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Volumn 25, Issue 6, 2013, Pages 780-785

Mitosis and apoptosis: How is the balance set?

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; PROTEIN BCL 2; PROTEIN MCL 1;

EID: 84887624646     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.07.003     Document Type: Review
Times cited : (150)

References (46)
  • 1
    • 69549120405 scopus 로고    scopus 로고
    • How do anti-mitotic drugs kill cancer cells?
    • Gascoigne K.E., Taylor S.S. How do anti-mitotic drugs kill cancer cells?. J Cell Sci 2009, 122:2579-2585.
    • (2009) J Cell Sci , vol.122 , pp. 2579-2585
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 2
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan M.A., Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004, 4:253-265.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 3
    • 68549120912 scopus 로고    scopus 로고
    • Mitotic drivers-inhibitors of the Aurora B Kinase
    • Keen N., Taylor S. Mitotic drivers-inhibitors of the Aurora B Kinase. Cancer Metastasis Rev 2009, 28:185-195.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 185-195
    • Keen, N.1    Taylor, S.2
  • 5
    • 84855405497 scopus 로고    scopus 로고
    • The proliferation rate paradox in antimitotic chemotherapy
    • Mitchison T.J. The proliferation rate paradox in antimitotic chemotherapy. Mol Biol Cell 2012, 23:1-6.
    • (2012) Mol Biol Cell , vol.23 , pp. 1-6
    • Mitchison, T.J.1
  • 6
    • 22344446208 scopus 로고    scopus 로고
    • Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
    • Marty M., Cognetti F., Maraninchi D., Snyder R., Mauriac L., Tubiana-Hulin M., Chan S., Grimes D., Anton A., Lluch A., et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. J Clin Oncol 2005, 23:4265-4274.
    • (2005) J Clin Oncol , vol.23 , pp. 4265-4274
    • Marty, M.1    Cognetti, F.2    Maraninchi, D.3    Snyder, R.4    Mauriac, L.5    Tubiana-Hulin, M.6    Chan, S.7    Grimes, D.8    Anton, A.9    Lluch, A.10
  • 11
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
    • Gascoigne K.E., Taylor S.S. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008, 14:111-122.
    • (2008) Cancer Cell , vol.14 , pp. 111-122
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 12
    • 7744233719 scopus 로고    scopus 로고
    • Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint
    • Rieder C.L., Maiato H. Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev Cell 2004, 7:637-651.
    • (2004) Dev Cell , vol.7 , pp. 637-651
    • Rieder, C.L.1    Maiato, H.2
  • 13
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • Brito D.A., Rieder C.L. Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr Biol 2006, 16:1194-1200.
    • (2006) Curr Biol , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 14
    • 67749147567 scopus 로고    scopus 로고
    • The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS HeLa) cells
    • Brito D.A., Rieder C.L. The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS HeLa) cells. Cell Motil Cytoskeleton 2009, 66:437-447.
    • (2009) Cell Motil Cytoskeleton , vol.66 , pp. 437-447
    • Brito, D.A.1    Rieder, C.L.2
  • 15
    • 56249107716 scopus 로고    scopus 로고
    • Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
    • Orth J.D., Tang Y., Shi J., Loy C.T., Amendt C., Wilm C., Zenke F.T., Mitchison T.J. Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther 2008, 7:3480-3489.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3480-3489
    • Orth, J.D.1    Tang, Y.2    Shi, J.3    Loy, C.T.4    Amendt, C.5    Wilm, C.6    Zenke, F.T.7    Mitchison, T.J.8
  • 16
    • 44849127993 scopus 로고    scopus 로고
    • Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5
    • Shi J., Orth J.D., Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008, 68:3269-3276.
    • (2008) Cancer Res , vol.68 , pp. 3269-3276
    • Shi, J.1    Orth, J.D.2    Mitchison, T.3
  • 17
    • 70349452101 scopus 로고    scopus 로고
    • Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly
    • Huang H.-C., Shi J., Orth J.D., Mitchison T.J. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 2009, 16:347-358.
    • (2009) Cancer Cell , vol.16 , pp. 347-358
    • Huang, H.-C.1    Shi, J.2    Orth, J.D.3    Mitchison, T.J.4
  • 18
    • 84869054115 scopus 로고    scopus 로고
    • Cyclin dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phospho-regulation of anti-apoptotic Bcl-2 proteins
    • Sakurikar N., Eichhorn J.M., Chambers T.C. Cyclin dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phospho-regulation of anti-apoptotic Bcl-2 proteins. J Biol Chem 2012, 287:39193-39204.
    • (2012) J Biol Chem , vol.287 , pp. 39193-39204
    • Sakurikar, N.1    Eichhorn, J.M.2    Chambers, T.C.3
  • 19
    • 78650992174 scopus 로고    scopus 로고
    • Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest
    • Huang H.-C., Mitchison T.J., Shi J. Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest. PLoS ONE 2010, 5:e15724.
    • (2010) PLoS ONE , vol.5
    • Huang, H.-C.1    Mitchison, T.J.2    Shi, J.3
  • 20
    • 79960300023 scopus 로고    scopus 로고
    • Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells
    • Lee K., Kenny A.E., Rieder C.L. Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells. Mol Biol Cell 2011, 22:2470-2479.
    • (2011) Mol Biol Cell , vol.22 , pp. 2470-2479
    • Lee, K.1    Kenny, A.E.2    Rieder, C.L.3
  • 21
    • 34249828179 scopus 로고    scopus 로고
    • Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
    • Swanton C., Marani M., Pardo O., Warne P.H., Kelly G., Sahai E., Elustondo F., Chang J., Temple J., Ahmed A.A., et al. Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs. Cancer Cell 2007, 11:498-512.
    • (2007) Cancer Cell , vol.11 , pp. 498-512
    • Swanton, C.1    Marani, M.2    Pardo, O.3    Warne, P.H.4    Kelly, G.5    Sahai, E.6    Elustondo, F.7    Chang, J.8    Temple, J.9    Ahmed, A.A.10
  • 22
    • 0030687987 scopus 로고    scopus 로고
    • Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
    • Taylor S.S., McKeon F. Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell 1997, 89:727-735.
    • (1997) Cell , vol.89 , pp. 727-735
    • Taylor, S.S.1    McKeon, F.2
  • 24
    • 0020401629 scopus 로고
    • Mitosis in a cell with multiple centrioles
    • Ring D., Hubble R., Kirschner M. Mitosis in a cell with multiple centrioles. J Cell Biol 1982, 94:549-556.
    • (1982) J Cell Biol , vol.94 , pp. 549-556
    • Ring, D.1    Hubble, R.2    Kirschner, M.3
  • 25
    • 34247232176 scopus 로고    scopus 로고
    • Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis
    • Allan L.A., Clarke P.R. Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis. Mol Cell 2007, 26:301-310.
    • (2007) Mol Cell , vol.26 , pp. 301-310
    • Allan, L.A.1    Clarke, P.R.2
  • 27
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: outer membrane permeabilization and beyond
    • Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 2010, 11:621-632.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 28
    • 77954884045 scopus 로고    scopus 로고
    • Phosphorylation of Mcl-1 by CDK1/cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest
    • Harley M.E., Allan L.A., Sanderson H.S., Clarke P.R. Phosphorylation of Mcl-1 by CDK1/cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. EMBO J 2010, 29:2407-2420.
    • (2010) EMBO J , vol.29 , pp. 2407-2420
    • Harley, M.E.1    Allan, L.A.2    Sanderson, H.S.3    Clarke, P.R.4
  • 30
    • 84876475662 scopus 로고    scopus 로고
    • Programming cancer cells for high expression levels of Mcl1
    • Ertel F., Nguyen M., Roulston A., Shore G.C. Programming cancer cells for high expression levels of Mcl1. EMBO Rep 2013, 14:328-336.
    • (2013) EMBO Rep , vol.14 , pp. 328-336
    • Ertel, F.1    Nguyen, M.2    Roulston, A.3    Shore, G.C.4
  • 31
    • 21244472965 scopus 로고    scopus 로고
    • Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
    • Zhong Q., Gao W., Du F., Wang X. Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 2005, 121:1085-1095.
    • (2005) Cell , vol.121 , pp. 1085-1095
    • Zhong, Q.1    Gao, W.2    Du, F.3    Wang, X.4
  • 32
    • 34347350211 scopus 로고    scopus 로고
    • Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization
    • Ding Q., He X., Hsu J.M., Xia W., Chen C.T., Li L.Y., Lee D.F., Liu J.C., Zhong Q., Wang X., et al. Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol 2007, 27:4006-4017.
    • (2007) Mol Cell Biol , vol.27 , pp. 4006-4017
    • Ding, Q.1    He, X.2    Hsu, J.M.3    Xia, W.4    Chen, C.T.5    Li, L.Y.6    Lee, D.F.7    Liu, J.C.8    Zhong, Q.9    Wang, X.10
  • 34
    • 83955161188 scopus 로고    scopus 로고
    • Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration
    • Chu R., Terrano D.T., Chambers T.C. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem Pharmacol 2012, 83:199-206.
    • (2012) Biochem Pharmacol , vol.83 , pp. 199-206
    • Chu, R.1    Terrano, D.T.2    Chambers, T.C.3
  • 35
    • 84858983723 scopus 로고    scopus 로고
    • Up-regulation of pro-apoptotic Bim and down-regulation of anti-apoptotic Mcl-1 cooperatively mediate the enhanced tumor cell death induced by the combination of a MEK inhibitor and a microtubule inhibitor
    • Kawabata T., Tanimura S., Asai K., Kawasaki R., Matsumaru Y., Kohno M. Up-regulation of pro-apoptotic Bim and down-regulation of anti-apoptotic Mcl-1 cooperatively mediate the enhanced tumor cell death induced by the combination of a MEK inhibitor and a microtubule inhibitor. J Biol Chem 2012, 287:10289-10300.
    • (2012) J Biol Chem , vol.287 , pp. 10289-10300
    • Kawabata, T.1    Tanimura, S.2    Asai, K.3    Kawasaki, R.4    Matsumaru, Y.5    Kohno, M.6
  • 36
    • 79959886892 scopus 로고    scopus 로고
    • Navitoclax (ABT-263) Accelerates Apoptosis during Drug-Induced Mitotic Arrest by Antagonizing Bcl-xL
    • Shi J., Zhou Y., Huang H.-C., Mitchison T.J. Navitoclax (ABT-263) Accelerates Apoptosis during Drug-Induced Mitotic Arrest by Antagonizing Bcl-xL. Cancer Res 2011, 71:4518-4526.
    • (2011) Cancer Res , vol.71 , pp. 4518-4526
    • Shi, J.1    Zhou, Y.2    Huang, H.-C.3    Mitchison, T.J.4
  • 37
    • 77954615559 scopus 로고    scopus 로고
    • Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520
    • Tunquist B.J., Woessner R.D., Walker D.H. Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520. Mol Cancer Ther 2010, 9:2046-2056.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2046-2056
    • Tunquist, B.J.1    Woessner, R.D.2    Walker, D.H.3
  • 38
    • 18344386695 scopus 로고    scopus 로고
    • SCF-mediated protein degradation and cell cycle control
    • Ang X.L., Wade H.J. SCF-mediated protein degradation and cell cycle control. Oncogene 2005, 24:2860-2870.
    • (2005) Oncogene , vol.24 , pp. 2860-2870
    • Ang, X.L.1    Wade, H.J.2
  • 39
    • 75149132946 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis
    • Terrano D.T., Upreti M., Chambers T.C. Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis. Mol Cell Biol 2010, 30:640-656.
    • (2010) Mol Cell Biol , vol.30 , pp. 640-656
    • Terrano, D.T.1    Upreti, M.2    Chambers, T.C.3
  • 40
    • 58149090998 scopus 로고    scopus 로고
    • Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance
    • Upreti M., Galitovskaya E.N., Chu R., Tackett A.J., Terrano D.T., Granell S., Chambers T.C. Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. J Biol Chem 2008, 283:35517-35525.
    • (2008) J Biol Chem , vol.283 , pp. 35517-35525
    • Upreti, M.1    Galitovskaya, E.N.2    Chu, R.3    Tackett, A.J.4    Terrano, D.T.5    Granell, S.6    Chambers, T.C.7
  • 44
    • 79961127378 scopus 로고    scopus 로고
    • Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells
    • Tang Y., Orth J.D., Xie T., Mitchison T.J. Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer Lett 2011, 310:15-24.
    • (2011) Cancer Lett , vol.310 , pp. 15-24
    • Tang, Y.1    Orth, J.D.2    Xie, T.3    Mitchison, T.J.4
  • 45
    • 14944349359 scopus 로고    scopus 로고
    • Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim
    • Li R., Moudgil T., Ross H.J., Hu H.M. Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. Cell Death Differ 2005, 12:292-303.
    • (2005) Cell Death Differ , vol.12 , pp. 292-303
    • Li, R.1    Moudgil, T.2    Ross, H.J.3    Hu, H.M.4
  • 46
    • 77956710766 scopus 로고    scopus 로고
    • Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells
    • Kutuk O., Letai A. Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells. Cell Death Differ 2010, 17:1624-1635.
    • (2010) Cell Death Differ , vol.17 , pp. 1624-1635
    • Kutuk, O.1    Letai, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.