AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF

Journal of Biological Chemistry

Volumn 285, Issue 46, 2010, Pages 36199-36206

  Kilbride, Seán M ^a   Farrelly, Angela M ^b   Bonner, Caroline ^a   Ward, Manus W ^a   Nyhan, Kristine C ^b   Concannon, Caoimhín G ^a   Wollheim, Claes B ^c   Byrne, Maria M ^b   Prehn, Jochen H M ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; APOPTOSIS; APOPTOTIC; ATP LEVEL; BETA CELL; BIOENERGETIC RESPONSE; CARBOXAMIDES; FLUORESCENT MICROSCOPY; GENE EXPRESSION ANALYSIS; GENE SILENCING; HEPATOCYTE NUCLEAR FACTOR 1; HOMOLOGY DOMAIN; INDUCED APOPTOSIS; MODIFYING FACTORS; OVER-EXPRESSION; RIBONUCLEOTIDES; SINGLE CELLS; STRESS SENSOR; TRANSCRIPTIONAL ACTIVATIONS; TRANSGENIC MICE;

BIOCHEMISTRY; CELL DEATH; ENZYME ACTIVITY; FLOW CYTOMETRY; GENETIC ENGINEERING; GLUCOSE; PHYSIOLOGY; PROTEINS; SENSORS;

GENE EXPRESSION;

ADENOSINE TRIPHOSPHATE; BH3 PROTEIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOENERGETIC STRESS; CELL ENERGY; CELL STRESS; CONTROLLED STUDY; INSULIN RELEASE; MATURITY ONSET DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSCRIPTION INITIATION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DOXYCYCLINE; ENERGY METABOLISM; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HYPOGLYCEMIC AGENTS; INSULINOMA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN SUBUNITS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEOTIDES; RNA INTERFERENCE;

MUS MUSCULUS;

EID: 78149250620     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.138107     Document Type: Article

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