Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy

Cell Reports

Volumn 9, Issue 1, 2014, Pages 180-192

  Lan, YukYuen ^a,b,c   Londoño, Diana ^a,e   Bouley, Richard ^a   Rooney, MichaelS ^b,d   Hacohen, Nir ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^e UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL NUCLEUS DNA; DEOXYRIBONUCLEASE II; DEOXYRIBONUCLEASE IIA; PROTEIN STING; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELLULAR DISTRIBUTION; CELLULAR PARAMETERS; CLEARANCE; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; DNA DEGRADATION; ENZYME DEFICIENCY; IMAGING AND DISPLAY; INFLAMMATION; LIVE CELL IMAGING; LYSOSOMAL CLEARANCE; MOUSE; NONHUMAN; NUCLEAR EXPORT; PHAGOCYTOSIS; SIGNAL TRANSDUCTION; ANIMAL; CELL NUCLEUS; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; GENETICS; HUMAN; LYSOSOME; METABOLISM; PHAGOCYTE;

ANIMALS; AUTOPHAGY; CELL NUCLEUS; DNA; DNA DAMAGE; ENDODEOXYRIBONUCLEASES; HUMANS; LYSOSOMES; MICE; PHAGOCYTES;

EID: 84907996785     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.08.074     Document Type: Article

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