-
1
-
-
0029994333
-
Systemic lupus erythematosus
-
Kotzin B. Systemic lupus erythematosus. Cell 85 (1996) 303-306
-
(1996)
Cell
, vol.85
, pp. 303-306
-
-
Kotzin, B.1
-
2
-
-
39049142995
-
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
-
This report of a double blind clinical study of rituximab treatment for relapsing-remitting MS patients showed remarkable efficacy, implicating B cells in a human autoimmune disease previously thought to be T cell mediated.
-
Hauser S.L., Waubant E., Arnold D.L., Vollmer T., Antel J., Fox R.J., Bar-Or A., Panzara M., Sarkar N., Agarwal S., et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 358 (2008) 676-688. This report of a double blind clinical study of rituximab treatment for relapsing-remitting MS patients showed remarkable efficacy, implicating B cells in a human autoimmune disease previously thought to be T cell mediated.
-
(2008)
N Engl J Med
, vol.358
, pp. 676-688
-
-
Hauser, S.L.1
Waubant, E.2
Arnold, D.L.3
Vollmer, T.4
Antel, J.5
Fox, R.J.6
Bar-Or, A.7
Panzara, M.8
Sarkar, N.9
Agarwal, S.10
-
3
-
-
36849027817
-
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice
-
B cell depletion in NOD mice was shown to prevent diabetes and strikingly, to induce remission in newly diabetic animals, again showing the role of B cells in ongoing disease thought to be T cell mediated.
-
Hu C.Y., Rodriguez-Pinto D., Du W., Ahuja A., Henegariu O., Wong F.S., Shlomchik M.J., and Wen L. Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice. J Clin Invest 117 (2007) 3857-3867. B cell depletion in NOD mice was shown to prevent diabetes and strikingly, to induce remission in newly diabetic animals, again showing the role of B cells in ongoing disease thought to be T cell mediated.
-
(2007)
J Clin Invest
, vol.117
, pp. 3857-3867
-
-
Hu, C.Y.1
Rodriguez-Pinto, D.2
Du, W.3
Ahuja, A.4
Henegariu, O.5
Wong, F.S.6
Shlomchik, M.J.7
Wen, L.8
-
4
-
-
0032769336
-
The central and multiple roles of B cells in lupus pathogenesis
-
Chan O.T.M., Madaio M.P., and Shlomchik M.J. The central and multiple roles of B cells in lupus pathogenesis. Immunol Rev 169 (1999) 107-121
-
(1999)
Immunol Rev
, vol.169
, pp. 107-121
-
-
Chan, O.T.M.1
Madaio, M.P.2
Shlomchik, M.J.3
-
5
-
-
0035525528
-
From T to B and back again: positive feedback in systemic autoimmune disease
-
Shlomchik M.J., Craft J.E., and Mamula M.J. From T to B and back again: positive feedback in systemic autoimmune disease. Nat Rev Immunol 1 (2001) 147-153
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 147-153
-
-
Shlomchik, M.J.1
Craft, J.E.2
Mamula, M.J.3
-
6
-
-
0033214474
-
B cells are required for lupus nephritis in the polygenic. Fas-intact MRL model of systemic autoimmunity
-
Chan O.T., Madaio M.P., and Shlomchik M.J. B cells are required for lupus nephritis in the polygenic. Fas-intact MRL model of systemic autoimmunity. J Immunol 163 (1999) 3592-3596
-
(1999)
J Immunol
, vol.163
, pp. 3592-3596
-
-
Chan, O.T.1
Madaio, M.P.2
Shlomchik, M.J.3
-
7
-
-
0031882091
-
A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
-
Chan O., and Shlomchik M.J. A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J Immunol 160 (1998) 51-59
-
(1998)
J Immunol
, vol.160
, pp. 51-59
-
-
Chan, O.1
Shlomchik, M.J.2
-
8
-
-
0027983579
-
The role of B cells in lpr/lpr-induced autoimmunity
-
Shlomchik M.J., Madaio M.P., Ni D., Trounstein M., and Huszar D. The role of B cells in lpr/lpr-induced autoimmunity. J Exp Med 180 (1994) 1295-1306
-
(1994)
J Exp Med
, vol.180
, pp. 1295-1306
-
-
Shlomchik, M.J.1
Madaio, M.P.2
Ni, D.3
Trounstein, M.4
Huszar, D.5
-
9
-
-
0033577903
-
A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
-
Chan O.T., Hannum L.G., Haberman A.M., Madaio M.P., and Shlomchik M.J. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189 (1999) 1639-1648
-
(1999)
J Exp Med
, vol.189
, pp. 1639-1648
-
-
Chan, O.T.1
Hannum, L.G.2
Haberman, A.M.3
Madaio, M.P.4
Shlomchik, M.J.5
-
10
-
-
45449099469
-
Cytokine-producing B lymphocytes-key regulators of immunity
-
Lund F.E. Cytokine-producing B lymphocytes-key regulators of immunity. Curr Opin Immunol 20 (2008) 332-338
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 332-338
-
-
Lund, F.E.1
-
11
-
-
27744501244
-
B cells as a therapeutic target in autoimmune diseases other than rheumatoid arthritis
-
Looney R.J. B cells as a therapeutic target in autoimmune diseases other than rheumatoid arthritis. Rheumatology (Oxford) 44 Suppl 2 (2005) ii13-ii17
-
(2005)
Rheumatology (Oxford)
, vol.44
, Issue.SUPPL. 2
-
-
Looney, R.J.1
-
12
-
-
0041571732
-
Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis
-
Cambridge G., Leandro M.J., Edwards J.C., Ehrenstein M.R., Salden M., Bodman-Smith M., and Webster A.D. Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis. Arthritis Rheum 48 (2003) 2146-2154
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2146-2154
-
-
Cambridge, G.1
Leandro, M.J.2
Edwards, J.C.3
Ehrenstein, M.R.4
Salden, M.5
Bodman-Smith, M.6
Webster, A.D.7
-
13
-
-
36849090653
-
Depletion of B cells in murine lupus: efficacy and resistance
-
B cell depletion in MRL/lpr mice was severely impaired, implying a barrier to depletion associated with lupus. However, long-term treatment did deplete B cells, with resultant clinical improvement and reduction in T cell activation.
-
Ahuja A., Shupe J., Dunn R., Kashgarian M., Kehry M.R., and Shlomchik M.J. Depletion of B cells in murine lupus: efficacy and resistance. J Immunol 179 (2007) 3351-3361. B cell depletion in MRL/lpr mice was severely impaired, implying a barrier to depletion associated with lupus. However, long-term treatment did deplete B cells, with resultant clinical improvement and reduction in T cell activation.
-
(2007)
J Immunol
, vol.179
, pp. 3351-3361
-
-
Ahuja, A.1
Shupe, J.2
Dunn, R.3
Kashgarian, M.4
Kehry, M.R.5
Shlomchik, M.J.6
-
14
-
-
13444252282
-
Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial
-
Sfikakis P.P., Boletis J.N., Lionaki S., Vigklis V., Fragiadaki K.G., Iniotaki A., and Moutsopoulos H.M. Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial. Arthritis Rheum 52 (2005) 501-513
-
(2005)
Arthritis Rheum
, vol.52
, pp. 501-513
-
-
Sfikakis, P.P.1
Boletis, J.N.2
Lionaki, S.3
Vigklis, V.4
Fragiadaki, K.G.5
Iniotaki, A.6
Moutsopoulos, H.M.7
-
15
-
-
38049186677
-
Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice
-
With newly developed anti-mCD20 mAbs, the authors depleted B cells and directly showed effects on induced and spontaneous T cell activation in autoimmune settings, such as diabetes.
-
Bouaziz J.-D., Yanaba K., Venturi G.M., Wang Y., Tisch R.M., Poe J.C., and Tedder T.F. Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice. Proc Natl Acad Sci U S A 104 (2007) 20878-20883. With newly developed anti-mCD20 mAbs, the authors depleted B cells and directly showed effects on induced and spontaneous T cell activation in autoimmune settings, such as diabetes.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20878-20883
-
-
Bouaziz, J.-D.1
Yanaba, K.2
Venturi, G.M.3
Wang, Y.4
Tisch, R.M.5
Poe, J.C.6
Tedder, T.F.7
-
16
-
-
2442494120
-
Autoimmunity through cytokine-induced dendritic cell activation
-
Banchereau J., Pascual V., and Palucka A.K. Autoimmunity through cytokine-induced dendritic cell activation. Immunity 20 (2004) 539-550
-
(2004)
Immunity
, vol.20
, pp. 539-550
-
-
Banchereau, J.1
Pascual, V.2
Palucka, A.K.3
-
17
-
-
0025574407
-
Dendritic cells as antigen presenting cells in vivo
-
Inaba K., Metlay J.P., Crowley M.T., Witmer-Pack M., and Steinman R.M. Dendritic cells as antigen presenting cells in vivo. Int Rev Immunol 6 (1990) 197-206
-
(1990)
Int Rev Immunol
, vol.6
, pp. 197-206
-
-
Inaba, K.1
Metlay, J.P.2
Crowley, M.T.3
Witmer-Pack, M.4
Steinman, R.M.5
-
18
-
-
18344369175
-
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells
-
Seo S.J., Fields M.L., Buckler J.L., Reed A.J., Mandik-Nayak L., Nish S.A., Noelle R.J., Turka L.A., Finkelman F.D., Caton A.J., et al. The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity 16 (2002) 535-546
-
(2002)
Immunity
, vol.16
, pp. 535-546
-
-
Seo, S.J.1
Fields, M.L.2
Buckler, J.L.3
Reed, A.J.4
Mandik-Nayak, L.5
Nish, S.A.6
Noelle, R.J.7
Turka, L.A.8
Finkelman, F.D.9
Caton, A.J.10
-
19
-
-
0036533552
-
Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance
-
Yan J., and Mamula M.J. Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance. J Immunol 168 (2002) 3188-3194
-
(2002)
J Immunol
, vol.168
, pp. 3188-3194
-
-
Yan, J.1
Mamula, M.J.2
-
20
-
-
37549049335
-
Anti-chromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites
-
Herlands R.A., William J., Hershberg U., and Shlomchik M.J. Anti-chromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites. Eur J Immunol 37 (2007) 3339-3351
-
(2007)
Eur J Immunol
, vol.37
, pp. 3339-3351
-
-
Herlands, R.A.1
William, J.2
Hershberg, U.3
Shlomchik, M.J.4
-
21
-
-
0027505015
-
A rheumatoid factor transgenic mouse model of autoantibody regulation
-
Shlomchik M.J., Zharhary D., Saunders T., Camper S., and Weigert M. A rheumatoid factor transgenic mouse model of autoantibody regulation. Int Immunol 5 (1993) 1329-1341
-
(1993)
Int Immunol
, vol.5
, pp. 1329-1341
-
-
Shlomchik, M.J.1
Zharhary, D.2
Saunders, T.3
Camper, S.4
Weigert, M.5
-
22
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter E.A., Rifkin I.R., Hohlbaum A.M., Beaudette B.C., Shlomchik M.J., and Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416 (2002) 603-607
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
23
-
-
0034254310
-
Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells [In Process Citation]
-
Rifkin I.R., Leadbetter E.A., Beaudette B.C., Kiani C., Monestier M., Shlomchik M.J., and Marshak-Rothstein A. Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells [In Process Citation]. J Immunol 165 (2000) 1626-1633
-
(2000)
J Immunol
, vol.165
, pp. 1626-1633
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Beaudette, B.C.3
Kiani, C.4
Monestier, M.5
Shlomchik, M.J.6
Marshak-Rothstein, A.7
-
24
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin I.R., Leadbetter E.A., Busconi L., Viglianti G., and Marshak-Rothstein A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol Rev 204 (2005) 27-42
-
(2005)
Immunol Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
25
-
-
27744444832
-
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
-
Lau C.M., Broughton C., Tabor A.S., Akira S., Flavell R.A., Mamula M.J., Christensen S.R., Shlomchik M.J., Viglianti G.A., Rifkin I.R., et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med 202 (2005) 1171-1177
-
(2005)
J Exp Med
, vol.202
, pp. 1171-1177
-
-
Lau, C.M.1
Broughton, C.2
Tabor, A.S.3
Akira, S.4
Flavell, R.A.5
Mamula, M.J.6
Christensen, S.R.7
Shlomchik, M.J.8
Viglianti, G.A.9
Rifkin, I.R.10
-
26
-
-
0347480224
-
Activation of autoreactive B cells by CpG dsDNA
-
Viglianti G.A., Lau C.M., Hanley T.M., Miko B.A., Shlomchik M.J., and Marshak-Rothstein A. Activation of autoreactive B cells by CpG dsDNA. Immunity 19 (2003) 837-847
-
(2003)
Immunity
, vol.19
, pp. 837-847
-
-
Viglianti, G.A.1
Lau, C.M.2
Hanley, T.M.3
Miko, B.A.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
27
-
-
22944490869
-
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
-
Christensen S.R., Kashgarian M., Alexopoulou L., Flavell R.A., Akira S., and Shlomchik M.J. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 202 (2005) 321-331
-
(2005)
J Exp Med
, vol.202
, pp. 321-331
-
-
Christensen, S.R.1
Kashgarian, M.2
Alexopoulou, L.3
Flavell, R.A.4
Akira, S.5
Shlomchik, M.J.6
-
28
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
Christensen S.R., Shupe J., Nickerson K., Kashgarian M., Flavell R.A., and Shlomchik M.J. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25 (2006) 417-428
-
(2006)
Immunity
, vol.25
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, R.A.5
Shlomchik, M.J.6
-
29
-
-
33645076274
-
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
-
Ehlers M., Fukuyama H., McGaha T.L., Aderem A., and Ravetch J.V. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. J Exp Med 203 (2006) 553-561
-
(2006)
J Exp Med
, vol.203
, pp. 553-561
-
-
Ehlers, M.1
Fukuyama, H.2
McGaha, T.L.3
Aderem, A.4
Ravetch, J.V.5
-
30
-
-
33745864016
-
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus
-
Lartigue A., Courville P., Auquit I., Francois A., Arnoult C., Tron F., Gilbert D., and Musette P. Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus. J Immunol 177 (2006) 1349-1354
-
(2006)
J Immunol
, vol.177
, pp. 1349-1354
-
-
Lartigue, A.1
Courville, P.2
Auquit, I.3
Francois, A.4
Arnoult, C.5
Tron, F.6
Gilbert, D.7
Musette, P.8
-
31
-
-
33748465308
-
Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE
-
Yu P., Wellmann U., Kunder S., Quintanilla-Martinez L., Jennen L., Dear N., Amann K., Bauer S., Winkler T.H., and Wagner H. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. Int Immunol 18 (2006) 1211-1219
-
(2006)
Int Immunol
, vol.18
, pp. 1211-1219
-
-
Yu, P.1
Wellmann, U.2
Kunder, S.3
Quintanilla-Martinez, L.4
Jennen, L.5
Dear, N.6
Amann, K.7
Bauer, S.8
Winkler, T.H.9
Wagner, H.10
-
32
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun P., Deane J.A., Difilippantonio M.J., Tarasenko T., Satterthwaite A.B., and Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312 (2006) 1669-1672
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
33
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
Subramanian S., Tus K., Li Q.Z., Wang A., Tian X.H., Zhou J., Liang C., Bartov G., McDaniel L.D., Zhou X.J., et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci U S A 103 (2006) 9970-9975
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.Z.3
Wang, A.4
Tian, X.H.5
Zhou, J.6
Liang, C.7
Bartov, G.8
McDaniel, L.D.9
Zhou, X.J.10
-
34
-
-
36048962438
-
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
-
Overexpression of TLR7 in BAC Tg mice resulted in anti-RNA autoantibodies and lupus-like disease, as well as a myeloproliferative syndrome, in B6 mice. This directly implicated TLR7 as sufficient to cause autoimmunity, if overexpressed.
-
Deane J.A., Pisitkun P., Barrett R.S., Feigenbaum L., Town T., Ward J.M., Flavell R.A., and Bolland S. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27 (2007) 801-810. Overexpression of TLR7 in BAC Tg mice resulted in anti-RNA autoantibodies and lupus-like disease, as well as a myeloproliferative syndrome, in B6 mice. This directly implicated TLR7 as sufficient to cause autoimmunity, if overexpressed.
-
(2007)
Immunity
, vol.27
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
Feigenbaum, L.4
Town, T.5
Ward, J.M.6
Flavell, R.A.7
Bolland, S.8
-
35
-
-
33748470505
-
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice
-
Berland R., Fernandez L., Kari E., Han J.H., Lomakin I., Akira S., Wortis H.H., Kearney J.F., Ucci A.A., and Imanishi-Kari T. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity 25 (2006) 429-440
-
(2006)
Immunity
, vol.25
, pp. 429-440
-
-
Berland, R.1
Fernandez, L.2
Kari, E.3
Han, J.H.4
Lomakin, I.5
Akira, S.6
Wortis, H.H.7
Kearney, J.F.8
Ucci, A.A.9
Imanishi-Kari, T.10
-
36
-
-
48749085121
-
T cell-independent and Toll-like receptor-dependent antigen-driven activation of autoreactive B cells
-
This paper demonstrated a B-cell-intrinsic requirement for TLR signals to activate the RF extrafollicular response to antichromatin ICs. Importantly, T cells were not required for this, but modified both the induced and spontaneous RF response. These results suggested the paradigm of TLR-dependent B cell initiation of autoimmunity.
-
Herlands R.A., Christensen S.R., Sweet R.A., Hershberg U., and Shlomchik M.J. T cell-independent and Toll-like receptor-dependent antigen-driven activation of autoreactive B cells. Immunity 29 (2008) 249-260. This paper demonstrated a B-cell-intrinsic requirement for TLR signals to activate the RF extrafollicular response to antichromatin ICs. Importantly, T cells were not required for this, but modified both the induced and spontaneous RF response. These results suggested the paradigm of TLR-dependent B cell initiation of autoimmunity.
-
(2008)
Immunity
, vol.29
, pp. 249-260
-
-
Herlands, R.A.1
Christensen, S.R.2
Sweet, R.A.3
Hershberg, U.4
Shlomchik, M.J.5
-
37
-
-
33947656512
-
Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors
-
Christensen S.R., and Shlomchik M.J. Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors. Semin Immunol 19 (2007) 11-23
-
(2007)
Semin Immunol
, vol.19
, pp. 11-23
-
-
Christensen, S.R.1
Shlomchik, M.J.2
-
38
-
-
0036753722
-
Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses
-
MacLennan I.C.M., and Vinuesa C.G. Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses. Immunity 17 (2002) 235-238
-
(2002)
Immunity
, vol.17
, pp. 235-238
-
-
MacLennan, I.C.M.1
Vinuesa, C.G.2
-
39
-
-
0033806822
-
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
-
Sze D.M., Toellner K.M., de Vinuesa C.G., Taylor D.R., and MacLennan I.C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J Exp Med 192 (2000) 813-822
-
(2000)
J Exp Med
, vol.192
, pp. 813-822
-
-
Sze, D.M.1
Toellner, K.M.2
de Vinuesa, C.G.3
Taylor, D.R.4
MacLennan, I.C.5
-
40
-
-
33751200937
-
Plasma cell differentiation in T-independent type 2 immune responses is independent of CD11c(high) dendritic cells
-
Hebel K., Griewank K., Inamine A., Chang H.D., Muller-Hilke B., Fillatreau S., Manz R.A., Radbruch A., and Jung S. Plasma cell differentiation in T-independent type 2 immune responses is independent of CD11c(high) dendritic cells. Eur J Immunol 36 (2006) 2912-2919
-
(2006)
Eur J Immunol
, vol.36
, pp. 2912-2919
-
-
Hebel, K.1
Griewank, K.2
Inamine, A.3
Chang, H.D.4
Muller-Hilke, B.5
Fillatreau, S.6
Manz, R.A.7
Radbruch, A.8
Jung, S.9
-
41
-
-
34249792362
-
Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production
-
Yasuda K., Richez C., Maciaszek J.W., Agrawal N., Akira S., Marshak-Rothstein A., and Rifkin I.R. Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production. J Immunol 178 (2007) 6876-6885
-
(2007)
J Immunol
, vol.178
, pp. 6876-6885
-
-
Yasuda, K.1
Richez, C.2
Maciaszek, J.W.3
Agrawal, N.4
Akira, S.5
Marshak-Rothstein, A.6
Rifkin, I.R.7
-
42
-
-
3042548183
-
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
-
Boule M.W., Broughton C., Mackay F., Akira S., Marshak-Rothstein A., and Rifkin I.R. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 199 (2004) 1631-1640
-
(2004)
J Exp Med
, vol.199
, pp. 1631-1640
-
-
Boule, M.W.1
Broughton, C.2
Mackay, F.3
Akira, S.4
Marshak-Rothstein, A.5
Rifkin, I.R.6
-
43
-
-
41849090456
-
IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
-
Thibault D.L., Chu A.D., Graham K.L., Balboni I., Lee L.Y., Kohlmoos C., Landrigan A., Higgins J.P., Tibshirani R., and Utz P.J. IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice. J Clin Invest 118 (2008) 1417-1426
-
(2008)
J Clin Invest
, vol.118
, pp. 1417-1426
-
-
Thibault, D.L.1
Chu, A.D.2
Graham, K.L.3
Balboni, I.4
Lee, L.Y.5
Kohlmoos, C.6
Landrigan, A.7
Higgins, J.P.8
Tibshirani, R.9
Utz, P.J.10
-
44
-
-
11144353781
-
Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help
-
Poeck H., Wagner M., Battiany J., Rothenfusser S., Wellisch D., Hornung V., Jahrsdorfer B., Giese T., Endres S., and Hartmann G. Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help. Blood 103 (2004) 3058-3064
-
(2004)
Blood
, vol.103
, pp. 3058-3064
-
-
Poeck, H.1
Wagner, M.2
Battiany, J.3
Rothenfusser, S.4
Wellisch, D.5
Hornung, V.6
Jahrsdorfer, B.7
Giese, T.8
Endres, S.9
Hartmann, G.10
-
45
-
-
33646027625
-
Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection
-
Coro E.S., Chang W.L.W., and Baumgarth N. Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection. J Immunol 176 (2006) 4343-4351
-
(2006)
J Immunol
, vol.176
, pp. 4343-4351
-
-
Coro, E.S.1
Chang, W.L.W.2
Baumgarth, N.3
-
46
-
-
68149126174
-
Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop
-
IFN-I signaling is shown to enhance autoreactive B cell responses by two distinct mechanisms, sensitization of BCR signaling and TLR7 upregulation, with immediate relevance to which Ags activate the B cells. This provides an important link between myeloid/innate activation and autoreactive B cell stimulation.
-
Green N.M., Laws A., Kiefer K., Busconi L., Kim Y.M., Brinkmann M.M., Trail E.H., Yasuda K., Christensen S.R., Shlomchik M.J., et al. Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop. J Immunol 183 (2009) 1569-1576. IFN-I signaling is shown to enhance autoreactive B cell responses by two distinct mechanisms, sensitization of BCR signaling and TLR7 upregulation, with immediate relevance to which Ags activate the B cells. This provides an important link between myeloid/innate activation and autoreactive B cell stimulation.
-
(2009)
J Immunol
, vol.183
, pp. 1569-1576
-
-
Green, N.M.1
Laws, A.2
Kiefer, K.3
Busconi, L.4
Kim, Y.M.5
Brinkmann, M.M.6
Trail, E.H.7
Yasuda, K.8
Christensen, S.R.9
Shlomchik, M.J.10
-
47
-
-
67249158956
-
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
-
Sancho D., Joffre O.P., Keller A.M., Rogers N.C., Martinez D., Hernanz-Falcon P., Rosewell I., and Reis e Sousa C. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458 (2009) 899-903
-
(2009)
Nature
, vol.458
, pp. 899-903
-
-
Sancho, D.1
Joffre, O.P.2
Keller, A.M.3
Rogers, N.C.4
Martinez, D.5
Hernanz-Falcon, P.6
Rosewell, I.7
Reis e Sousa, C.8
-
48
-
-
52549125928
-
Mincle is an ITAM-coupled activating receptor that senses damaged cells
-
Yamasaki S., Ishikawa E., Sakuma M., Hara H., Ogata K., and Saito T. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol 9 (2008) 1179-1188
-
(2008)
Nat Immunol
, vol.9
, pp. 1179-1188
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Hara, H.4
Ogata, K.5
Saito, T.6
-
49
-
-
0041832267
-
Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG
-
Bave U., Magnusson M., Eloranta M.L., Perers A., Alm G.V., and Ronnblom L. Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. J Immunol 171 (2003) 3296-3302
-
(2003)
J Immunol
, vol.171
, pp. 3296-3302
-
-
Bave, U.1
Magnusson, M.2
Eloranta, M.L.3
Perers, A.4
Alm, G.V.5
Ronnblom, L.6
-
50
-
-
85047693371
-
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
-
Means T.K., Latz E., Hayashi F., Murali M.R., Golenbock D.T., and Luster A.D. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J Clin Invest 115 (2005) 407-417
-
(2005)
J Clin Invest
, vol.115
, pp. 407-417
-
-
Means, T.K.1
Latz, E.2
Hayashi, F.3
Murali, M.R.4
Golenbock, D.T.5
Luster, A.D.6
-
51
-
-
33745133006
-
Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells
-
Qi H., Egen J.G., Huang A.Y., and Germain R.N. Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 312 (2006) 1672-1676
-
(2006)
Science
, vol.312
, pp. 1672-1676
-
-
Qi, H.1
Egen, J.G.2
Huang, A.Y.3
Germain, R.N.4
-
52
-
-
27744576801
-
Cell surface recycling of internalized antigen permits dendritic cell priming of B cells
-
Bergtold A., Desai D.D., Gavhane A., and Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity 23 (2005) 503-514
-
(2005)
Immunity
, vol.23
, pp. 503-514
-
-
Bergtold, A.1
Desai, D.D.2
Gavhane, A.3
Clynes, R.4
-
53
-
-
0036732753
-
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
-
Litinskiy M.B., Nardelli B., Hilbert D.M., He B., Schaffer A., Casali P., and Cerutti A. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 3 (2002) 822-829
-
(2002)
Nat Immunol
, vol.3
, pp. 822-829
-
-
Litinskiy, M.B.1
Nardelli, B.2
Hilbert, D.M.3
He, B.4
Schaffer, A.5
Casali, P.6
Cerutti, A.7
-
54
-
-
33846937311
-
TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
-
Heer A.K., Shamshiev A., Donda A., Uematsu S., Akira S., Kopf M., and Marsland B.J. TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J Immunol 178 (2007) 2182-2191
-
(2007)
J Immunol
, vol.178
, pp. 2182-2191
-
-
Heer, A.K.1
Shamshiev, A.2
Donda, A.3
Uematsu, S.4
Akira, S.5
Kopf, M.6
Marsland, B.J.7
-
55
-
-
34250205694
-
Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL
-
He B., Xu W., Santini P.A., Polydorides A.D., Chiu A., Estrella J., Shan M., Chadburn A., Villanacci V., Plebani A., et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 26 (2007) 812-826
-
(2007)
Immunity
, vol.26
, pp. 812-826
-
-
He, B.1
Xu, W.2
Santini, P.A.3
Polydorides, A.D.4
Chiu, A.5
Estrella, J.6
Shan, M.7
Chadburn, A.8
Villanacci, V.9
Plebani, A.10
-
56
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., and Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102 (2000) 553-563
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
57
-
-
71849086224
-
T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice
-
Activation of high affinity anti-DNA B cells on the permissive B6 background was surprisingly found not to require T cells for most of the effects, supporting the notion that in some settings breach of B cell tolerance can be a primary step.
-
Tsao P.Y., Jiao J., Ji M.Q., Cohen P.L., and Eisenberg R.A. T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice. J Immunol 181 (2008) 7770-7777. Activation of high affinity anti-DNA B cells on the permissive B6 background was surprisingly found not to require T cells for most of the effects, supporting the notion that in some settings breach of B cell tolerance can be a primary step.
-
(2008)
J Immunol
, vol.181
, pp. 7770-7777
-
-
Tsao, P.Y.1
Jiao, J.2
Ji, M.Q.3
Cohen, P.L.4
Eisenberg, R.A.5
-
58
-
-
34547772125
-
BAFF and MyD88 signals promote a lupuslike disease independent of T cells
-
Mice overexpressing BAFF get lupus-like autoimmunity. In this work, Groom et al. show that the syndrome does not require T cells, but does require MyD88, again implicating this pathway in a different autoimmune setting.
-
Groom J.R., Fletcher C.A., Walters S.N., Grey S.T., Watt S.V., Sweet M.J., Smyth M.J., Mackay C.R., and Mackay F. BAFF and MyD88 signals promote a lupuslike disease independent of T cells. J Exp Med 204 (2007) 1959-1971. Mice overexpressing BAFF get lupus-like autoimmunity. In this work, Groom et al. show that the syndrome does not require T cells, but does require MyD88, again implicating this pathway in a different autoimmune setting.
-
(2007)
J Exp Med
, vol.204
, pp. 1959-1971
-
-
Groom, J.R.1
Fletcher, C.A.2
Walters, S.N.3
Grey, S.T.4
Watt, S.V.5
Sweet, M.J.6
Smyth, M.J.7
Mackay, C.R.8
Mackay, F.9
-
59
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
Mackay F., Woodcock S.A., Lawton P., Ambrose C., Baetscher M., Schneider P., Tschopp J., and Browning J.L. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190 (1999) 1697-1710
-
(1999)
J Exp Med
, vol.190
, pp. 1697-1710
-
-
Mackay, F.1
Woodcock, S.A.2
Lawton, P.3
Ambrose, C.4
Baetscher, M.5
Schneider, P.6
Tschopp, J.7
Browning, J.L.8
-
60
-
-
1342342916
-
Editing Anti-DNA B cells by Vλx
-
Li Y., Louzoun Y., and Weigert M. Editing Anti-DNA B cells by Vλx. J Exp Med 199 (2004) 337-346
-
(2004)
J Exp Med
, vol.199
, pp. 337-346
-
-
Li, Y.1
Louzoun, Y.2
Weigert, M.3
-
61
-
-
33646864148
-
Development and selection of edited B cells in B6.56R mice
-
Sekiguchi D.R., Yunk L., Gary D., Charan D., Srivastava B., Allman D., Weigert M.G., and Prak E.T. Development and selection of edited B cells in B6.56R mice. J Immunol 176 (2006) 6879-6887
-
(2006)
J Immunol
, vol.176
, pp. 6879-6887
-
-
Sekiguchi, D.R.1
Yunk, L.2
Gary, D.3
Charan, D.4
Srivastava, B.5
Allman, D.6
Weigert, M.G.7
Prak, E.T.8
-
62
-
-
34248217030
-
Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection
-
Cunningham A.F., Gaspal F., Serre K., Mohr E., Henderson I.R., Scott-Tucker A., Kenny S.M., Khan M., Toellner K.M., Lane P.J., et al. Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection. J Immunol 178 (2007) 6200-6207
-
(2007)
J Immunol
, vol.178
, pp. 6200-6207
-
-
Cunningham, A.F.1
Gaspal, F.2
Serre, K.3
Mohr, E.4
Henderson, I.R.5
Scott-Tucker, A.6
Kenny, S.M.7
Khan, M.8
Toellner, K.M.9
Lane, P.J.10
-
63
-
-
65449118056
-
BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation
-
Using a defined system of antigen on particulate beads, with or without TL9 ligand CpG DNA, the authors demonstrated formally that BCR plus TLR9 ligation in vivo exclusively directs a robust extrafollicular plasmablast response, much as seen in the AM14 RF response.
-
Eckl-Dorna J., and Batista F.D. BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation. Blood 113 (2009) 3969-3977. Using a defined system of antigen on particulate beads, with or without TL9 ligand CpG DNA, the authors demonstrated formally that BCR plus TLR9 ligation in vivo exclusively directs a robust extrafollicular plasmablast response, much as seen in the AM14 RF response.
-
(2009)
Blood
, vol.113
, pp. 3969-3977
-
-
Eckl-Dorna, J.1
Batista, F.D.2
-
64
-
-
0028922074
-
Autoantibodies in the diagnosis of systemic rheumatic diseases
-
von Muhlen C.A., and Tan E.M. Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin Arthritis Rheum 24 (1995) 323-358
-
(1995)
Semin Arthritis Rheum
, vol.24
, pp. 323-358
-
-
von Muhlen, C.A.1
Tan, E.M.2
-
65
-
-
0023278475
-
Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4
-
Wofsy D., and Seaman W.E. Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4. J Immunol 138 (1987) 3247-3253
-
(1987)
J Immunol
, vol.138
, pp. 3247-3253
-
-
Wofsy, D.1
Seaman, W.E.2
-
66
-
-
0029939451
-
Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses
-
Ma J., Xu J., Madaio M.P., Peng Q., Zhang J., Grewal I.S., Flavell R.A., and Craft J. Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses. J Immunol 157 (1996) 417-426
-
(1996)
J Immunol
, vol.157
, pp. 417-426
-
-
Ma, J.1
Xu, J.2
Madaio, M.P.3
Peng, Q.4
Zhang, J.5
Grewal, I.S.6
Flavell, R.A.7
Craft, J.8
-
67
-
-
0030589323
-
Propagation and regulation of systemic autoimmunity by gammadelta T cells
-
Peng S.L., Madaio M.P., Hayday A.C., and Craft J. Propagation and regulation of systemic autoimmunity by gammadelta T cells. J Immunol 157 (1996) 5689-5698
-
(1996)
J Immunol
, vol.157
, pp. 5689-5698
-
-
Peng, S.L.1
Madaio, M.P.2
Hayday, A.C.3
Craft, J.4
-
68
-
-
0029968324
-
Murine lupus in the absence of alpha beta T cells
-
Peng S.L., Madaio M.P., Hughes D.P., Crispe I.N., Owen M.J., Wen L., Hayday A.C., and Craft J. Murine lupus in the absence of alpha beta T cells. J Immunol 156 (1996) 4041-4049
-
(1996)
J Immunol
, vol.156
, pp. 4041-4049
-
-
Peng, S.L.1
Madaio, M.P.2
Hughes, D.P.3
Crispe, I.N.4
Owen, M.J.5
Wen, L.6
Hayday, A.C.7
Craft, J.8
-
69
-
-
0031092710
-
Alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity
-
Peng S.L., McNiff J.M., Madaio M.P., Ma J., Owen M.J., Flavell R.A., Hayday A.C., and Craft J. Alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. J Immunol 158 (1997) 2464-2470
-
(1997)
J Immunol
, vol.158
, pp. 2464-2470
-
-
Peng, S.L.1
McNiff, J.M.2
Madaio, M.P.3
Ma, J.4
Owen, M.J.5
Flavell, R.A.6
Hayday, A.C.7
Craft, J.8
-
70
-
-
58149279490
-
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
-
This paper reports a detailed characterization of extrafollicular T cells and further implicates them in the direct bidirectional interaction with B cells at these sites, mediated by ICOS-ICOSL and IL-21.
-
Odegard J.M., Marks B.R., DiPlacido L.D., Poholek A.C., Kono D.H., Dong C., Flavell R.A., and Craft J. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med 205 (2008) 2873-2886. This paper reports a detailed characterization of extrafollicular T cells and further implicates them in the direct bidirectional interaction with B cells at these sites, mediated by ICOS-ICOSL and IL-21.
-
(2008)
J Exp Med
, vol.205
, pp. 2873-2886
-
-
Odegard, J.M.1
Marks, B.R.2
DiPlacido, L.D.3
Poholek, A.C.4
Kono, D.H.5
Dong, C.6
Flavell, R.A.7
Craft, J.8
-
71
-
-
0026593440
-
Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens
-
Eynon E.E., and Parker D.C. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J Exp Med 175 (1992) 131
-
(1992)
J Exp Med
, vol.175
, pp. 131
-
-
Eynon, E.E.1
Parker, D.C.2
-
72
-
-
0026451165
-
B cells turn off virgin but not memory T cells
-
Fuchs E.J., and Matzinger P. B cells turn off virgin but not memory T cells. Science 258 (1992) 1156
-
(1992)
Science
, vol.258
, pp. 1156
-
-
Fuchs, E.J.1
Matzinger, P.2
-
73
-
-
0029165192
-
Gene-targeted B-deficient mice reveal a critical role for B cells in the CD4 T cell response
-
Liu Y., Wu Y., Ramarathinam L., Guo Y., Huszar D., Trounstine M., and Zhao M. Gene-targeted B-deficient mice reveal a critical role for B cells in the CD4 T cell response. Int Immunol 7 (1995) 1353-1362
-
(1995)
Int Immunol
, vol.7
, pp. 1353-1362
-
-
Liu, Y.1
Wu, Y.2
Ramarathinam, L.3
Guo, Y.4
Huszar, D.5
Trounstine, M.6
Zhao, M.7
-
75
-
-
0026750296
-
Breaking T cell tolerance with foreign and self co-immunogens: a study of autoimmune B and T cell epitopes of cytochrome c
-
Mamula M.J., Lin R.-H., Janeway Jr. C.A., and Hardin J.A. Breaking T cell tolerance with foreign and self co-immunogens: a study of autoimmune B and T cell epitopes of cytochrome c. J Immunol 149 (1992) 789-795
-
(1992)
J Immunol
, vol.149
, pp. 789-795
-
-
Mamula, M.J.1
Lin, R.-H.2
Janeway Jr., C.A.3
Hardin, J.A.4
-
76
-
-
0028204119
-
B cells process and present lupus autoantigens that initiate autoimmune T cell responses
-
Mamula M.J., Fatenejad S., and Craft J. B cells process and present lupus autoantigens that initiate autoimmune T cell responses. J Immunol 152 (1994) 1453-1461
-
(1994)
J Immunol
, vol.152
, pp. 1453-1461
-
-
Mamula, M.J.1
Fatenejad, S.2
Craft, J.3
-
77
-
-
33749155438
-
B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation
-
Yan J., Harvey B.P., Gee R.J., Shlomchik M.J., and Mamula M.J. B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation. J Immunol 177 (2006) 4481-4487
-
(2006)
J Immunol
, vol.177
, pp. 4481-4487
-
-
Yan, J.1
Harvey, B.P.2
Gee, R.J.3
Shlomchik, M.J.4
Mamula, M.J.5
-
78
-
-
17444384215
-
B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner
-
Rodriguez-Pinto D., and Moreno J. B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner. Eur J Immunol 35 (2005) 1097-1105
-
(2005)
Eur J Immunol
, vol.35
, pp. 1097-1105
-
-
Rodriguez-Pinto, D.1
Moreno, J.2
|