Validating CFD Predictions of Pharmaceutical Aerosol Deposition with in Vivo Data

Pharmaceutical Research

Volumn 32, Issue 10, 2015, Pages 3170-3187

  Tian, Geng ^a   Hindle, Michael ^b   Lee, Sau ^c   Longest, P Worth ^a,b  

^a Virginia Commonwealth University   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

airway dosimetry predictions; computational fluid dynamics (CFD); pharmaceutical aerosols; predictions of aerosol deposition; respiratory drug delivery

Indexed keywords

BUDESONIDE; FENOTEROL; AEROSOL;

AEROSOL; ARTICLE; COMPUTATIONAL FLUID DYNAMICS; DRUG DELIVERY SYSTEM; DRY POWDER; FLOW RATE; GAMMA SCINTIGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; IN VIVO STUDY; LAMINAR FLOW; METERED DOSE INHALER; PARTICLE SIZE; PEAK INSPIRATORY FLOW; PREDICTION; PRIORITY JOURNAL; SOFT MIST INHALER; STEADY STATE; TIDAL VOLUME; TURBULENT FLOW; ANATOMIC MODEL; COMPUTER SIMULATION; DRUG EFFECTS; DRY POWDER INHALER; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM; PHARMACOLOGY; PHYSIOLOGY; PROCEDURES; THEORETICAL MODEL; TISSUE DISTRIBUTION;

ADMINISTRATION, INHALATION; AEROSOLS; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; DRY POWDER INHALERS; HUMANS; LUNG; MODELS, ANATOMIC; MODELS, THEORETICAL; PARTICLE SIZE; TISSUE DISTRIBUTION;

EID: 84942369471     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-015-1695-1     Document Type: Article

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