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Volumn 145, Issue 2, 2013, Pages 431-441

Withania somnifera root extract ameliorates hypobaric hypoxia induced memory impairment in rats

Author keywords

Corticosterone; Hippocampus; Hypobaric hypoxia; Memory impairment; Neurodegeneration; Nitric oxide; Withania somnifera

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CORTICOSTERONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; WITHANIA SOMNIFERA EXTRACT;

EID: 84872152942     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.063     Document Type: Article
Times cited : (80)

References (50)
  • 1
    • 0035027583 scopus 로고    scopus 로고
    • Acute mountain sickness, prophylactic benefits of antioxidant vitamin supplementation at high altitude
    • D.M. Baily, and B. Davies Acute mountain sickness, prophylactic benefits of antioxidant vitamin supplementation at high altitude High Altitude Biology and Medicine 2 2001 21 29
    • (2001) High Altitude Biology and Medicine , vol.2 , pp. 21-29
    • Baily, D.M.1    Davies, B.2
  • 4
    • 64549090002 scopus 로고    scopus 로고
    • Isradipine antagonizes hypobaric hypoxia induced CA1 damage and memory impairment: Complementary roles of l-type calcium channel and NMDA receptors
    • K. Barhwal, S.K. Hota, I. Baitharu, D. Prasad, S.B. Singh, and G. Ilavazhagan Isradipine antagonizes hypobaric hypoxia induced CA1 damage and memory impairment: complementary roles of l-type calcium channel and NMDA receptors Neurobiology of Disease 34 2009 230 244
    • (2009) Neurobiology of Disease , vol.34 , pp. 230-244
    • Barhwal, K.1    Hota, S.K.2    Baitharu, I.3    Prasad, D.4    Singh, S.B.5    Ilavazhagan, G.6
  • 6
    • 70349591047 scopus 로고    scopus 로고
    • Neuroprotective effects of Withania somnifera dunal.: A possible mechanism
    • M. Bhatnagar, D. Sharma, and M. Salvi Neuroprotective effects of Withania somnifera dunal.: a possible mechanism Neurochemical Research 34 2009 1975 1983
    • (2009) Neurochemical Research , vol.34 , pp. 1975-1983
    • Bhatnagar, M.1    Sharma, D.2    Salvi, M.3
  • 7
    • 0028942248 scopus 로고
    • Effects of glycowithanolides from Withania somnifera on an animal model of Alzheimer's disease and perturbed central cholinergic markers of cognition in rats
    • S.K. Bhattacharya, A. Kumar, and S. Ghosal Effects of glycowithanolides from Withania somnifera on an animal model of Alzheimer's disease and perturbed central cholinergic markers of cognition in rats Phytotherapy Research 9 1995 110 113
    • (1995) Phytotherapy Research , vol.9 , pp. 110-113
    • Bhattacharya, S.K.1    Kumar, A.2    Ghosal, S.3
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 33749598284 scopus 로고    scopus 로고
    • The involvement of nitric oxide and prostaglandins in the cholinergic stimulation of hypothalamic-pituitary-Adrenal response during crowding stress
    • A.J. Bugajski, A. Gadek-Michalska, and J. Bugajski The involvement of nitric oxide and prostaglandins in the cholinergic stimulation of hypothalamic-pituitary-Adrenal response during crowding stress Journal of Physiology and Pharmacology 57 2006 463 477
    • (2006) Journal of Physiology and Pharmacology , vol.57 , pp. 463-477
    • Bugajski, A.J.1    Gadek-Michalska, A.2    Bugajski, J.3
  • 11
    • 0033840501 scopus 로고    scopus 로고
    • Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse
    • S.S. Chaurasia, S. Panda, and A. Kar Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse Pharmacology Research 41 2000 663 666
    • (2000) Pharmacology Research , vol.41 , pp. 663-666
    • Chaurasia, S.S.1    Panda, S.2    Kar, A.3
  • 12
    • 41149136192 scopus 로고    scopus 로고
    • Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection
    • N.D. Chaurasiya, G.C. Uniyal, P. Lal, L. Misra, N.S. Sangwan, R. Tuli, and R.S. Sangwan Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection Phytochemical Analysis 19 2008 148 154
    • (2008) Phytochemical Analysis , vol.19 , pp. 148-154
    • Chaurasiya, N.D.1    Uniyal, G.C.2    Lal, P.3    Misra, L.4    Sangwan, N.S.5    Tuli, R.6    Sangwan, R.S.7
  • 13
    • 0030986255 scopus 로고    scopus 로고
    • In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA and p-chloroamphetamine but not the degeneration following fenfluramine
    • M.I. Colado, E. OShea, R. Granaburn litvakdos, T.K. Murray, and A.R. Green In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA and p-chloroamphetamine but not the degeneration following fenfluramine British Journal of Pharmacology 121 1997 889 900
    • (1997) British Journal of Pharmacology , vol.121 , pp. 889-900
    • Colado, M.I.1    Oshea, E.2    Granaburn Litvakdos, R.3    Murray, T.K.4    Green, A.R.5
  • 14
    • 0031858672 scopus 로고    scopus 로고
    • Effect of nitric oxide on rat adrenal zona fasciculata steroidogenesis
    • C.B. Cymeryng, L.A. Dada, and E.J. Podesta Effect of nitric oxide on rat adrenal zona fasciculata steroidogenesis Journal of Endocrinology 158 1998 197 203
    • (1998) Journal of Endocrinology , vol.158 , pp. 197-203
    • Cymeryng, C.B.1    Dada, L.A.2    Podesta, E.J.3
  • 15
    • 0023183219 scopus 로고
    • Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria
    • N.P. Das, and A.K. Ratty Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria Biochemical Medicine and Metabolic Biology 37 1987 258 264
    • (1987) Biochemical Medicine and Metabolic Biology , vol.37 , pp. 258-264
    • Das, N.P.1    Ratty, A.K.2
  • 16
    • 0031891552 scopus 로고    scopus 로고
    • Effect of ashwagandha on lipid peroxidation in stress-induced animals
    • J.N. Dhuley Effect of ashwagandha on lipid peroxidation in stress-induced animals Journal of Ethnopharmacology 60 1998 173 178
    • (1998) Journal of Ethnopharmacology , vol.60 , pp. 173-178
    • Dhuley, J.N.1
  • 18
    • 46849097808 scopus 로고    scopus 로고
    • Nitric oxide in the adrenergic-And CRH-induced activation of hypothalamic-pituitary-Adrenal axis
    • A. Gadek-Michalska, and J. Bugajski Nitric oxide in the adrenergic-And CRH-induced activation of hypothalamic-pituitary-Adrenal axis Journal Physiology and Pharmacology 59 2008 365 378
    • (2008) Journal Physiology and Pharmacology , vol.59 , pp. 365-378
    • Gadek-Michalska, A.1    Bugajski, J.2
  • 19
    • 0017064979 scopus 로고
    • A fluorimetric method for determination of oxidized and reduced glutathione in tissue
    • P.J. Hissin, and R. Hilf A fluorimetric method for determination of oxidized and reduced glutathione in tissue Analytical Biochemistry 74 1976 214 226
    • (1976) Analytical Biochemistry , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 21
    • 41649115986 scopus 로고    scopus 로고
    • Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia
    • S.K. Hota, K. Barhwal, K. Ray, S.B. Singh, and G. Ilavazhagan Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia Neurobiology of Learning and Memory 89 2008 522 532
    • (2008) Neurobiology of Learning and Memory , vol.89 , pp. 522-532
    • Hota, S.K.1    Barhwal, K.2    Ray, K.3    Singh, S.B.4    Ilavazhagan, G.5
  • 22
    • 81755171406 scopus 로고    scopus 로고
    • Protective role of Ashwagandha leaf extract and its component withanone on scopolamine-induced changes in the brain and brain-derived cells
    • A. Konar, N. Shah, R. Singh, N. Saxena, S.C. Kaul, R. Wadhwa, and M.K. Thakur Protective role of Ashwagandha leaf extract and its component withanone on scopolamine-induced changes in the brain and brain-derived cells PLoS ONE 6 2011 1 13
    • (2011) PLoS ONE , vol.6 , pp. 1-13
    • Konar, A.1    Shah, N.2    Singh, R.3    Saxena, N.4    Kaul, S.C.5    Wadhwa, R.6    Thakur, M.K.7
  • 24
    • 17844363245 scopus 로고    scopus 로고
    • Neuritic regeneration and synaptic reconstruction induced by withanolide A
    • T. Kuboyama, C. Tohda, and K. Komatsu Neuritic regeneration and synaptic reconstruction induced by withanolide A British Journal of Pharmacology 144 2005 961 971
    • (2005) British Journal of Pharmacology , vol.144 , pp. 961-971
    • Kuboyama, T.1    Tohda, C.2    Komatsu, K.3
  • 25
    • 0025313038 scopus 로고
    • Organometal-induced increases in oxygen reactive species: The potential of 2,7-dichlorofluorescin diacetate as an index of neurotoxic damage
    • C.P. LeBel, S.F. Ali, M. McKee, and S.C. Bondy Organometal-induced increases in oxygen reactive species: the potential of 2,7-dichlorofluorescin diacetate as an index of neurotoxic damage Toxicology and Applied Pharmacology 104 1990 17 24
    • (1990) Toxicology and Applied Pharmacology , vol.104 , pp. 17-24
    • Lebel, C.P.1    Ali, S.F.2    McKee, M.3    Bondy, S.C.4
  • 26
    • 0034256345 scopus 로고    scopus 로고
    • Effects of acute exposure to mild or moderate hypoxia on human psychomotor performance and visual-reaction time
    • X.Y. Li, X.Y. Wu, C. Fu, X.F. Shen, C.B. Yang, and Y.H. Wu Effects of acute exposure to mild or moderate hypoxia on human psychomotor performance and visual-reaction time Space Medicine and Medical Engineering 13 2000 235 239
    • (2000) Space Medicine and Medical Engineering , vol.13 , pp. 235-239
    • Li, X.Y.1    Wu, X.Y.2    Fu, C.3    Shen, X.F.4    Yang, C.B.5    Wu, Y.H.6
  • 27
    • 63249131616 scopus 로고    scopus 로고
    • Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation
    • C.W. Lipari, J.E. Garcia, Y. Zhao, K. Thrift, D. Vaidya, and A. Rodriguez Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation Fertility and Sterility 9 2009 1316 1318
    • (2009) Fertility and Sterility , vol.9 , pp. 1316-1318
    • Lipari, C.W.1    Garcia, J.E.2    Zhao, Y.3    Thrift, K.4    Vaidya, D.5    Rodriguez, A.6
  • 28
    • 34848817652 scopus 로고    scopus 로고
    • Hypobaric hypoxia damages the hippocampal pyramidal neurons in the rat brain
    • P. Maiti, S.B. Singh, S. Muthuraju, S. Veleri, and G. Ilavazhagan Hypobaric hypoxia damages the hippocampal pyramidal neurons in the rat brain Brain Research 1175 2007 1 9
    • (2007) Brain Research , vol.1175 , pp. 1-9
    • Maiti, P.1    Singh, S.B.2    Muthuraju, S.3    Veleri, S.4    Ilavazhagan, G.5
  • 29
    • 33646776390 scopus 로고    scopus 로고
    • 2-OHE2-induced oocyte maturation involves steroidogenesis in cat fish
    • A. Mishra, and K.P. Roy 2-OHE2-induced oocyte maturation involves steroidogenesis in cat fish Journal of Endocrinology 189 2006 341 353
    • (2006) Journal of Endocrinology , vol.189 , pp. 341-353
    • Mishra, A.1    Roy, K.P.2
  • 31
    • 0021173996 scopus 로고
    • Development of a water maze procedure for studying spatial learning the rat
    • R.G.M. Morris Development of a water maze procedure for studying spatial learning the rat Journal of Neuroscience Methods 11 1984 47 60
    • (1984) Journal of Neuroscience Methods , vol.11 , pp. 47-60
    • Morris, R.G.M.1
  • 33
    • 0037718255 scopus 로고    scopus 로고
    • Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
    • O. Myhre, J.M. Andersen, H. Aarnes, and F. Fonnum Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation Biochemistry and Pharmacology 65 2003 1575 1582
    • (2003) Biochemistry and Pharmacology , vol.65 , pp. 1575-1582
    • Myhre, O.1    Andersen, J.M.2    Aarnes, H.3    Fonnum, F.4
  • 34
    • 33144467788 scopus 로고    scopus 로고
    • Effect of Withania somnifera root extract on reserpine-induced orofacial dyskinesia and cognitive dysfunction
    • P.S. Naidu, A. Singh, and S.K. Kulkarni Effect of Withania somnifera root extract on reserpine-induced orofacial dyskinesia and cognitive dysfunction Phytotherapy Research 20 2006 140 146
    • (2006) Phytotherapy Research , vol.20 , pp. 140-146
    • Naidu, P.S.1    Singh, A.2    Kulkarni, S.K.3
  • 36
    • 2342512006 scopus 로고    scopus 로고
    • Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: Prevention by extracts of Withania somnifera and Aloe vera
    • M.S. Parihar, M. Chaudhary, R. Shetty, and T. Hemnani Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: prevention by extracts of Withania somnifera and Aloe vera Journal of Clinical Neurosciences 11 2004 397 402
    • (2004) Journal of Clinical Neurosciences , vol.11 , pp. 397-402
    • Parihar, M.S.1    Chaudhary, M.2    Shetty, R.3    Hemnani, T.4
  • 37
    • 18744388841 scopus 로고    scopus 로고
    • A reversal by l-Arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus
    • V. Paul, L. Reddy, and P. Ekambaram A reversal by l-Arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus Indian Journal of Physiology and Pharmacology 49 2005 179 186
    • (2005) Indian Journal of Physiology and Pharmacology , vol.49 , pp. 179-186
    • Paul, V.1    Reddy, L.2    Ekambaram, P.3
  • 38
    • 57549096513 scopus 로고    scopus 로고
    • Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex
    • L.O. Pereira, P.M. Nabinger, A.C. Strapasson, P. Nardin, C.A. Gonçalves, I.R. Siqueira, and C.A. Netto Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex Brain Research 1247 2009 188 195
    • (2009) Brain Research , vol.1247 , pp. 188-195
    • Pereira, L.O.1    Nabinger, P.M.2    Strapasson, A.C.3    Nardin, P.4    Gonçalves, C.A.5    Siqueira, I.R.6    Netto, C.A.7
  • 40
    • 0027332693 scopus 로고
    • Permanent increase of the GAD67/synaptophysin ratio in rat cerebral cortex nerve endings as a result of hypoxic ischemic encephalopathy sustained in early postnatal life: A confocal laser scanning microscopic study
    • H.J. Romijn, J. van Marle, and A.W. Janszen Permanent increase of the GAD67/synaptophysin ratio in rat cerebral cortex nerve endings as a result of hypoxic ischemic encephalopathy sustained in early postnatal life: a confocal laser scanning microscopic study Brain Research 630 1993 315 329
    • (1993) Brain Research , vol.630 , pp. 315-329
    • Romijn, H.J.1    Van Marle, J.2    Janszen, A.W.3
  • 41
    • 80051920133 scopus 로고    scopus 로고
    • Correlation between cognitive functions and nitric oxide levels in patients with dementia
    • R. Sachdeva, R. Babbar, V. Puri, S. Agarwal, and B. Krishana Correlation between cognitive functions and nitric oxide levels in patients with dementia Clinical EEG Neurosciences 42 2011 190 194
    • (2011) Clinical EEG Neurosciences , vol.42 , pp. 190-194
    • Sachdeva, R.1    Babbar, R.2    Puri, V.3    Agarwal, S.4    Krishana, B.5
  • 42
    • 0031032337 scopus 로고    scopus 로고
    • Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain
    • R. Schliebs, A. Liebmann, S.K. Bhattacharya, A. Kumar, S. Ghosal, and V. Bigl Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain Neurochemistry International 30 1997 181 190
    • (1997) Neurochemistry International , vol.30 , pp. 181-190
    • Schliebs, R.1    Liebmann, A.2    Bhattacharya, S.K.3    Kumar, A.4    Ghosal, S.5    Bigl, V.6
  • 43
    • 0038526374 scopus 로고    scopus 로고
    • Adaptogenic activity of a novel withanolide-free aqueous fraction from the roots of Withania somnifera Dun. (Part II)
    • B. Singh, B.K. Chandan, and D.K. Gupta Adaptogenic activity of a novel withanolide-free aqueous fraction from the roots of Withania somnifera Dun. (Part II) Phytotherapy Research 17 2003 531 536
    • (2003) Phytotherapy Research , vol.17 , pp. 531-536
    • Singh, B.1    Chandan, B.K.2    Gupta, D.K.3
  • 45
    • 84866687472 scopus 로고    scopus 로고
    • Oxidative stress induced NMDA receptor alteration leads to spatial memory deficits in temporal lobe epilepsy: Ameliorative effects of Withania somnifera and withanolide A
    • S. Soman, P.K. Korah, S. Jayanarayanan, J. Mathew, and C.S. Paulose Oxidative stress induced NMDA receptor alteration leads to spatial memory deficits in temporal lobe epilepsy: ameliorative effects of Withania somnifera and withanolide A Neurochemistry Research 37 2012 1915 1927
    • (2012) Neurochemistry Research , vol.37 , pp. 1915-1927
    • Soman, S.1    Korah, P.K.2    Jayanarayanan, S.3    Mathew, J.4    Paulose, C.S.5
  • 46
    • 84886641325 scopus 로고
    • A simple and sensitive method of acetylcholine identification and assay. Bioassay combined with minicolumn gel filtration or high-performance liquid chromatography
    • E.S. Vizi, L.G. Hársing Jr.; D. Duncalf, H. Nagashima, P. Potter, and F.F. Foldes A simple and sensitive method of acetylcholine identification and assay. Bioassay combined with minicolumn gel filtration or high-performance liquid chromatography Journal of Pharmacological Methods 13 1985 201 211
    • (1985) Journal of Pharmacological Methods , vol.13 , pp. 201-211
    • Vizi, E.S.1    Hársing, Jr.L.G.2    Duncalf, D.3    Nagashima, H.4    Potter, P.5    Foldes, F.F.6
  • 47
    • 0027936877 scopus 로고
    • Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brain
    • C.M. Weber, B.C. Eke, and M.D. Maines Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brain Journal of Neurochemistry 63 1994 953 962
    • (1994) Journal of Neurochemistry , vol.63 , pp. 953-962
    • Weber, C.M.1    Eke, B.C.2    Maines, M.D.3


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