메뉴 건너뛰기




Volumn 18, Issue , 2015, Pages 968-985

Carotenoids modulate the hallmarks of cancer cells

Author keywords

Anti angiogenesis; Anti metastasis; Apoptosis; Carotenoids; Cell cycle arrest; Epidemiology

Indexed keywords


EID: 84942537006     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2014.10.017     Document Type: Article
Times cited : (94)

References (173)
  • 1
    • 84931323793 scopus 로고    scopus 로고
    • Role of dietary antioxidants in cancer
    • Springer, USA, S. Shankar, R.K. Srivastava (Eds.)
    • Ajila C., Brar S. Role of dietary antioxidants in cancer. Nutrition, diet and cancer 2012, 377-412. Springer, USA. S. Shankar, R.K. Srivastava (Eds.).
    • (2012) Nutrition, diet and cancer , pp. 377-412
    • Ajila, C.1    Brar, S.2
  • 3
    • 0033008852 scopus 로고    scopus 로고
    • Lycopene and 1, 25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells
    • Amir H., Karas M., Giat J., Danilenko M., Levy R., Yermiahu T., Levy J., Sharoni Y. Lycopene and 1, 25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells. Nutrition and Cancer 1999, 33:105-112.
    • (1999) Nutrition and Cancer , vol.33 , pp. 105-112
    • Amir, H.1    Karas, M.2    Giat, J.3    Danilenko, M.4    Levy, R.5    Yermiahu, T.6    Levy, J.7    Sharoni, Y.8
  • 9
    • 80055066234 scopus 로고    scopus 로고
    • Carotenoids in nature: Insights from plants and beyond
    • Cazzonelli C.I. Carotenoids in nature: Insights from plants and beyond. Functional Plant Biology 2011, 38:833-847.
    • (2011) Functional Plant Biology , vol.38 , pp. 833-847
    • Cazzonelli, C.I.1
  • 10
    • 0006920053 scopus 로고
    • Isolation of neoxanthin and its prevention on lipid peroxidation
    • Chang J.M., Lin J.K. Isolation of neoxanthin and its prevention on lipid peroxidation. Journal of Chinese Medicine 1993, 4:235-245.
    • (1993) Journal of Chinese Medicine , vol.4 , pp. 235-245
    • Chang, J.M.1    Lin, J.K.2
  • 12
    • 84860233467 scopus 로고    scopus 로고
    • Diverse effects of β-carotene on secretion and expression of VEGF in human hepatocarcinoma and prostate tumour cells
    • Chen H.Y., Huang S.M., Yang C.M., Hu M.L. Diverse effects of β-carotene on secretion and expression of VEGF in human hepatocarcinoma and prostate tumour cells. Molecules 2012, 17:3981-3988.
    • (2012) Molecules , vol.17 , pp. 3981-3988
    • Chen, H.Y.1    Huang, S.M.2    Yang, C.M.3    Hu, M.L.4
  • 13
    • 84887041126 scopus 로고    scopus 로고
    • Anti-metastatic effects of α-carotene and possible mechanisms of action in human hepatocarcinoma SK-Hep-1 cells
    • Chen H.Y., Yueh T.C., Chen Y.C., Huang C.H., Yang C.M., Hu M.L. Anti-metastatic effects of α-carotene and possible mechanisms of action in human hepatocarcinoma SK-Hep-1 cells. Journal of Agricultural and Food Chemistry 2013, 61:10368-10376.
    • (2013) Journal of Agricultural and Food Chemistry , vol.61 , pp. 10368-10376
    • Chen, H.Y.1    Yueh, T.C.2    Chen, Y.C.3    Huang, C.H.4    Yang, C.M.5    Hu, M.L.6
  • 14
    • 84862560347 scopus 로고    scopus 로고
    • Lycopene inhibits angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-Akt and ERK/p38 signaling pathways
    • Chen M.L., Lin Y.H., Yang C.M., Hu M.L. Lycopene inhibits angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-Akt and ERK/p38 signaling pathways. Molecular Nutrition and Food Research 2012, 56:889-899.
    • (2012) Molecular Nutrition and Food Research , vol.56 , pp. 889-899
    • Chen, M.L.1    Lin, Y.H.2    Yang, C.M.3    Hu, M.L.4
  • 15
    • 34548583396 scopus 로고    scopus 로고
    • Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models
    • Cheng H.C., Chien H., Liao C.H., Yang Y.Y., Huang S.Y. Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models. The Journal of Nutritional Biochemistry 2007, 18:667-675.
    • (2007) The Journal of Nutritional Biochemistry , vol.18 , pp. 667-675
    • Cheng, H.C.1    Chien, H.2    Liao, C.H.3    Yang, Y.Y.4    Huang, S.Y.5
  • 17
    • 0033884831 scopus 로고    scopus 로고
    • Effects of β-carotene supplementation on cancer incidence by baseline characteristics in the Physicians' Health Study (United States)
    • Cook N.R., Lee I.-M., Manson J.E., Buring J.E., Hennekens C.H. Effects of β-carotene supplementation on cancer incidence by baseline characteristics in the Physicians' Health Study (United States). Cancer Causes and Control 2000, 11:617-626.
    • (2000) Cancer Causes and Control , vol.11 , pp. 617-626
    • Cook, N.R.1    Lee, I.-M.2    Manson, J.E.3    Buring, J.E.4    Hennekens, C.H.5
  • 18
    • 36049032810 scopus 로고    scopus 로고
    • β-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells
    • Cui Y., Lu Z., Bai L., Shi Z., Zhao W.E., Zhao B. β-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells. European Journal of Cancer 2007, 43:2590-2601.
    • (2007) European Journal of Cancer , vol.43 , pp. 2590-2601
    • Cui, Y.1    Lu, Z.2    Bai, L.3    Shi, Z.4    Zhao, W.E.5    Zhao, B.6
  • 20
    • 40949104695 scopus 로고    scopus 로고
    • Growth inhibition of human hepatic carcinoma HepG2 cells by fucoxanthin is associated with down-regulation of cyclin D
    • Das S.K., Hashimoto T., Kanazawa K. Growth inhibition of human hepatic carcinoma HepG2 cells by fucoxanthin is associated with down-regulation of cyclin D. Biochimica et Biophysica Acta (BBA)-General Subjects 2008, 1780:743-749.
    • (2008) Biochimica et Biophysica Acta (BBA)-General Subjects , vol.1780 , pp. 743-749
    • Das, S.K.1    Hashimoto, T.2    Kanazawa, K.3
  • 26
    • 84865219359 scopus 로고    scopus 로고
    • Lycopene inhibits angiogenesis in human umbilical vein endothelial cells and rat aortic rings
    • Elgass S., Cooper A., Chopra M. Lycopene inhibits angiogenesis in human umbilical vein endothelial cells and rat aortic rings. British Journal of Nutrition 2012, 108:431-439.
    • (2012) British Journal of Nutrition , vol.108 , pp. 431-439
    • Elgass, S.1    Cooper, A.2    Chopra, M.3
  • 29
    • 79951864386 scopus 로고    scopus 로고
    • Lycopene and apo-12'-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells
    • Ford N.A., Elsen A.C., Zuniga K., Lindshield B.L., Erdman J.W. Lycopene and apo-12'-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells. Nutrition and Cancer 2011, 63:256-263.
    • (2011) Nutrition and Cancer , vol.63 , pp. 256-263
    • Ford, N.A.1    Elsen, A.C.2    Zuniga, K.3    Lindshield, B.L.4    Erdman, J.W.5
  • 30
  • 32
    • 84876395725 scopus 로고    scopus 로고
    • Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells
    • Ganesan P., Matsubara K., Sugawara T., Hirata T. Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells. Molecular and Cellular Biochemistry 2013, 380:1-9.
    • (2013) Molecular and Cellular Biochemistry , vol.380 , pp. 1-9
    • Ganesan, P.1    Matsubara, K.2    Sugawara, T.3    Hirata, T.4
  • 34
  • 38
    • 84899696166 scopus 로고    scopus 로고
    • Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines
    • Gloria N.F., Soares N., Brand C., Oliveira F.L., Borojevic R., Teodoro A.J. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Research 2014, 34:1377-1386.
    • (2014) Anticancer Research , vol.34 , pp. 1377-1386
    • Gloria, N.F.1    Soares, N.2    Brand, C.3    Oliveira, F.L.4    Borojevic, R.5    Teodoro, A.J.6
  • 39
    • 10644263516 scopus 로고    scopus 로고
    • The β-carotene and retinol efficacy trial: Incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping β-carotene and retinol supplements
    • Goodman G.E., Thornquist M.D., Balmes J., Cullen M.R., Meyskens F.L., Omenn G.S., Valanis B., Williams J.H. The β-carotene and retinol efficacy trial: Incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping β-carotene and retinol supplements. Journal of the National Cancer Institute 2004, 96:1743-1750.
    • (2004) Journal of the National Cancer Institute , vol.96 , pp. 1743-1750
    • Goodman, G.E.1    Thornquist, M.D.2    Balmes, J.3    Cullen, M.R.4    Meyskens, F.L.5    Omenn, G.S.6    Valanis, B.7    Williams, J.H.8
  • 41
    • 84857438453 scopus 로고    scopus 로고
    • Antioxidant activity of (all-E)-lycopene and synthetic apo-lycopenoids in a chemical model of oxidative stress in the gastro-intestinal tract
    • Goupy P., Reynaud E., Dangles O., Caris-Veyrat C. Antioxidant activity of (all-E)-lycopene and synthetic apo-lycopenoids in a chemical model of oxidative stress in the gastro-intestinal tract. New Journal of Chemistry 2012, 36:575-587.
    • (2012) New Journal of Chemistry , vol.36 , pp. 575-587
    • Goupy, P.1    Reynaud, E.2    Dangles, O.3    Caris-Veyrat, C.4
  • 42
    • 34548142633 scopus 로고    scopus 로고
    • β-carotene inhibits tumour-specific angiogenesis by altering the cytokine profile and inhibits the nuclear translocation of transcription factors in B16F-10 melanoma cells
    • Guruvayoorappan C., Kuttan G. β-carotene inhibits tumour-specific angiogenesis by altering the cytokine profile and inhibits the nuclear translocation of transcription factors in B16F-10 melanoma cells. Integrative Cancer Therapies 2007, 6:258-270.
    • (2007) Integrative Cancer Therapies , vol.6 , pp. 258-270
    • Guruvayoorappan, C.1    Kuttan, G.2
  • 45
    • 14344259481 scopus 로고    scopus 로고
    • Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells
    • Hantz H.L., Young L.F., Martin K.R. Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells. Experimental Biology and Medicine 2005, 230:171-179.
    • (2005) Experimental Biology and Medicine , vol.230 , pp. 171-179
    • Hantz, H.L.1    Young, L.F.2    Martin, K.R.3
  • 48
    • 7744240624 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis and enhances the anti-proliferative effect of the PPAR-γ ligand, troglitazone, on colon cancer cells
    • Hosokawa M., Kudo M., Maeda H., Kohno H., Tanaka T., Miyashita K. Fucoxanthin induces apoptosis and enhances the anti-proliferative effect of the PPAR-γ ligand, troglitazone, on colon cancer cells. Biochimica et Biophysica Acta 2004, 1675:113-119.
    • (2004) Biochimica et Biophysica Acta , vol.1675 , pp. 113-119
    • Hosokawa, M.1    Kudo, M.2    Maeda, H.3    Kohno, H.4    Tanaka, T.5    Miyashita, K.6
  • 49
    • 84872761474 scopus 로고    scopus 로고
    • Anti-angiogenic effects of lycopene through immunomodulation of cytokine secretion in human peripheral blood mononuclear cells
    • Huang C.S., Chuang C.H., Lo T.F., Hu M.L. Anti-angiogenic effects of lycopene through immunomodulation of cytokine secretion in human peripheral blood mononuclear cells. The Journal of Nutritional Biochemistry 2013, 24:428-434.
    • (2013) The Journal of Nutritional Biochemistry , vol.24 , pp. 428-434
    • Huang, C.S.1    Chuang, C.H.2    Lo, T.F.3    Hu, M.L.4
  • 50
    • 34249913180 scopus 로고    scopus 로고
    • Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1
    • Huang C.S., Fan Y.E., Lin C.Y., Hu M.L. Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1. The Journal of Nutritional Biochemistry 2007, 18:449-456.
    • (2007) The Journal of Nutritional Biochemistry , vol.18 , pp. 449-456
    • Huang, C.S.1    Fan, Y.E.2    Lin, C.Y.3    Hu, M.L.4
  • 51
    • 40449110427 scopus 로고    scopus 로고
    • Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice
    • Huang C.S., Liao J.W., Hu M.L. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. The Journal of Nutrition 2008, 138:538-543.
    • (2008) The Journal of Nutrition , vol.138 , pp. 538-543
    • Huang, C.S.1    Liao, J.W.2    Hu, M.L.3
  • 52
    • 24744436403 scopus 로고    scopus 로고
    • Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells
    • Huang C.S., Shih M.K., Chuang C.H., Hu M.L. Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells. The Journal of Nutrition 2005, 135:2119-2123.
    • (2005) The Journal of Nutrition , vol.135 , pp. 2119-2123
    • Huang, C.S.1    Shih, M.K.2    Chuang, C.H.3    Hu, M.L.4
  • 53
    • 4644325180 scopus 로고    scopus 로고
    • Cell cycle arrest and induction of apoptosis by lycopene in LNCaP human prostate cancer cells
    • Hwang E.S., Bowen P.E. Cell cycle arrest and induction of apoptosis by lycopene in LNCaP human prostate cancer cells. Journal of Medicinal Food 2004, 7:284-289.
    • (2004) Journal of Medicinal Food , vol.7 , pp. 284-289
    • Hwang, E.S.1    Bowen, P.E.2
  • 54
    • 33644671562 scopus 로고    scopus 로고
    • Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells
    • Hwang E.S., Lee H.J. Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells. Experimental Biology and Medicine 2006, 231:322-327.
    • (2006) Experimental Biology and Medicine , vol.231 , pp. 322-327
    • Hwang, E.S.1    Lee, H.J.2
  • 56
    • 33947590535 scopus 로고    scopus 로고
    • Lycopene differentially induces quiescence and apoptosis in androgen-responsive and-independent prostate cancer cell lines
    • Ivanov N.I., Cowell S.P., Brown P., Rennie P.S., Guns E.S., Cox M.E. Lycopene differentially induces quiescence and apoptosis in androgen-responsive and-independent prostate cancer cell lines. Clinical Nutrition 2007, 26:252-263.
    • (2007) Clinical Nutrition , vol.26 , pp. 252-263
    • Ivanov, N.I.1    Cowell, S.P.2    Brown, P.3    Rennie, P.S.4    Guns, E.S.5    Cox, M.E.6
  • 58
    • 69149103822 scopus 로고    scopus 로고
    • Mechanism of β-carotene-induced apoptosis of gastric cancer cells: Involvement of ataxia-telangiectasia-mutated
    • Jang S.H., Lim J.W., Kim H. Mechanism of β-carotene-induced apoptosis of gastric cancer cells: Involvement of ataxia-telangiectasia-mutated. Annals of the New York Academy of Sciences 2009, 1171:156-162.
    • (2009) Annals of the New York Academy of Sciences , vol.1171 , pp. 156-162
    • Jang, S.H.1    Lim, J.W.2    Kim, H.3
  • 59
    • 84855786408 scopus 로고    scopus 로고
    • Isolation of fucoxanthin and fatty acids analysis of Padina australis and cytotoxic effect of fucoxanthin on human lung cancer (H1299) cell lines
    • Jaswir I., Noviendri D., Salleh H.M., Taher M., Miyashita K. Isolation of fucoxanthin and fatty acids analysis of Padina australis and cytotoxic effect of fucoxanthin on human lung cancer (H1299) cell lines. African Journal of Biotechnology 2013, 10:18855-18862.
    • (2013) African Journal of Biotechnology , vol.10 , pp. 18855-18862
    • Jaswir, I.1    Noviendri, D.2    Salleh, H.M.3    Taher, M.4    Miyashita, K.5
  • 61
    • 84879478157 scopus 로고    scopus 로고
    • Astaxanthin inhibits NF-κB and Wnt/β-catenin signaling pathways via inactivation of ERK/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer
    • Kavitha K., Kowshik J., Kishore T., Baba A.B., Nagini S. Astaxanthin inhibits NF-κB and Wnt/β-catenin signaling pathways via inactivation of ERK/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer. Biochimica et Biophysica Acta (BBA)-General Subjects 2013, 1830:4433-4444.
    • (2013) Biochimica et Biophysica Acta (BBA)-General Subjects , vol.1830 , pp. 4433-4444
    • Kavitha, K.1    Kowshik, J.2    Kishore, T.3    Baba, A.B.4    Nagini, S.5
  • 62
  • 64
    • 77956181267 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway
    • Kim K.N., Heo S.J., Kang S.M., Ahn G., Jeon Y.J. Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. Toxicology In Vitro 2010, 24:1648-1654.
    • (2010) Toxicology In Vitro , vol.24 , pp. 1648-1654
    • Kim, K.N.1    Heo, S.J.2    Kang, S.M.3    Ahn, G.4    Jeon, Y.J.5
  • 65
    • 84946419019 scopus 로고    scopus 로고
    • The effect of β-carotene on migration and invasion in SK-N-BE (2) C neuroblastoma cells
    • 639.16
    • Kim Y.S., Lee H.A., Kim Y. The effect of β-carotene on migration and invasion in SK-N-BE (2) C neuroblastoma cells. The FASEB Journal 2013, 27:639.16.
    • (2013) The FASEB Journal , vol.27
    • Kim, Y.S.1    Lee, H.A.2    Kim, Y.3
  • 66
    • 84899929201 scopus 로고    scopus 로고
    • β-carotene inhibits neuroblastoma cell invasion and metastasis in vitro and in vivo by decreasing level of hypoxia-inducible factor-1α
    • Kim Y.S., Lee H.A., Lim J.Y., Kim Y., Jung C.H., Yoo S.H., Kim Y. β-carotene inhibits neuroblastoma cell invasion and metastasis in vitro and in vivo by decreasing level of hypoxia-inducible factor-1α. The Journal of Nutritional Biochemistry 2014, 25:655-664.
    • (2014) The Journal of Nutritional Biochemistry , vol.25 , pp. 655-664
    • Kim, Y.S.1    Lee, H.A.2    Lim, J.Y.3    Kim, Y.4    Jung, C.H.5    Yoo, S.H.6    Kim, Y.7
  • 68
    • 14644445985 scopus 로고    scopus 로고
    • Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells
    • Kotake-Nara E., Asai A., Nagao A. Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells. Cancer Letters 2005, 220:75-84.
    • (2005) Cancer Letters , vol.220 , pp. 75-84
    • Kotake-Nara, E.1    Asai, A.2    Nagao, A.3
  • 70
    • 15244357257 scopus 로고    scopus 로고
    • Characterization of apoptosis induced by fucoxanthin in human promyelocytic leukemia cells
    • Kotake-Nara E., Terasaki M., Nagao A. Characterization of apoptosis induced by fucoxanthin in human promyelocytic leukemia cells. Bioscience Biotechnology Biochemistry 2005, 69:224-227.
    • (2005) Bioscience Biotechnology Biochemistry , vol.69 , pp. 224-227
    • Kotake-Nara, E.1    Terasaki, M.2    Nagao, A.3
  • 71
    • 0034599893 scopus 로고    scopus 로고
    • Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture
    • Kozuki Y., Miura Y., Yagasaki K. Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture. Cancer Letters 2000, 151:111-115.
    • (2000) Cancer Letters , vol.151 , pp. 111-115
    • Kozuki, Y.1    Miura, Y.2    Yagasaki, K.3
  • 73
    • 84892419887 scopus 로고    scopus 로고
    • Fucoxanthin: A marine carotenoids exerting anti-cancer effects by affecting multiple mechanisms
    • Kumar S.A., Hosokawa M., Miyashita K. Fucoxanthin: A marine carotenoids exerting anti-cancer effects by affecting multiple mechanisms. Marine Drugs 2013, 11:5130-5147.
    • (2013) Marine Drugs , vol.11 , pp. 5130-5147
    • Kumar, S.A.1    Hosokawa, M.2    Miyashita, K.3
  • 74
    • 0037066403 scopus 로고    scopus 로고
    • Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress
    • Kurihara H., Koda H., Asami S., Kiso Y., Tanaka T. Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress. Life Sciences 2002, 70:2509-2520.
    • (2002) Life Sciences , vol.70 , pp. 2509-2520
    • Kurihara, H.1    Koda, H.2    Asami, S.3    Kiso, Y.4    Tanaka, T.5
  • 76
    • 33748873613 scopus 로고    scopus 로고
    • β-cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor-β expression
    • Lian F., Hu K.Q., Russell R.M., Wang X.D. β-cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor-β expression. International Journal of Cancer 2006, 119:2084-2089.
    • (2006) International Journal of Cancer , vol.119 , pp. 2084-2089
    • Lian, F.1    Hu, K.Q.2    Russell, R.M.3    Wang, X.D.4
  • 78
    • 80054995016 scopus 로고    scopus 로고
    • Cancer chemopreventive effects of lycopene: Suppression of MMP-7 expression and cell invasion in human colon cancer cells
    • Lin M.C., Wang F.Y., Kuo Y.H., Tang F.Y. Cancer chemopreventive effects of lycopene: Suppression of MMP-7 expression and cell invasion in human colon cancer cells. Journal of Agricultural and Food Chemistry 2011, 59:11304-11318.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , pp. 11304-11318
    • Lin, M.C.1    Wang, F.Y.2    Kuo, Y.H.3    Tang, F.Y.4
  • 79
    • 0022656975 scopus 로고
    • Tumour invasion and metastases-role of the extracellular matrix: Rhoads Memorial Award lecture
    • Liotta L.A. Tumour invasion and metastases-role of the extracellular matrix: Rhoads Memorial Award lecture. Cancer Research 1986, 46:1-7.
    • (1986) Cancer Research , vol.46 , pp. 1-7
    • Liotta, L.A.1
  • 80
    • 70350134708 scopus 로고    scopus 로고
    • Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication
    • Liu C.L., Huang Y.S., Hosokawa M., Miyashita K., Hu M.L. Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication. Chemico-Biological Interactions 2009, 182:165-172.
    • (2009) Chemico-Biological Interactions , vol.182 , pp. 165-172
    • Liu, C.L.1    Huang, Y.S.2    Hosokawa, M.3    Miyashita, K.4    Hu, M.L.5
  • 81
    • 0038407714 scopus 로고    scopus 로고
    • Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets
    • Liu C., Lian F., Smith D.E., Russell R.M., Wang X.D. Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Research 2003, 63:3138-3144.
    • (2003) Cancer Research , vol.63 , pp. 3138-3144
    • Liu, C.1    Lian, F.2    Smith, D.E.3    Russell, R.M.4    Wang, X.D.5
  • 82
    • 18744394900 scopus 로고    scopus 로고
    • Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumour cells
    • Livny O., Kaplan I., Reifen R., Polak-Charcon S., Madar Z., Schwartz B. Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumour cells. The Journal of Nutrition 2002, 132:3754-3759.
    • (2002) The Journal of Nutrition , vol.132 , pp. 3754-3759
    • Livny, O.1    Kaplan, I.2    Reifen, R.3    Polak-Charcon, S.4    Madar, Z.5    Schwartz, B.6
  • 83
    • 0242361266 scopus 로고    scopus 로고
    • Effects of fat-soluble extracts from vegetable powder and β-carotene on proliferation and apoptosis of lung cancer cell YTMLC-90
    • Lu Q.J., Huang C.Y., Yao S.X., Ru A., Wang S., Wut X.N. Effects of fat-soluble extracts from vegetable powder and β-carotene on proliferation and apoptosis of lung cancer cell YTMLC-90. Biomedical and Environmental Sciences 2003, 6:237-245.
    • (2003) Biomedical and Environmental Sciences , vol.6 , pp. 237-245
    • Lu, Q.J.1    Huang, C.Y.2    Yao, S.X.3    Ru, A.4    Wang, S.5    Wut, X.N.6
  • 92
    • 79952148035 scopus 로고    scopus 로고
    • Antioxidant activities of β-carotene compounds in different in vitro assays
    • Mueller L., Boehm V. Antioxidant activities of β-carotene compounds in different in vitro assays. Molecules 2011, 16:1055-1069.
    • (2011) Molecules , vol.16 , pp. 1055-1069
    • Mueller, L.1    Boehm, V.2
  • 95
    • 79956080227 scopus 로고    scopus 로고
    • Astaxanthin inhibits tumour invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2
    • Nagendraprabhu P., Sudhandiran G. Astaxanthin inhibits tumour invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. Investigational New Drugs 2011, 29:207-224.
    • (2011) Investigational New Drugs , vol.29 , pp. 207-224
    • Nagendraprabhu, P.1    Sudhandiran, G.2
  • 96
    • 0034011558 scopus 로고    scopus 로고
    • Antioxidant activities of astaxanthin and related carotenoids
    • Naguib Y.M. Antioxidant activities of astaxanthin and related carotenoids. Journal of Agricultural and Food Chemistry 2000, 48:1150-1154.
    • (2000) Journal of Agricultural and Food Chemistry , vol.48 , pp. 1150-1154
    • Naguib, Y.M.1
  • 97
    • 0035821778 scopus 로고    scopus 로고
    • Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27 Kip1 in the cyclin E-cdk2 complexes
    • Nahum A., Hirsch K., Danilenko M., Watts C.K., Prall O.W., Levy J., Sharoni Y. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27 Kip1 in the cyclin E-cdk2 complexes. Oncogene 2001, 20:3428-3436.
    • (2001) Oncogene , vol.20 , pp. 3428-3436
    • Nahum, A.1    Hirsch, K.2    Danilenko, M.3    Watts, C.K.4    Prall, O.W.5    Levy, J.6    Sharoni, Y.7
  • 99
    • 2442434515 scopus 로고    scopus 로고
    • Intake of specific carotenoids and essential fatty acids and breast cancer risk in Montreal, Canada
    • Nkondjock A., Ghadirian P. Intake of specific carotenoids and essential fatty acids and breast cancer risk in Montreal, Canada. The American Journal of Clinical Nutrition 2004, 79:857-864.
    • (2004) The American Journal of Clinical Nutrition , vol.79 , pp. 857-864
    • Nkondjock, A.1    Ghadirian, P.2
  • 100
    • 84894576431 scopus 로고    scopus 로고
    • Inverse associations between serum concentrations of zeaxanthin and other carotenoids and colorectal neoplasm in Japanese
    • Okuyama Y., Ozasa K., Oki K., Nishino H., Fujimoto S., Watanabe Y. Inverse associations between serum concentrations of zeaxanthin and other carotenoids and colorectal neoplasm in Japanese. International Journal of Clinical Oncology 2013, 19:87-97.
    • (2013) International Journal of Clinical Oncology , vol.19 , pp. 87-97
    • Okuyama, Y.1    Ozasa, K.2    Oki, K.3    Nishino, H.4    Fujimoto, S.5    Watanabe, Y.6
  • 101
    • 0025602410 scopus 로고
    • Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumour cells
    • Okuzumi J., Nishino H., Murakoshi M., Iwashima A., Tanaka Y., Yamane T., Fujita Y., Takahashi T. Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumour cells. Cancer Letters 1990, 55:75-81.
    • (1990) Cancer Letters , vol.55 , pp. 75-81
    • Okuzumi, J.1    Nishino, H.2    Murakoshi, M.3    Iwashima, A.4    Tanaka, Y.5    Yamane, T.6    Fujita, Y.7    Takahashi, T.8
  • 102
    • 0000269318 scopus 로고
    • Absorption, transport and metabolism of carotenoids in humans
    • Olson J.A. Absorption, transport and metabolism of carotenoids in humans. Pure and Applied Chemistry 1994, 66:1011-1016.
    • (1994) Pure and Applied Chemistry , vol.66 , pp. 1011-1016
    • Olson, J.A.1
  • 105
    • 0036199442 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by β-carotene through down-regulation of cyclin A and Bcl-2 family proteins
    • Palozza P., Serini S., Maggiano N., Angelini M., Boninsegna A., Di Nicuolo F., Ranelletti F.O., Calviello G. Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by β-carotene through down-regulation of cyclin A and Bcl-2 family proteins. Carcinogenesis 2002, 23:11-18.
    • (2002) Carcinogenesis , vol.23 , pp. 11-18
    • Palozza, P.1    Serini, S.2    Maggiano, N.3    Angelini, M.4    Boninsegna, A.5    Di Nicuolo, F.6    Ranelletti, F.O.7    Calviello, G.8
  • 107
    • 79959724646 scopus 로고    scopus 로고
    • Tomato lycopene and lung cancer prevention: From experimental to human studies
    • Palozza P., Simone R.E., Catalano A., Mele M.C. Tomato lycopene and lung cancer prevention: From experimental to human studies. Cancers 2011, 3:2333-2357.
    • (2011) Cancers , vol.3 , pp. 2333-2357
    • Palozza, P.1    Simone, R.E.2    Catalano, A.3    Mele, M.C.4
  • 108
    • 67650450196 scopus 로고    scopus 로고
    • Growth-inhibitory effects of the astaxanthin-rich alga, Haematococcus pluvialis in human colon cancer cells
    • Palozza P., Torelli C., Boninsegna A., Simone R., Catalano A., Mele M.C., Picci N. Growth-inhibitory effects of the astaxanthin-rich alga, Haematococcus pluvialis in human colon cancer cells. Cancer Letters 2009, 283:108-117.
    • (2009) Cancer Letters , vol.283 , pp. 108-117
    • Palozza, P.1    Torelli, C.2    Boninsegna, A.3    Simone, R.4    Catalano, A.5    Mele, M.C.6    Picci, N.7
  • 109
    • 30644470449 scopus 로고    scopus 로고
    • The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells
    • Park Y.O., Hwang E.S., Moon T.W. The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells. Biofactors (Oxford, England) 2005, 23:129-139.
    • (2005) Biofactors (Oxford, England) , vol.23 , pp. 129-139
    • Park, Y.O.1    Hwang, E.S.2    Moon, T.W.3
  • 110
    • 0029966118 scopus 로고    scopus 로고
    • Absorption, metabolism, and transport of carotenoids
    • Parker R.S. Absorption, metabolism, and transport of carotenoids. The FASEB Journal 1996, 10:542-551.
    • (1996) The FASEB Journal , vol.10 , pp. 542-551
    • Parker, R.S.1
  • 112
    • 77954977193 scopus 로고    scopus 로고
    • Combined antioxidant carotenoids and the risk of persistent human papillomavirus infection
    • Peterson C.E., Sedjo R.L., Davis F.G., Beam C.A., Giuliano A.R. Combined antioxidant carotenoids and the risk of persistent human papillomavirus infection. Nutrition and Cancer 2010, 62:728-733.
    • (2010) Nutrition and Cancer , vol.62 , pp. 728-733
    • Peterson, C.E.1    Sedjo, R.L.2    Davis, F.G.3    Beam, C.A.4    Giuliano, A.R.5
  • 116
    • 0242579264 scopus 로고    scopus 로고
    • Lycopene: Its role in human health and disease
    • Rao L.G., Guns E., Rao A.V. Lycopene: Its role in human health and disease. Agro Food 2003, 7:25-30.
    • (2003) Agro Food , vol.7 , pp. 25-30
    • Rao, L.G.1    Guns, E.2    Rao, A.V.3
  • 118
    • 84889768148 scopus 로고    scopus 로고
    • Cancer preventive efficacy of marine carotenoid fucoxanthin: Cell cycle arrest and apoptosis
    • Rengarajan T., Rajendran P., Nandakumar N., Balasubramanian M.P., Nishigaki I. Cancer preventive efficacy of marine carotenoid fucoxanthin: Cell cycle arrest and apoptosis. Nutrients 2013, 5:4978-4989.
    • (2013) Nutrients , vol.5 , pp. 4978-4989
    • Rengarajan, T.1    Rajendran, P.2    Nandakumar, N.3    Balasubramanian, M.P.4    Nishigaki, I.5
  • 119
    • 0036224148 scopus 로고    scopus 로고
    • A cohort study of dietary carotenoids and lung cancer risk in women (Canada)
    • Rohan T.E., Jain M., Howe G.R., Miller A.B. A cohort study of dietary carotenoids and lung cancer risk in women (Canada). Cancer Causes and Control 2002, 13:231-237.
    • (2002) Cancer Causes and Control , vol.13 , pp. 231-237
    • Rohan, T.E.1    Jain, M.2    Howe, G.R.3    Miller, A.B.4
  • 121
    • 84856451575 scopus 로고    scopus 로고
    • Effects of lycopene and apigenin on human umbilical vein endothelial cells in vitro under angiogenic stimulation
    • Sahin M., Sahin E., Gumuslu S. Effects of lycopene and apigenin on human umbilical vein endothelial cells in vitro under angiogenic stimulation. Acta Histochemica 2012, 114:94-100.
    • (2012) Acta Histochemica , vol.114 , pp. 94-100
    • Sahin, M.1    Sahin, E.2    Gumuslu, S.3
  • 123
    • 63149159259 scopus 로고    scopus 로고
    • Long-term use of β-carotene, retinol, lycopene, and lutein supplements and lung cancer risk: Results from the vitamins and lifestyle (VITAL) study
    • Satia J.A., Littman A., Slatore C.G., Galanko J.A., White E. Long-term use of β-carotene, retinol, lycopene, and lutein supplements and lung cancer risk: Results from the vitamins and lifestyle (VITAL) study. American Journal of Epidemiology 2009, 169:815-828.
    • (2009) American Journal of Epidemiology , vol.169 , pp. 815-828
    • Satia, J.A.1    Littman, A.2    Slatore, C.G.3    Galanko, J.A.4    White, E.5
  • 124
    • 84858782415 scopus 로고    scopus 로고
    • Fucoxanthin induces GADD45α expression and G1 arrest with SAPK/JNK activation in LNCaP human prostate cancer cells
    • Satomi Y. Fucoxanthin induces GADD45α expression and G1 arrest with SAPK/JNK activation in LNCaP human prostate cancer cells. Anticancer Research 2012, 32:807-813.
    • (2012) Anticancer Research , vol.32 , pp. 807-813
    • Satomi, Y.1
  • 125
    • 61749096564 scopus 로고    scopus 로고
    • Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and GADD45 expression by the carotenoid fucoxanthin in human cancer cells
    • Satomi Y., Nishino H. Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and GADD45 expression by the carotenoid fucoxanthin in human cancer cells. Biochimica et Biophysica Acta (BBA)-General Subjects 2009, 1790:260-266.
    • (2009) Biochimica et Biophysica Acta (BBA)-General Subjects , vol.1790 , pp. 260-266
    • Satomi, Y.1    Nishino, H.2
  • 127
    • 0036338757 scopus 로고    scopus 로고
    • A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands)
    • Schuurman A.G., Goldbohm R.A., Brants H.A., van den Brandt P.A. A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands). Cancer Causes and Control 2002, 13:573-582.
    • (2002) Cancer Causes and Control , vol.13 , pp. 573-582
    • Schuurman, A.G.1    Goldbohm, R.A.2    Brants, H.A.3    van den Brandt, P.A.4
  • 130
  • 132
    • 1842424987 scopus 로고    scopus 로고
    • Efficacy of oral lycopene in the treatment of oral leukoplakia
    • Singh M., Krishanappa R., Bagewadi A., Keluskar V. Efficacy of oral lycopene in the treatment of oral leukoplakia. Oral Oncology 2004, 40:591-596.
    • (2004) Oral Oncology , vol.40 , pp. 591-596
    • Singh, M.1    Krishanappa, R.2    Bagewadi, A.3    Keluskar, V.4
  • 135
    • 0036637235 scopus 로고    scopus 로고
    • Chemoprevention: An essential approach to controlling cancer
    • Sporn M.B., Suh N. Chemoprevention: An essential approach to controlling cancer. Nature Reviews. Cancer 2002, 2:537-543.
    • (2002) Nature Reviews. Cancer , vol.2 , pp. 537-543
    • Sporn, M.B.1    Suh, N.2
  • 137
    • 84903531452 scopus 로고    scopus 로고
    • Siphonaxanthin, a green algal carotenoid, as a novel functional compound
    • Sugawara T., Ganesan P., Li Z., Manabe Y., Hirata T. Siphonaxanthin, a green algal carotenoid, as a novel functional compound. Marine Drugs 2014, 12:3660-3668.
    • (2014) Marine Drugs , vol.12 , pp. 3660-3668
    • Sugawara, T.1    Ganesan, P.2    Li, Z.3    Manabe, Y.4    Hirata, T.5
  • 140
    • 84873733806 scopus 로고    scopus 로고
    • Intakes of fruits, vegetables, and related vitamins and lung cancer risk: Results from the Shanghai Men's Health Study (2002-2009)
    • Takata Y., Xiang Y.B., Yang G., Li H., Gao J., Cai H., Gao Y.T., Zheng W., Shu X.O. Intakes of fruits, vegetables, and related vitamins and lung cancer risk: Results from the Shanghai Men's Health Study (2002-2009). Nutrition and Cancer 2013, 65:51-61.
    • (2013) Nutrition and Cancer , vol.65 , pp. 51-61
    • Takata, Y.1    Xiang, Y.B.2    Yang, G.3    Li, H.4    Gao, J.5    Cai, H.6    Gao, Y.T.7    Zheng, W.8    Shu, X.O.9
  • 141
    • 84895558622 scopus 로고    scopus 로고
    • Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines
    • Takeshima M., Ono M., Higuchi T., Chen C., Hara T., Nakano S. Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines. Cancer Science 2014, 105:252-257.
    • (2014) Cancer Science , vol.105 , pp. 252-257
    • Takeshima, M.1    Ono, M.2    Higuchi, T.3    Chen, C.4    Hara, T.5    Nakano, S.6
  • 142
    • 84858965591 scopus 로고    scopus 로고
    • Cancer chemoprevention by carotenoids
    • Tanaka T., Shnimizu M., Moriwaki H. Cancer chemoprevention by carotenoids. Molecules 2012, 17:3202-3242.
    • (2012) Molecules , vol.17 , pp. 3202-3242
    • Tanaka, T.1    Shnimizu, M.2    Moriwaki, H.3
  • 143
    • 49649112171 scopus 로고    scopus 로고
    • Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway
    • Tang F.Y., Shih C.J., Cheng L.H., Ho H.J., Chen H.J. Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Molecular Nutrition and Food Research 2008, 52:646-654.
    • (2008) Molecular Nutrition and Food Research , vol.52 , pp. 646-654
    • Tang, F.Y.1    Shih, C.J.2    Cheng, L.H.3    Ho, H.J.4    Chen, H.J.5
  • 145
    • 78650737833 scopus 로고    scopus 로고
    • Singlet molecular oxygen-quenching activity of carotenoids: Relevance to protection of the skin from photoaging
    • Terao J., Minami Y., Bando N. Singlet molecular oxygen-quenching activity of carotenoids: Relevance to protection of the skin from photoaging. Journal of Clinical Biochemistry and Nutrition 2011, 48:57.
    • (2011) Journal of Clinical Biochemistry and Nutrition , vol.48 , pp. 57
    • Terao, J.1    Minami, Y.2    Bando, N.3
  • 146
    • 34250026235 scopus 로고    scopus 로고
    • A highly polar xanthophyll of 9'-cis-neoxanthin induces apoptosis in HCT-116 human colon cancer cells through mitochondrial dysfunction
    • Terasaki M., Asai A., Zhang H., Nagao A. A highly polar xanthophyll of 9'-cis-neoxanthin induces apoptosis in HCT-116 human colon cancer cells through mitochondrial dysfunction. Molecular and Cellular Biochemistry 2007, 300:227-237.
    • (2007) Molecular and Cellular Biochemistry , vol.300 , pp. 227-237
    • Terasaki, M.1    Asai, A.2    Zhang, H.3    Nagao, A.4
  • 147
    • 84860710284 scopus 로고    scopus 로고
    • Crocetin, a carotenoid derivative, inhibits VEGF-induced angiogenesis via suppression of p38 phosphorylation
    • Umigai N., Tanaka J., Tsuruma K., Shimazawa M., Hara H. Crocetin, a carotenoid derivative, inhibits VEGF-induced angiogenesis via suppression of p38 phosphorylation. Current Neurovascular Research 2012, 9:102-109.
    • (2012) Current Neurovascular Research , vol.9 , pp. 102-109
    • Umigai, N.1    Tanaka, J.2    Tsuruma, K.3    Shimazawa, M.4    Hara, H.5
  • 148
    • 36949030846 scopus 로고    scopus 로고
    • Cell cycle regulation and induction of apoptosis by β-carotene in U937 and HL-60 leukemia cells
    • Upadhyaya K., Radha K., Madhyastha H. Cell cycle regulation and induction of apoptosis by β-carotene in U937 and HL-60 leukemia cells. Journal of Biochemistry and Molecular Biology 2007, 40:1009.
    • (2007) Journal of Biochemistry and Molecular Biology , vol.40 , pp. 1009
    • Upadhyaya, K.1    Radha, K.2    Madhyastha, H.3
  • 149
    • 84876288018 scopus 로고    scopus 로고
    • Selective inhibition of cell proliferation by lycopene in MCF-7 breast cancer cells in vitro: A proteomic analysis
    • Uppala P.T., Dissmore T., Lau B.H., Andacht T., Rajaram S. Selective inhibition of cell proliferation by lycopene in MCF-7 breast cancer cells in vitro: A proteomic analysis. Phytotherapy Research 2013, 27:595-601.
    • (2013) Phytotherapy Research , vol.27 , pp. 595-601
    • Uppala, P.T.1    Dissmore, T.2    Lau, B.H.3    Andacht, T.4    Rajaram, S.5
  • 153
    • 0023688120 scopus 로고
    • Inhibition of adriamycin-promoted microsomal lipid peroxidation by β-carotene, α-tocopherol and retinol at high and low oxygen partial pressures
    • Vile G.F., Winterbourn C.C. Inhibition of adriamycin-promoted microsomal lipid peroxidation by β-carotene, α-tocopherol and retinol at high and low oxygen partial pressures. FEBS Letters 1988, 238:353-356.
    • (1988) FEBS Letters , vol.238 , pp. 353-356
    • Vile, G.F.1    Winterbourn, C.C.2
  • 155
    • 84867273775 scopus 로고    scopus 로고
    • In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice
    • Wang J., Chen S., Xu S., Yu X., Ma D., Hu X., Cao X. In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice. Marine Drugs 2012, 10:2055-2068.
    • (2012) Marine Drugs , vol.10 , pp. 2055-2068
    • Wang, J.1    Chen, S.2    Xu, S.3    Yu, X.4    Ma, D.5    Hu, X.6    Cao, X.7
  • 156
    • 10044248489 scopus 로고    scopus 로고
    • The world oral health report 2003: Continuous improvement of oral health in the 21st century
    • WHO (2003). The world oral health report 2003: Continuous improvement of oral health in the 21st century - The approach of the WHO global oral health programme.
    • (2003) The approach of the WHO global oral health programme.
  • 159
    • 84918492860 scopus 로고    scopus 로고
    • Anti-proliferative effects of lycopene and β-cryptoxanthin on human lung adenocarcinoma A549 cells
    • Wu T.T., Wang K.C., Jow G.M. Anti-proliferative effects of lycopene and β-cryptoxanthin on human lung adenocarcinoma A549 cells. Fu-Jen Journal of Medicine 2010, 8:67-74.
    • (2010) Fu-Jen Journal of Medicine , vol.8 , pp. 67-74
    • Wu, T.T.1    Wang, K.C.2    Jow, G.M.3
  • 160
    • 84862267642 scopus 로고    scopus 로고
    • Anti-metastatic effects and mechanisms of apo-8'-lycopenal, an enzymatic metabolite of lycopene, against human hepatocarcinoma SK-Hep-1 cells
    • Yang C.M., Hu T.Y., Hu M.L. Anti-metastatic effects and mechanisms of apo-8'-lycopenal, an enzymatic metabolite of lycopene, against human hepatocarcinoma SK-Hep-1 cells. Nutrition and Cancer 2012, 64:274-285.
    • (2012) Nutrition and Cancer , vol.64 , pp. 274-285
    • Yang, C.M.1    Hu, T.Y.2    Hu, M.L.3
  • 162
    • 79959945798 scopus 로고    scopus 로고
    • Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines
    • Yasui Y., Hosokawa M., Mikami N., Miyashita K., Tanaka T. Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines. Chemico-Biological Interactions 2011, 193:79-87.
    • (2011) Chemico-Biological Interactions , vol.193 , pp. 79-87
    • Yasui, Y.1    Hosokawa, M.2    Mikami, N.3    Miyashita, K.4    Tanaka, T.5
  • 164
    • 34047207526 scopus 로고    scopus 로고
    • Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells
    • Yoshiko S., Hoyoku N. Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells. In Vivo (Athens, Greece) 2007, 21:305-309.
    • (2007) In Vivo (Athens, Greece) , vol.21 , pp. 305-309
    • Yoshiko, S.1    Hoyoku, N.2
  • 165
    • 79952487250 scopus 로고    scopus 로고
    • Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway
    • Yu R.X., Hu X.M., Xu S.Q., Jiang Z.J., Yang W. Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway. European Journal of Pharmacology 2011, 657:10-19.
    • (2011) European Journal of Pharmacology , vol.657 , pp. 10-19
    • Yu, R.X.1    Hu, X.M.2    Xu, S.Q.3    Jiang, Z.J.4    Yang, W.5
  • 167
    • 0034922077 scopus 로고    scopus 로고
    • Prediagnostic levels of serum β-cryptoxanthin and retinol predict smoking-related lung cancer risk in Shanghai, China
    • Yuan J., Ross R., Chu X., Gao Y., Yu M. Prediagnostic levels of serum β-cryptoxanthin and retinol predict smoking-related lung cancer risk in Shanghai, China. Cancer Epidemiology, Biomarkers & Prevention 2001, 10:767.
    • (2001) Cancer Epidemiology, Biomarkers & Prevention , vol.10 , pp. 767
    • Yuan, J.1    Ross, R.2    Chu, X.3    Gao, Y.4    Yu, M.5
  • 168
    • 84896841068 scopus 로고    scopus 로고
    • Microalgal carotenoids: Beneficial effects and potential in human health
    • Zhang J., Sun Z., Sun P., Chen T., Chen F. Microalgal carotenoids: Beneficial effects and potential in human health. Food and Function 2014, 5:413-425.
    • (2014) Food and Function , vol.5 , pp. 413-425
    • Zhang, J.1    Sun, Z.2    Sun, P.3    Chen, T.4    Chen, F.5
  • 171
    • 79959854178 scopus 로고    scopus 로고
    • Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells
    • Zhang X., Zhao W.E., Hu L., Zhao L., Huang J. Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells. Archives of Biochemistry and Biophysics 2011, 512:96-106.
    • (2011) Archives of Biochemistry and Biophysics , vol.512 , pp. 96-106
    • Zhang, X.1    Zhao, W.E.2    Hu, L.3    Zhao, L.4    Huang, J.5
  • 172
    • 58149350379 scopus 로고    scopus 로고
    • Potential chemoprevention effect of dietary fucoxanthin on urinary bladder cancer EJ-1 cell line
    • Zhang Z., Zhang P., Hamada M., Takahashi S., Xing G., Liu J., Sugiura N. Potential chemoprevention effect of dietary fucoxanthin on urinary bladder cancer EJ-1 cell line. Oncology Reports 2008, 20:1099-1103.
    • (2008) Oncology Reports , vol.20 , pp. 1099-1103
    • Zhang, Z.1    Zhang, P.2    Hamada, M.3    Takahashi, S.4    Xing, G.5    Liu, J.6    Sugiura, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.