Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19158-19170

  Saxena, Anita ^a   Banasavadi Siddegowda, Yeshavanth K ^a,c   Fan, Yifei ^a   Bhattacharya, Sumit ^a   Roy, Gargi ^a   Giovannucci, David R ^a   Frizzell, Raymond A ^b   Wang, Xiaodong ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY EPITHELIAL CELLS; CELL SURFACES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; ENDOPLASMIC RETICULUM; FUNCTIONAL EXPRESSION; GOLGI COMPARTMENTS; HEAT SHOCK PROTEIN; ISOFORMS; MISFOLDED PROTEINS; MOLECULAR CHAPERONES; MULTIPLE LEVELS; NUCLEOTIDE-EXCHANGE FACTOR; PROTEIN MISFOLDING; STEADY-STATE LEVEL; SUBSTRATE BINDING DOMAIN;

BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANES; DEGRADATION; MACHINERY; NUCLEOTIDES; QUALITY ASSURANCE; QUALITY CONTROL;

PROTEINS;

CELL PROTEIN; CHAPERONE; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 105; HEAT SHOCK PROTEIN 105ALPHA; HEAT SHOCK PROTEIN 110; NUCLEOTIDE EXCHANGE FACTOR; PHENYLALANINE; PROTEIN BAG 2; PROTEIN HSPBP1; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; GENE DELETION; GENETIC TRANSFECTION; GOLGI COMPLEX; HOMEOSTASIS; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MISFOLDING; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS REGULATION; PROTEIN TRANSPORT; QUALITY CONTROL; RESPIRATORY EPITHELIUM; STEADY STATE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; HSC70 HEAT-SHOCK PROTEINS; HSP110 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN TRANSPORT; PROTEOLYSIS; RESPIRATORY MUCOSA;

EID: 84861749562     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.297580     Document Type: Article

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