Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 3, 2011, Pages

  Reed, Alana L ^a   Tanaka, Atsuko ^a   Sorescu, Dan ^a   Liu, Hong ^b   Jeong, Euy Myoung ^b   Sturdy, Megan ^b   Walp, Erik R ^a   Dudley Jr , Samuel C ^b   Sutliff, Roy L ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Aging; Heart failure; Transforming growth factor

Indexed keywords

COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE MEASUREMENT; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DISEASE ASSOCIATION; GENE EXPRESSION; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE FIBROSIS; INTERSTITIUM; MITRAL VALVE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULSE WAVE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SARCOMERE LENGTH; SENESCENCE ACCELERATED MOUSE; TISSUE DOPPLER IMAGING; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING;

AGE FACTORS; AGING; AGING, PREMATURE; ANALYSIS OF VARIANCE; ANIMALS; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; DIASTOLE; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY, DOPPLER, PULSED; ELASTICITY; FIBROSIS; GENE EXPRESSION REGULATION; HEART CATHETERIZATION; HEART FAILURE; HEMODYNAMICS; MICE; MICE, TRANSGENIC; MYOCARDIUM; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 80052334365     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00407.2010     Document Type: Article

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