scopus 로고
    • Plasma renin activity and sodium, potassium and water excretion during reversal of hypertension in the one-clip two- kidney hypertensive rat
    • Berg RG, Leenen FH, de Jong W. Plasma renin activity and sodium, potassium and water excretion during reversal of hypertension in the one-clip two- kidney hypertensive rat. Clin Sci (Lond). 1979;57: 47-52.
    • (1979) Clin Sci (Lond) , vol.57 , pp. 47-52
    • Berg, R.G.1    Leenen, F.H.2    De Jong, W.3
  • 42
    • 0020317607 scopus 로고
    • Regression of left ventricular hypertrophy in two-kidney, one clip goldblatt hypertension
    • Kuwajima I, Kardon MB, Pegram BL, Sesoko S, Frohlich ED. Regression of left ventricular hypertrophy in two-kidney, one clip Goldblatt hypertension. Hypertension. 1982;4:113-8.
    • (1982) Hypertension , vol.4 , pp. 113-118
    • Kuwajima, I.1    Kardon, M.B.2    Pegram, B.L.3    Sesoko, S.4    Frohlich, E.D.5
  • 43
    • 84892633453 scopus 로고    scopus 로고
    • Myocardial titin hypo- phosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model
    • Hamdani N, Franssen C, Lourenco A, Falcao-Pires I, Fontoura D, Leite S, et al. Myocardial titin hypo- phosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model. Circ Heart Fail. 2013;6:1239-49.
    • (2013) Circ Heart Fail , vol.6 , pp. 1239-1249
    • Hamdani, N.1    Franssen, C.2    Lourenco, A.3    Falcao-Pires, I.4    Fontoura, D.5    Leite, S.6
  • 44
    • 84874115254 scopus 로고    scopus 로고
    • Murine models for pharmacological studies of the metabolic syndrome
    • Fellmann L, Nascimento AR, Tibirica E, Bousquet P. Murine models for pharmacological studies of the metabolic syndrome. Pharmacol Ther. 2013;137: 331-40.
    • (2013) Pharmacol Ther , vol.137 , pp. 331-340
    • Fellmann, L.1    Nascimento, A.R.2    Tibirica, E.3    Bousquet, P.4
  • 45
    • 0000736325 scopus 로고
    • Obese, a new mutation in the house mouse
    • Ingalls AM, Dickie MM, Snell GD. Obese, a new mutation in the house mouse. J Hered. 1950;41:317-8.
    • (1950) J Hered , vol.41 , pp. 317-318
    • Ingalls, A.M.1    Dickie, M.M.2    Snell, G.D.3
  • 46
    • 0014004384 scopus 로고
    • Diabetes, a new mutation in the mouse
    • Hummel KP, Dickie MM, Coleman DL. Diabetes, a new mutation in the mouse. Science. 1966;153:1127-8.
    • (1966) Science , vol.153 , pp. 1127-1128
    • Hummel, K.P.1    Dickie, M.M.2    Coleman, D.L.3
  • 47
    • 0041357130 scopus 로고    scopus 로고
    • Minimally invasive aortic banding in mice: Effects of altered cardiomyocyte insulin signaling during pressure overload
    • Hu P, Zhang D, Swenson L, Chakrabarti G, Abel ED, Litwin SE. Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload. Am J Physiol Heart Circ Physiol. 2003;285:H1261-9.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H1261-H12H9
    • Hu, P.1    Zhang, D.2    Swenson, L.3    Chakrabarti, G.4    Abel, E.D.5    Litwin, S.E.6
  • 48
    • 20044363270 scopus 로고    scopus 로고
    • Chronic inhibition of cyclic gmp phosphodiesterase 5a prevents and reverses cardiac hypertrophy
    • Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, et al. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med. 2005;11:214-22.
    • (2005) Nat Med , vol.11 , pp. 214-222
    • Takimoto, E.1    Champion, H.C.2    Li, M.3    Belardi, D.4    Ren, S.5    Rodriguez, E.R.6
  • 49
    • 80052807512 scopus 로고    scopus 로고
    • Bi-modal dose-depen-dent cardiac response to tetrahydrobiopterin in pres- sure-overload induced hypertrophy and heart failure
    • Moens AL, Ketner EA, Takimoto E, Schmidt TS, O’Neill CA, Wolin MS, et al. Bi-modal dose-depen-dent cardiac response to tetrahydrobiopterin in pres- sure-overload induced hypertrophy and heart failure. J Mol Cell Cardiol. 2011;51:564-9.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 564-569
    • Moens, A.L.1    Ketner, E.A.2    Takimoto, E.3    Schmidt, T.S.4    O’Neill, C.A.5    Wolin, M.S.6
  • 50
    • 70349755909 scopus 로고    scopus 로고
    • Adverse ventricular remodeling and exacerbated nos uncoupling from pressure-overload in mice lacking the beta3- adrenoreceptor
    • Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, et al. Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3- adrenoreceptor. J Mol Cell Cardiol. 2009;47:576-85.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 576-585
    • Moens, A.L.1    Leyton-Mange, J.S.2    Niu, X.3    Yang, R.4    Cingolani, O.5    Arkenbout, E.K.6
  • 52
    • 0028042562 scopus 로고
    • Ang ii receptor blockade prevents ventricular hypertrophy and anf gene expression with pressure overload in mice
    • Rockman HA, Wachhorst SP, Mao L, Ross Jr J. ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. Am J Physiol. 1994;266:H2468-75.
    • (1994) Am J Physiol , vol.266 , pp. H2468-H2H75
    • Rockman, H.A.1    Wachhorst, S.P.2    Mao, L.3    Ross, J.4
  • 53
    • 27644447015 scopus 로고    scopus 로고
    • Hypertension induced by aortic coarctation above the renal arteries is associated with immune cell infiltration of the kidneys
    • Rodriguez-Iturbe B, Quiroz Y, Kim CH, Vaziri ND. Hypertension induced by aortic coarctation above the renal arteries is associated with immune cell infiltration of the kidneys. Am J Hypertens. 2005;18:1449-56.
    • (2005) Am J Hypertens , vol.18 , pp. 1449-1456
    • Rodriguez-Iturbe, B.1    Quiroz, Y.2    Kim, C.H.3    Vaziri, N.D.4
  • 56
    • 85047676023 scopus 로고
    • Simple, rapid, and effective method of producing aortocaval shunts in the rat
    • Garcia R, Diebold S. Simple, rapid, and effective method of producing aortocaval shunts in the rat. Cardiovasc Res. 1990;24:430-2.
    • (1990) Cardiovasc Res , vol.24 , pp. 430-432
    • Garcia, R.1    Diebold, S.2
  • 57
    • 33750704623 scopus 로고    scopus 로고
    • Gender-related differences in left ventricular remodeling in chronic severe aortic valve regurgitation in rats
    • Drolet MC, Lachance D, Plante E, Roussel E, Couet J, Arsenault M. Gender-related differences in left ventricular remodeling in chronic severe aortic valve regurgitation in rats. J Heart Valve Dis. 2006;15: 345-51.
    • (2006) J Heart Valve Dis , vol.15 , pp. 345-351
    • Drolet, M.C.1    Lachance, D.2    Plante, E.3    Roussel, E.4    Couet, J.5    Arsenault, M.6
  • 58
    • 34547852332 scopus 로고    scopus 로고
    • Animal models of dilated cardiomyopathy for translational research
    • Recchia FA, Lionetti V. Animal models of dilated cardiomyopathy for translational research. Vet Res Commun. 2007;31 Suppl 1:35-41.
    • (2007) Vet Res Commun , vol.1 , pp. 35-41
    • Recchia, F.A.1    Lionetti, V.2
  • 59
    • 22544471568 scopus 로고    scopus 로고
    • The cardio- toxicology of anthracycline chemotherapeutics: Translating molecular mechanism into preventative medicine
    • Peng X, Chen B, Lim CC, Sawyer DB. The cardio- toxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine. Mol Interv. 2005;5:163-71.
    • (2005) Mol Interv , vol.5 , pp. 163-171
    • Peng, X.1    Chen, B.2    Lim, C.C.3    Sawyer, D.B.4
  • 60
    • 15944368682 scopus 로고    scopus 로고
    • Animal models of heart failure: What is new?
    • Monnet E, Chachques JC. Animal models of heart failure: what is new? Ann Thorac Surg. 2005;79: 1445-53.
    • (2005) Ann Thorac Surg , vol.79 , pp. 1445-1453
    • Monnet, E.1    Chachques, J.C.2
  • 61
    • 84861325625 scopus 로고    scopus 로고
    • Anthracycline cardiotox- icity: Prevalence, pathogenesis and treatment
    • Volkova M, Russell 3rd R. Anthracycline cardiotox- icity: prevalence, pathogenesis and treatment. Curr Cardiol Rev. 2011;7:214-20.
    • (2011) Curr Cardiol Rev , vol.7 , pp. 214-220
    • Volkova, M.1    Russell, R.2
  • 62
    • 0037236642 scopus 로고    scopus 로고
    • Melusin, a muscle-specific inte- grin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
    • Brancaccio M, et al. Melusin, a muscle-specific inte- grin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat Med. 2003;9(1):68-75.
    • (2003) Nat Med , vol.9 , Issue.1 , pp. 68-75
    • Brancaccio, M.1
  • 63
    • 0030933063 scopus 로고    scopus 로고
    • Mlp-deficient mice exhibit a disrup-tion of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure
    • Arber S, et al. MLP-deficient mice exhibit a disrup-tion of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 1997;88(3): 393-403.
    • (1997) Cell , vol.88 , Issue.3 , pp. 393-403
    • Arber, S.1
  • 64
    • 0142058043 scopus 로고    scopus 로고
    • Mutations in the muscle lim protein and alpha-actinin-2 genes in dilated cardio-myopathy and endocardial fibroelastosis
    • Mohapatra B, et al. Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardio-myopathy and endocardial fibroelastosis. Mol Genet Metab. 2003;80(1-2):207-15.
    • (2003) Mol Genet Metab , vol.80 , Issue.1-2 , pp. 207-215
    • Mohapatra, B.1
  • 65
    • 0034976642 scopus 로고    scopus 로고
    • The molecular genetic basis for hypertrophic cardiomyopathy
    • Marian AJ, Roberts R. The molecular genetic basis for hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2001;33(4):655-70.
    • (2001) J Mol Cell Cardiol , vol.33 , Issue.4 , pp. 655-670
    • Marian, A.J.1    Roberts, R.2
  • 66
    • 0035936792 scopus 로고    scopus 로고
    • The genetic basis for car-diomyopathy: From mutation identification to mechanistic paradigms
    • Seidman JG, Seidman C. The genetic basis for car-diomyopathy: from mutation identification to mechanistic paradigms. Cell. 2001;104(4):557-67.
    • (2001) Cell , vol.104 , Issue.4 , pp. 557-567
    • Seidman, J.G.1    Seidman, C.2
  • 67
    • 0029738727 scopus 로고    scopus 로고
    • Disruption of muscle architecture and myocardial degeneration in mice lacking des- min
    • Milner DJ, et al. Disruption of muscle architecture and myocardial degeneration in mice lacking des- min. J Cell Biol. 1996;134(5):1255-70.
    • (1996) J Cell Biol , vol.134 , Issue.5 , pp. 1255-1270
    • Milner, D.J.1
  • 68
    • 17344361902 scopus 로고    scopus 로고
    • A missense mutation in the alphab- crystallin chaperone gene causes a desmin-related myopathy
    • Vicart P, et al. A missense mutation in the alphaB- crystallin chaperone gene causes a desmin-related myopathy. Nat Genet. 1998;20(1):92-5.
    • (1998) Nat Genet , vol.20 , Issue.1 , pp. 92-95
    • Vicart, P.1
  • 69
    • 0031001970 scopus 로고    scopus 로고
    • Rescue of cardiac alpha-actin-defi- cient mice by enteric smooth muscle gamma-actin
    • Kumar A, et al. Rescue of cardiac alpha-actin-defi- cient mice by enteric smooth muscle gamma-actin. Proc Natl Acad Sci U S A. 1997;94(9):4406-11.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.9 , pp. 4406-4411
    • Kumar, A.1
  • 70
    • 0030848338 scopus 로고    scopus 로고
    • Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: A model for duchenne muscular dystrophy
    • Grady RM, et al. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell. 1997;90(4):729-38.
    • (1997) Cell , vol.90 , Issue.4 , pp. 729-738
    • Grady, R.M.1
  • 71
    • 0027940368 scopus 로고
    • Myocardial expression of a constitutively active alpha 1b-adrenergic receptor in transgenic mice induces cardiac hypertrophy
    • Milano CA, et al. Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc Natl Acad Sci U S A. 1994;91(21):10109-13.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.21 , pp. 10109-10113
    • Milano, C.A.1
  • 72
    • 0030764950 scopus 로고    scopus 로고
    • Transgenic mice with cardiac over-expression of alpha1b-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling
    • Akhter SA, et al. Transgenic mice with cardiac over-expression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling. J Biol Chem. 1997;272(34): 21253-9.
    • (1997) J Biol Chem , vol.272 , Issue.34 , pp. 21253-21259
    • Akhter, S.A.1
  • 73
    • 0037027468 scopus 로고    scopus 로고
    • Sympathetic nervous system in heart fail-ure
    • Cohn JN. Sympathetic nervous system in heart fail-ure. Circulation. 2002;106(19):2417-8.
    • (2002) Circulation , vol.106 , Issue.19 , pp. 2417-2418
    • Cohn, J.N.1
  • 74
    • 7444251699 scopus 로고    scopus 로고
    • Murine models for the study of congestive heart failure: Implications for understanding molecular mechanisms and for drug discovery
    • Wang QD, Bohlooly YM, Sjoquist PO. Murine models for the study of congestive heart failure: implications for understanding molecular mechanisms and for drug discovery. J Pharmacol Toxicol Methods. 2004;50(3):163-74.
    • (2004) J Pharmacol Toxicol Methods , vol.50 , Issue.3 , pp. 163-174
    • Wang, Q.D.1    Bohlooly, Y.M.2    Sjoquist, P.O.3
  • 75
    • 0037027480 scopus 로고    scopus 로고
    • Feedback inhibition of catechol-amine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure
    • Brede M, et al. Feedback inhibition of catechol-amine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure. Circulation. 2002;106(19):2491-6.
    • (2002) Circulation , vol.106 , Issue.19 , pp. 2491-2496
    • Brede, M.1
  • 76
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
    • Engelhardt S, et al. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA. 1999;96(12): 7059-64.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.12 , pp. 7059-7064
    • Engelhardt, S.1
  • 77
    • 0035656783 scopus 로고    scopus 로고
    • Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic recep-tor
    • Engelhardt S, et al. Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic recep-tor. FASEB J. 2001;15(14):2718-20.
    • (2001) FASEB J , vol.15 , Issue.14 , pp. 2718-2720
    • Engelhardt, S.1
  • 78
    • 0036278538 scopus 로고    scopus 로고
    • Junctional sarcoplasmic reticulum transmembrane proteins in the heart
    • Muller FU, et al. Junctional sarcoplasmic reticulum transmembrane proteins in the heart. Basic Res Cardiol. 2002;97 Suppl 1:I52-5.
    • (2002) Basic Res Cardiol , vol.1 , Issue.97 , pp. I52-II5
    • Muller, F.U.1
  • 79
    • 1542409908 scopus 로고    scopus 로고
    • Altered calcium handling is criti-cally involved in the cardiotoxic effects of chronic beta-adrenergic stimulation
    • Engelhardt S, et al. Altered calcium handling is criti-cally involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation. 2004;109(9): 1154-60.
    • (2004) Circulation , vol.109 , Issue.9 , pp. 1154-1160
    • Engelhardt, S.1
  • 80
    • 0038464639 scopus 로고    scopus 로고
    • Phospholamban: A crucial regulator of cardiac contractility
    • MacLennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol. 2003;4(7):566-77.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.7 , pp. 566-577
    • MacLennan, D.H.1    Kranias, E.G.2
  • 81
    • 0037352911 scopus 로고    scopus 로고
    • Altered calcium transient and development of hypertrophy in beta2-adrenoceptor overexpressing mice with and without pressure overload
    • Schwarz B, et al. Altered calcium transient and development of hypertrophy in beta2-adrenoceptor overexpressing mice with and without pressure overload. Eur J Heart Fail. 2003;5(2):131-6.
    • (2003) Eur J Heart Fail , vol.5 , Issue.2 , pp. 131-136
    • Schwarz, B.1
  • 82
    • 0025273198 scopus 로고
    • Evidence against spare or uncoupled beta-adrenoceptors in the human heart
    • Schwinger RH, Bohm M, Erdmann E. Evidence against spare or uncoupled beta-adrenoceptors in the human heart. Am Heart J. 1990;119(4):899-904.
    • (1990) Am Heart J , vol.119 , Issue.4 , pp. 899-904
    • Schwinger, R.H.1    Bohm, M.2    Erdmann, E.3
  • 83
    • 0034602839 scopus 로고    scopus 로고
    • Beta(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis
    • Du XJ, et al. beta(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis. Circulation. 2000;101(1):71-7.
    • (2000) Circulation , vol.101 , Issue.1 , pp. 71-77
    • Du, X.J.1
  • 84
    • 0028882650 scopus 로고
    • Unchanged protein levels of serca ii and phospholamban but reduced ca2+ uptake and ca(2+)-atpase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts
    • Schwinger RH, et al. Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. Circulation. 1995;92(11):3220-8.
    • (1995) Circulation , vol.92 , Issue.11 , pp. 3220-3228
    • Schwinger, R.H.1
  • 85
    • 33745379908 scopus 로고    scopus 로고
    • Response to cardiac sympathetic activation in transgenic mice overexpressing beta 2-adren- ergic receptor
    • Du XJ, et al. Response to cardiac sympathetic activation in transgenic mice overexpressing beta 2-adren- ergic receptor. Am J Physiol. 1996;271(2 Pt 2):H630-6.
    • (1996) Am J Physiol , vol.271 , Issue.2 , pp. H630-H6H6
    • Du, X.J.1
  • 86
    • 0028799640 scopus 로고
    • Marked enhancement in myocar-dial function resulting from overexpression of a human beta-adrenergic receptor gene
    • Milano CA, et al. Marked enhancement in myocar-dial function resulting from overexpression of a human beta-adrenergic receptor gene. J Thorac Cardiovasc Surg. 1995;109(2):236-41.
    • (1995) J Thorac Cardiovasc Surg , vol.109 , Issue.2 , pp. 236-241
    • Milano, C.A.1
  • 87
    • 0031105748 scopus 로고    scopus 로고
    • Functional analysis of myocardial performance in murine hearts overexpressing the human beta 2-adrenergic receptor
    • Bittner HB, et al. Functional analysis of myocardial performance in murine hearts overexpressing the human beta 2-adrenergic receptor. J Mol Cell Cardiol. 1997;29(3):961-7.
    • (1997) J Mol Cell Cardiol , vol.29 , Issue.3 , pp. 961-967
    • Bittner, H.B.1
  • 88
    • 0028987954 scopus 로고
    • Physiological effects of inverse ago-nists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor
    • Bond RA, et al. Physiological effects of inverse ago-nists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor. Nature. 1995;374(6519):272-6.
    • (1995) Nature , vol.374 , Issue.6519 , pp. 272-276
    • Bond, R.A.1
  • 89
    • 0033461786 scopus 로고    scopus 로고
    • Constitutive beta2-adrenergic signalling enhances sarcoplasmic reticulum ca2+ cycling to augment contraction in mouse heart
    • Zhou YY, et al. Constitutive beta2-adrenergic signalling enhances sarcoplasmic reticulum Ca2+ cycling to augment contraction in mouse heart. J Physiol. 1999;521(Pt 2):351-61.
    • (1999) J Physiol , vol.521 , pp. 351-361
    • Zhou, Y.Y.1
  • 90
    • 0033546313 scopus 로고    scopus 로고
    • Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2- adrenergic receptors
    • Rohrer DK, et al. Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2- adrenergic receptors. J Biol Chem. 1999;274(24): 16701-8.
    • (1999) J Biol Chem , vol.274 , Issue.24 , pp. 16701-16708
    • Rohrer, D.K.1
  • 91
    • 0033710840 scopus 로고    scopus 로고
    • Age-dependent cardiomyopathy and heart failure phenotype in mice overexpressing beta(2)-adrenergic receptors in the heart
    • Du XJ, et al. Age-dependent cardiomyopathy and heart failure phenotype in mice overexpressing beta(2)-adrenergic receptors in the heart. Cardiovasc Res. 2000;48(3):448-54.
    • (2000) Cardiovasc Res , vol.48 , Issue.3 , pp. 448-454
    • Du, X.J.1
  • 92
    • 0034636061 scopus 로고    scopus 로고
    • Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: Critical role for expression level
    • Liggett SB, et al. Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation. 2000;101(14):1707-14.
    • (2000) Circulation , vol.101 , Issue.14 , pp. 1707-1714
    • Liggett, S.B.1
  • 93
    • 0029061324 scopus 로고
    • Cardiac function in mice overex pressing the beta-adrenergic receptor kinase or a beta ark inhibitor
    • Koch WJ, et al. Cardiac function in mice overex pressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science. 1995;268(5215):1350-3.
    • (1995) Science , vol.268 , Issue.5215 , pp. 1350-1353
    • Koch, W.J.1
  • 94
    • 0032499733 scopus 로고    scopus 로고
    • Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
    • Rockman HA, et al. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci U S A. 1998;95(12):7000-5.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.12 , pp. 7000-7005
    • Rockman, H.A.1
  • 95
    • 0035826710 scopus 로고    scopus 로고
    • Cardiac beta ark1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure
    • Harding VB, et al. Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proc Natl Acad Sci U S A. 2001;98(10):5809-14.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.10 , pp. 5809-5814
    • Harding, V.B.1
  • 96
    • 0034681187 scopus 로고    scopus 로고
    • Overexpression of angiotensin ii type i receptor in cardiomyocytes induces cardiac hypertrophy and remodeling
    • Paradis P, et al. Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci U S A. 2000;97(2):931-6.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.2 , pp. 931-936
    • Paradis, P.1
  • 97
    • 0030763808 scopus 로고    scopus 로고
    • Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha
    • Kubota T, et al. Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha. Circ Res. 1997;81(4):627-35.
    • (1997) Circ Res , vol.81 , Issue.4 , pp. 627-635
    • Kubota, T.1
  • 98
    • 0037197796 scopus 로고    scopus 로고
    • Pfeffer ma. New therapeutic options in congestive heart failure: Part i
    • McMurray J, Pfeffer MA. New therapeutic options in congestive heart failure: Part I. Circulation. 2002;105(17):2099-106.
    • (2002) Circulation , vol.105 , Issue.17 , pp. 2099-2106
    • McMurray, J.1
  • 99
    • 0037035467 scopus 로고    scopus 로고
    • Pfeffer ma. New therapeutic options in congestive heart failure: Part ii
    • McMurray J, Pfeffer MA. New therapeutic options in congestive heart failure: Part II. Circulation. 2002;105(18):2223-8.
    • (2002) Circulation , vol.105 , Issue.18 , pp. 2223-2228
    • McMurray, J.1
  • 100
    • 0033574574 scopus 로고    scopus 로고
    • Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
    • Hirota H, et al. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. 1999;97(2):189-98.
    • (1999) Cell , vol.97 , Issue.2 , pp. 189-198
    • Hirota, H.1
  • 101
    • 0028997843 scopus 로고
    • Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
    • Hirota H, et al. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci U S A. 1995;92(11):4862-6.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.11 , pp. 4862-4866
    • Hirota, H.1
  • 102
    • 0030610854 scopus 로고    scopus 로고
    • Transgenic galphaq overex-pression induces cardiac contractile failure in mice
    • D’Angelo DD, et al. Transgenic Galphaq overex-pression induces cardiac contractile failure in mice. Proc Natl Acad Sci U S A. 1997;94(15):8121-6.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.15 , pp. 8121-8126
    • D’Angelo, D.D.1
  • 103
    • 0036143851 scopus 로고    scopus 로고
    • Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress
    • Esposito G, et al. Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation. 2002;105(1):85-92.
    • (2002) Circulation , vol.105 , Issue.1 , pp. 85-92
    • Esposito, G.1
  • 104
    • 0032506233 scopus 로고    scopus 로고
    • Transient cardiac expression of constitutively active galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways
    • Mende U, et al. Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc Natl Acad Sci U S A. 1998;95(23):13893-8.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.23 , pp. 13893-13898
    • Mende, U.1
  • 105
    • 0032562289 scopus 로고    scopus 로고
    • Targeting the receptor-gq interface to inhibit in vivo pressure overload myocardial hypertrophy
    • Akhter SA, et al. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998;280(5363):574-7.
    • (1998) Science , vol.280 , Issue.5363 , pp. 574-577
    • Akhter, S.A.1
  • 106
    • 0035166852 scopus 로고    scopus 로고
    • Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of galphaq/galpha11 in cardiomyo- cytes
    • Wettschureck N, et al. Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyo- cytes. Nat Med. 2001;7(11):1236-40.
    • (2001) Nat Med , vol.7 , Issue.11 , pp. 1236-1240
    • Wettschureck, N.1
  • 107
    • 0029912925 scopus 로고    scopus 로고
    • Adverse effects of chronic endoge-nous sympathetic drive induced by cardiac gs alpha overexpression
    • Iwase M, et al. Adverse effects of chronic endoge-nous sympathetic drive induced by cardiac GS alpha overexpression. Circ Res. 1996;78(4):517-24.
    • (1996) Circ Res , vol.78 , Issue.4 , pp. 517-524
    • Iwase, M.1
  • 108
    • 0034712586 scopus 로고    scopus 로고
    • Conditional expression of a gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy
    • Redfern CH, et al. Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. Proc Natl Acad Sci U S A. 2000;97(9):4826-31.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.9 , pp. 4826-4831
    • Redfern, C.H.1
  • 109
    • 0029091356 scopus 로고
    • Ventricular expression of a mlc- 2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice
    • Hunter JJ, et al. Ventricular expression of a MLC- 2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. J Biol Chem. 1995;270(39):23173-8.
    • (1995) J Biol Chem , vol.270 , Issue.39 , pp. 23173-23178
    • Hunter, J.J.1
  • 110
    • 0032694585 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of rhoa results in sinus and atrioventricular nodal dysfunction and contractile failure
    • Sah VP, et al. Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure. J Clin Invest. 1999;103(12):1627-34.
    • (1999) J Clin Invest , vol.103 , Issue.12 , pp. 1627-1634
    • Sah, V.P.1
  • 111
    • 0034120364 scopus 로고    scopus 로고
    • Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1
    • Sussman MA, et al. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. J Clin Invest. 2000;105(7): 875-86.
    • (2000) J Clin Invest , vol.105 , Issue.7 , pp. 875-886
    • Sussman, M.A.1
  • 112
    • 0030875166 scopus 로고    scopus 로고
    • Etal. Targeted overexpression of protein kinase c beta2 isoform in myocardium causes cardiomyopathy
    • Wakasaki H, etal. Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy. Proc Natl Acad Sci U S A. 1997;94(17): 9320-5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.17 , pp. 9320-9325
    • Wakasaki, H.1
  • 113
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent tran-scriptional pathway for cardiac hypertrophy
    • Molkentin JD, et al. A calcineurin-dependent tran-scriptional pathway for cardiac hypertrophy. Cell. 1998;93(2):215-28.
    • (1998) Cell , vol.93 , Issue.2 , pp. 215-228
    • Molkentin, J.D.1
  • 114
    • 33746825412 scopus 로고    scopus 로고
    • Picot inhibits cardiac hypertrophy and enhances ventricular function and cardiomyo- cyte contractility
    • Jeong D, et al. PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyo- cyte contractility. Circ Res. 2006;99(3):307-14.
    • (2006) Circ Res , vol.99 , Issue.3 , pp. 307-314
    • Jeong, D.1
  • 115
    • 0034705485 scopus 로고    scopus 로고
    • Transgenic overexpression of constitutively active protein kinase c epsilon causes concentric cardiac hypertrophy
    • Takeishi Y, et al. Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy. Circ Res. 2000;86(12): 1218-23.
    • (2000) Circ Res , vol.86 , Issue.12 , pp. 1218-1223
    • Takeishi, Y.1
  • 116
    • 0035941418 scopus 로고    scopus 로고
    • Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a
    • Antos CL, et al. Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a. Circ Res. 2001;89(11):997-1004.
    • (2001) Circ Res , vol.89 , Issue.11 , pp. 997-1004
    • Antos, C.L.1
  • 117
    • 66449097490 scopus 로고    scopus 로고
    • Requirement for ca2+/calmodulin- dependent kinase ii in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
    • Ling H, et al. Requirement for Ca2+/calmodulin- dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009;119(5):1230-40.
    • (2009) J Clin Invest , vol.119 , Issue.5 , pp. 1230-1240
    • Ling, H.1
  • 118
    • 15244345086 scopus 로고    scopus 로고
    • Calmodulin kinase signaling in heart: An intriguing candidate target for therapy of myocardial dysfunction and arrhythmias
    • Anderson ME. Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias. Pharmacol Ther. 2005;106(1):39-55.
    • (2005) Pharmacol Ther , vol.106 , Issue.1 , pp. 39-55
    • Anderson, M.E.1
  • 119
    • 70349613570 scopus 로고    scopus 로고
    • Beta1-adrenergic receptors stimulate cardiac contractility and camkii activation in vivo and enhance cardiac dysfunction following myocardial infarction
    • Yoo B, et al. Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol. 2009;297(4):H1377-86.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , Issue.4 , pp. H1377-H1H86
    • Yoo, B.1
  • 120
    • 0027234582 scopus 로고
    • Targeted developmental overex-pression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in trans-genic mice
    • Gruver CL, et al. Targeted developmental overex-pression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in trans-genic mice. Endocrinology. 1993;133(1):376-88.
    • (1993) Endocrinology , vol.133 , Issue.1 , pp. 376-388
    • Gruver, C.L.1
  • 121
    • 0035830362 scopus 로고    scopus 로고
    • A ca(2+)-dependent transgenic model of cardiac hypertrophy: A role for protein kinase calpha
    • Muth JN, et al. A Ca(2+)-dependent transgenic model of cardiac hypertrophy: a role for protein kinase Calpha. Circulation. 2001;103(1):140-7.
    • (2001) Circulation , vol.103 , Issue.1 , pp. 140-147
    • Muth, J.N.1
  • 122
    • 0032038691 scopus 로고    scopus 로고
    • Regulation of ca2+ signaling in transgenic mouse cardiac myocytes overexpress-ing calsequestrin
    • Jones LR, et al. Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpress-ing calsequestrin. J Clin Invest. 1998; 101 (7): 1385-93.
    • (1998) J Clin Invest , vol.101 , Issue.7 , pp. 1385-1393
    • Jones, L.R.1
  • 123
    • 0032561337 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice
    • Sato Y, et al. Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice. J Biol Chem. 1998;273(43):28470-7.
    • (1998) J Biol Chem , vol.273 , Issue.43 , pp. 28470-28477
    • Sato, Y.1
  • 124
    • 0033593328 scopus 로고    scopus 로고
    • Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(Endo)plasmic reticulum ca2 + -atpase iso-form 2 (serca2) gene
    • Periasamy M, et al. Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2 + -ATPase iso-form 2 (SERCA2) gene. J Biol Chem. 1999;274(4): 2556-62.
    • (1999) J Biol Chem , vol.274 , Issue.4 , pp. 2556-2562
    • Periasamy, M.1
  • 125
    • 0035980164 scopus 로고    scopus 로고
    • Transgenic expression of sarcoplasmic reticulum ca(2+) atpase modifies the transition from hypertrophy to early heart failure
    • Ito K, et al. Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure. Circ Res. 2001;89(5):422-9.
    • (2001) Circ Res , vol.89 , Issue.5 , pp. 422-429
    • Ito, K.1
  • 126
    • 61949300248 scopus 로고    scopus 로고
    • Rescue of ca2+ overload-induced left ventricular dysfunction by targeted ablation of phos- pholamban
    • Tsuji T, et al. Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phos- pholamban. Am J Physiol Heart Circ Physiol. 2009;296(2):H310-7.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , Issue.2 , pp. H310-H3H7
    • Tsuji, T.1
  • 127
    • 0030805905 scopus 로고    scopus 로고
    • Overexpression of the rat sarcoplasmic reticulum ca2+ atpase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation
    • He H, et al. Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. J Clin Invest. 1997;100(2):380-9.
    • (1997) J Clin Invest , vol.100 , Issue.2 , pp. 380-389
    • He, H.1
  • 128
    • 0032576586 scopus 로고    scopus 로고
    • Targeted overexpression of the sarcoplasmic reticulum ca2 + -atpase increases cardiac contractility in transgenic mouse hearts
    • Baker DL, et al. Targeted overexpression of the sarcoplasmic reticulum Ca2 + -ATPase increases cardiac contractility in transgenic mouse hearts. Circ Res. 1998;83(12):1205-14.
    • (1998) Circ Res , vol.83 , Issue.12 , pp. 1205-1214
    • Baker, D.L.1
  • 129
    • 0037470512 scopus 로고    scopus 로고
    • Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban
    • Schmitt JP, et al. Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science. 2003;299(5611):1410-3.
    • (2003) Science , vol.299 , Issue.5611 , pp. 1410-1413
    • Schmitt, J.P.1
  • 130
    • 0035937762 scopus 로고    scopus 로고
    • Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation
    • Sato Y, et al. Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation. J Biol Chem. 2001;276(12):9392-9.
    • (2001) J Biol Chem , vol.276 , Issue.12 , pp. 9392-9399
    • Sato, Y.1
  • 131
    • 0035852663 scopus 로고    scopus 로고
    • Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality
    • Dash R, et al. Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality. Circulation. 2001;103(6): 889-96.
    • (2001) Circulation , vol.103 , Issue.6 , pp. 889-896
    • Dash, R.1
  • 132
    • 0027932798 scopus 로고
    • Targeted ablation of the phospholam- ban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation
    • Luo W, et al. Targeted ablation of the phospholam- ban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res. 1994;75(3):401-9.
    • (1994) Circ Res , vol.75 , Issue.3 , pp. 401-409
    • Luo, W.1
  • 133
    • 0033615645 scopus 로고    scopus 로고
    • Chronic phospholamban-sar- coplasmic reticulum calcium atpase interaction is the critical calcium cycling defect in dilated cardio-myopathy
    • Minamisawa S, et al. Chronic phospholamban-sar- coplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardio-myopathy. Cell. 1999;99(3):313-22.
    • (1999) Cell , vol.99 , Issue.3 , pp. 313-322
    • Minamisawa, S.1
  • 134
    • 28444499677 scopus 로고    scopus 로고
    • S100a1 gene therapy preserves in vivo cardiac function after myocardial infarction
    • Pleger ST, et al. S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction. Mol Ther. 2005;12(6):1120-9.
    • (2005) Mol Ther , vol.12 , Issue.6 , pp. 1120-1129
    • Pleger, S.T.1
  • 135
    • 0037149508 scopus 로고    scopus 로고
    • Oestrogen protects fkbp12.6 null mice from cardiac hypertrophy
    • Xin HB, et al. Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature. 2002;416(6878):334-8.
    • (2002) Nature , vol.416 , Issue.6878 , pp. 334-338
    • Xin, H.B.1
  • 136
    • 0037469180 scopus 로고    scopus 로고
    • Fkbp12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure
    • Yano M, et al. FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure. Circulation. 2003;107(3):477-84.
    • (2003) Circulation , vol.107 , Issue.3 , pp. 477-484
    • Yano, M.1
  • 137
    • 0037040839 scopus 로고    scopus 로고
    • Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure
    • Shai SY, et al. Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res. 2002;90(4): 458-64.
    • (2002) Circ Res , vol.90 , Issue.4 , pp. 458-464
    • Shai, S.Y.1
  • 138
    • 0041858010 scopus 로고    scopus 로고
    • Targeted deletion of mmp-2 attenuates early lv rupture and late remodeling after experimental myocardial infarction
    • Hayashidani S, et al. Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction. Am J Physiol Heart Circ Physiol. 2003;285(3):H1229-35.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , Issue.3 , pp. H1229-H1H35
    • Hayashidani, S.1
  • 139
    • 0033932709 scopus 로고    scopus 로고
    • Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
    • Ducharme A, et al. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106(1):55-62.
    • (2000) J Clin Invest , vol.106 , Issue.1 , pp. 55-62
    • Ducharme, A.1
  • 140
    • 0037230181 scopus 로고    scopus 로고
    • Deficiency of timp-1 exacer-bates lv remodeling after myocardial infarction in mice
    • Creemers EE, et al. Deficiency of TIMP-1 exacer-bates LV remodeling after myocardial infarction in mice. Am J Physiol Heart Circ Physiol. 2003;284(1):H364-71.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , Issue.1 , pp. H364-HH71
    • Creemers, E.E.1
  • 141
    • 77954684897 scopus 로고    scopus 로고
    • Model mice for tissue-specific deletion of the manganese superoxide dismutase gene
    • Shimizu T, et al. Model mice for tissue-specific deletion of the manganese superoxide dismutase gene. Geriatr Gerontol Int. 2010;10 Suppl 1:S70-9.
    • (2010) Geriatr Gerontol Int , vol.1 , Issue.10 , pp. S70-SS9
    • Shimizu, T.1
  • 142
    • 0036382661 scopus 로고    scopus 로고
    • Model mice for tissue-specific deletion of the manganese superoxide dismutase (Mnsod) gene
    • Ikegami T, et al. Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene. Biochem Biophys Res Commun. 2002;296(3):729-36.
    • (2002) Biochem Biophys Res Commun , vol.296 , Issue.3 , pp. 729-736
    • Ikegami, T.1
  • 143
    • 0036192939 scopus 로고    scopus 로고
    • Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
    • Belke DD, et al. Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J Clin Invest. 2002;109(5): 629-39.
    • (2002) J Clin Invest , vol.109 , Issue.5 , pp. 629-639
    • Belke, D.D.1
  • 144
    • 27644512904 scopus 로고    scopus 로고
    • Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: Possible role of reduced capillary density
    • McQueen AP, et al. Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density. J Mol Cell Cardiol. 2005;39(6):882-92.
    • (2005) J Mol Cell Cardiol , vol.39 , Issue.6 , pp. 882-892
    • McQueen, A.P.1
  • 145
    • 84899080736 scopus 로고    scopus 로고
    • Animal models of insulin resistance and heart failure
    • Velez M, Kohli S, Sabbah HN. Animal models of insulin resistance and heart failure. Heart Fail Rev. 2014;19(1):1-13.
    • (2014) Heart Fail Rev , vol.19 , Issue.1 , pp. 1-13
    • Velez, M.1    Kohli, S.2    Sabbah, H.N.3
  • 146
    • 72249100585 scopus 로고    scopus 로고
    • Type 1 diabetic cardiomyopathy in the akita (Ins2wt/c96y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
    • Basu R, et al. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am J Physiol Heart Circ Physiol. 2009;297(6):H2096-108.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , Issue.6 , pp. H2096-HH108
    • Basu, R.1
  • 147
    • 0030907296 scopus 로고    scopus 로고
    • A novel locus, mody4, distal to d7mit189 on chromosome 7 determines early-onset niddm in nonobese c57bl/6 (Akita) mutant mice
    • Yoshioka M, et al. A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes. 1997;46(5):887-94.
    • (1997) Diabetes , vol.46 , Issue.5 , pp. 887-894
    • Yoshioka, M.1
  • 148
    • 0024459130 scopus 로고
    • Calmodulin- induced early-onset diabetes in transgenic mice
    • Epstein PN, Overbeek PA, Means AR. Calmodulin- induced early-onset diabetes in transgenic mice. Cell. 1989;58(6):1067-73.
    • (1989) Cell , vol.58 , Issue.6 , pp. 1067-1073
    • Epstein, P.N.1    Overbeek, P.A.2    Means, A.R.3
  • 149
    • 6044224889 scopus 로고    scopus 로고
    • Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes
    • Shen X, et al. Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes. Am J Physiol Endocrinol Metab. 2004;287(5): E896-905.
    • (2004) Am J Physiol Endocrinol Metab , vol.287 , Issue.5 , pp. E896-E905
    • Shen, X.1
  • 150
    • 0028200910 scopus 로고
    • Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats
    • Teerlink JR, Pfeffer JM, Pfeffer MA. Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats. Circ Res. 1994;75:105-13.
    • (1994) Circ Res , vol.75 , pp. 105-113
    • Teerlink, J.R.1    Pfeffer, J.M.2    Pfeffer, M.A.3
  • 151
    • 15944418262 scopus 로고    scopus 로고
    • Probucol attenuates oxi-dative stress and energy decline in isoproterenol- induced heart failure in rat
    • El-Demerdash E, Awad AS, Taha RM, El-Hady AM, Sayed-Ahmed MM. Probucol attenuates oxi-dative stress and energy decline in isoproterenol- induced heart failure in rat. Pharmacol Res. 2005;51: 311-8.
    • (2005) Pharmacol Res , vol.51 , pp. 311-318
    • El-Demerdash, E.1    Awad, A.S.2    Taha, R.M.3    El-Hady, A.M.4    Sayed-Ahmed, M.M.5
  • 152
    • 0242381308 scopus 로고    scopus 로고
    • Phosphoinositide 3- kinase gamma-deficient mice are protected from isoproterenol-induced heart failure
    • Oudit GY, Crackower MA, Eriksson U, Sarao R, Kozieradzki I, Sasaki T, et al. Phosphoinositide 3- kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. Circulation. 2003;108:2147-52.
    • (2003) Circulation , vol.108 , pp. 2147-2152
    • Oudit, G.Y.1    Crackower, M.A.2    Eriksson, U.3    Sarao, R.4    Kozieradzki, I.5    Sasaki, T.6
  • 153
    • 0031912189 scopus 로고    scopus 로고
    • Development of heart failure following isoproterenol administration in the rat: Role of the renin-angiotensin system
    • Grimm D, Elsner D, Schunkert H, Pfeifer M, Griese D, Bruckschlegel G, et al. Development of heart failure following isoproterenol administration in the rat: role of the renin-angiotensin system. Cardiovasc Res. 1998;37:91-100.
    • (1998) Cardiovasc Res , vol.37 , pp. 91-100
    • Grimm, D.1    Elsner, D.2    Schunkert, H.3    Pfeifer, M.4    Griese, D.5    Bruckschlegel, G.6
  • 156
    • 0033984947 scopus 로고    scopus 로고
    • Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice
    • Gao XM, Dart AM, Dewar E, Jennings G, Du XJ. Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice. Cardiovasc Res. 2000;45:330-8.
    • (2000) Cardiovasc Res , vol.45 , pp. 330-338
    • Gao, X.M.1    Dart, A.M.2    Dewar, E.3    Jennings, G.4    Du, X.J.5
  • 157
    • 33745117304 scopus 로고    scopus 로고
    • Effects of kr-31378, a novel atp-sensitive potassium channel activator, on hypertrophy of h9c2 cells and on cardiac dysfunction in rats with congestive heart failure
    • Hwang GS, Oh KS, Koo HN, Seo HW, You KH, Lee BH. Effects of KR-31378, a novel ATP-sensitive potassium channel activator, on hypertrophy of H9c2 cells and on cardiac dysfunction in rats with congestive heart failure. Eur J Pharmacol. 2006;540:131-8.
    • (2006) Eur J Pharmacol , vol.540 , pp. 131-138
    • Hwang, G.S.1    Oh, K.S.2    Koo, H.N.3    Seo, H.W.4    You, K.H.5    Lee, B.H.6
  • 163
    • 57149142916 scopus 로고    scopus 로고
    • Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition
    • West MB, Rokosh G, Obal D, Velayutham M, Xuan YT, Hill BG, et al. Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation. 2008;118:1970-8.
    • (2008) Circulation , vol.118 , pp. 1970-1978
    • West, M.B.1    Rokosh, G.2    Obal, D.3    Velayutham, M.4    Xuan, Y.T.5    Hill, B.G.6
  • 164
    • 40149110478 scopus 로고    scopus 로고
    • Wide-spread myocardial remodeling after acute myocardial infarction in rat. Features for heart fail-ure progression
    • Krzeminski TF, Nozynski JK, Grzyb J, Porc M. Wide-spread myocardial remodeling after acute myocardial infarction in rat. Features for heart fail-ure progression. Vascul Pharmacol. 2008;48:100-8.
    • (2008) Vascul Pharmacol , vol.48 , pp. 100-108
    • Krzeminski, T.F.1    Nozynski, J.K.2    Grzyb, J.3    Porc, M.4
  • 165
    • 3242712216 scopus 로고    scopus 로고
    • Implantation of bone marrow mono-nuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium
    • Ryu JH, Kim IK, Cho SW, Cho MC, Hwang KK, Piao H, et al. Implantation of bone marrow mono-nuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium. Biomaterials. 2005;26:319-26.
    • (2005) Biomaterials , vol.26 , pp. 319-326
    • Ryu, J.H.1    Kim, I.K.2    Cho, S.W.3    Cho, M.C.4    Hwang, K.K.5    Piao, H.6
  • 166
    • 33746902380 scopus 로고    scopus 로고
    • Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis
    • Heymans S, Pauschinger M, De Palma A, Kallwellis- Opara A, Rutschow S, Swinnen M, et al. Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis. Circulation. 2006;114:565-73.
    • (2006) Circulation , vol.114 , pp. 565-573
    • Heymans, S.1    Pauschinger, M.2    De Palma, A.3    Kallwellis-Opara, A.4    Rutschow, S.5    Swinnen, M.6
  • 167
    • 0037120941 scopus 로고    scopus 로고
    • Left ventricular pressure-volume relationship in a murine model of congestive heart failure due to acute viral myocarditis
    • Nishio R, Sasayama S, Matsumori A. Left ventricular pressure-volume relationship in a murine model of congestive heart failure due to acute viral myocarditis. J Am Coll Cardiol. 2002;40:1506-14.
    • (2002) J am Coll Cardiol , vol.40 , pp. 1506-1514
    • Nishio, R.1    Sasayama, S.2    Matsumori, A.3
  • 168
    • 0029553242 scopus 로고
    • Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy-lessons from animal experiments
    • Matsumori A, Sasayama S. Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy-lessons from animal experiments. Eur Heart J. 1995;16:140-3.
    • (1995) Eur Heart J , vol.16 , pp. 140-143
    • Matsumori, A.1    Sasayama, S.2
  • 169
    • 0029550188 scopus 로고
    • The role of transgenic knockout models in defining the pathogenesis of viral heart disease
    • Liu P, Penninger J, Aitken K, Sole M, Mak T. The role of transgenic knockout models in defining the pathogenesis of viral heart disease. Eur Heart J. 1995;16:25-7.
    • (1995) Eur Heart J , vol.16 , pp. 25-27
    • Liu, P.1    Penninger, J.2    Aitken, K.3    Sole, M.4    Mak, T.5
  • 170
    • 25144458663 scopus 로고    scopus 로고
    • Cardiac gene expression profiling provides evidence for cytokin- opathy as a molecular mechanism in chagas’ disease cardiomyopathy
    • Cunha-Neto E, Dzau VJ, Allen PD, Stamatiou D, Benvenutti L, Higuchi ML, et al. Cardiac gene expression profiling provides evidence for cytokin- opathy as a molecular mechanism in Chagas’ disease cardiomyopathy. Am J Pathol. 2005;167:305-13.
    • (2005) Am J Pathol , vol.167 , pp. 305-313
    • Cunha-Neto, E.1    Dzau, V.J.2    Allen, P.D.3    Stamatiou, D.4    Benvenutti, L.5    Higuchi, M.L.6
  • 171
    • 33745199355 scopus 로고    scopus 로고
    • Cell transplantation after the coculture of skeletal myoblasts and mesenchymal stem cells in the regeneration of the myocardium scar: An experimental study in rats
    • Carvalho KA, Guarita-Souza LC, Hansen P, Rebelatto CL, Senegaglia AC, Miyague N, et al. Cell transplantation after the coculture of skeletal myoblasts and mesenchymal stem cells in the regeneration of the myocardium scar: an experimental study in rats. Transplant Proc. 2006;38:1596-602.
    • (2006) Transplant Proc , vol.38 , pp. 1596-1602
    • Carvalho, K.A.1    Guarita-Souza, L.C.2    Hansen, P.3    Rebelatto, C.L.4    Senegaglia, A.C.5    Miyague, N.6
  • 172
    • 4043109215 scopus 로고    scopus 로고
    • Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure
    • Wakisaka Y, Niwano S, Niwano H, Saito J, Yoshida T, Hirasawa S, et al. Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure. Cardiovasc Res. 2004;63: 689-99.
    • (2004) Cardiovasc Res , vol.63 , pp. 689-699
    • Wakisaka, Y.1    Niwano, S.2    Niwano, H.3    Saito, J.4    Yoshida, T.5    Hirasawa, S.6
  • 173
    • 0031022821 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in rat experimental autoimmune myocarditis with special reference to changes in cardiac hemodynamics
    • Hirono S, Islam MO, Nakazawa M, Yoshida Y, Kodama M, Shibata A, et al. Expression of inducible nitric oxide synthase in rat experimental autoimmune myocarditis with special reference to changes in cardiac hemodynamics. Circ Res. 1997;80:11-20.
    • (1997) Circ Res , vol.80 , pp. 11-20
    • Hirono, S.1    Islam, M.O.2    Nakazawa, M.3    Yoshida, Y.4    Kodama, M.5    Shibata, A.6
  • 174
    • 47549119123 scopus 로고    scopus 로고
    • Molecular diagnosis of the viral component in cardiomyopathies: Pathophysiological, clinical and therapeutic implications
    • Halapas A, Pissimissis N, Lembessis P, Rizos I, Rigopoulos AG, Kremastinos DT, et al. Molecular diagnosis of the viral component in cardiomyopathies: pathophysiological, clinical and therapeutic implications. Expert Opin Ther Targets. 2008;12:821-36.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 821-836
    • Halapas, A.1    Pissimissis, N.2    Lembessis, P.3    Rizos, I.4    Rigopoulos, A.G.5    Kremastinos, D.T.6
  • 175
    • 33750200769 scopus 로고    scopus 로고
    • Cardiac troponin i but not cardiac troponin t induces severe autoimmune inflamma-tion in the myocardium
    • Goser S, Andrassy M, Buss SJ, Leuschner F, Volz CH, Ottl R, et al. Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflamma-tion in the myocardium. Circulation. 2006; 114: 1693-702.
    • (2006) Circulation , vol.114 , pp. 1693-1702
    • Goser, S.1    Rassy, M.2    Buss, S.J.3    Leuschner, F.4    Volz, C.H.5    Ottl, R.6
  • 176
    • 33748674457 scopus 로고    scopus 로고
    • Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension
    • Usui S, Yao A, Hatano M, Kohmoto O, Takahashi T, Nagai R, et al. Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension. Circ J. 2006;70:1208-15.
    • (2006) Circ J , vol.70 , pp. 1208-1215
    • Usui, S.1    Yao, A.2    Hatano, M.3    Kohmoto, O.4    Takahashi, T.5    Nagai, R.6
  • 177
    • 0015326944 scopus 로고
    • Pulmonary oedema in rats given monocrotaline pyrrole
    • Plestina R, Stoner HB. Pulmonary oedema in rats given monocrotaline pyrrole. J Pathol. 1972;106:235-49.
    • (1972) J Pathol , vol.106 , pp. 235-249
    • Plestina, R.1    Stoner, H.B.2
  • 178
    • 0014572715 scopus 로고
    • Electron microscopy of crotalaria pulmonary hypertension
    • Kay JM, Smith P, Heath D. Electron microscopy of Crotalaria pulmonary hypertension. Thorax. 1969;24:511-26.
    • (1969) Thorax , vol.24 , pp. 511-526
    • Kay, J.M.1    Smith, P.2    Heath, D.3
  • 179
    • 84965190466 scopus 로고
    • Pathological changes in rats as a result of treatment with monocrotaline
    • Schoental R, Head MA. Pathological changes in rats as a result of treatment with monocrotaline. Br J Cancer. 1955;9:229-37.
    • (1955) Br J Cancer , vol.9 , pp. 229-237
    • Schoental, R.1    Head, M.A.2
  • 180
    • 33751168945 scopus 로고    scopus 로고
    • Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat
    • Hessel MH, Steendijk P, den Adel B, Schutte CI, van der Laarse A. Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat. Am J Physiol Heart Circ Physiol. 2006;291:H2424-30.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H2424-H2H30
    • Hessel, M.H.1    Steendijk, P.2    Den Adel, B.3    Schutte, C.I.4    Van Der Laarse, A.5
  • 181
    • 79960819370 scopus 로고    scopus 로고
    • Diastolic heart failure: Progress, treatment challenges, and prevention
    • Wood P, Piran S, Liu PP. Diastolic heart failure: progress, treatment challenges, and prevention. Can J Cardiol. 2011;27:302-10.
    • (2011) Can J Cardiol , vol.27 , pp. 302-310
    • Wood, P.1    Piran, S.2    Liu, P.P.3
  • 182
    • 77951878319 scopus 로고    scopus 로고
    • Large animal models for diastolic dysfunction and diastolic heart failure-a review of the literature
    • Dubi S, Arbel Y. Large animal models for diastolic dysfunction and diastolic heart failure-a review of the literature. Cardiovasc Pathol. 2010;19:147-52.
    • (2010) Cardiovasc Pathol , vol.19 , pp. 147-152
    • Dubi, S.1    Arbel, Y.2
  • 183
    • 0037133660 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure: Part i: Diag-nosis, prognosis, and measurements of diastolic function
    • Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: part I: diag-nosis, prognosis, and measurements of diastolic function. Circulation. 2002;105:1387-93.
    • (2002) Circulation , vol.105 , pp. 1387-1393
    • Zile, M.R.1    Brutsaert, D.L.2
  • 185
    • 0035838376 scopus 로고    scopus 로고
    • Exercise training attenuates age-associated diastolic dysfunction in rats
    • Brenner DA, Apstein CS, Saupe KW. Exercise training attenuates age-associated diastolic dysfunction in rats. Circulation. 2001;104:221-6.
    • (2001) Circulation , vol.104 , pp. 221-226
    • Brenner, D.A.1    Apstein, C.S.2    Saupe, K.W.3
  • 186
    • 0036143320 scopus 로고    scopus 로고
    • The cardiac phenotype induced by pparalpha overexpression mimics that caused by diabetes mellitus
    • Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, et al. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest. 2002;109:121-30.
    • (2002) J Clin Invest , vol.109 , pp. 121-130
    • Finck, B.N.1    Lehman, J.J.2    Leone, T.C.3    Welch, M.J.4    Bennett, M.J.5    Kovacs, A.6
  • 187
    • 0034106175 scopus 로고    scopus 로고
    • Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy
    • Huang WY, Aramburu J, Douglas PS, Izumo S. Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy. Nat Med. 2000;6:482-3.
    • (2000) Nat Med , vol.6 , pp. 482-483
    • Huang, W.Y.1    Aramburu, J.2    Douglas, P.S.3    Izumo, S.4
  • 188
    • 58149305990 scopus 로고    scopus 로고
    • With great power comes great responsibility: Using mouse genetics to study cardiac hypertrophy and failure
    • Molkentin JD, Robbins J. With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure. J Mol Cell Cardiol. 2009;46:130-6.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 130-136
    • Molkentin, J.D.1    Robbins, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.