-
1
-
-
39849083763
-
Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death
-
DOI 10.1038/sj.mt.6300400, PII 6300400
-
Alonso MM, Jiang H, Yokoyama T, Xu J, Bekele NB, Lang FF, et al, (2008) Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death. Mol Ther 16: 487-493. (Pubitemid 351314987)
-
(2008)
Molecular Therapy
, vol.16
, Issue.3
, pp. 487-493
-
-
Alonso, M.M.1
Jiang, H.2
Yokoyama, T.3
Xu, J.4
Bekele, N.B.5
Lang, F.F.6
Kondo, S.7
Gomez-Manzano, C.8
Fueyo, J.9
-
2
-
-
43949106884
-
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3
-
Aoki H, Kondo Y, Aldape K, Yamamoto A, Iwado E, Yokoyama T, et al, (2008) Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3. Autophagy 4: 467-475. (Pubitemid 351705143)
-
(2008)
Autophagy
, vol.4
, Issue.4
, pp. 467-475
-
-
Aoki, H.1
Kondo, Y.2
Aldape, K.3
Yamamoto, A.4
Iwado, E.5
Yokoyama, T.6
Hollingsworth, E.F.7
Kobayashi, R.8
Hess, K.9
Shinojima, N.10
Shingu, T.11
Tamada, Y.12
Zhang, L.13
Conrad, C.14
Bogler, O.15
Mills, G.16
Sawaya, R.17
Kondo, S.18
-
3
-
-
0035929650
-
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
-
Arico S, Petiot A, Bauvy C, Dubbelhuis PF, Meijer AJ, Codogno P, Ogier-Denis E, (2001) The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 276: 35243-35246.
-
(2001)
J Biol Chem
, vol.276
, pp. 35243-35246
-
-
Arico, S.1
Petiot, A.2
Bauvy, C.3
Dubbelhuis, P.F.4
Meijer, A.J.5
Codogno, P.6
Ogier-Denis, E.7
-
4
-
-
66349121718
-
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
-
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssegur J, Mazure NM, (2009) Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 29: 2570-2581.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouyssegur, J.6
Mazure, N.M.7
-
5
-
-
79955959364
-
Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines
-
Carrasco-Garcia E, Saceda M, Grasso S, Rocamora-Reverte L, Conde M, Gomez-Martinez A, et al, (2011) Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines. Exp Cell Res 317: 1476-1489.
-
(2011)
Exp Cell Res
, vol.317
, pp. 1476-1489
-
-
Carrasco-Garcia, E.1
Saceda, M.2
Grasso, S.3
Rocamora-Reverte, L.4
Conde, M.5
Gomez-Martinez, A.6
-
7
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
DOI 10.1007/s10637-005-1444-0
-
Chang SM, Wen P, Cloughesy T, Greenberg H, Schiff D, Conrad C, et al, (2005) Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. Invest New Drugs 23: 357-361. (Pubitemid 40980358)
-
(2005)
Investigational New Drugs
, vol.23
, Issue.4
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
Greenberg, H.4
Schiff, D.5
Conrad, C.6
Fink, K.7
Robins, H.I.8
De Angelis, L.9
Raizer, J.10
Hess, K.11
Aldape, K.12
Lamborn, K.R.13
Kuhn, J.14
Dancey, J.15
Prados, M.D.16
-
8
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
Chen N, Karantza V, (2011) Autophagy as a therapeutic target in cancer. Cancer Biol Ther 11: 157-168.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 157-168
-
-
Chen, N.1
Karantza, V.2
-
9
-
-
57449104947
-
PI3K signaling in glioma-animal models and therapeutic challenges
-
Cheng CK, Fan QW, Weiss WA, (2009) PI3K signaling in glioma-animal models and therapeutic challenges. Brain Pathol 19: 112-120.
-
(2009)
Brain Pathol
, vol.19
, pp. 112-120
-
-
Cheng, C.K.1
Fan, Q.W.2
Weiss, W.A.3
-
10
-
-
66349090851
-
Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways
-
Chiu HW, Ho SY, Guo HR, Wang YJ, (2009) Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways. Autophagy 5: 472-483.
-
(2009)
Autophagy
, vol.5
, pp. 472-483
-
-
Chiu, H.W.1
Ho, S.Y.2
Guo, H.R.3
Wang, Y.J.4
-
11
-
-
33745885329
-
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
-
DOI 10.1016/j.cell.2006.05.034, PII S0092867406007598
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, et al, (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126: 121-134. (Pubitemid 44040988)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
12
-
-
3042562282
-
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells
-
DOI 10.1158/0008-5472.CAN-03-3084
-
Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y, Kondo S, (2004) Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. Cancer Res 64: 4286-4293. (Pubitemid 38802435)
-
(2004)
Cancer Research
, vol.64
, Issue.12
, pp. 4286-4293
-
-
Daido, S.1
Kanzawa, T.2
Yamamoto, A.3
Takeuchi, H.4
Kondo, Y.5
Kondo, S.6
-
13
-
-
20144373772
-
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy
-
DOI 10.1158/0008-5472.CAN-04-4202
-
Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, Kondo Y, (2005) Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res 65: 4368-4375. (Pubitemid 40775676)
-
(2005)
Cancer Research
, vol.65
, Issue.10
, pp. 4368-4375
-
-
Daido, S.1
Yamamoto, A.2
Fujiwara, K.3
Sawaya, R.4
Kondo, S.5
Kondo, Y.6
-
15
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, et al, (2006) Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10: 51-64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
-
16
-
-
53749104349
-
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
-
Degtyarev M, De Maziere A, Orr C, Lin J, Lee BB, Tien JY, et al, (2008) Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol 183: 101-116.
-
(2008)
J Cell Biol
, vol.183
, pp. 101-116
-
-
Degtyarev, M.1
De Maziere, A.2
Orr, C.3
Lin, J.4
Lee, B.B.5
Tien, J.Y.6
-
17
-
-
79958826703
-
Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death
-
Eimer S, Belaud-Rotureau MA, Airiau K, Jeanneteau M, Laharanne E, Veron N, et al, (2011) Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death. Cancer Biol Ther 11: 1017-1027.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 1017-1027
-
-
Eimer, S.1
Belaud-Rotureau, M.A.2
Airiau, K.3
Jeanneteau, M.4
Laharanne, E.5
Veron, N.6
-
18
-
-
33646382364
-
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
-
DOI 10.1016/j.ccr.2006.03.029, PII S1535610806001164
-
Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, et al, (2006) A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell 9: 341-349. (Pubitemid 43668732)
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 341-349
-
-
Fan, Q.-W.1
Knight, Z.A.2
Goldenberg, D.D.3
Yu, W.4
Mostov, K.E.5
Stokoe, D.6
Shokat, K.M.7
Weiss, W.A.8
-
19
-
-
34548596728
-
A dual phosphoinositide-3-kinase α/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma
-
DOI 10.1158/0008-5472.CAN-07-2154
-
Fan QW, Cheng CK, Nicolaides TP, Hackett CS, Knight ZA, Shokat KM, Weiss WA, (2007) A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Res 67: 7960-7965. (Pubitemid 47395125)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 7960-7965
-
-
Fan, Q.-W.1
Cheng, C.K.2
Nicolaides, T.P.3
Hackett, C.S.4
Knight, Z.A.5
Shokat, K.M.6
Weiss, W.A.7
-
20
-
-
78149475478
-
Akt and autophagy cooperate to promote survival of drug-resistant glioma
-
Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, et al, (2010) Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal 3: ra81.
-
(2010)
Sci Signal
, vol.3
-
-
Fan, Q.W.1
Cheng, C.2
Hackett, C.3
Feldman, M.4
Houseman, B.T.5
Nicolaides, T.6
-
21
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
DOI 10.1073/pnas.0502857102
-
Feng Z, Zhang H, Levine AJ, Jin S, (2005) The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci USA 102: 8204-8209. (Pubitemid 40800067)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.23
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
22
-
-
34248194200
-
The regulation of AMPK β1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
-
DOI 10.1158/0008-5472.CAN-06-4149
-
Feng Z, Hu W, de Stanchina E, Teresky AK, Jin S, Lowe S, Levine AJ, (2007) The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res 67: 3043-3053. (Pubitemid 46724841)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3043-3053
-
-
Feng, Z.1
Hu, W.2
De Stanchina, E.3
Teresky, A.K.4
Jin, S.5
Lowe, S.6
Levine, A.J.7
-
23
-
-
34347344990
-
Ambra1 regulates autophagy and development of the nervous system
-
DOI 10.1038/nature05925, PII NATURE05925
-
Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, et al, (2007) Ambra1 regulates autophagy and development of the nervous system. Nature 447: 1121-1125. (Pubitemid 47014434)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1121-1125
-
-
Maria Fimia, G.1
Stoykova, A.2
Romagnoli, A.3
Giunta, L.4
Di Bartolomeo, S.5
Nardacci, R.6
Corazzari, M.7
Fuoco, C.8
Ucar, A.9
Schwartz, P.10
Gruss, P.11
Piacentini, M.12
Chowdhury, K.13
Cecconi, F.14
-
24
-
-
34247218483
-
Gefitinib in patients with progressive high-grade gliomas: A multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
-
DOI 10.1038/sj.bjc.6603669, PII 6603669
-
Franceschi E, Cavallo G, Lonardi S, Magrini E, Tosoni A, Grosso D, et al, (2007) Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). Br J Cancer 96: 1047-1051. (Pubitemid 46608313)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.7
, pp. 1047-1051
-
-
Franceschi, E.1
Cavallo, G.2
Lonardi, S.3
Magrini, E.4
Tosoni, A.5
Grosso, D.6
Scopece, L.7
Blatt, V.8
Urbini, B.9
Pession, A.10
Tallini, G.11
Crino, L.12
Brandes, A.A.13
-
25
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T, (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 19: 2092-2100.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
26
-
-
41449109334
-
Induction of autophagy during extracellular matrix detachment promotes cell survival
-
DOI 10.1091/mbc.E07-10-1092
-
Fung C, Lock R, Gao S, Salas E, Debnath J, (2008) Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell 19: 797-806. (Pubitemid 351481798)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.3
, pp. 797-806
-
-
Fung, C.1
Lock, R.2
Gao, S.3
Salas, E.4
Debnath, J.5
-
27
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A north central cancer treatment group study
-
DOI 10.1200/JCO.2005.23.622
-
Galanis E, Buckner JC, Maurer MJ, Kreisberg JI, Ballman K, Boni J, et al, (2005) Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. J Clin Oncol 23: 5294-5304. (Pubitemid 46206983)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
Kreisberg, J.I.4
Ballman, K.5
Boni, J.6
Peralba, J.M.7
Jenkins, R.B.8
Dakhil, S.R.9
Morton, R.F.10
Jaeckle, K.A.11
Scheithauer, B.W.12
Dancey, J.13
Hidalgo, M.14
Walsh, D.J.15
-
28
-
-
67651146579
-
Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells
-
Ge PF, Zhang JZ, Wang XF, Meng FK, Li WC, Luan YX, et al, (2009) Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells. Acta Pharmacol Sin 30: 1046-1052.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 1046-1052
-
-
Ge, P.F.1
Zhang, J.Z.2
Wang, X.F.3
Meng, F.K.4
Li, W.C.5
Luan, Y.X.6
-
29
-
-
77954739712
-
Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
-
Geng Y, Kohli L, Klocke BJ, Roth KA, (2010) Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro-oncol 12: 473-481.
-
(2010)
Neuro-oncol
, vol.12
, pp. 473-481
-
-
Geng, Y.1
Kohli, L.2
Klocke, B.J.3
Roth, K.A.4
-
30
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, et al, (2011) Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev 25: 460-470.
-
(2011)
Genes Dev
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
-
31
-
-
38049098543
-
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
-
Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, et al, (2007) The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 282: 37298-37302.
-
(2007)
J Biol Chem
, vol.282
, pp. 37298-37302
-
-
Hanada, T.1
Noda, N.N.2
Satomi, Y.3
Ichimura, Y.4
Fujioka, Y.5
Takao, T.6
-
32
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA, (2000) The hallmarks of cancer. Cell 100: 57-70. (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
33
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He C, Klionsky DJ, (2009) Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 43: 67-93.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
34
-
-
79956078123
-
The dual PI3K/mTOR inhibitor BEZ235 is effective in lung cancer cell lines
-
Herrera VA, Zeindl-Eberhart E, Jung A, Huber RM, Bergner A, (2011) The dual PI3K/mTOR inhibitor BEZ235 is effective in lung cancer cell lines. Anticancer Res 31: 849-854.
-
(2011)
Anticancer Res
, vol.31
, pp. 849-854
-
-
Herrera, V.A.1
Zeindl-Eberhart, E.2
Jung, A.3
Huber, R.M.4
Bergner, A.5
-
35
-
-
48249153478
-
BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells
-
Hetschko H, Voss V, Senft C, Seifert V, Prehn JH, Kogel D, (2008) BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia 10: 873-885.
-
(2008)
Neoplasia
, vol.10
, pp. 873-885
-
-
Hetschko, H.1
Voss, V.2
Senft, C.3
Seifert, V.4
Prehn, J.H.5
Kogel, D.6
-
36
-
-
78049460392
-
Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors
-
Huang X, Bai HM, Chen L, Li B, Lu YC, (2010) Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors. J Clin Neurosci 17: 1515-1519.
-
(2010)
J Clin Neurosci
, vol.17
, pp. 1515-1519
-
-
Huang, X.1
Bai, H.M.2
Chen, L.3
Li, B.4
Lu, Y.C.5
-
37
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
-
Itakura E, Kishi C, Inoue K, Mizushima N, (2008) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 19: 5360-5372.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
38
-
-
21444442926
-
Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
-
Ito H, Daido S, Kanzawa T, Kondo S, Kondo Y, (2005) Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells. Int J Oncol 26: 1401-1410.
-
(2005)
Int J Oncol
, vol.26
, pp. 1401-1410
-
-
Ito, H.1
Daido, S.2
Kanzawa, T.3
Kondo, S.4
Kondo, Y.5
-
39
-
-
33646462468
-
Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus
-
DOI 10.1093/jnci/djj161
-
Ito H, Aoki H, Kuhnel F, Kondo Y, Kubicka S, Wirth T, et al, (2006) Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus. J Natl Cancer Inst 98: 625-636. (Pubitemid 43904846)
-
(2006)
Journal of the National Cancer Institute
, vol.98
, Issue.9
, pp. 625-636
-
-
Ito, H.1
Aoki, H.2
Kuhnel, F.3
Kondo, Y.4
Kubicka, S.5
Wirth, T.6
Iwado, E.7
Iwamaru, A.8
Fujiwara, K.9
Hess, K.R.10
Lang, F.F.11
Sawaya, R.12
Kondo, S.13
-
40
-
-
34748880650
-
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: Role of autophagic cell death
-
DOI 10.1093/jnci/djm102
-
Jiang H, Gomez-Manzano C, Aoki H, Alonso MM, Kondo S, McCormick F, et al, (2007) Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J Natl Cancer Inst 99: 1410-1414. (Pubitemid 351767180)
-
(2007)
Journal of the National Cancer Institute
, vol.99
, Issue.18
, pp. 1410-1414
-
-
Jiang, H.1
Gomez-Manzano, C.2
Aoki, H.3
Alonso, M.M.4
Kondo, S.5
McCormick, F.6
Xu, J.7
Kondo, Y.8
Bekele, B.N.9
Colman, H.10
Lang, F.F.11
Fueyo, J.12
-
42
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
DOI 10.1016/S0092-8674(02)00625-6
-
Johnstone RW, Ruefli AA, Lowe SW, (2002) Apoptosis: a link between cancer genetics and chemotherapy. Cell 108: 153-164. (Pubitemid 34161136)
-
(2002)
Cell
, vol.108
, Issue.2
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
43
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y, (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150: 1507-1513.
-
(2000)
J Cell Biol
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
44
-
-
70350097409
-
Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy
-
Kang KB, Zhu C, Yong SK, Gao Q, Wong MC, (2009) Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy. Mol Cancer 8: 66.
-
(2009)
Mol Cancer
, vol.8
, pp. 66
-
-
Kang, K.B.1
Zhu, C.2
Yong, S.K.3
Gao, Q.4
Wong, M.C.5
-
45
-
-
64549101639
-
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
-
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, et al, (2009) Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 217: 702-706.
-
(2009)
J Pathol
, vol.217
, pp. 702-706
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
Kim, Y.R.4
Song, S.Y.5
Kim, S.S.6
-
46
-
-
1842865745
-
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
-
DOI 10.1038/sj.cdd.4401359
-
Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, Kondo S, (2004) Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 11: 448-457. (Pubitemid 38489422)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 448-457
-
-
Kanzawa, T.1
Germano, I.M.2
Komata, T.3
Ito, H.4
Kondo, Y.5
Kondo, S.6
-
47
-
-
13944256602
-
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
-
DOI 10.1038/sj.onc.1208095
-
Kanzawa T, Zhang L, Xiao L, Germano IM, Kondo Y, Kondo S, (2005) Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. Oncogene 14: 980-991. (Pubitemid 40313875)
-
(2005)
Oncogene
, vol.24
, Issue.6
, pp. 980-991
-
-
Kanzawa, T.1
Zhang, L.2
Xiao, L.3
Germano, I.M.4
Kondo, Y.5
Kondo, S.6
-
48
-
-
33847008972
-
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
-
Katayama M, Kawaguchi T, Berger MS, Pieper RO, (2007) DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ 14: 548-558.
-
(2007)
Cell Death Differ
, vol.14
, pp. 548-558
-
-
Katayama, M.1
Kawaguchi, T.2
Berger, M.S.3
Pieper, R.O.4
-
49
-
-
34447132925
-
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells
-
DOI 10.1158/0008-5472.CAN-06-4217
-
Kim EH, Sohn S, Kwon HJ, Kim SU, Kim MJ, Lee SJ, Choi KS, (2007) Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res 67: 6314-6324. (Pubitemid 47037514)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 6314-6324
-
-
Eun, H.K.1
Sohn, S.2
Hyuk, J.K.3
Kim, S.U.4
Kim, M.-J.5
Lee, S.-J.6
Kyeong, S.C.7
-
50
-
-
45049083880
-
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
-
Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ, (2008) Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 39: 1059-1063.
-
(2008)
Hum Pathol
, vol.39
, pp. 1059-1063
-
-
Kim, M.S.1
Jeong, E.G.2
Ahn, C.H.3
Kim, S.S.4
Lee, S.H.5
Yoo, N.J.6
-
51
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
DOI 10.1242/jcs.01620
-
Klionsky DJ, (2005) The molecular machinery of autophagy: unanswered questions. J Cell Sci 118 (Pt 1): 7-18. (Pubitemid 40277100)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.1
, pp. 7-18
-
-
Klionsky, D.J.1
-
52
-
-
33747592333
-
Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas
-
DOI 10.1080/00313020600820880, PII H238657212562Q25
-
Lee JW, Jeong EG, Soung YH, Nam SW, Lee JY, Yoo NJ, Lee SH, (2006) Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology 38: 312-315. (Pubitemid 44266628)
-
(2006)
Pathology
, vol.38
, Issue.4
, pp. 312-315
-
-
Lee, J.W.1
Jeong, E.G.2
Soung, Y.H.3
Nam, S.W.4
Lee, J.Y.5
Yoo, N.J.6
Lee, S.H.7
-
53
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU, (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8: 688-699.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
Jung, J.U.7
-
54
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B, (1999) Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672-676. (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
55
-
-
78751511180
-
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
-
Lock R, Roy S, Kenific CM, Su JS, Salas E, Ronen SM, Debnath J, (2011) Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol Biol Cell 22: 165-178.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 165-178
-
-
Lock, R.1
Roy, S.2
Kenific, C.M.3
Su, J.S.4
Salas, E.5
Ronen, S.M.6
Debnath, J.7
-
56
-
-
67650095390
-
The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells
-
Lomonaco SL, Finniss S, Xiang C, Decarvalho A, Umansky F, Kalkanis SN, et al, (2009) The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells. Int J Cancer 125: 717-722.
-
(2009)
Int J Cancer
, vol.125
, pp. 717-722
-
-
Lomonaco, S.L.1
Finniss, S.2
Xiang, C.3
Decarvalho, A.4
Umansky, F.5
Kalkanis, S.N.6
-
57
-
-
34248998801
-
L and a BH3-like domain in Beclin-1
-
DOI 10.1038/sj.emboj.7601689, PII 7601689
-
Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, et al, (2007) Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26: 2527-2539. (Pubitemid 46788315)
-
(2007)
EMBO Journal
, vol.26
, Issue.10
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.-C.4
Gautier, F.5
Juin, P.6
Tasdemir, E.7
Pierron, G.8
Troulinaki, K.9
Tavernarakis, N.10
Hickman, J.A.11
Geneste, O.12
Kroemer, G.13
-
58
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
DOI 10.1074/jbc.M701194200
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C, (2007) Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 282: 18573-18583. (Pubitemid 47100226)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
59
-
-
78349266054
-
The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox
-
Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, et al, (2010) The autophagic tumor stroma model of cancer or "battery-operated tumor growth": a simple solution to the autophagy paradox. Cell Cycle 09: 4297-4306.
-
(2010)
Cell Cycle
, vol.9
, pp. 4297-4306
-
-
Martinez-Outschoorn, U.E.1
Whitaker-Menezes, D.2
Pavlides, S.3
Chiavarina, B.4
Bonuccelli, G.5
Casey, T.6
-
60
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
DOI 10.1101/gad.1545107
-
Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K, et al, (2007) Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 21: 1367-1381. (Pubitemid 46871040)
-
(2007)
Genes and Development
, vol.21
, Issue.11
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
Chen, G.7
Jin, S.8
White, E.9
-
61
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, et al, (2009) Autophagy suppresses tumorigenesis through elimination of p62. Cell 137: 1062-1075.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
-
62
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, et al, (2009) Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol 11: 385-396.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
-
63
-
-
33846852882
-
PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors
-
DOI 10.1158/1078-0432.CCR-06-1992
-
Mellinghoff IK, Cloughesy TF, Mischel PS, (2007) PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors. Clin Cancer Res 13: 378-381. (Pubitemid 46225339)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.2
, pp. 378-381
-
-
Mellinghoff, I.K.1
Cloughesy, T.F.2
Mischel, P.S.3
-
64
-
-
34047271129
-
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
-
Miracco C, Cosci E, Oliveri G, Luzi P, Pacenti L, Monciatti I, et al, (2007) Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 30: 429-436.
-
(2007)
Int J Oncol
, vol.30
, pp. 429-436
-
-
Miracco, C.1
Cosci, E.2
Oliveri, G.3
Luzi, P.4
Pacenti, L.5
Monciatti, I.6
-
65
-
-
56449094841
-
Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection
-
Nedelsky NB, Todd PK, Taylor JP, (2008) Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection. Biochim Biophys Acta 1782: 691-699.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 691-699
-
-
Nedelsky, N.B.1
Todd, P.K.2
Taylor, J.P.3
-
66
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
DOI 10.1038/35056522
-
Ohsumi Y, (2001) Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2: 211-216. (Pubitemid 33675746)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.3
, pp. 211-216
-
-
Ohsumi, Y.1
-
67
-
-
1342321743
-
Two ubiquitin-like conjugation systems essential for autophagy
-
DOI 10.1016/j.semcdb.2003.12.004
-
Ohsumi Y, Mizushima N, (2004) Two ubiquitin-like conjugation systems essential for autophagy. Semin Cell Dev Biol 15: 231-236. (Pubitemid 38251652)
-
(2004)
Seminars in Cell and Developmental Biology
, vol.15
, Issue.2
, pp. 231-236
-
-
Ohsumi, Y.1
Mizushima, N.2
-
68
-
-
65949106827
-
The plasticity of oncogene addiction: Implications for targeted therapies directed to receptor tyrosine kinases
-
2 following 58.
-
Pillay V, Allaf L, Wilding AL, Donoghue JF, Court NW, Greenall SA, et al, (2009) The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases. Neoplasia 11: 448-458, 2 pp. following 58.
-
(2009)
Neoplasia
, vol.11
, pp. 448-458
-
-
Pillay, V.1
Allaf, L.2
Wilding, A.L.3
Donoghue, J.F.4
Court, N.W.5
Greenall, S.A.6
-
69
-
-
70349649219
-
The prognostic role of Beclin 1 protein expression in high-grade gliomas
-
Pirtoli L, Cevenini G, Tini P, Vannini M, Oliveri G, Marsili S, et al, (2009) The prognostic role of Beclin 1 protein expression in high-grade gliomas. Autophagy 5: 930-936.
-
(2009)
Autophagy
, vol.5
, pp. 930-936
-
-
Pirtoli, L.1
Cevenini, G.2
Tini, P.3
Vannini, M.4
Oliveri, G.5
Marsili, S.6
-
70
-
-
31544474851
-
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
DOI 10.1215/S1522851705000451
-
Prados MD, Lamborn KR, Chang S, Burton E, Butowski N, Malec M, et al, (2006) Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro-oncol 8: 67-78. (Pubitemid 43154453)
-
(2006)
Neuro-Oncology
, vol.8
, Issue.1
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
Burton, E.4
Butowski, N.5
Malec, M.6
Kapadia, A.7
Rabbit, J.8
Page, M.S.9
Fedoroff, A.10
Xie, D.11
Kelley, S.K.12
-
71
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
DOI 10.1172/JCI200320039
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A, et al, (2003) Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112: 1809-1820. (Pubitemid 38063704)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.-L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
72
-
-
0033984094
-
BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites
-
DOI 10.1074/jbc.275.2.1439
-
Ray R, Chen G, Vande Velde C, Cizeau J, Park JH, Reed JC, et al, (2000) BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites. J Biol Chem 275: 1439-1448. (Pubitemid 30051204)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.2
, pp. 1439-1448
-
-
Ray, R.1
Chen, G.2
Velde, C.V.3
Cizeau, J.4
Park, J.H.5
Reed, J.C.6
Daniel Gietz, R.7
Greenberg, A.H.8
-
73
-
-
0036463649
-
Apoptosis-based therapies
-
DOI 10.1038/nrd726
-
Reed JC, (2002) Apoptosis-based therapies. Nat Rev Drug Discov 1: 111-121. (Pubitemid 41646518)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.2
, pp. 111-121
-
-
Reed, J.C.1
-
74
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
DOI 10.1200/JCO.2004.08.110
-
Rich JN, Reardon DA, Peery T, Dowell JM, Quinn JA, Penne KL, et al, (2004) Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 22: 133-142. (Pubitemid 41095125)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.1
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
Dowell, J.M.4
Quinn, J.A.5
Penne, K.L.6
Wikstrand, C.J.7
Van Duyn, L.B.8
Dancey, J.E.9
McLendon, R.E.10
Kao, J.C.11
Stenzel, T.T.12
Rasheed, B.K.A.13
Tourt-Uhlig, S.E.14
Herndon II, J.E.15
Vredenburgh, J.J.16
Sampson, J.H.17
Friedman, A.H.18
Bigner, D.D.19
Friedman, H.S.20
more..
-
75
-
-
79953153832
-
Autophagy and tumorigenesis
-
Roy S, Debnath J, (2010) Autophagy and tumorigenesis. Semin Immunopathol 32: 383-396.
-
(2010)
Semin Immunopathol
, vol.32
, pp. 383-396
-
-
Roy, S.1
Debnath, J.2
-
76
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia A, et al, (2009) Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 119: 1359-1372.
-
(2009)
J Clin Invest
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorente, M.5
Egia, A.6
-
77
-
-
0022384018
-
Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats
-
DOI 10.1016/0014-4827(85)90148-X
-
Schwarze PE, Seglen PO, (1985) Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats. Exp Cell Res 157: 15-28. (Pubitemid 16205864)
-
(1985)
Experimental Cell Research
, vol.157
, Issue.1
, pp. 15-28
-
-
Schwarze, P.E.1
Seglen, P.O.2
-
78
-
-
58749088233
-
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells
-
Shingu T, Fujiwara K, Bogler O, Akiyama Y, Moritake K, Shinojima N, et al, (2009) Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. Int J Cancer 124: 1060-1071.
-
(2009)
Int J Cancer
, vol.124
, pp. 1060-1071
-
-
Shingu, T.1
Fujiwara, K.2
Bogler, O.3
Akiyama, Y.4
Moritake, K.5
Shinojima, N.6
-
79
-
-
70349919804
-
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
-
Simonsen A, Tooze SA, (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 186: 773-782.
-
(2009)
J Cell Biol
, vol.186
, pp. 773-782
-
-
Simonsen, A.1
Tooze, S.A.2
-
80
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
DOI 10.1126/science.1142946
-
Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, et al, (2007) Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 318: 287-290. (Pubitemid 47574858)
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
Nabioullin, R.4
Ponugoti, A.H.5
Wiedemeyer, R.6
Stegh, A.H.7
Bradner, J.E.8
Ligon, K.L.9
Brennan, C.10
Chin, L.11
DePinho, R.A.12
-
81
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al, (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
82
-
-
42149144027
-
Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53
-
DOI 10.1038/sj.bjc.6604258, PII 6604258
-
Szybka M, Zawlik I, Kulczycka D, Golanska E, Jesien E, Kupnicka D, et al, (2008) Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53. Br J Cancer 98: 1431-1433. (Pubitemid 351543567)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.8
, pp. 1431-1433
-
-
Szybka, M.1
Zawlik, I.2
Kulczycka, D.3
Golanska, E.4
Jesien, E.5
Kupnicka, D.6
Stawski, R.7
Piaskowski, S.8
Bieniek, E.9
Zakrzewska, M.10
Kordek, R.11
Liberski, P.P.12
Rieske, P.13
-
83
-
-
0037039442
-
Regulation of starvation- and virus-induced autophagy by the elF2α kinase signaling pathway
-
DOI 10.1073/pnas.012485299
-
Tallõczy Z, Jiang W, Virgin HW, Leib DA, Scheuner D, Kaufman RJ, et al, (2002) Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci USA 99: 190-195. (Pubitemid 34060339)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.1
, pp. 190-195
-
-
Talloczy, Z.1
Jiang, W.2
Virgin IV, H.W.3
Leib, D.A.4
Scheuner, D.5
Kaufman, R.J.6
Eskelinen, E.-L.7
Levine, B.8
-
84
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
DOI 10.1038/ncb1730, PII NCB1730
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, et al, (2008) Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10: 676-687. (Pubitemid 351772933)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
85
-
-
40949107961
-
Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells
-
DOI 10.1093/carcin/bgm264
-
Tiwari M, Bajpai VK, Sahasrabuddhe AA, Kumar A, Sinha RA, Behari S, Godbole MM, (2008) Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells. Carcinogenesis 29: 600-609. (Pubitemid 351404878)
-
(2008)
Carcinogenesis
, vol.29
, Issue.3
, pp. 600-609
-
-
Tiwari, M.1
Bajpai, V.K.2
Sahasrabuddhe, A.A.3
Kumar, A.4
Sinha, R.A.5
Behari, S.6
Godbole, M.M.7
-
86
-
-
78751527443
-
A combined preclinical therapy of cannabinoids and temozolomide against glioma
-
Torres S, Lorente M, Rodriguez-Fornes F, Hernandez-Tiedra S, Salazar M, Garcia-Taboada E, et al, (2011) A combined preclinical therapy of cannabinoids and temozolomide against glioma. Mol Cancer Ther 10: 90-103.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 90-103
-
-
Torres, S.1
Lorente, M.2
Rodriguez-Fornes, F.3
Hernandez-Tiedra, S.4
Salazar, M.5
Garcia-Taboada, E.6
-
87
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
DOI 10.1016/0014-5793(93)80398-E
-
Tsukada M, Ohsumi Y, (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333: 169-174. (Pubitemid 23306962)
-
(1993)
FEBS Letters
, vol.333
, Issue.1-2
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
88
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY, Olson JJ, (2010) Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 60: 166-193.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
Shu, H.K.4
Wen, P.Y.5
Olson, J.J.6
-
89
-
-
79961238261
-
Studies on the administration of quinacrine to tumor-bearing mice
-
Vassey JW, Edmonds J, Irvin JL, Green JA, Irvin EM, (1955) Studies on the administration of quinacrine to tumor-bearing mice. Cancer Res 15: 573-578.
-
(1955)
Cancer Res
, vol.15
, pp. 573-578
-
-
Vassey, J.W.1
Edmonds, J.2
Irvin, J.L.3
Green, J.A.4
Irvin, E.M.5
-
90
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al, (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17: 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
91
-
-
77955432889
-
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma
-
Voss V, Senft C, Lang V, Ronellenfitsch MW, Steinbach JP, Seifert V, Kogel D, (2010) The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res 8: 1002-1016.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1002-1016
-
-
Voss, V.1
Senft, C.2
Lang, V.3
Ronellenfitsch, M.W.4
Steinbach, J.P.5
Seifert, V.6
Kogel, D.7
-
92
-
-
69249153394
-
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
-
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D, Denmark T, (2009) A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 284: 21412-21424.
-
(2009)
J Biol Chem
, vol.284
, pp. 21412-21424
-
-
Wang, J.1
Whiteman, M.W.2
Lian, H.3
Wang, G.4
Singh, A.5
Huang, D.6
Denmark, T.7
-
93
-
-
33748058820
-
Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells
-
DOI 10.1158/0008-5472.CAN-04-4392
-
Wang MY, Lu KV, Zhu S, Dia EQ, Vivanco I, Shackleford GM, et al, (2006) Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. Cancer Res 66: 7864-7869. (Pubitemid 44299148)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 7864-7869
-
-
Wang, M.Y.1
Lu, K.V.2
Zhu, S.3
Dia, E.Q.4
Vivanco, I.5
Shackleford, G.M.6
Cavenee, W.K.7
Mellinghoff, I.K.8
Cloughesy, T.F.9
Sawyers, C.L.10
Mischel, P.S.11
-
94
-
-
42949176742
-
Survival of cancer cells is maintained by EGFR independent of its kinase activity
-
DOI 10.1016/j.ccr.2008.03.015, PII S1535610808001207
-
Weihua Z, Tsan R, Huang WC, Wu Q, Chiu CH, Fidler IJ, Hung MC, (2008) Survival of cancer cells is maintained by EGFR independent of its kinase activity. Cancer Cell 13: 385-393. (Pubitemid 351609444)
-
(2008)
Cancer Cell
, vol.13
, Issue.5
, pp. 385-393
-
-
Weihua, Z.1
Tsan, R.2
Huang, W.-C.3
Wu, Q.4
Chiu, C.-H.5
Fidler, I.J.6
Hung, M.-C.7
-
95
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
Yang Z, Klionsky DJ, (2010) Eaten alive: a history of macroautophagy. Nat Cell Biol 12: 814-822.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
96
-
-
50049112424
-
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells
-
Yokoyama T, Iwado E, Kondo Y, Aoki H, Hayashi Y, Georgescu MM, et al, (2008) Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells. Gene Ther 15: 1233-1239.
-
(2008)
Gene Ther
, vol.15
, pp. 1233-1239
-
-
Yokoyama, T.1
Iwado, E.2
Kondo, Y.3
Aoki, H.4
Hayashi, Y.5
Georgescu, M.M.6
-
97
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF, et al, (2009) Autophagy mediates the mitotic senescence transition. Genes Dev 23: 798-803.
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.6
-
98
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
DOI 10.1073/pnas.2436255100
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N, (2003) Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 100: 15077-15082. (Pubitemid 37518019)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
99
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, et al, (2009) Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol 11: 468-476.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
-
100
-
-
80053302394
-
Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity
-
Zhuang W, Li B, Long L, Chen L, Huang Q, Liang Z, (2011) Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. Int J Cancer 129: 2720-2731.
-
(2011)
Int J Cancer
, vol.129
, pp. 2720-2731
-
-
Zhuang, W.1
Li, B.2
Long, L.3
Chen, L.4
Huang, Q.5
Liang, Z.6
|