-
1
-
-
78751481791
-
Rb/E2F regulates expression of neogenin during neuronal migration
-
CrossRef Medline
-
Andrusiak MG, McClellan KA, Dugal-Tessier D, Julian LM, Rodrigues SP, Park DS, Kennedy TE, Slack RS (2011) Rb/E2F regulates expression of neogenin during neuronal migration. Mol Cell Biol 31:238-247. CrossRef Medline
-
(2011)
Mol Cell Biol
, vol.31
, pp. 238-247
-
-
Andrusiak, M.G.1
McClellan, K.A.2
Dugal-Tessier, D.3
Julian, L.M.4
Rodrigues, S.P.5
Park, D.S.6
Kennedy, T.E.7
Slack, R.S.8
-
2
-
-
33846619735
-
Bim is elevated in Alzheimer's disease neurons and is required for β-amyloidinduced neuronal apoptosis
-
CrossRef Medline
-
Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA (2007) Bim is elevated in Alzheimer's disease neurons and is required for β-amyloidinduced neuronal apoptosis. J Neurosci 27:893-900. CrossRef Medline
-
(2007)
J Neurosci
, vol.27
, pp. 893-900
-
-
Biswas, S.C.1
Shi, Y.2
Vonsattel, J.P.3
Leung, C.L.4
Troy, C.M.5
Greene, L.A.6
-
3
-
-
50149120366
-
Cellular mechanisms of tumour suppression by the retinoblastoma gene
-
CrossRef Medline
-
Burkhart DL, Sage J (2008) Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 8:671-682. CrossRef Medline
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 671-682
-
-
Burkhart, D.L.1
Sage, J.2
-
4
-
-
0033559609
-
Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity
-
CrossRef Medline
-
Callaghan DA, Dong L, Callaghan SM, Hou YX, Dagnino L, Slack RS (1999) Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity. Dev Biol 207:257-270. CrossRef Medline
-
(1999)
Dev Biol
, vol.207
, pp. 257-270
-
-
Callaghan, D.A.1
Dong, L.2
Callaghan, S.M.3
Hou, Y.X.4
Dagnino, L.5
Slack, R.S.6
-
5
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
CrossRef Medline
-
Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, te Riele H (1992) Requirement for a functional Rb-1 gene in murine development. Nature 359:328-330. CrossRef Medline
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
van Roon, M.3
van der Lugt, N.M.4
van der Valk, M.5
Hooper, M.L.6
Berns, A.7
te Riele, H.8
-
6
-
-
0037975570
-
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice
-
CrossRef Medline
-
de Bruin A, Wu L, Saavedra HI, Wilson P, Yang Y, Rosol TJ, Weinstein M, Robinson ML, Leone G (2003) Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A 100:6546-6551. CrossRef Medline
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6546-6551
-
-
de Bruin, A.1
Wu, L.2
Saavedra, H.I.3
Wilson, P.4
Yang, Y.5
Rosol, T.J.6
Weinstein, M.7
Robinson, M.L.8
Leone, G.9
-
7
-
-
34548356529
-
Inducible gene inactivation in neurons of the adult mouse forebrain
-
CrossRef Medline
-
Erdmann G, Schütz G, Berger S (2007) Inducible gene inactivation in neurons of the adult mouse forebrain. BMCNeurosci 8:63. CrossRef Medline
-
(2007)
BMCNeurosci
, vol.8
, pp. 63
-
-
Erdmann, G.1
Schütz, G.2
Berger, S.3
-
8
-
-
18444389748
-
Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development
-
CrossRef Medline
-
Ferguson KL, Vanderluit JL, Hébert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS (2002) Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. EMBO J 21:3337-3346. CrossRef Medline
-
(2002)
EMBO J
, vol.21
, pp. 3337-3346
-
-
Ferguson, K.L.1
Vanderluit, J.L.2
Hébert, J.M.3
McIntosh, W.C.4
Tibbo, E.5
Maclaurin, J.G.6
Park, D.S.7
Wallace, V.A.8
Vooijs, M.9
McConnell, S.K.10
Slack, R.S.11
-
9
-
-
0035889087
-
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
-
CrossRef Medline
-
Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS, Hakim A, Albert PR, Cecconi F, Helin K, Park DS, Slack RS (2001) APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J Cell Biol 155:207-216. CrossRef Medline
-
(2001)
J Cell Biol
, vol.155
, pp. 207-216
-
-
Fortin, A.1
Cregan, S.P.2
Maclaurin, J.G.3
Kushwaha, N.4
Hickman, E.S.5
Thompson, C.S.6
Hakim, A.7
Albert, P.R.8
Cecconi, F.9
Helin, K.10
Park, D.S.11
Slack, R.S.12
-
10
-
-
33947109561
-
Cell cycle molecules define a pathway required for neuron death in development and disease
-
CrossRef Medline
-
Greene LA, Liu DX, Troy CM, Biswas SC (2007) Cell cycle molecules define a pathway required for neuron death in development and disease. Biochim Biophys Acta 1772:392-401. CrossRef Medline
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 392-401
-
-
Greene, L.A.1
Liu, D.X.2
Troy, C.M.3
Biswas, S.C.4
-
11
-
-
0035576791
-
Inactivation of the retinoblastoma tumor suppressor induces apoptosis proteaseactivating factor-1 dependent and independent apoptotic pathways during embryogenesis
-
Medline
-
Guo Z, Yikang S, Yoshida H, Mak TW, Zacksenhaus E (2001) Inactivation of the retinoblastoma tumor suppressor induces apoptosis proteaseactivating factor-1 dependent and independent apoptotic pathways during embryogenesis. Cancer Res 61:8395-8400. Medline
-
(2001)
Cancer Res
, vol.61
, pp. 8395-8400
-
-
Guo, Z.1
Yikang, S.2
Yoshida, H.3
Mak, T.W.4
Zacksenhaus, E.5
-
12
-
-
34247508686
-
Cell cycle regulation in the postmitotic neuron: Oxymoron or new biology?
-
CrossRef Medline
-
Herrup K, Yang Y (2007) Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci 8:368-378. CrossRef Medline
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 368-378
-
-
Herrup, K.1
Yang, Y.2
-
13
-
-
1542305653
-
Up-regulation of Bcl-2 homology 3 (BH3)- only proteins by E2F1 mediates apoptosis
-
CrossRef Medline
-
Hershko T, Ginsberg D (2004) Up-regulation of Bcl-2 homology 3 (BH3)- only proteins by E2F1 mediates apoptosis. J Biol Chem 279:8627-8634. CrossRef Medline
-
(2004)
J Biol Chem
, vol.279
, pp. 8627-8634
-
-
Hershko, T.1
Ginsberg, D.2
-
14
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
CrossRef Medline
-
Huang da W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57. CrossRef Medline
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
da Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
15
-
-
12344280017
-
Summaries of Affymetrix GeneChip probe level data
-
CrossRef Medline
-
Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31:e15. CrossRef Medline
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Irizarry, R.A.1
Bolstad, B.M.2
Collin, F.3
Cope, L.M.4
Hobbs, B.5
Speed, T.P.6
-
16
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
CrossRef Medline
-
Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA (1992) Effects of an Rb mutation in the mouse. Nature 359:295-300. CrossRef Medline
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
17
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
CrossRef Medline
-
Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359:288-294. CrossRef Medline
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
Bradley, A.8
-
18
-
-
15444379011
-
Regulation of neuron survival and death by p130 and associated chromatin modifiers
-
CrossRef Medline
-
Liu DX, Nath N, Chellappan SP, Greene LA (2005) Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes Dev 19:719-732. CrossRef Medline
-
(2005)
Genes Dev
, vol.19
, pp. 719-732
-
-
Liu, D.X.1
Nath, N.2
Chellappan, S.P.3
Greene, L.A.4
-
19
-
-
0037305849
-
Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
-
CrossRef Medline
-
MacPherson D, Sage J, Crowley D, Trumpp A, Bronson RT, Jacks T (2003) Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol Cell Biol 23:1044-1053. CrossRef Medline
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1044-1053
-
-
Macpherson, D.1
Sage, J.2
Crowley, D.3
Trumpp, A.4
Bronson, R.T.5
Jacks, T.6
-
20
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
Medline
-
Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev 14: 994-1004. Medline
-
(2000)
Genes Dev
, vol.14
, pp. 994-1004
-
-
Marino, S.1
Vooijs, M.2
van der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
21
-
-
0035879071
-
Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage
-
Medline
-
Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS (2001) Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. J Neurosci 21:5017-5026. Medline
-
(2001)
J Neurosci
, vol.21
, pp. 5017-5026
-
-
Morris, E.J.1
Keramaris, E.2
Rideout, H.J.3
Slack, R.S.4
Dyson, N.J.5
Stefanis, L.6
Park, D.S.7
-
22
-
-
0031016498
-
G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecininduced neuronal apoptosis
-
Medline
-
Park DS, Morris EJ, Greene LA, Geller HM (1997a) G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecininduced neuronal apoptosis. J Neurosci 17:1256-1270. Medline
-
(1997)
J Neurosci
, vol.17
, pp. 1256-1270
-
-
Park, D.S.1
Morris, E.J.2
Greene, L.A.3
Geller, H.M.4
-
23
-
-
0030694346
-
Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons
-
Medline
-
Park DS, Levine B, Ferrari G, Greene LA (1997b) Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J Neurosci 17:8975-8983. Medline
-
(1997)
J Neurosci
, vol.17
, pp. 8975-8983
-
-
Park, D.S.1
Levine, B.2
Ferrari, G.3
Greene, L.A.4
-
24
-
-
0034192510
-
Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage
-
Medline
-
Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA (2000) Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. J Neurosci 20:3104-3114. Medline
-
(2000)
J Neurosci
, vol.20
, pp. 3104-3114
-
-
Park, D.S.1
Morris, E.J.2
Bremner, R.3
Keramaris, E.4
Padmanabhan, J.5
Rosenbaum, M.6
Shelanski, M.L.7
Geller, H.M.8
Greene, L.A.9
-
25
-
-
70349437076
-
P53 and E2f: Partners in life and death
-
CrossRef Medline
-
Polager S, Ginsberg D (2009) P53 and E2f: partners in life and death. Nat Rev Cancer 9:738-748. CrossRef Medline
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 738-748
-
-
Polager, S.1
Ginsberg, D.2
-
26
-
-
25444460165
-
Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo
-
CrossRef Medline
-
Rashidian J, Iyirhiaro G, Aleyasin H, Rios M, Vincent I, Callaghan S, Bland RJ, Slack RS, During MJ, Park DS (2005) Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proc Natl Acad Sci U S A 102:14080-14085. CrossRef Medline
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14080-14085
-
-
Rashidian, J.1
Iyirhiaro, G.2
Aleyasin, H.3
Rios, M.4
Vincent, I.5
Callaghan, S.6
Bland, R.J.7
Slack, R.S.8
During, M.J.9
Park, D.S.10
-
28
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
CrossRef Medline
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273:5858-5868. CrossRef Medline
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
29
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Medline
-
Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E, Borsovsky I, Liu Z, Vinsavich A, Trush V, et al (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34:374-378. Medline
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
Bhagabati, N.6
Braisted, J.7
Klapa, M.8
Currier, T.9
Thiagarajan, M.10
Sturn, A.11
Snuffin, M.12
Rezantsev, A.13
Popov, D.14
Ryltsov, A.15
Kostukovich, E.16
Borsovsky, I.17
Liu, Z.18
Vinsavich, A.19
Trush, V.20
more..
-
30
-
-
34548235820
-
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy
-
CrossRef Medline
-
Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF (2007) BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol 27:6229-6242. CrossRef Medline
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6229-6242
-
-
Tracy, K.1
Dibling, B.C.2
Spike, B.T.3
Knabb, J.R.4
Schumacker, P.5
Macleod, K.F.6
-
31
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
CrossRef Medline
-
Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121. CrossRef Medline
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
32
-
-
0030008768
-
Expression of dominantnegative mutant DP-1 blocks cell cycle progression in G1
-
Medline
-
Wu CL, Classon M, Dyson N, Harlow E (1996) Expression of dominantnegative mutant DP-1 blocks cell cycle progression in G1. Mol Cell Biol 16:3698-3706. Medline
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3698-3706
-
-
Wu, C.L.1
Classon, M.2
Dyson, N.3
Harlow, E.4
-
33
-
-
84862869411
-
Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons
-
CrossRef Medline
-
Yu Y, Ren QG, Zhang ZH, Zhou K, Yu ZY, Luo X, Wang W (2012) Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons. Neurochem Res 37:503-511. CrossRef Medline
-
(2012)
Neurochem Res
, vol.37
, pp. 503-511
-
-
Yu, Y.1
Ren, Q.G.2
Zhang, Z.H.3
Zhou, K.4
Yu, Z.Y.5
Luo, X.6
Wang, W.7
|