Inhibition by parthenolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1

Biochemical Pharmacology

Volumn 60, Issue 4, 2000, Pages 595-600

  Fukuda, Kazunori ^a   Hibiya, Yuko ^b   Mutoh, Michihiro ^b   Ohno, Yasushi ^a   Yamashita, Kazuya ^a   Akao, Seigou ^a   Fujiwara, Hisayoshi ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

12 O tetradecanoylphorbol 13 acetate; Luciferase; Nitric oxide synthase; Parthenolide; THP 1 cells; Transcriptional activity

Indexed keywords

LUCIFERASE; NITRIC OXIDE SYNTHASE; PARTHENOLIDE; PHORBOL 13 ACETATE 12 MYRISTATE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; GENE ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IC 50; MONOCYTE; PRIORITY JOURNAL; REPORTER GENE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; DRUG INTERACTIONS; HUMANS; MONOCYTES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; SESQUITERPENES; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATION (GENETICS);

EID: 0034664169     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00340-3     Document Type: Article

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