메뉴 건너뛰기




Volumn 32, Issue 42, 2012, Pages 14809-14814

The retinoblastoma protein is essential for survival of postmitotic neurons

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; KI 67 ANTIGEN; NEURON SPECIFIC NUCLEAR PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

EID: 84867616342     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1912-12.2012     Document Type: Article
Times cited : (41)

References (33)
  • 2
    • 33846619735 scopus 로고    scopus 로고
    • Bim is elevated in Alzheimer's disease neurons and is required for β-amyloidinduced neuronal apoptosis
    • CrossRef Medline
    • Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA (2007) Bim is elevated in Alzheimer's disease neurons and is required for β-amyloidinduced neuronal apoptosis. J Neurosci 27:893-900. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 893-900
    • Biswas, S.C.1    Shi, Y.2    Vonsattel, J.P.3    Leung, C.L.4    Troy, C.M.5    Greene, L.A.6
  • 3
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • CrossRef Medline
    • Burkhart DL, Sage J (2008) Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 8:671-682. CrossRef Medline
    • (2008) Nat Rev Cancer , vol.8 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 4
    • 0033559609 scopus 로고    scopus 로고
    • Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity
    • CrossRef Medline
    • Callaghan DA, Dong L, Callaghan SM, Hou YX, Dagnino L, Slack RS (1999) Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity. Dev Biol 207:257-270. CrossRef Medline
    • (1999) Dev Biol , vol.207 , pp. 257-270
    • Callaghan, D.A.1    Dong, L.2    Callaghan, S.M.3    Hou, Y.X.4    Dagnino, L.5    Slack, R.S.6
  • 7
    • 34548356529 scopus 로고    scopus 로고
    • Inducible gene inactivation in neurons of the adult mouse forebrain
    • CrossRef Medline
    • Erdmann G, Schütz G, Berger S (2007) Inducible gene inactivation in neurons of the adult mouse forebrain. BMCNeurosci 8:63. CrossRef Medline
    • (2007) BMCNeurosci , vol.8 , pp. 63
    • Erdmann, G.1    Schütz, G.2    Berger, S.3
  • 10
    • 33947109561 scopus 로고    scopus 로고
    • Cell cycle molecules define a pathway required for neuron death in development and disease
    • CrossRef Medline
    • Greene LA, Liu DX, Troy CM, Biswas SC (2007) Cell cycle molecules define a pathway required for neuron death in development and disease. Biochim Biophys Acta 1772:392-401. CrossRef Medline
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 392-401
    • Greene, L.A.1    Liu, D.X.2    Troy, C.M.3    Biswas, S.C.4
  • 11
    • 0035576791 scopus 로고    scopus 로고
    • Inactivation of the retinoblastoma tumor suppressor induces apoptosis proteaseactivating factor-1 dependent and independent apoptotic pathways during embryogenesis
    • Medline
    • Guo Z, Yikang S, Yoshida H, Mak TW, Zacksenhaus E (2001) Inactivation of the retinoblastoma tumor suppressor induces apoptosis proteaseactivating factor-1 dependent and independent apoptotic pathways during embryogenesis. Cancer Res 61:8395-8400. Medline
    • (2001) Cancer Res , vol.61 , pp. 8395-8400
    • Guo, Z.1    Yikang, S.2    Yoshida, H.3    Mak, T.W.4    Zacksenhaus, E.5
  • 12
    • 34247508686 scopus 로고    scopus 로고
    • Cell cycle regulation in the postmitotic neuron: Oxymoron or new biology?
    • CrossRef Medline
    • Herrup K, Yang Y (2007) Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci 8:368-378. CrossRef Medline
    • (2007) Nat Rev Neurosci , vol.8 , pp. 368-378
    • Herrup, K.1    Yang, Y.2
  • 13
    • 1542305653 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 homology 3 (BH3)- only proteins by E2F1 mediates apoptosis
    • CrossRef Medline
    • Hershko T, Ginsberg D (2004) Up-regulation of Bcl-2 homology 3 (BH3)- only proteins by E2F1 mediates apoptosis. J Biol Chem 279:8627-8634. CrossRef Medline
    • (2004) J Biol Chem , vol.279 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 14
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • CrossRef Medline
    • Huang da W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57. CrossRef Medline
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 17
    • 0026744563 scopus 로고
    • Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
    • CrossRef Medline
    • Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359:288-294. CrossRef Medline
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.1    Chang, C.Y.2    Hu, N.3    Wang, Y.C.4    Lai, C.C.5    Herrup, K.6    Lee, W.H.7    Bradley, A.8
  • 18
    • 15444379011 scopus 로고    scopus 로고
    • Regulation of neuron survival and death by p130 and associated chromatin modifiers
    • CrossRef Medline
    • Liu DX, Nath N, Chellappan SP, Greene LA (2005) Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes Dev 19:719-732. CrossRef Medline
    • (2005) Genes Dev , vol.19 , pp. 719-732
    • Liu, D.X.1    Nath, N.2    Chellappan, S.P.3    Greene, L.A.4
  • 19
    • 0037305849 scopus 로고    scopus 로고
    • Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
    • CrossRef Medline
    • MacPherson D, Sage J, Crowley D, Trumpp A, Bronson RT, Jacks T (2003) Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol Cell Biol 23:1044-1053. CrossRef Medline
    • (2003) Mol Cell Biol , vol.23 , pp. 1044-1053
    • Macpherson, D.1    Sage, J.2    Crowley, D.3    Trumpp, A.4    Bronson, R.T.5    Jacks, T.6
  • 20
    • 0034656212 scopus 로고    scopus 로고
    • Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
    • Medline
    • Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev 14: 994-1004. Medline
    • (2000) Genes Dev , vol.14 , pp. 994-1004
    • Marino, S.1    Vooijs, M.2    van der Gulden, H.3    Jonkers, J.4    Berns, A.5
  • 21
    • 0035879071 scopus 로고    scopus 로고
    • Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage
    • Medline
    • Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS (2001) Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. J Neurosci 21:5017-5026. Medline
    • (2001) J Neurosci , vol.21 , pp. 5017-5026
    • Morris, E.J.1    Keramaris, E.2    Rideout, H.J.3    Slack, R.S.4    Dyson, N.J.5    Stefanis, L.6    Park, D.S.7
  • 22
    • 0031016498 scopus 로고    scopus 로고
    • G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecininduced neuronal apoptosis
    • Medline
    • Park DS, Morris EJ, Greene LA, Geller HM (1997a) G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecininduced neuronal apoptosis. J Neurosci 17:1256-1270. Medline
    • (1997) J Neurosci , vol.17 , pp. 1256-1270
    • Park, D.S.1    Morris, E.J.2    Greene, L.A.3    Geller, H.M.4
  • 23
    • 0030694346 scopus 로고    scopus 로고
    • Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons
    • Medline
    • Park DS, Levine B, Ferrari G, Greene LA (1997b) Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J Neurosci 17:8975-8983. Medline
    • (1997) J Neurosci , vol.17 , pp. 8975-8983
    • Park, D.S.1    Levine, B.2    Ferrari, G.3    Greene, L.A.4
  • 25
    • 70349437076 scopus 로고    scopus 로고
    • P53 and E2f: Partners in life and death
    • CrossRef Medline
    • Polager S, Ginsberg D (2009) P53 and E2f: partners in life and death. Nat Rev Cancer 9:738-748. CrossRef Medline
    • (2009) Nat Rev Cancer , vol.9 , pp. 738-748
    • Polager, S.1    Ginsberg, D.2
  • 28
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • CrossRef Medline
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273:5858-5868. CrossRef Medline
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 31
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • CrossRef Medline
    • Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121. CrossRef Medline
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 32
    • 0030008768 scopus 로고    scopus 로고
    • Expression of dominantnegative mutant DP-1 blocks cell cycle progression in G1
    • Medline
    • Wu CL, Classon M, Dyson N, Harlow E (1996) Expression of dominantnegative mutant DP-1 blocks cell cycle progression in G1. Mol Cell Biol 16:3698-3706. Medline
    • (1996) Mol Cell Biol , vol.16 , pp. 3698-3706
    • Wu, C.L.1    Classon, M.2    Dyson, N.3    Harlow, E.4
  • 33
    • 84862869411 scopus 로고    scopus 로고
    • Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons
    • CrossRef Medline
    • Yu Y, Ren QG, Zhang ZH, Zhou K, Yu ZY, Luo X, Wang W (2012) Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons. Neurochem Res 37:503-511. CrossRef Medline
    • (2012) Neurochem Res , vol.37 , pp. 503-511
    • Yu, Y.1    Ren, Q.G.2    Zhang, Z.H.3    Zhou, K.4    Yu, Z.Y.5    Luo, X.6    Wang, W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.