Heme oxygenase-1-derived bilirubin protects endothelial cells against high glucose-induced damage

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 91-98

  He, Meihua ^a,d   Nitti, Mariapaola ^b   Piras, Sabrina ^b   Furfaro, Anna Lisa ^c   Traverso, Nicola ^b   Pronzato, Maria Adelaide ^b   Mann, Giovanni E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF GENOA   (Italy)

^c G GASLINI INSTITUTE   (Italy)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Bilirubin; Endothelial cells; eNOS; Heme oxygenase 1; Hyperglycemia; Nrf2; Oxidativestress

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BILIRUBIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; HEME OXYGENASE 1; N(G) NITROARGININE METHYL ESTER; REACTIVE OXYGEN METABOLITE; ROTENONE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; TIRON; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; MESSENGER RNA; SWEETENING AGENT;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; AORTA ENDOTHELIUM; AORTIC ENDOTHELIAL CELL; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIUM CELL; GLUCOSE INTAKE; INTRACELLULAR SIGNALING; MOLECULAR PATHOLOGY; MONOTHERAPY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; UPREGULATION; ANIMAL; AORTA; APOPTOSIS; BOVINE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; GEL MOBILITY SHIFT ASSAY; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; AORTA; APOPTOSIS; BILIRUBIN; BLOTTING, WESTERN; CATTLE; CELL PROLIFERATION; CELLS, CULTURED; CYTOPROTECTION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIUM, VASCULAR; GLUCOSE; HEME OXYGENASE-1; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SWEETENING AGENTS;

EID: 84942415689     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.07.151     Document Type: Article

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