PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractility

Circulation Research

Volumn 99, Issue 3, 2006, Pages 307-314

  Jeong, Dongtak ^a   Cha, Hyeseon ^a   Kim, Eunyoung ^a   Kang, Misuk ^a   Yang, Dong Kwon ^a   Kim, Ji Myoung ^a   Yoon, Pyoung Oh ^a   Oh, Jae Gyun ^a   Bernecker, Oliver Y ^b   Sakata, Susumu ^b   Thu, Le Thi ^c   Cui, Lei ^d   Lee, Young Hoon ^e   Kim, Do Han ^a   Woo, Sun Hee ^c   Liao, Ronglih ^d   Hajjar, Roger J ^b   Park, Woo Jin ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c Chungnam National University   (South Korea)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Chonbuk National University   (South Korea)

Author keywords

Cardiac hypertrophy; Contractility; PICOT; Protein kinase C

Indexed keywords

ADENOVIRUS VECTOR; ATRIAL NATRIURETIC FACTOR; ENDOTHELIN 1; PHENYLEPHRINE; PROTEIN KINASE C INTERACTING COUSIN OF THIOREDOXIN; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL SIZE; CONTROLLED STUDY; DRUG EFFICACY; GENE OVEREXPRESSION; HEART CONTRACTION; HEART EJECTION FRACTION; HEART FAILURE; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; MUSCLE FIBER CONTRACTION; MYOFILAMENT; NEGATIVE FEEDBACK; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SARCOMERE; SARCOPLASMIC RETICULUM; STIMULUS RESPONSE; SYSTOLIC BLOOD PRESSURE; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; CARRIER PROTEINS; CELLS, CULTURED; ENZYME INHIBITORS; GENE THERAPY; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 33746825412     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000234780.06115.2c     Document Type: Article

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