TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1447-1456

  Nickerson, Kevin M ^a   Christensen, Sean R ^a   Cullen, Jaime L ^a   Meng, Wenzhao ^b   Eline T Luning Prak, ^b   Shlomchik, Mark J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; DNA ANTIBODY; IMMUNOGLOBULIN LIGHT CHAIN; NUCLEOSOME ANTIBODY; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTI DNA B CELL; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY REACTION; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL COMPONENT; CELL FOLLICLE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CLONAL ANERGY; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; INTRACELLULAR SIGNALING; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; RECEPTOR EDITING; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSGENE;

ANIMALS; B-LYMPHOCYTE SUBSETS; CLONAL ANERGY; DNA; GROWTH INHIBITORS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED MRL LPR; MICE, KNOCKOUT; MICE, TRANSGENIC; RADIATION CHIMERA; TOLL-LIKE RECEPTOR 9;

EID: 84873557459     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202115     Document Type: Article

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