-
1
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H., O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira. 2000. A Toll-like receptor recognizes bacterial DNA. Nature 408:740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
2
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai, T., and S. Akira. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11:373-384.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
3
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter, E. A., I. R. Rifkin, A. M. Hohlbaum, B. C. Beaudette, M. J. Shlomchik, and A. Marshak-Rothstein. 2002. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416:603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
4
-
-
27744444832
-
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
-
Lau, C. M., C. Broughton, A. S. Tabor, S. Akira, R. A. Flavell, M. J. Mamula, S. R. Christensen, M. J. Shlomchik, G. A. Viglianti, I. R. Rifkin, and A. Marshak-Rothstein. 2005. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J. Exp. Med. 202:1171-1177.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1171-1177
-
-
Lau, C.M.1
Broughton, C.2
Tabor, A.S.3
Akira, S.4
Flavell, R.A.5
Mamula, M.J.6
Christensen, S.R.7
Shlomchik, M.J.8
Viglianti, G.A.9
Rifkin, I.R.10
Marshak-Rothstein, A.11
-
5
-
-
28544449709
-
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
-
Vollmer, J., S. Tluk, C. Schmitz, S. Hamm, M. Jurk, A. Forsbach, S. Akira, K. M. Kelly, W. H. Reeves, S. Bauer, and A. M. Krieg. 2005. Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J. Exp. Med. 202:1575-1585.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1575-1585
-
-
Vollmer, J.1
Tluk, S.2
Schmitz, C.3
Hamm, S.4
Jurk, M.5
Forsbach, A.6
Akira, S.7
Kelly, K.M.8
Reeves, W.H.9
Bauer, S.10
Krieg, A.M.11
-
6
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
Christensen, S. R., J. Shupe, K. Nickerson, M. Kashgarian, R. A. Flavell, and M. J. Shlomchik. 2006. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25:417-428.
-
(2006)
Immunity
, vol.25
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, R.A.5
Shlomchik, M.J.6
-
7
-
-
77949903821
-
TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
-
Nickerson, K. M., S. R. Christensen, J. Shupe, M. Kashgarian, D. Kim, K. Elkon, and M. J. Shlomchik. 2010. TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus. J. Immunol. 184:1840-1848.
-
(2010)
J. Immunol.
, vol.184
, pp. 1840-1848
-
-
Nickerson, K.M.1
Christensen, S.R.2
Shupe, J.3
Kashgarian, M.4
Kim, D.5
Elkon, K.6
Shlomchik, M.J.7
-
8
-
-
67749135880
-
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
-
Kono, D. H., M. K. Haraldsson, B. R. Lawson, K. M. Pollard, Y. T. Koh, X. Du, C. N. Arnold, R. Baccala, G. J. Silverman, B. A. Beutler, and A. N. Theofilopoulos. 2009. Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus. Proc. Natl. Acad. Sci. USA 106:12061-12066.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12061-12066
-
-
Kono, D.H.1
Haraldsson, M.K.2
Lawson, B.R.3
Pollard, K.M.4
Koh, Y.T.5
Du, X.6
Arnold, C.N.7
Baccala, R.8
Silverman, G.J.9
Beutler, B.A.10
Theofilopoulos, A.N.11
-
9
-
-
84922552164
-
Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands
-
Pawaria, S., K. Moody, P. Busto, K. Nündel, C. H. Choi, T. Ghayur, and A. Marshak-Rothstein. 2015. Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands. J. Immunol. 194:1403-1407.
-
(2015)
J. Immunol.
, vol.194
, pp. 1403-1407
-
-
Pawaria, S.1
Moody, K.2
Busto, P.3
Nündel, K.4
Choi, C.H.5
Ghayur, T.6
Marshak-Rothstein, A.7
-
10
-
-
34249792362
-
Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF) 5 and IRF7 dependent and is required for IL-6 production
-
Yasuda, K., C. Richez, J. W. Maciaszek, N. Agrawal, S. Akira, A. Marshak-Rothstein, and I. R. Rifkin. 2007. Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF) 5 and IRF7 dependent and is required for IL-6 production. J. Immunol. 178:6876-6885.
-
(2007)
J. Immunol.
, vol.178
, pp. 6876-6885
-
-
Yasuda, K.1
Richez, C.2
Maciaszek, J.W.3
Agrawal, N.4
Akira, S.5
Marshak-Rothstein, A.6
Rifkin, I.R.7
-
11
-
-
42449117483
-
Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis
-
Savarese, E., C. Steinberg, R. D. Pawar, W. Reindl, S. Akira, H. J. Anders, and A. Krug. 2008. Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis. Arthritis Rheum. 58:1107-1115.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 1107-1115
-
-
Savarese, E.1
Steinberg, C.2
Pawar, R.D.3
Reindl, W.4
Akira, S.5
Anders, H.J.6
Krug, A.7
-
12
-
-
33748470505
-
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
-
Berland, R., L. Fernandez, E. Kari, J. H. Han, I. Lomakin, S. Akira, H. H. Wortis, J. F. Kearney, A. A. Ucci, and T. Imanishi-Kari. 2006. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity 25:429-440.
-
(2006)
Immunity
, vol.25
, pp. 429-440
-
-
Berland, R.1
Fernandez, L.2
Kari, E.3
Han, J.H.4
Lomakin, I.5
Akira, S.6
Wortis, H.H.7
Kearney, J.F.8
Ucci, A.A.9
Imanishi-Kari, T.10
-
13
-
-
59649107055
-
TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus
-
Lee, P. Y., Y. Kumagai, Y. Li, O. Takeuchi, H. Yoshida, J. Weinstein, E. S. Kellner, D. Nacionales, T. Barker, K. Kelly-Scumpia, et al. 2008. TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus. J. Exp. Med. 205:2995-3006.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2995-3006
-
-
Lee, P.Y.1
Kumagai, Y.2
Li, Y.3
Takeuchi, O.4
Yoshida, H.5
Weinstein, J.6
Kellner, E.S.7
Nacionales, D.8
Barker, T.9
Kelly-Scumpia, K.10
-
14
-
-
84901282428
-
Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation
-
Jackson, S. W., N. E. Scharping, N. S. Kolhatkar, S. Khim, M. A. Schwartz, Q. Z. Li, K. L. Hudkins, C. E. Alpers, D. Liggitt, and D. J. Rawlings. 2014. Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation. J. Immunol. 192:4525-4532.
-
(2014)
J. Immunol.
, vol.192
, pp. 4525-4532
-
-
Jackson, S.W.1
Scharping, N.E.2
Kolhatkar, N.S.3
Khim, S.4
Schwartz, M.A.5
Li, Q.Z.6
Hudkins, K.L.7
Alpers, C.E.8
Liggitt, D.9
Rawlings, D.J.10
-
15
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun, P., J. A. Deane, M. J. Difilippantonio, T. Tarasenko, A. B. Satterthwaite, and S. Bolland. 2006. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312:1669-1672.
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
16
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
Subramanian, S., K. Tus, Q. Z. Li, A. Wang, X. H. Tian, J. Zhou, C. Liang, G. Bartov, L. D. McDaniel, X. J. Zhou, et al. 2006. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl. Acad. Sci. USA 103:9970-9975.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.Z.3
Wang, A.4
Tian, X.H.5
Zhou, J.6
Liang, C.7
Bartov, G.8
McDaniel, L.D.9
Zhou, X.J.10
-
17
-
-
84871122407
-
B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice
-
Hwang, S. H., H. Lee, M. Yamamoto, L. A. Jones, J. Dayalan, R. Hopkins, X. J. Zhou, F. Yarovinsky, J. E. Connolly, M. A. Curotto de Lafaille, et al. 2012. B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice. J. Immunol. 189:5786-5796.
-
(2012)
J. Immunol.
, vol.189
, pp. 5786-5796
-
-
Hwang, S.H.1
Lee, H.2
Yamamoto, M.3
Jones, L.A.4
Dayalan, J.5
Hopkins, R.6
Zhou, X.J.7
Yarovinsky, F.8
Connolly, J.E.9
Curotto De Lafaille, M.A.10
-
18
-
-
36048962438
-
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
-
Deane, J. A., P. Pisitkun, R. S. Barrett, L. Feigenbaum, T. Town, J. M. Ward, R. A. Flavell, and S. Bolland. 2007. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27:801-810.
-
(2007)
Immunity
, vol.27
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
Feigenbaum, L.4
Town, T.5
Ward, J.M.6
Flavell, R.A.7
Bolland, S.8
-
19
-
-
84874853444
-
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice
-
Sun, X., A. Wiedeman, N. Agrawal, T. H. Teal, L. Tanaka, K. L. Hudkins, C. E. Alpers, S. Bolland, M. B. Buechler, J. A. Hamerman, et al. 2013. Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice. J. Immunol. 190:2536-2543.
-
(2013)
J. Immunol.
, vol.190
, pp. 2536-2543
-
-
Sun, X.1
Wiedeman, A.2
Agrawal, N.3
Teal, T.H.4
Tanaka, L.5
Hudkins, K.L.6
Alpers, C.E.7
Bolland, S.8
Buechler, M.B.9
Hamerman, J.A.10
-
20
-
-
84899569537
-
Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus
-
Umiker, B. R., S. Andersson, L. Fernandez, P. Korgaokar, A. Larbi, M. Pilichowska, C. C. Weinkauf, H. H. Wortis, J. F. Kearney, and T. Imanishi-Kari. 2014. Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus. Eur. J. Immunol. 44:1503-1516.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 1503-1516
-
-
Umiker, B.R.1
Andersson, S.2
Fernandez, L.3
Korgaokar, P.4
Larbi, A.5
Pilichowska, M.6
Weinkauf, C.C.7
Wortis, H.H.8
Kearney, J.F.9
Imanishi-Kari, T.10
-
21
-
-
84890840281
-
RNA recognition by human TLR8 can lead to autoimmune inflammation
-
Guiducci, C., M. Gong, A. M. Cepika, Z. Xu, C. Tripodo, L. Bennett, C. Crain, P. Quartier, J. J. Cush, V. Pascual, et al. 2013. RNA recognition by human TLR8 can lead to autoimmune inflammation. J. Exp. Med. 210:2903-2919.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2903-2919
-
-
Guiducci, C.1
Gong, M.2
Cepika, A.M.3
Xu, Z.4
Tripodo, C.5
Bennett, L.6
Crain, C.7
Quartier, P.8
Cush, J.J.9
Pascual, V.10
-
22
-
-
77949879784
-
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: A novel pathway to autoimmune-associated heart block
-
Clancy, R. M., D. Alvarez, E. Komissarova, F. J. Barrat, J. Swartz, and J. P. Buyon. 2010. Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block. J. Immunol. 184:2148-2155.
-
(2010)
J. Immunol.
, vol.184
, pp. 2148-2155
-
-
Clancy, R.M.1
Alvarez, D.2
Komissarova, E.3
Barrat, F.J.4
Swartz, J.5
Buyon, J.P.6
-
23
-
-
34249860408
-
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
-
Graham, R. R., C. Kyogoku, S. Sigurdsson, I. A. Vlasova, L. R. Davies, E. C. Baechler, R. M. Plenge, T. Koeuth, W. A. Ortmann, G. Hom, et al. 2007. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc. Natl. Acad. Sci. USA 104:6758-6763.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6758-6763
-
-
Graham, R.R.1
Kyogoku, C.2
Sigurdsson, S.3
Vlasova, I.A.4
Davies, L.R.5
Baechler, E.C.6
Plenge, R.M.7
Koeuth, T.8
Ortmann, W.A.9
Hom, G.10
-
24
-
-
29244444173
-
Systemic lupus-erythematosus: Deoxyribonuclease 1 in necrotic chromatin disposal
-
Napirei, M., A. Gültekin, T. Kloeckl, T. Möröy, J. Frostegård, and H. G. Mannherz. 2006. Systemic lupus-erythematosus: deoxyribonuclease 1 in necrotic chromatin disposal. Int. J. Biochem. Cell Biol. 38:297-306.
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 297-306
-
-
Napirei, M.1
Gültekin, A.2
Kloeckl, T.3
Möröy, T.4
Frostegård, J.5
Mannherz, H.G.6
-
25
-
-
82255192363
-
Loss-offunction variant in DNASE1L3 causes a familial form of systemic lupus erythematosus
-
Al-Mayouf, S. M., A. Sunker, R. Abdwani, S. A. Abrawi, F. Almurshedi, N. Alhashmi, A. Al Sonbul, W. Sewairi, A. Qari, E. Abdallah, et al. 2011. Loss-offunction variant in DNASE1L3 causes a familial form of systemic lupus erythematosus. Nat. Genet. 43:1186-1188.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1186-1188
-
-
Al-Mayouf, S.M.1
Sunker, A.2
Abdwani, R.3
Abrawi, S.A.4
Almurshedi, F.5
Alhashmi, N.6
Al Sonbul, A.7
Sewairi, W.8
Qari, A.9
Abdallah, E.10
-
26
-
-
33746581694
-
Mutations in the gene encoding the 39-59 DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus
-
Crow, Y. J., B. E. Hayward, R. Parmar, P. Robins, A. Leitch, M. Ali, D. N. Black, H. van Bokhoven, H. G. Brunner, B. C. Hamel, et al. 2006. Mutations in the gene encoding the 39-59 DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. Nat. Genet. 38:917-920.
-
(2006)
Nat. Genet.
, vol.38
, pp. 917-920
-
-
Crow, Y.J.1
Hayward, B.E.2
Parmar, R.3
Robins, P.4
Leitch, A.5
Ali, M.6
Black, D.N.7
Van Bokhoven, H.8
Brunner, H.G.9
Hamel, B.C.10
-
27
-
-
67649861901
-
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
-
Rice, G. I., J. Bond, A. Asipu, R. L. Brunette, I. W. Manfield, I. M. Carr, J. C. Fuller, R. M. Jackson, T. Lamb, T. A. Briggs, et al. 2009. Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response. Nat. Genet. 41:829-832.
-
(2009)
Nat. Genet.
, vol.41
, pp. 829-832
-
-
Rice, G.I.1
Bond, J.2
Asipu, A.3
Brunette, R.L.4
Manfield, I.W.5
Carr, I.M.6
Fuller, J.C.7
Jackson, R.M.8
Lamb, T.9
Briggs, T.A.10
-
28
-
-
84868207785
-
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
-
Rice, G. I., P. R. Kasher, G. M. Forte, N. M. Mannion, S. M. Greenwood, M. Szynkiewicz, J. E. Dickerson, S. S. Bhaskar, M. Zampini, T. A. Briggs, et al. 2012. Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Nat. Genet. 44:1243-1248.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1243-1248
-
-
Rice, G.I.1
Kasher, P.R.2
Forte, G.M.3
Mannion, N.M.4
Greenwood, S.M.5
Szynkiewicz, M.6
Dickerson, J.E.7
Bhaskar, S.S.8
Zampini, M.9
Briggs, T.A.10
-
29
-
-
84880514042
-
Synonymous mutations in RNASEH2A create cryptic splice sites impairing RNase H2 enzyme function in Aicardi-Goutières syndrome
-
Rice, G. I., M. A. Reijns, S. R. Coffin, G. M. Forte, B. H. Anderson, M. Szynkiewicz, H. Gornall, D. Gent, A. Leitch, M. P. Botella, et al. 2013. Synonymous mutations in RNASEH2A create cryptic splice sites impairing RNase H2 enzyme function in Aicardi-Goutières syndrome. Hum. Mutat. 34:1066-1070.
-
(2013)
Hum. Mutat.
, vol.34
, pp. 1066-1070
-
-
Rice, G.I.1
Reijns, M.A.2
Coffin, S.R.3
Forte, G.M.4
Anderson, B.H.5
Szynkiewicz, M.6
Gornall, H.7
Gent, D.8
Leitch, A.9
Botella, M.P.10
-
30
-
-
77950400643
-
Aicardi-Goutieres syndrome and related phenotypes: Linking nucleic acid metabolism with autoimmunity
-
Crow, Y. J., and J. Rehwinkel. 2009. Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity. Hum. Mol. Genet. 18(R2):R130-R136.
-
(2009)
Hum. Mol. Genet.
, vol.18
, Issue.R2
, pp. R130-R136
-
-
Crow, Y.J.1
Rehwinkel, J.2
-
31
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson, D. B., J. S. Ko, T. Heidmann, and R. Medzhitov. 2008. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134:587-598.
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
32
-
-
84869862031
-
Endogenous retroelements and autoimmune disease
-
Stetson, D. B. 2012. Endogenous retroelements and autoimmune disease. Curr. Opin. Immunol. 24:692-697.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 692-697
-
-
Stetson, D.B.1
-
33
-
-
84856301080
-
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
-
Gall, A., P. Treuting, K. B. Elkon, Y. M. Loo, M. Gale, Jr., G. N. Barber, and D. B. Stetson. 2012. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36:120-131.
-
(2012)
Immunity
, vol.36
, pp. 120-131
-
-
Gall, A.1
Treuting, P.2
Elkon, K.B.3
Loo, Y.M.4
Gale, M.5
Barber, G.N.6
Stetson, D.B.7
-
34
-
-
27944453599
-
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
-
Okabe, Y., K. Kawane, S. Akira, T. Taniguchi, and S. Nagata. 2005. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med. 202:1333-1339.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1333-1339
-
-
Okabe, Y.1
Kawane, K.2
Akira, S.3
Taniguchi, T.4
Nagata, S.5
-
35
-
-
12344290452
-
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
-
Yoshida, H., Y. Okabe, K. Kawane, H. Fukuyama, and S. Nagata. 2005. Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat. Immunol. 6:49-56.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 49-56
-
-
Yoshida, H.1
Okabe, Y.2
Kawane, K.3
Fukuyama, H.4
Nagata, S.5
-
36
-
-
33750465224
-
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
-
Kawane, K., M. Ohtani, K. Miwa, T. Kizawa, Y. Kanbara, Y. Yoshioka, H. Yoshikawa, and S. Nagata. 2006. Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443:998-1002.
-
(2006)
Nature
, vol.443
, pp. 998-1002
-
-
Kawane, K.1
Ohtani, M.2
Miwa, K.3
Kizawa, T.4
Kanbara, Y.5
Yoshioka, Y.6
Yoshikawa, H.7
Nagata, S.8
-
37
-
-
78650606709
-
Cytokinedependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
-
Kawane, K., H. Tanaka, Y. Kitahara, S. Shimaoka, and S. Nagata. 2010. Cytokinedependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. Proc. Natl. Acad. Sci. USA 107:19432-19437.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19432-19437
-
-
Kawane, K.1
Tanaka, H.2
Kitahara, Y.3
Shimaoka, S.4
Nagata, S.5
-
38
-
-
84866843867
-
Genetic and expression analysis of SNPs in the human deoxyribonuclease II: SNPs in the promoter region reduce its in vivo activity through decreased promoter activity
-
Kimura-Kataoka, K., T. Yasuda, J. Fujihara, T. Toga, R. Ono, Y. Otsuka, M. Ueki, R. Iida, R. Sano, T. Nakajima, et al. 2012. Genetic and expression analysis of SNPs in the human deoxyribonuclease II: SNPs in the promoter region reduce its in vivo activity through decreased promoter activity. Electrophoresis 33:2852-2858.
-
(2012)
Electrophoresis
, vol.33
, pp. 2852-2858
-
-
Kimura-Kataoka, K.1
Yasuda, T.2
Fujihara, J.3
Toga, T.4
Ono, R.5
Otsuka, Y.6
Ueki, M.7
Iida, R.8
Sano, R.9
Nakajima, T.10
-
39
-
-
0031828264
-
Chronic arthritis in patients with aspartylglucosaminuria
-
Arvio, M. A., J. M. Rapola, and P. M. Pelkonen. 1998. Chronic arthritis in patients with aspartylglucosaminuria. J. Rheumatol. 25:1131-1134.
-
(1998)
J. Rheumatol.
, vol.25
, pp. 1131-1134
-
-
Arvio, M.A.1
Rapola, J.M.2
Pelkonen, P.M.3
-
40
-
-
84855578618
-
Musculoskeletal manifestations of mucopolysaccharidoses
-
Morishita, K., and R. E. Petty. 2011. Musculoskeletal manifestations of mucopolysaccharidoses. Rheumatology (Oxford) 50(Suppl. 5):v19-v25.
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. v19-v25
-
-
Morishita, K.1
Petty, R.E.2
-
41
-
-
84884675857
-
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
-
Li, X. D., J. Wu, D. Gao, H. Wang, L. Sun, and Z. J. Chen. 2013. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science 341:1390-1394.
-
(2013)
Science
, vol.341
, pp. 1390-1394
-
-
Li, X.D.1
Wu, J.2
Gao, D.3
Wang, H.4
Sun, L.5
Chen, Z.J.6
-
42
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner, L., S. E. Keating, M. Baran, K. A. Horan, S. B. Jensen, S. Sharma, C. M. Sirois, T. Jin, E. Latz, T. S. Xiao, et al. 2010. IFI16 is an innate immune sensor for intracellular DNA. Nat. Immunol. 11:997-1004.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
Sirois, C.M.7
Jin, T.8
Latz, E.9
Xiao, T.S.10
-
43
-
-
84880426658
-
The cGAS-STING pathway for DNA sensing
-
Xiao, T. S., and K. A. Fitzgerald. 2013. The cGAS-STING pathway for DNA sensing. Mol. Cell 51:135-139.
-
(2013)
Mol. Cell
, vol.51
, pp. 135-139
-
-
Xiao, T.S.1
Fitzgerald, K.A.2
-
44
-
-
84869794842
-
STING manifests self DNAdependent inflammatory disease
-
Ahn, J., D. Gutman, S. Saijo, and G. N. Barber. 2012. STING manifests self DNAdependent inflammatory disease. Proc. Natl. Acad. Sci. USA 109:19386-19391.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 19386-19391
-
-
Ahn, J.1
Gutman, D.2
Saijo, S.3
Barber, G.N.4
-
45
-
-
84915745085
-
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
-
Jeremiah, N., B. Neven, M. Gentili, I. Callebaut, S. Maschalidi, M. C. Stolzenberg, N. Goudin, M. L. Frémond, P. Nitschke, T. J. Molina, et al. 2014. Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations. J. Clin. Invest. 124:5516-5520.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 5516-5520
-
-
Jeremiah, N.1
Neven, B.2
Gentili, M.3
Callebaut, I.4
Maschalidi, S.5
Stolzenberg, M.C.6
Goudin, N.7
Frémond, M.L.8
Nitschke, P.9
Molina, T.J.10
-
46
-
-
84905825645
-
Activated STING in a vascular and pulmonary syndrome
-
Liu, Y., A. A. Jesus, B. Marrero, D. Yang, S. E. Ramsey, G. A. Montealegre Sanchez, K. Tenbrock, H. Wittkowski, O. Y. Jones, H. S. Kuehn, et al. 2014. Activated STING in a vascular and pulmonary syndrome. N. Engl. J. Med. 371:507-518.
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 507-518
-
-
Liu, Y.1
Jesus, A.A.2
Marrero, B.3
Yang, D.4
Ramsey, S.E.5
Montealegre Sanchez, G.A.6
Tenbrock, K.7
Wittkowski, H.8
Jones, O.Y.9
Kuehn, H.S.10
-
47
-
-
0028288510
-
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
-
Casciola-Rosen, L. A., G. Anhalt, and A. Rosen. 1994. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med. 179:1317-1330.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1317-1330
-
-
Casciola-Rosen, L.A.1
Anhalt, G.2
Rosen, A.3
-
48
-
-
67349124914
-
Immunogenic and tolerogenic cell death
-
Green, D. R., T. Ferguson, L. Zitvogel, and G. Kroemer. 2009. Immunogenic and tolerogenic cell death. Nat. Rev. Immunol. 9:353-363.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 353-363
-
-
Green, D.R.1
Ferguson, T.2
Zitvogel, L.3
Kroemer, G.4
-
49
-
-
78049493046
-
Apoptosis and autoimmune diseases
-
Nagata, S. 2010. Apoptosis and autoimmune diseases. Ann. N. Y. Acad. Sci. 1209:10-16.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1209
, pp. 10-16
-
-
Nagata, S.1
-
50
-
-
70449464779
-
Activating systemic autoimmunity: B's, T's, and tolls
-
Shlomchik, M. J. 2009. Activating systemic autoimmunity: B's, T's, and tolls. Curr. Opin. Immunol. 21:626-633.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 626-633
-
-
Shlomchik, M.J.1
-
51
-
-
84907996785
-
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy
-
Lan, Y. Y., D. Londoño, R. Bouley, M. S. Rooney, and N. Hacohen. 2014. Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy. Cell Reports 9:180-192.
-
(2014)
Cell Reports
, vol.9
, pp. 180-192
-
-
Lan, Y.Y.1
Londoño, D.2
Bouley, R.3
Rooney, M.S.4
Hacohen, N.5
-
52
-
-
84919898250
-
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
-
Rongvaux, A., R. Jackson, C. C. Harman, T. Li, A. P. West, M. R. de Zoete, Y. Wu, B. Yordy, S. A. Lakhani, C. Y. Kuan, et al. 2014. Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell 159:1563-1577.
-
(2014)
Cell
, vol.159
, pp. 1563-1577
-
-
Rongvaux, A.1
Jackson, R.2
Harman, C.C.3
Li, T.4
West, A.P.5
De Zoete, M.R.6
Wu, Y.7
Yordy, B.8
Lakhani, S.A.9
Kuan, C.Y.10
-
53
-
-
84928537166
-
Mitochondrial DNA stress primes the antiviral innate immune response
-
West, A. P., W. Khoury-Hanold, M. Staron, M. C. Tal, C. M. Pineda, S. M. Lang, M. Bestwick, B. A. Duguay, N. Raimundo, D. A. MacDuff, et al. 2015. Mitochondrial DNA stress primes the antiviral innate immune response. Nature 520:553-557.
-
(2015)
Nature
, vol.520
, pp. 553-557
-
-
West, A.P.1
Khoury-Hanold, W.2
Staron, M.3
Tal, M.C.4
Pineda, C.M.5
Lang, S.M.6
Bestwick, M.7
Duguay, B.A.8
Raimundo, N.9
MacDuff, D.A.10
-
54
-
-
52949095077
-
Retrotransposons revisited: The restraint and rehabilitation of parasites
-
Goodier, J. L., and H. H. Kazazian, Jr. 2008. Retrotransposons revisited: the restraint and rehabilitation of parasites. Cell 135:23-35.
-
(2008)
Cell
, vol.135
, pp. 23-35
-
-
Goodier, J.L.1
Kazazian, H.H.2
-
55
-
-
84870294763
-
Resurrection of endogenous retroviruses in antibody-deficient mice
-
Young, G. R., U. Eksmond, R. Salcedo, L. Alexopoulou, J. P. Stoye, and G. Kassiotis. 2012. Resurrection of endogenous retroviruses in antibody-deficient mice. Nature 491:774-778.
-
(2012)
Nature
, vol.491
, pp. 774-778
-
-
Young, G.R.1
Eksmond, U.2
Salcedo, R.3
Alexopoulou, L.4
Stoye, J.P.5
Kassiotis, G.6
-
56
-
-
84919443956
-
MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses
-
Zeng, M., Z. Hu, X. Shi, X. Li, X. Zhan, X. D. Li, J. Wang, J. H. Choi, K. W. Wang, T. Purrington, et al. 2014. MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses. Science 346:1486-1492.
-
(2014)
Science
, vol.346
, pp. 1486-1492
-
-
Zeng, M.1
Hu, Z.2
Shi, X.3
Li, X.4
Zhan, X.5
Li, X.D.6
Wang, J.7
Choi, J.H.8
Wang, K.W.9
Purrington, T.10
-
57
-
-
84871960929
-
The cell biology of disease: Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
-
Platt, F. M., B. Boland, and A. C. van der Spoel. 2012. The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction. J. Cell Biol. 199:723-734.
-
(2012)
J. Cell Biol.
, vol.199
, pp. 723-734
-
-
Platt, F.M.1
Boland, B.2
Van Der Spoel, A.C.3
-
58
-
-
84921478452
-
Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice
-
Baum, R., S. Sharma, S. Carpenter, Q. Z. Li, P. Busto, K. A. Fitzgerald, A. Marshak-Rothstein, and E. M. Gravallese. 2015. Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice. J. Immunol. 194:873-877.
-
(2015)
J. Immunol.
, vol.194
, pp. 873-877
-
-
Baum, R.1
Sharma, S.2
Carpenter, S.3
Li, Q.Z.4
Busto, P.5
Fitzgerald, K.A.6
Marshak-Rothstein, A.7
Gravallese, E.M.8
-
59
-
-
80052275825
-
Mitochondria in innate immunity
-
Arnoult, D., F. Soares, I. Tattoli, and S. E. Girardin. 2011. Mitochondria in innate immunity. EMBO Rep. 12:901-910.
-
(2011)
EMBO Rep.
, vol.12
, pp. 901-910
-
-
Arnoult, D.1
Soares, F.2
Tattoli, I.3
Girardin, S.E.4
-
60
-
-
84919884654
-
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production
-
White, M. J., K. McArthur, D. Metcalf, R. M. Lane, J. C. Cambier, M. J. Herold, M. F. van Delft, S. Bedoui, G. Lessene, M. E. Ritchie, et al. 2014. Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell 159:1549-1562.
-
(2014)
Cell
, vol.159
, pp. 1549-1562
-
-
White, M.J.1
McArthur, K.2
Metcalf, D.3
Lane, R.M.4
Cambier, J.C.5
Herold, M.J.6
Van Delft, M.F.7
Bedoui, S.8
Lessene, G.9
Ritchie, M.E.10
-
61
-
-
33745864016
-
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus
-
Lartigue, A., P. Courville, I. Auquit, A. François, C. Arnoult, F. Tron, D. Gilbert, and P. Musette. 2006. Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus. J. Immunol. 177:1349-1354.
-
(2006)
J. Immunol.
, vol.177
, pp. 1349-1354
-
-
Lartigue, A.1
Courville, P.2
Auquit, I.3
François, A.4
Arnoult, C.5
Tron, F.6
Gilbert, D.7
Musette, P.8
-
62
-
-
77952242576
-
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice
-
Santiago-Raber, M. L., I. Dunand-Sauthier, T. Wu, Q. Z. Li, S. Uematsu, S. Akira, W. Reith, C. Mohan, B. L. Kotzin, and S. Izui. 2010. Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. J. Autoimmun. 34:339-348.
-
(2010)
J. Autoimmun.
, vol.34
, pp. 339-348
-
-
Santiago-Raber, M.L.1
Dunand-Sauthier, I.2
Wu, T.3
Li, Q.Z.4
Uematsu, S.5
Akira, S.6
Reith, W.7
Mohan, C.8
Kotzin, B.L.9
Izui, S.10
-
63
-
-
33748465308
-
Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE
-
Yu, P., U. Wellmann, S. Kunder, L. Quintanilla-Martinez, L. Jennen, N. Dear, K. Amann, S. Bauer, T. H. Winkler, and H. Wagner. 2006. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. Int. Immunol. 18:1211-1219.
-
(2006)
Int. Immunol.
, vol.18
, pp. 1211-1219
-
-
Yu, P.1
Wellmann, U.2
Kunder, S.3
Quintanilla-Martinez, L.4
Jennen, L.5
Dear, N.6
Amann, K.7
Bauer, S.8
Winkler, T.H.9
Wagner, H.10
-
64
-
-
84881559292
-
UNC93B1 mediates differential trafficking of endosomal TLRs
-
Lee, B. L., J. E. Moon, J. H. Shu, L. Yuan, Z. R. Newman, R. Schekman, and G. M. Barton. 2013. UNC93B1 mediates differential trafficking of endosomal TLRs. eLife 2:e00291.
-
(2013)
ELife
, vol.2
, pp. e00291
-
-
Lee, B.L.1
Moon, J.E.2
Shu, J.H.3
Yuan, L.4
Newman, Z.R.5
Schekman, R.6
Barton, G.M.7
-
65
-
-
84872171591
-
Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice
-
Avalos, A. M., O. Kirak, J. M. Oelkers, M. C. Pils, Y. M. Kim, M. Ottinger, R. Jaenisch, H. L. Ploegh, and M. M. Brinkmann. 2013. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice. J. Immunol. 190:695-702.
-
(2013)
J. Immunol.
, vol.190
, pp. 695-702
-
-
Avalos, A.M.1
Kirak, O.2
Oelkers, J.M.3
Pils, M.C.4
Kim, Y.M.5
Ottinger, M.6
Jaenisch, R.7
Ploegh, H.L.8
Brinkmann, M.M.9
-
66
-
-
80053071417
-
TLR9 in peritoneal B-1β cells is essential for production of protective self-reactive IgM to control Th17 cells and severe autoimmunity
-
Stoehr, A. D., C. T. Schoen, M. M. Mertes, S. Eiglmeier, V. Holecska, A. K. Lorenz, T. Schommartz, A. L. Schoen, C. Hess, A. Winkler, et al. 2011. TLR9 in peritoneal B-1β cells is essential for production of protective self-reactive IgM to control Th17 cells and severe autoimmunity. J. Immunol. 187:2953-2965.
-
(2011)
J. Immunol.
, vol.187
, pp. 2953-2965
-
-
Stoehr, A.D.1
Schoen, C.T.2
Mertes, M.M.3
Eiglmeier, S.4
Holecska, V.5
Lorenz, A.K.6
Schommartz, T.7
Schoen, A.L.8
Hess, C.9
Winkler, A.10
-
67
-
-
84924565569
-
Cellintrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses
-
Nündel, K., N. M. Green, A. L. Shaffer, K. L. Moody, P. Busto, D. Eilat, K. Miyake, M. A. Oropallo, M. P. Cancro, and A. Marshak-Rothstein. 2015. Cellintrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses. J. Immunol. 194:2504-2512.
-
(2015)
J. Immunol.
, vol.194
, pp. 2504-2512
-
-
Nündel, K.1
Green, N.M.2
Shaffer, A.L.3
Moody, K.L.4
Busto, P.5
Eilat, D.6
Miyake, K.7
Oropallo, M.A.8
Cancro, M.P.9
Marshak-Rothstein, A.10
-
68
-
-
55349142293
-
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
-
Isnardi, I., Y. S. Ng, I. Srdanovic, R. Motaghedi, S. Rudchenko, H. von Bernuth, S. Y. Zhang, A. Puel, E. Jouanguy, C. Picard, et al. 2008. IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 29:746-757.
-
(2008)
Immunity
, vol.29
, pp. 746-757
-
-
Isnardi, I.1
Ng, Y.S.2
Srdanovic, I.3
Motaghedi, R.4
Rudchenko, S.5
Von Bernuth, H.6
Zhang, S.Y.7
Puel, A.8
Jouanguy, E.9
Picard, C.10
-
69
-
-
84873557459
-
TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation
-
Nickerson, K. M., S. R. Christensen, J. L. Cullen, W. Meng, E. T. Luning Prak, and M. J. Shlomchik. 2013. TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation. J. Immunol. 190:1447-1456.
-
(2013)
J. Immunol.
, vol.190
, pp. 1447-1456
-
-
Nickerson, K.M.1
Christensen, S.R.2
Cullen, J.L.3
Meng, W.4
Luning Prak, E.T.5
Shlomchik, M.J.6
-
70
-
-
84923169931
-
Suppression of systemic autoimmunity by the innate immune adaptor STING
-
Sharma, S., A. M. Campbell, J. Chan, S. A. Schattgen, G. M. Orlowski, R. Nayar, A. H. Huyler, K. Nündel, C. Mohan, L. J. Berg, et al. 2015. Suppression of systemic autoimmunity by the innate immune adaptor STING. Proc. Natl. Acad. Sci. USA 112:E710-E717.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E710-E717
-
-
Sharma, S.1
Campbell, A.M.2
Chan, J.3
Schattgen, S.A.4
Orlowski, G.M.5
Nayar, R.6
Huyler, A.H.7
Nündel, K.8
Mohan, C.9
Berg, L.J.10
-
71
-
-
84941201188
-
STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells
-
Dong, G., M. You, L. Ding, H. Fan, F. Liu, D. Ren, and Y. Hou. 2015. STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells. Mol. Cells 38:441-451.
-
(2015)
Mol. Cells
, vol.38
, pp. 441-451
-
-
Dong, G.1
You, M.2
Ding, L.3
Fan, H.4
Liu, F.5
Ren, D.6
Hou, Y.7
-
72
-
-
80054694130
-
Activation of STAT6 by STING is critical for antiviral innate immunity
-
Chen, H., H. Sun, F. You, W. Sun, X. Zhou, L. Chen, J. Yang, Y. Wang, H. Tang, Y. Guan, et al. 2011. Activation of STAT6 by STING is critical for antiviral innate immunity. Cell 147:436-446.
-
(2011)
Cell
, vol.147
, pp. 436-446
-
-
Chen, H.1
Sun, H.2
You, F.3
Sun, W.4
Zhou, X.5
Chen, L.6
Yang, J.7
Wang, Y.8
Tang, H.9
Guan, Y.10
-
73
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence, T., and G. Natoli. 2011. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 11:750-761.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
74
-
-
84863231381
-
Tolerance to apoptotic cells is regulated by indoleamine 2, 3-dioxygenase
-
Ravishankar, B., H. Liu, R. Shinde, P. Chandler, B. Baban, M. Tanaka, D. H. Munn, A. L. Mellor, M. C. Karlsson, and T. L. McGaha. 2012. Tolerance to apoptotic cells is regulated by indoleamine 2, 3-dioxygenase. Proc. Natl. Acad. Sci. USA 109:3909-3914.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3909-3914
-
-
Ravishankar, B.1
Liu, H.2
Shinde, R.3
Chandler, P.4
Baban, B.5
Tanaka, M.6
Munn, D.H.7
Mellor, A.L.8
Karlsson, M.C.9
McGaha, T.L.10
-
75
-
-
84896346304
-
Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity
-
Jin, J., H. Hu, H. S. Li, J. Yu, Y. Xiao, G. C. Brittain, Q. Zou, X. Cheng, F. A. Mallette, S. S. Watowich, and S. C. Sun. 2014. Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity. Immunity 40:342-354.
-
(2014)
Immunity
, vol.40
, pp. 342-354
-
-
Jin, J.1
Hu, H.2
Li, H.S.3
Yu, J.4
Xiao, Y.5
Brittain, G.C.6
Zou, Q.7
Cheng, X.8
Mallette, F.A.9
Watowich, S.S.10
Sun, S.C.11
-
76
-
-
84862622032
-
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses
-
Negishi, H., H. Yanai, A. Nakajima, R. Koshiba, K. Atarashi, A. Matsuda, K. Matsuki, S. Miki, T. Doi, A. Aderem, et al. 2012. Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat. Immunol. 13:659-666.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 659-666
-
-
Negishi, H.1
Yanai, H.2
Nakajima, A.3
Koshiba, R.4
Atarashi, K.5
Matsuda, A.6
Matsuki, K.7
Miki, S.8
Doi, T.9
Aderem, A.10
-
77
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
-
Parroche, P., F. N. Lauw, N. Goutagny, E. Latz, B. G. Monks, A. Visintin, K. A. Halmen, M. Lamphier, M. Olivier, D. C. Bartholomeu, et al. 2007. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. USA 104:1919-1924.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1919-1924
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
Latz, E.4
Monks, B.G.5
Visintin, A.6
Halmen, K.A.7
Lamphier, M.8
Olivier, M.9
Bartholomeu, D.C.10
-
78
-
-
77952757782
-
Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses
-
Wu, X., N. M. Gowda, S. Kumar, and D. C. Gowda. 2010. Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses. J. Immunol. 184:4338-4348.
-
(2010)
J. Immunol.
, vol.184
, pp. 4338-4348
-
-
Wu, X.1
Gowda, N.M.2
Kumar, S.3
Gowda, D.C.4
-
79
-
-
80051880722
-
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome
-
Sharma, S., R. B. DeOliveira, P. Kalantari, P. Parroche, N. Goutagny, Z. Jiang, J. Chan, D. C. Bartholomeu, F. Lauw, J. P. Hall, et al. 2011. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity 35:194-207.
-
(2011)
Immunity
, vol.35
, pp. 194-207
-
-
Sharma, S.1
DeOliveira, R.B.2
Kalantari, P.3
Parroche, P.4
Goutagny, N.5
Jiang, Z.6
Chan, J.7
Bartholomeu, D.C.8
Lauw, F.9
Hall, J.P.10
-
80
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta, K., P. Georgel, E. Janssen, X. Du, K. Hoebe, K. Crozat, S. Mudd, L. Shamel, S. Sovath, J. Goode, et al. 2004. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc. Natl. Acad. Sci. USA 101:3516-3521.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
Du, X.4
Hoebe, K.5
Crozat, K.6
Mudd, S.7
Shamel, L.8
Sovath, S.9
Goode, J.10
-
81
-
-
44449165607
-
Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection
-
Zucchini, N., G. Bessou, S. Traub, S. H. Robbins, S. Uematsu, S. Akira, L. Alexopoulou, and M. Dalod. 2008. Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection. J. Immunol. 180:5799-5803.
-
(2008)
J. Immunol.
, vol.180
, pp. 5799-5803
-
-
Zucchini, N.1
Bessou, G.2
Traub, S.3
Robbins, S.H.4
Uematsu, S.5
Akira, S.6
Alexopoulou, L.7
Dalod, M.8
-
82
-
-
84895904323
-
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
-
Schoggins, J. W., D. A. MacDuff, N. Imanaka, M. D. Gainey, B. Shrestha, J. L. Eitson, K. B. Mar, R. B. Richardson, A. V. Ratushny, V. Litvak, et al. 2014. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature 505:691-695.
-
(2014)
Nature
, vol.505
, pp. 691-695
-
-
Schoggins, J.W.1
MacDuff, D.A.2
Imanaka, N.3
Gainey, M.D.4
Shrestha, B.5
Eitson, J.L.6
Mar, K.B.7
Richardson, R.B.8
Ratushny, A.V.9
Litvak, V.10
|