Gestational diabetes mellitus impairs nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero

Diabetes

Volumn 62, Issue 12, 2013, Pages 4088-4097

  Cheng, Xinghua ^a   Chapple, Sarah J ^a   Patel, Bijal ^a   Puszyk, William ^a   Sugden, David ^b   Yin, Xiaoke ^a   Mayr, Manuel ^a   Siow, Richard C M ^a   Mann, Giovanni E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; CYSTINE; CYSTINE TRANSPORTER; GLUTAMATE CYSTEINE LIGASE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE SYNTHASE; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; SMALL INTERFERING RNA; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CPG ISLAND; DNA DAMAGE; DNA METHYLATION; ENDOTHELIUM CELL; FEMALE; FETUS; FETUS CELL; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIPID PEROXIDATION; NEWBORN; OXIDATION; OXIDATION REDUCTION STATE; PREGNANCY DIABETES MELLITUS; PRENATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ADULT; ANTIOXIDANTS; DIABETES, GESTATIONAL; FEMALE; GLUTATHIONE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PREGNANCY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84891820074     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0169     Document Type: Article

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