Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1

Free Radical Biology and Medicine

Volumn 52, Issue 2, 2012, Pages 488-496

  Furfaro, Anna Lisa ^a   MacAy, José Raúl Zumba ^a   Marengo, Barbara ^b   Nitti, Mariapaola ^a   Parodi, Alessia ^c   Fenoglio, Daniela ^c   Marinari, Umberto Maria ^a   Pronzato, Maria Adelaide ^a   Domenicotti, Cinzia ^a   Traverso, Nicola ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Cancer; Etoposide; Free radicals; Glutathione; Heme oxygenase 1; Neuroblastoma; Nrf2; Oxidative stress

Indexed keywords

BUTHIONINE SULFOXIMINE; ETOPOSIDE; GLUTATHIONE; HEME OXYGENASE 1; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME INDUCTION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR RESISTANCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BUTHIONINE SULFOXIMINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE-1; HUMANS; NEUROBLASTOMA; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTOPORPHYRINS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 84855427508     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.007     Document Type: Article

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