Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry

Cell Death and Differentiation

Volumn 22, Issue 11, 2015, Pages 1775-1784

  Marathe, S ^a   Liu, S ^b   Brai, E ^a   Kaczarowski, M ^a   Alberi, L ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYCLIN E1; GLYCOGEN SYNTHASE KINASE 3; KAINIC ACID; MESSENGER RNA; MYC PROTEIN; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P110; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HEY 1; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3BETA; GSK3B PROTEIN, MOUSE; NOTCH RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL CYCLE S PHASE REENTRY; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EXCITOTOXICITY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENOTYPE; HIPPOCAMPAL NEURONAL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; ANIMAL; CELL CULTURE; CELL CYCLE; DEGENERATIVE DISEASE; DRUG EFFECTS; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE; CELLS, CULTURED; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KAINIC ACID; MICE; NEURODEGENERATIVE DISEASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84943199538     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.23     Document Type: Article

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