Inhibition of monosodium urate crystal-induced inflammation by withaferin A

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 11, Issue 4, 2008, Pages 46-55

  Sabina, Evan Prince ^a   Chandel, Sonal ^a   Rasool, Mahaboob Khan ^b  

^a VIT UNIVERSITY   (India)

^b MANAGEMENT AND SCIENCE UNIVERSITY   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTIOXIDANT; DRUG DERIVATIVE; ERGOSTEROL; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; URIC ACID; WITHAFERIN A;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; FEMALE; INFLAMMATION; LIPID PEROXIDATION; LYSOSOME; MALE; METABOLISM; MOUSE; NEUTROPHIL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; ERGOSTEROL; FEMALE; INDOMETHACIN; INFLAMMATION; INTERFERON-ALPHA; LIPID PEROXIDATION; LYSOSOMES; MALE; MICE; NEUTROPHILS; URIC ACID;

EID: 65249139441     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: 10.18433/j35k58     Document Type: Article

References (33)

1. Schweyer S, Hemmerlein B, Radzun HJ, Fayyazi A. Continuous recruitment, co-expression of tumour nerosis factor-alpha and matrix metallo proteinases, and apoptosis of macrophages in gout tophi. Virchows Arch, 2000; 437: 534-539.
2. Di Giovine FS, Malawista SE, Nuki G, Duff GW. Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1, J Immunol, 1987; 138: 3213-3218.
3. Terkeltaub R. Pathogenesis and treatment of crystal-induced inflammation. In: Koopman WJ, Moreland LW (eds), Arthritis and Allied conditions, Philadelphia, Lippincott, Williams and Wilkins, pp, 2357-2372, 2004.
4. Grandhi A, Mujumdar AM, Patwardhan B. A comparative pharmacological investigations of Ashwagandha and Ginseng. J. Ethanopharmacol, 1994;44: 131-135.
5. Ali M, Shuaib M. Withanolides from the stem bark of Withania somnifera. Phytochemistry, 1997; 44(6): 1163-1168.
6. Fugner A. Inhibition of immunologically induced inflammation by the plant steroid withaferin A. Arzneimittelforschung 1973; 23(7): 932-935.
7. Mohan R, Hammers HJ, Bargagna-Mohan P, Zhan XH. Herbstritt CJ, Ruiz A. Withaferin A is a potent inhibitor of angiogenesis. Angiogenesis, 2004; 7:115-22.
8. Singh D, Aggarwal A, Maurya R, Naik S. Withania somnifera inhibits NF-kappa B and AP-1 transcription factors in human peripheral blood and synovial fluid mononuclear cells. Phytother Res, 2007; 21(10): 905-913.
9. Ichikawa H, Takada Y, Shishodia S, Jayaprakasam B, Nair MG, Aggarwal BB. Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NFkappaB) activation and NF-kappaB-regulated gene expression. Mol Cancer Ther, 2006; 5(6):1434-45.
10. Kaileh M, Berghe WV, Heyerick A, Horion J, Piette J, Liber C, Keukeleir DD, Essawi T, and Haegeman G. Withaferin A Strongly Elicits Ikk beta Hyperphosphorylation Concomitant with Potent Inhibition of Its Kinase Activity. J. Biol. Chem, 2007;7: 4253-4264.
11. Begum VH, Sadique J. Long term effect of herbal drug Withania somnifera on adjuvant-induced arthritis in rats. Indian J Exp Biol, 1988; 26 (11): 877-882.
12. Anbalagan K, Sadique J. Influence of Indian medicine (Ashwagandha) on acute phase reactants in inflammation Indian J Exp Biol, 1981; 19(3): 245-9.
13. Rasool M, Varalakshmi P. Suppressive effect of Withania somnifera root powder on MSU crystalinduced Inflammation-an in vivo and in vitro study. Chem-Biol Interact, 2006; 164(3): 174-80.
14. Rasool M, Varalakshmi P. Protective effect of Withania somnifera root powder in relation to lipid peroxidation, antioxidant status, glycoproteins and bone collagen on adjuvantinduced arthritis in rats. Fundam Clin Pharmacol, 2007; 21(2):157-64.
15. King J. The hydrolases-acid and alkaline phosphatases, In: Van D (ed), Practical clinical enzymology, Nostrand Company Limited, London, pp, 191-208, 1965b.
16. Kawai Y, Anno K. Mucopolysaccharidedegrading enzymes from the liver of the Squad, Ommastrephesslonaipacificus.I.Hyaluronidase. Biochim. Biophys. Acta, 1971; 242: 428-436.
17. Rosenblit PD, Metzyer RP, Wick AN. Effect of Streptozotocin diabetes on acid phosphatase and selected glycosidase activities of serum and various rat organs. Proc. Soc. Exp. Biol Med, 1974; 145: 244-247.
18. Marhun D. Rapid colorimetric assay of β-galactosidase and N-acetyl-β-galactosaminidase in human urine. Clin.Chim.Acta, 1976;73: 453-461.
19. Lowry OH, Rosebrough NJ, Farr AI, Randall RJ. Protein measurement with the folin phenol reagent. J.Biol.Chem, 1951; 193: 265-275.
20. Ledwozyw A, Michalak J, Stepien A, Kadziolka A. The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis. Clin.Chim.Acta, 1986;155: 275-284.
21. Hogberg J, Larson RE, Kristoferson A, Orrenius S. NADPH-dependent reductase solubilised from microsomes of peroxidation and its activity. Biochem. Biophys. Res. Commun, 1974; 56: 836-842.
22. Marklund SL, Marklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem, 1974; 47: 469-474.
23. Sinha AK. Colorimetric assay of Catalase. Anal. Biochem, 1972; 47: 389-394.
24. Rotruk JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hekstra WG. Selenium, biochemical role as a component of glutathione peroxidase purification and assay. Science, 1973;179: 588-590.
25. King J. The dehydrogenase or oxidoreductaselactate dehydrogenase. In: Van D (ed), Practical Clinical Enzymology, Nostrand, London, pp, 83-93, 1965.
26. Landis RC, Haskard DO. Pathogenesis of crystalinduced inflammation. Curr Rheumatol Rep, 2001; 3:36-41.
27. Tate GA, Mandell BF, Schumacher HR Jr, Zurier RB. Suppression of acute inflammation by 15 methyl prostaglandin E1. Lab Invest, 1988; 59:192-199.
28. Gallin JI. The neutrophil. In: Samber M, Talmage DW, Frank MM, Austen KF, Claman HN, ed. Immunological diseases, Little Brown Co., Boston, MA, pp, 737-788, 1988.
29. Gupta OP, Sharma N, Chand DA. Sensitive and selective model for evaluating anti-inflammatory activity-papaya latex-induced rat paw inflammation. J Pharmacol Toxicol Methods, 1992; 28 (1): 15-19.
30. Rasool M, Sabina EP, Lavanya B. Antiinflammatory effect of Spirulina fusiformis on adjuvant-induced arthritis in mice, Biol. Pharm Bull, 2006; 29(1):2483-7.
31. Ramprasad VR, Shanthi P, Sachdanandam P. Evaluation of antioxidant effect of Semecarpus anacardium Linn.nut extract on thecomponents of immune system in adjuvant arthritis. Vasc. Pharmacol, 2005; 42: 179-186.
32. Wallingford WR, McCarty DT. Differential membronolytic effects of sodium urate and calcium pyro phosphate dihydrate crystals, J. Exp. Med, 1971; 133: 100.
33. Lawrence T, Willoughby DA, Gilroy DW. Antiinflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol, 2002; 2:787-795.