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Volumn 47, Issue 5, 2015, Pages 368-375

Parthenolide inhibits LPS-induced inflammatory cytokines through the toll-like receptor 4 signal pathway in THP-1 cells

Author keywords

anti inflammation; inflammatory cytokine; MAPK; parthenolide; TLR4

Indexed keywords

AUTACOID; CYTOKINE; LIPOPOLYSACCHARIDE; PARTHENOLIDE; SESQUITERPENE; TOLL LIKE RECEPTOR 4;

EID: 84944273170     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmv019     Document Type: Article
Times cited : (34)

References (38)
  • 1
    • 84876348441 scopus 로고    scopus 로고
    • The role of pattern recognition receptors in intestinal inflammation
    • Fukata M, Arditi M. The role of pattern recognition receptors in intestinal inflammation. Mucosal Immunol 2013, 6: 451-463.
    • (2013) Mucosal Immunol , vol.6 , pp. 451-463
    • Fukata, M.1    Arditi, M.2
  • 2
    • 84905661901 scopus 로고    scopus 로고
    • The role of patternrecognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation
    • Heidegger S, van den Brink MR, Haas T, Poeck H. The role of patternrecognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation. Front Immunol 2014, 5: 337.
    • (2014) Front Immunol , vol.5 , pp. 337
    • Heidegger, S.1    Van Den Brink, M.R.2    Haas, T.3    Poeck, H.4
  • 3
    • 84906996460 scopus 로고    scopus 로고
    • Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages
    • Zhang X, Wang G, Gurley EC, Zhou H. Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages. PLoS One 2014, 9: e107072.
    • (2014) PLoS One , vol.9 , pp. e107072
    • Zhang, X.1    Wang, G.2    Gurley, E.C.3    Zhou, H.4
  • 5
    • 84919429527 scopus 로고    scopus 로고
    • Toll-like receptors and cancer, particularly oral squamous cell carcinoma
    • Rich AM, Hussaini HM, Parachuru VP, Seymour GJ. Toll-like receptors and cancer, particularly oral squamous cell carcinoma. Front Immunol 2014, 5: 464.
    • (2014) Front Immunol , vol.5 , pp. 464
    • Rich, A.M.1    Hussaini, H.M.2    Parachuru, V.P.3    Seymour, G.J.4
  • 6
    • 84907426298 scopus 로고    scopus 로고
    • Flavonoid fraction of bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-kappaB inhibition in THP-1 monocytes
    • Risitano R, Curro M, Cirmi S, Ferlazzo N, Campiglia P, Caccamo D, Ientile R, et al. Flavonoid fraction of bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-kappaB inhibition in THP-1 monocytes. PLoS One 2014, 9: e107431.
    • (2014) PLoS One , vol.9 , pp. e107431
    • Risitano, R.1    Curro, M.2    Cirmi, S.3    Ferlazzo, N.4    Campiglia, P.5    Caccamo, D.6    Ientile, R.7
  • 7
    • 78951468918 scopus 로고    scopus 로고
    • Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells
    • Wu F, Zhang W, Li L, Zheng F, Shao X, Zhou J, Li H. Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells. Eur J Pharmacol 2011, 654: 117-121.
    • (2011) Eur J Pharmacol , vol.654 , pp. 117-121
    • Wu, F.1    Zhang, W.2    Li, L.3    Zheng, F.4    Shao, X.5    Zhou, J.6    Li, H.7
  • 8
    • 0343765810 scopus 로고    scopus 로고
    • Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB
    • Bork PM, Schmitz ML, Kuhnt M, Escher C, Heinrich M. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB. FEBS Lett 1997, 402: 85-90.
    • (1997) FEBS Lett , vol.402 , pp. 85-90
    • Bork, P.M.1    Schmitz, M.L.2    Kuhnt, M.3    Escher, C.4    Heinrich, M.5
  • 9
    • 0034664169 scopus 로고    scopus 로고
    • Inhibition by parthenolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1
    • Fukuda K, Hibiya Y, Mutoh M, Ohno Y, Yamashita K, Akao S, Fujiwara H. Inhibition by parthenolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1. Biochem Pharmacol 2000, 60: 595-600.
    • (2000) Biochem Pharmacol , vol.60 , pp. 595-600
    • Fukuda, K.1    Hibiya, Y.2    Mutoh, M.3    Ohno, Y.4    Yamashita, K.5    Akao, S.6    Fujiwara, H.7
  • 10
    • 84863269069 scopus 로고    scopus 로고
    • Parthenolide attenuates LPS-induced activation of NF-kappaB in a time-dependent manner in rat myocardium
    • Xie H,Wang C, Wu X, Liu X, Qiao S, Liu C, Liu H. Parthenolide attenuates LPS-induced activation of NF-kappaB in a time-dependent manner in rat myocardium. J Biomed Res 2012, 26: 37-43.
    • (2012) J Biomed Res , vol.26 , pp. 37-43
    • Xie, H.1    Wang, C.2    Wu, X.3    Liu, X.4    Qiao, S.5    Liu, C.6    Liu, H.7
  • 11
    • 84866070788 scopus 로고    scopus 로고
    • Parthenolide inhibits the LPS-induced secretion of IL-6 and TNF-alpha and NF-kappaB nuclear translocation in BV-2 microglia
    • Magni P, Ruscica M, Dozio E, Rizzi E, Beretta G, Maffei FR. Parthenolide inhibits the LPS-induced secretion of IL-6 and TNF-alpha and NF-kappaB nuclear translocation in BV-2 microglia. Phytother Res 2012, 26: 1405-1409.
    • (2012) Phytother Res , vol.26 , pp. 1405-1409
    • Magni, P.1    Ruscica, M.2    Dozio, E.3    Rizzi, E.4    Beretta, G.5    Maffei, F.R.6
  • 12
    • 0036848107 scopus 로고    scopus 로고
    • Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells
    • Fiebich BL, Lieb K, Engels S, Heinrich M. Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells. J Neuroimmunol 2002, 132: 18-24.
    • (2002) J Neuroimmunol , vol.132 , pp. 18-24
    • Fiebich, B.L.1    Lieb, K.2    Engels, S.3    Heinrich, M.4
  • 13
    • 79959989475 scopus 로고    scopus 로고
    • Parthenolide inhibits TRIF-dependent signaling pathway of toll-like receptors in RAW264
    • Park SJ, Shin HJ, Youn HS. Parthenolide inhibits TRIF-dependent signaling pathway of toll-like receptors in RAW264.7 macrophages. Mol Cells 2011, 31: 261-265.
    • (2011) 7 Macrophages. Mol Cells , vol.31 , pp. 261-265
    • Park, S.J.1    Shin, H.J.2    Youn, H.S.3
  • 14
    • 84964292216 scopus 로고    scopus 로고
    • Chikusetsusaponin v inhibits inflammatory responses via NF-kappaB and MAPK signaling pathways in LPS-induced RAW 264
    • Wang T, Dai Y, Dun Y, Zhang C, Wan J, Deng L, Zhou Z, et al. Chikusetsusaponin V inhibits inflammatory responses via NF-kappaB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages. Immunopharmacol Immunotoxicol 2014, 0: 1-8.
    • (2014) 7 Macrophages. Immunopharmacol Immunotoxicol , vol.0 , pp. 1-8
    • Wang, T.1    Dai, Y.2    Dun, Y.3    Zhang, C.4    Wan, J.5    Deng, L.6    Zhou, Z.7
  • 15
    • 84924370896 scopus 로고    scopus 로고
    • Distinct contribution of PKCdelta and PKCepsilon in the lifespan and immune response of human blood monocyte subpopulations
    • Malavez Y, Voss OH, Gonzalez-Mejia ME, Parihar A, Doseff AI. Distinct contribution of PKCdelta and PKCepsilon in the lifespan and immune response of human blood monocyte subpopulations. Immunology 2015, 144: 611-620.
    • (2015) Immunology , vol.144 , pp. 611-620
    • Malavez, Y.1    Voss, O.H.2    Gonzalez-Mejia, M.E.3    Parihar, A.4    Doseff, A.I.5
  • 16
    • 84878894469 scopus 로고    scopus 로고
    • Expression of ALDH1 in breast invasive ductal carcinoma: An independent predictor of early tumor relapse
    • Zhong Y, Lin Y, Shen S, Zhou Y, Mao F, Guan J, Sun Q. Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse. Cancer Cell Int 2013, 13: 60.
    • (2013) Cancer Cell Int , vol.13 , pp. 60
    • Zhong, Y.1    Lin, Y.2    Shen, S.3    Zhou, Y.4    Mao, F.5    Guan, J.6    Sun, Q.7
  • 17
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 6344267090 scopus 로고    scopus 로고
    • Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through toll-like receptor 4 and NF-kappaB
    • Prince LS, Okoh VO, Moninger TO, Matalon S. Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through toll-like receptor 4 and NF-kappaB. Am J Physiol Lung Cell Mol Physiol 2004, 287: L999-L1006.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , pp. L999-L1006
    • Prince, L.S.1    Okoh, V.O.2    Moninger, T.O.3    Matalon, S.4
  • 19
    • 84918811053 scopus 로고    scopus 로고
    • Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-kappaB pathway
    • Zhao W, Ma G, Chen X. Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-kappaB pathway. Vascul Pharmacol 2014, 63: 162-172.
    • (2014) Vascul Pharmacol , vol.63 , pp. 162-172
    • Zhao, W.1    Ma, G.2    Chen, X.3
  • 20
    • 84878627998 scopus 로고    scopus 로고
    • Zn(II)-chlorido complexes of phytohormone kinetin and its derivatives modulate expression of inflammatory mediators in THP-1 cells
    • Hosek J, Novotna R, Babula P, Vanco J, Travnicek Z. Zn(II)-chlorido complexes of phytohormone kinetin and its derivatives modulate expression of inflammatory mediators in THP-1 cells. PLoS One 2013, 8: e65214.
    • (2013) PLoS One , vol.8 , pp. e65214
    • Hosek, J.1    Novotna, R.2    Babula, P.3    Vanco, J.4    Travnicek, Z.5
  • 21
    • 78650967552 scopus 로고    scopus 로고
    • Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts
    • Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, et al. Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts. Korean J Intern Med 2010, 25: 429-435.
    • (2010) Korean J Intern Med , vol.25 , pp. 429-435
    • Moon, S.J.1    Park, M.K.2    Oh, H.J.3    Lee, S.Y.4    Kwok, S.K.5    Cho, M.L.6    Ju, J.H.7
  • 22
    • 33847680512 scopus 로고    scopus 로고
    • Toll-like receptor 2 and 4 combination engagement upregulate IL-15 synergistically in human rheumatoid synovial fibroblasts
    • Jung YO, Cho ML, Kang CM, Jhun JY, Park JS, Oh HJ, Min JK, et al. Toll-like receptor 2 and 4 combination engagement upregulate IL-15 synergistically in human rheumatoid synovial fibroblasts. Immunol Lett 2007, 109: 21-27.
    • (2007) Immunol Lett , vol.109 , pp. 21-27
    • Jung, Y.O.1    Cho, M.L.2    Kang, C.M.3    Jhun, J.Y.4    Park, J.S.5    Oh, H.J.6    Min, J.K.7
  • 23
    • 0034879173 scopus 로고    scopus 로고
    • The antiinflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase
    • Kwok BH, Koh B, Ndubuisi MI, Elofsson M, Crews CM. The antiinflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol 2001, 8: 759-766.
    • (2001) Chem Biol , vol.8 , pp. 759-766
    • Kwok, B.H.1    Koh, B.2    Ndubuisi, M.I.3    Elofsson, M.4    Crews, C.M.5
  • 24
    • 84889666343 scopus 로고    scopus 로고
    • Palmitate induces interleukin-8 expression in human aortic vascular smooth muscle cells via toll-like receptor 4/nuclear factor-kappaB pathway (TLR4/NF-kappaB-8)
    • Quan J, Liu J, Gao X, Liu J, Yang H, ChenW, LiW, et al. Palmitate induces interleukin-8 expression in human aortic vascular smooth muscle cells via toll-like receptor 4/nuclear factor-kappaB pathway (TLR4/NF-kappaB-8). J Diabetes 2014, 6: 33-41.
    • (2014) J Diabetes , vol.6 , pp. 33-41
    • Quan, J.1    Liu, J.2    Gao, X.3    Liu, J.4    Yang, H.5    Chen, W.6    Li, W.7
  • 25
    • 0035797147 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: Involvement of nuclear factor-kappaB
    • Kang BY, Chung SW, Kim TS. Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kappaB. Immunol Lett 2001, 77: 159-163.
    • (2001) Immunol Lett , vol.77 , pp. 159-163
    • Kang, B.Y.1    Chung, S.W.2    Kim, T.S.3
  • 26
    • 84874442640 scopus 로고    scopus 로고
    • Enhanced IL-12p40 production in LPS-stimulated macrophages by inhibiting JNK activation by artemisinin
    • Cho YC, Lee SH, Lee M, Kim HJ, Oak MH, Lee IS, Kang BY. Enhanced IL-12p40 production in LPS-stimulated macrophages by inhibiting JNK activation by artemisinin. Arch Pharm Res 2012, 35: 1961-1968.
    • (2012) Arch Pharm Res , vol.35 , pp. 1961-1968
    • Cho, Y.C.1    Lee, S.H.2    Lee, M.3    Kim, H.J.4    Oak, M.H.5    Lee, I.S.6    Kang, B.Y.7
  • 27
    • 84906940039 scopus 로고    scopus 로고
    • A heteroglycan from the cyanobacterium Nostoc commune modulates LPS-induced inflammatory cytokine secretion by THP-1 monocytes through phosphorylation of ERK1/2 and Akt
    • Olafsdottir A, Thorlacius GE, Omarsdottir S, Olafsdottir ES, Vikingsson A, Freysdottir J, Hardardottir I. A heteroglycan from the cyanobacterium Nostoc commune modulates LPS-induced inflammatory cytokine secretion by THP-1 monocytes through phosphorylation of ERK1/2 and Akt. Phytomedicine 2014, 21: 1451-1457.
    • (2014) Phytomedicine , vol.21 , pp. 1451-1457
    • Olafsdottir, A.1    Thorlacius, G.E.2    Omarsdottir, S.3    Olafsdottir, E.S.4    Vikingsson, A.5    Freysdottir, J.6    Hardardottir, I.7
  • 28
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005, 17: 1-14.
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 29
    • 65349113645 scopus 로고    scopus 로고
    • Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/ p38MAPK pathways in RAW264. 7 macrophages
    • PangHY, Liu G, Liu GT. Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/ p38MAPK pathways in RAW264.7 macrophages. Acta Pharmacol Sin 2009, 30: 209-218.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 209-218
    • Pang, H.Y.1    Liu, G.2    Liu, G.T.3
  • 30
    • 38449100478 scopus 로고    scopus 로고
    • Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes
    • Madhavan S, Anghelina M, Sjostrom D, Dossumbekova A, Guttridge DC, Agarwal S. Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes. J Immunol 2007, 179: 6246-6254.
    • (2007) J Immunol , vol.179 , pp. 6246-6254
    • Madhavan, S.1    Anghelina, M.2    Sjostrom, D.3    Dossumbekova, A.4    Guttridge, D.C.5    Agarwal, S.6
  • 31
    • 84866990008 scopus 로고    scopus 로고
    • Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-kappaB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264. 7 cells
    • Chun J, Choi RJ, Khan S, Lee DS, Kim YC, Nam YJ, Lee DU, et al. Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-kappaB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells. Int Immunopharmacol 2012, 14: 375-383.
    • (2012) Int Immunopharmacol , vol.14 , pp. 375-383
    • Chun, J.1    Choi, R.J.2    Khan, S.3    Lee, D.S.4    Kim, Y.C.5    Nam, Y.J.6    Lee, D.U.7
  • 32
    • 78649347028 scopus 로고    scopus 로고
    • Inflammation and immunity in the tumor environment
    • Maletzki C, Emmrich J. Inflammation and immunity in the tumor environment. Digest Dis 2010, 28: 574-578.
    • (2010) Digest Dis , vol.28 , pp. 574-578
    • Maletzki, C.1    Emmrich, J.2
  • 33
    • 84863296678 scopus 로고    scopus 로고
    • Inflammation: What role in pediatric cancer?
    • Morgenstern DA, Anderson J. Inflammation: what role in pediatric cancer? Pediatr Blood Cancer 2012, 58: 659-664.
    • (2012) Pediatr Blood Cancer , vol.58 , pp. 659-664
    • Morgenstern, D.A.1    Anderson, J.2
  • 34
    • 84865967712 scopus 로고    scopus 로고
    • Sesquiterpene lactones as drugs with multiple targets in cancer treatment: Focus on parthenolide
    • Kreuger MR, Grootjans S, Biavatti MW, Vandenabeele P, D'Herde K. Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide. Anticancer Drugs 2012, 23: 883-896.
    • (2012) Anticancer Drugs , vol.23 , pp. 883-896
    • Kreuger, M.R.1    Grootjans, S.2    Biavatti, M.W.3    Vandenabeele, P.4    D'herde, K.5
  • 35
    • 70349289739 scopus 로고    scopus 로고
    • Nuclear factor-kappaB signaling: A contributor in leukemogenesis and a target for pharmacological intervention in human acute myelogenous leukemia
    • Reikvam H, Olsnes AM, Gjertsen BT, Ersvar E, Bruserud O. Nuclear factor-kappaB signaling: a contributor in leukemogenesis and a target for pharmacological intervention in human acute myelogenous leukemia. Crit Rev Oncog 2009, 15: 1-41.
    • (2009) Crit Rev Oncog , vol.15 , pp. 1-41
    • Reikvam, H.1    Olsnes, A.M.2    Gjertsen, B.T.3    Ersvar, E.4    Bruserud, O.5
  • 36
    • 16844363378 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
    • Guzman ML. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 2005, 105: 4163-4169.
    • (2005) Blood , vol.105 , pp. 4163-4169
    • Guzman, M.L.1
  • 37
    • 84914127486 scopus 로고    scopus 로고
    • Changes of sulfur dioxide, nuclear factor-kappaB, and interleukin-8 levels in pediatric acute lymphoblastic leukemia with bacterial inflammation
    • WuW, Jia Y, Du S, Tang H, Sun Y, Sun L. Changes of sulfur dioxide, nuclear factor-kappaB, and interleukin-8 levels in pediatric acute lymphoblastic leukemia with bacterial inflammation. Chin Med J 2014, 127: 4110-4113.
    • (2014) Chin Med J , vol.127 , pp. 4110-4113
    • Wu, W.1    Jia, Y.2    Du, S.3    Tang, H.4    Sun, Y.5    Sun, L.6
  • 38
    • 33744480255 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro
    • Steele AJ, Jones DT, Ganeshaguru K, Duke VM, Yogashangary BC, North JM, Lowdell MW, et al. The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro. Leukemia 2006, 20: 1073-1079.
    • (2006) Leukemia , vol.20 , pp. 1073-1079
    • Steele, A.J.1    Jones, D.T.2    Ganeshaguru, K.3    Duke, V.M.4    Yogashangary, B.C.5    North, J.M.6    Lowdell, M.W.7


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