Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage

Autophagy

Volumn 11, Issue 7, 2015, Pages 1099-1113

  Filippi Chiela, Eduardo Cremonese ^a   Silva, Mardja Manssur Bueno ^a   Thomé, Marcos Paulo ^a   Lenz, Guido ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Autophagy; DNA damage; Senescence; Single cell; Temozolomide

Indexed keywords

BIOLOGICAL MARKER; DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE AMP ACTIVATED PROTEIN; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; TEMOZOLOMIDE; ULK1 PROTEIN; UNCLASSIFIED DRUG; DACARBAZINE; GREEN FLUORESCENT PROTEIN; SERINE THREONINE PROTEIN KINASE ULK1; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; ULK1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL AGING; CONTROLLED STUDY; DNA DAMAGE; ENZYME INHIBITION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SINGLE CELL ANALYSIS; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; CELL CYCLE CHECKPOINT; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GLIOMA; METABOLISM; PATHOLOGY; PHENOTYPE; PROCEDURES; TIME FACTOR; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN-1 HOMOLOG; CELL AGING; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DACARBAZINE; DNA DAMAGE; ENZYME ACTIVATION; GLIOMA; GREEN FLUORESCENT PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; SINGLE-CELL ANALYSIS; SIROLIMUS; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84943778489     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1009795     Document Type: Article

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