Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways

Journal of Experimental Medicine

Volumn 208, Issue 12, 2011, Pages 2429-2447

  Swarup, Vivek ^a   Phaneuf, Daniel ^a   Dupré, Nicolas ^b   Petri, Susanne ^c   Strong, Michael ^d   Kriz, Jasna ^a   Julien, Jean Pierre ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; MESSENGER RNA; MUTANT PROTEIN; REACTIVE OXYGEN METABOLITE; TAR DNA BINDING PROTEIN; TRANSCRIPTION FACTOR RELA; WITHAFERIN A;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; HUMAN; HUMAN TISSUE; MOUSE; MUSCLE DENERVATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA ANALYSIS; TRANSGENE;

AMYOTROPHIC LATERAL SCLEROSIS; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; DNA PRIMERS; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; NEUROGLIA; NEUROMUSCULAR JUNCTION; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPINAL CORD; TRANSCRIPTION FACTOR RELA; TRANSGENES; WITHANOLIDES;

EID: 84855515796     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20111313     Document Type: Article

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