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Volumn 44, Issue 2, 2012, Pages 146-156

Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease

Author keywords

Asthma; chronic obstructive pulmonary disease; drug particle size; physiology; Small airways; therapy

Indexed keywords

ANTIINFLAMMATORY AGENT; BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CICLESONIDE; CORTICOSTEROID; FLUNISOLIDE; FORMOTEROL; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MUSCARINIC RECEPTOR BLOCKING AGENT; TIOTROPIUM BROMIDE;

EID: 84857722564     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2011.585656     Document Type: Article
Times cited : (80)

References (111)
  • 3
    • 0014062847 scopus 로고
    • Resistance of central and peripheral airways measured by a retrograde catheter
    • Macklem PT, Mead J. Resistance of central and peripheral airways measured by a retrograde catheter. J Appl Physiol. 1967;22:395-401.
    • (1967) J Appl Physiol. , vol.22 , pp. 395-401
    • MacKlem, P.T.1    Mead, J.2
  • 4
    • 0014932298 scopus 로고
    • The lung' s'q uiet zone'
    • Mead J. The lung' s 'q uiet zone' . N Engl J Med. 1970; 282:1318-9.
    • (1970) N Engl J Med. , vol.282 , pp. 1318-1319
    • Mead, J.1
  • 5
    • 33748098907 scopus 로고    scopus 로고
    • Against the Dutch hypo thesis: Asthma and chronic obstructive pulmonary disease are distinct diseases
    • Barnes PJ. Against the Dutch hypothesis: asthma and chronic obstructive pulmonary disease are distinct diseases. Am J Respir Crit Care Med. 2006;174:240-3.
    • (2006) Am J Respir Crit Care Med. , vol.174 , pp. 240-243
    • Barnes, P.J.1
  • 7
    • 2942720573 scopus 로고    scopus 로고
    • The nature of small-airway obstruction in chronic obstructive pulmonary disease
    • Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med. 2004;350:2645-53.
    • (2004) N Engl J Med. , vol.350 , pp. 2645-2653
    • Hogg, J.C.1    Chu, F.2    Utokaparch, S.3    Woods, R.4    Elliott, W.M.5    Buzatu, L.6
  • 8
    • 73549101104 scopus 로고    scopus 로고
    • The small airways and distal lung compartment in asthma and COPD: A time for reappraisal
    • Contoli M, Bousquet J, Fabbri LM, Magnussen H, Rabe KF, Siafakas NM, et al. The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy. 2010;65:141-51.
    • (2010) Allergy. , vol.65 , pp. 141-151
    • Contoli, M.1    Bousquet, J.2    Fabbri, L.M.3    Magnussen, H.4    Rabe, K.F.5    Siafakas, N.M.6
  • 9
    • 75349084388 scopus 로고    scopus 로고
    • The importance and features of the distal airways in children and adults
    • Gelfand EW, Kraft M. The importance and features of the distal airways in children and adults. J Allergy Clin Immunol. 2009;124:S84-7.
    • (2009) J Allergy Clin Immunol. , vol.124
    • Gelfand, E.W.1    Kraft, M.2
  • 10
    • 0026026853 scopus 로고
    • Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma
    • Saetta M, Di Stefano A, Rosina C, Thiene G, Fabbri LM. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am Rev Respir Dis. 1991;143:138-43.
    • (1991) Am Rev Respir Dis. , vol.143 , pp. 138-143
    • Saetta, M.1    Di Stefano, A.2    Rosina, C.3    Thiene, G.4    Fabbri, L.M.5
  • 14
    • 0022356652 scopus 로고
    • Loss of alveolar attachments in smokers. A morphometric correlate of lung function impairment
    • Saetta M, Ghezzo H, Kim WD, King M, Angus GE, Wang NS, et al. Loss of alveolar attachments in smokers. A morphometric correlate of lung function impairment. Am Rev Respir Dis. 1985;132:894-900.
    • (1985) Am Rev Respir Dis. , vol.132 , pp. 894-900
    • Saetta, M.1    Ghezzo, H.2    Kim, W.D.3    King, M.4    Angus, G.E.5    Wang, N.S.6
  • 15
    • 0034061777 scopus 로고    scopus 로고
    • Subepithelial immunopathology of the large airways in smokers with and without chronic obstructive pulmonary disease
    • Lams BE, Sousa AR, Rees PJ, Lee TH. Subepithelial immunopathology of the large airways in smokers with and without chronic obstructive pulmonary disease. Eur Respir J. 2000;15:512-6.
    • (2000) Eur Respir J. , vol.15 , pp. 512-516
    • Lams, B.E.1    Sousa, A.R.2    Rees, P.J.3    Lee, T.H.4
  • 18
    • 0031054821 scopus 로고    scopus 로고
    • The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics
    • Carroll N, Cooke C, James A. The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. Eur Respir J. 1997;10:292-300.
    • (1997) Eur Respir J. , vol.10 , pp. 292-300
    • Carroll, N.1    Cooke, C.2    James, A.3
  • 20
    • 0037092562 scopus 로고    scopus 로고
    • Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease
    • Saetta M, Mariani M, Panina-Bordignon P, Turato G, Buonsanti C, Baraldo S, et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2002;165:1404-9.
    • (2002) Am J Respir Crit Care Med. , vol.165 , pp. 1404-1409
    • Saetta, M.1    Mariani, M.2    Panina-Bordignon, P.3    Turato, G.4    Buonsanti, C.5    Baraldo, S.6
  • 21
    • 31844446296 scopus 로고    scopus 로고
    • Multimodality measurements of small airways disease
    • King GG, Salome CM. Multimodality measurements of small airways disease. Eur Respir J. 2006;27:250-2.
    • (2006) Eur Respir J. , vol.27 , pp. 250-252
    • King, G.G.1    Salome, C.M.2
  • 23
    • 0035989738 scopus 로고    scopus 로고
    • Transbronchial biopsy as a tool to evaluate small airways in asthma
    • Balzar S, Wenzel SE, Chu HW. Transbronchial biopsy as a tool to evaluate small airways in asthma. Eur Respir J. 2002;20:254-9.
    • (2002) Eur Respir J. , vol.20 , pp. 254-259
    • Balzar, S.1    Wenzel, S.E.2    Chu, H.W.3
  • 24
    • 0034076579 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha production in human alveolar macrophages: Modulation by inhaled corticosteroid
    • Marshall BG, Wangoo A, Harrison LI, Young DB, Shaw RJ. Tumour necrosis factor-alpha production in human alveolar macrophages: modulation by inhaled corticosteroid. Eur Respir J. 2000;15:764-70.
    • (2000) Eur Respir J. , vol.15 , pp. 764-770
    • Marshall, B.G.1    Wangoo, A.2    Harrison, L.I.3    Young, D.B.4    Shaw, R.J.5
  • 25
    • 0033044857 scopus 로고    scopus 로고
    • Induced sputum for the investigation of airway infl ammation: Evidence for its clinical application
    • Hargreave FE. Induced sputum for the investigation of airway infl ammation: evidence for its clinical application. Can Respir J. 1999;6:169-74.
    • (1999) Can Respir J. , vol.6 , pp. 169-174
    • Hargreave, F.E.1
  • 29
    • 0037841783 scopus 로고    scopus 로고
    • Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: Assessment of response to methacholine and exercise challenge
    • Samee S, Altes T, Powers P, de Lange EE, Knight-Scott J, Rakes G, et al. Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. J Allergy Clin Immunol. 2003;111:1205-11.
    • (2003) J Allergy Clin Immunol. , vol.111 , pp. 1205-1211
    • Samee, S.1    Altes, T.2    Powers, P.3    De Lange, E.E.4    Knight-Scott, J.5    Rakes, G.6
  • 30
    • 33750043741 scopus 로고    scopus 로고
    • Evaluation of asthma with hyperpolarized helium-3 MRI: Correlation with clinical severity and spirometry
    • de Lange EE, Altes TA, Patrie JT, Gaare JD, Knake JJ, Mugler JP 3rd, et al. Evaluation of asthma with hyperpolarized helium-3 MRI: correlation with clinical severity and spirometry. Chest. 2006;130:1055-62.
    • (2006) Chest. , vol.130 , pp. 1055-1062
    • De Lange, E.E.1    Altes, T.A.2    Patrie, J.T.3    Gaare, J.D.4    Knake, J.J.5    Mugler III, J.P.6
  • 32
    • 44449111614 scopus 로고    scopus 로고
    • Quantitatively assessed dynamic contrast-enhanced magnetic resonance imaging in patients with chronic obstructive pulmonary disease: Correlation of perfusion parameters with pulmonary function test and quantitative computed tomography
    • Jang YM, Oh YM, Seo JB, Kim N, Chae EJ, Lee YK, et al. Quantitatively assessed dynamic contrast-enhanced magnetic resonance imaging in patients with chronic obstructive pulmonary disease: correlation of perfusion parameters with pulmonary function test and quantitative computed tomography. Invest Radiol. 2008;43:403-10.
    • (2008) Invest Radiol. , vol.43 , pp. 403-410
    • Jang, Y.M.1    Oh, Y.M.2    Seo, J.B.3    Kim, N.4    Chae, E.J.5    Lee, Y.K.6
  • 33
    • 31144467357 scopus 로고    scopus 로고
    • Positron emission tomography imaging of regional pulmonary perfusion and ventilation
    • Musch G, Venegas JG. Positron emission tomography imaging of regional pulmonary perfusion and ventilation. Proc Am Thorac Soc. 2005;2:522-7.
    • (2005) Proc Am Thorac Soc. , vol.2 , pp. 522-527
    • Musch, G.1    Venegas, J.G.2
  • 35
    • 69549103465 scopus 로고    scopus 로고
    • Imaging the lungs in patients with pulmonary emphysema
    • Goldin JG. Imaging the lungs in patients with pulmonary emphysema. J Thorac Imaging. 2009;24:163-70.
    • (2009) J Thorac Imaging. , vol.24 , pp. 163-170
    • Goldin, J.G.1
  • 36
    • 0031949780 scopus 로고    scopus 로고
    • Airway wall thickness in patients with near fatal asthma and control groups: Assessment with high resolution computed tomographic scanning
    • Awadh N, Mü ller NL, Park CS, Abboud RT, FitzGerald JM. Airway wall thickness in patients with near fatal asthma and control groups: assessment with high resolution computed tomographic scanning. Thorax. 1998;53:248-53.
    • (1998) Thorax. , vol.53 , pp. 248-253
    • Awadh, N.1    Müller, N.L.2    Park, C.S.3    Abboud, R.T.4    Fitzgerald, J.M.5
  • 37
    • 0007862628 scopus 로고    scopus 로고
    • Airway obstruction in asthmatic and healthy individuals: Inspiratory and expiratory thin-section CT fi ndings
    • Park CS, Mü ller NL, Worthy SA, Kim JS, Awadh N, Fitzgerald M. Airway obstruction in asthmatic and healthy individuals: inspiratory and expiratory thin-section CT fi ndings. Radiology. 1997;203:361-7.
    • (1997) Radiology. , vol.203 , pp. 361-367
    • Park, C.S.1    Müller, N.L.2    Worthy, S.A.3    Kim, J.S.4    Awadh, N.5    Fitzgerald, M.6
  • 39
    • 58149234897 scopus 로고    scopus 로고
    • Quantitative CT in chronic obstructive pulmonary disease: Inspiratory and expiratory assessment
    • Akira M, Toyokawa K, Inoue Y, Arai T. Quantitative CT in chronic obstructive pulmonary disease: inspiratory and expiratory assessment. Am J Roentgenol. 2009;192:267-72.
    • (2009) Am J Roentgenol. , vol.192 , pp. 267-272
    • Akira, M.1    Toyokawa, K.2    Inoue, Y.3    Arai, T.4
  • 41
    • 39749163309 scopus 로고    scopus 로고
    • Quantitative assessment of air trapping in chronic obstructive pulmonary disease using inspiratory and expiratory volumetric MDCT
    • Matsuoka S, Kurihara Y, Yagihashi K, Hoshino M, Watanabe N, Nakajima Y. Quantitative assessment of air trapping in chronic obstructive pulmonary disease using inspiratory and expiratory volumetric MDCT. AJR Am J Roentgenol. 2008;190:762-9.
    • (2008) AJR Am J Roentgenol. , vol.190 , pp. 762-769
    • Matsuoka, S.1    Kurihara, Y.2    Yagihashi, K.3    Hoshino, M.4    Watanabe, N.5    Nakajima, Y.6
  • 42
    • 0033407462 scopus 로고    scopus 로고
    • Comparative effects of hydrofl uoroalkane and chlorofl uorocarbon beclomethasone dipropionate inhalation on small airways: Assessment with functional helical thin-section computed tomography
    • Goldin JG, Tashkin DP, Kleerup EC, Greaser LE, Haywood UM, Sayre JW, et al. Comparative effects of hydrofl uoroalkane and chlorofl uorocarbon beclomethasone dipropionate inhalation on small airways: assessment with functional helical thin-section computed tomography. J Allergy Clin Immunol. 1999;104:S258-67.
    • (1999) J Allergy Clin Immunol. , vol.104
    • Goldin, J.G.1    Tashkin, D.P.2    Kleerup, E.C.3    Greaser, L.E.4    Haywood, U.M.5    Sayre, J.W.6
  • 44
    • 31144450284 scopus 로고    scopus 로고
    • Hyperpolarized 3-helium magnetic resonance imaging to probe lung function
    • van Beek EJ, Wild JM. Hyperpolarized 3-helium magnetic resonance imaging to probe lung function. Proc Am Thorac Soc. 2005;2:528-32.
    • (2005) Proc Am Thorac Soc. , vol.2 , pp. 528-532
    • Van Beek, E.J.1    Wild, J.M.2
  • 48
    • 46849100822 scopus 로고    scopus 로고
    • Assessment of the lung microstructure in patients with asthma using hyperpolarized 3He diffusion MRI at two time scales: Comparison with healthy subjects and patients with COPD
    • Wang C, Altes TA, Mugler JP 3rd, Miller GW, Ruppert K, Mata JF, et al. Assessment of the lung microstructure in patients with asthma using hyperpolarized 3He diffusion MRI at two time scales: comparison with healthy subjects and patients with COPD. J Magn Reson Imaging. 2008; 28:80-8.
    • (2008) J Magn Reson Imaging. , vol.28 , pp. 80-8
    • Wang, C.1    Altes, T.A.2    Mugler Iii, J.P.3    Miller, G.W.4    Ruppert, K.5    Mata, J.F.6
  • 49
    • 0035755516 scopus 로고    scopus 로고
    • Tests of forced expiration and inspiration
    • Pride NB. Tests of forced expiration and inspiration. Clin Chest Med. 2001;22:599-622.
    • (2001) Clin Chest Med. , vol.22 , pp. 599-622
    • Pride, N.B.1
  • 50
    • 70349878828 scopus 로고    scopus 로고
    • The role of small airways in monitoring the response to asthma treatment: What is beyond FEV1?
    • Scichilone N, Battaglia S, Olivieri D, Bellia V. The role of small airways in monitoring the response to asthma treatment: what is beyond FEV1? Allergy. 2009;64:1563-9.
    • (2009) Allergy. , vol.64 , pp. 1563-1569
    • Scichilone, N.1    Battaglia, S.2    Olivieri, D.3    Bellia, V.4
  • 51
    • 0026038935 scopus 로고
    • Lung function testing: Selection of reference values and interpretive strategies
    • American Thoracic Society
    • Lung function testing: selection of reference values and interpretive strategies. American Thoracic Society. Am Rev Respir Dis. 1991;144:1202-18.
    • (1991) Am Rev Respir Dis. , vol.144 , pp. 1202-1218
  • 52
    • 33344460134 scopus 로고    scopus 로고
    • Discriminating measures and normal values for expiratory obstruction
    • Hansen JE, Sun XG, Wasserman K. Discriminating measures and normal values for expiratory obstruction. Chest. 2006;129:369-77.
    • (2006) Chest. , vol.129 , pp. 369-377
    • Hansen, J.E.1    Sun, X.G.2    Wasserman, K.3
  • 53
    • 0028931061 scopus 로고
    • Reference values for residual volume, functional residual capacity and total lung capacity
    • Stocks J, Quanjer PH. Reference values for residual volume, functional residual capacity and total lung capacity. Eur Respir J. 1995;8:492-506.
    • (1995) Eur Respir J. , vol.8 , pp. 492-506
    • Stocks, J.1    Quanjer, P.H.2
  • 54
    • 33845620271 scopus 로고    scopus 로고
    • The clinical importance of dynamic lung hyperinfl ation in COPD
    • O' D onnell DE, Laveneziana P. The clinical importance of dynamic lung hyperinfl ation in COPD. COPD. 2006;3: 219-32.
    • (2006) COPD , vol.3 , pp. 219-232
    • Donnell D E, O.'.1    Laveneziana, P.2
  • 55
    • 33750076332 scopus 로고    scopus 로고
    • Dynamic hyperinfl ation during bronchoconstriction in asthma: Implications for symptom perception
    • Lougheed MD, Fisher T,O'Donnell DE. Dynamic hyperinfl ation during bronchoconstriction in asthma: implications for symptom perception. Chest. 2006;130:1072-81.
    • (2006) Chest. , vol.130 , pp. 1072-1081
    • Lougheed, M.D.1    Fisher, T.2    O'Donnell, D.E.3
  • 56
    • 77952954174 scopus 로고    scopus 로고
    • Abnormalities of plethysmographic lung volumes in asthmatic children
    • Mahut B, Bokov P, Delclaux C. Abnormalities of plethysmographic lung volumes in asthmatic children. Respir Med. 2010;104:966-71.
    • (2010) Respir Med. , vol.104 , pp. 966-971
    • Mahut, B.1    Bokov, P.2    Delclaux, C.3
  • 57
    • 38949165471 scopus 로고    scopus 로고
    • Lung function in adults with stable but severe asthma: Air trapping and incomplete reversal of obstruction with bronchodilation
    • National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, et al. National Heart, Lung, and Blood Institute Severe Asthma Research Program. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol. 2008;104:394-403.
    • (2008) J Appl Physiol. , vol.104 , pp. 394-403
    • Sorkness, R.L.1    Bleecker, E.R.2    Busse, W.W.3    Calhoun, W.J.4    Castro, M.5    Chung, K.F.6
  • 59
    • 0034131479 scopus 로고    scopus 로고
    • Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes
    • Veen JC, Beekman AJ, Bel EH, Sterk PJ. Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. Am J Respir Crit Care Med. 2000;161:1902-6.
    • (2000) Am J Respir Crit Care Med. , vol.161 , pp. 1902-1906
    • Veen, J.C.1    Beekman, A.J.2    Bel, E.H.3    Sterk, P.J.4
  • 61
    • 61649088166 scopus 로고    scopus 로고
    • Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage i COPD
    • O'Donnell DE, Laveneziana P, Ora J, Webb KA, Lam YM, Ofir D. Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD. Thorax. 2009;64:216-23.
    • (2009) Thorax. , vol.64 , pp. 216-223
    • O'Donnell, D.E.1    Laveneziana, P.2    Ora, J.3    Webb, K.A.4    Lam, Y.M.5    Ofir, D.6
  • 62
    • 0014528998 scopus 로고
    • Frequency dependence of compliance as a test for obstruction in the small airways
    • Woolcock AJ, Vincent NJ, Macklem PT. Frequency dependence of compliance as a test for obstruction in the small airways. J Clin Invest. 1969;48:1097-106.
    • (1969) J Clin Invest. , vol.48 , pp. 1097-106
    • Woolcock, A.J.1    Vincent, N.J.2    MacKlem, P.T.3
  • 63
    • 0031849309 scopus 로고    scopus 로고
    • Small airways: A time to revisit?
    • Evans DJ, Green M. Small airways: a time to revisit? Thorax. 1998;53:629-30.
    • (1998) Thorax. , vol.53 , pp. 629-630
    • Evans, D.J.1    Green, M.2
  • 64
    • 0021139802 scopus 로고
    • Current status of small airways disease
    • Buist AS. Current status of small airways disease. Chest. 1984;86:100-5.
    • (1984) Chest. , vol.86 , pp. 100-105
    • Buist, A.S.1
  • 66
    • 17644363081 scopus 로고    scopus 로고
    • ATS/ERS recommendations for standardized procedures for the online and offl ine measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide
    • American Thoracic Society; European Respiratory Society
    • American Thoracic Society; European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offl ine measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide. Am J Respir Crit Care Med. 2005;171:912-30.
    • (2005) Am J Respir Crit Care Med. , vol.171 , pp. 912-930
  • 67
    • 0031928989 scopus 로고    scopus 로고
    • A two-compartment model of pulmonary nitric oxide exchange dynamics
    • Tsoukias NM, George SC. A two-compartment model of pulmonary nitric oxide exchange dynamics. J Appl Physiol. 1998;85:653-66.
    • (1998) J Appl Physiol. , vol.85 , pp. 653-666
    • Tsoukias, N.M.1    George, S.C.2
  • 69
    • 77955294728 scopus 로고    scopus 로고
    • Central and peripheral airway/alveolar sites of exhaled nitric oxide in acute asthma
    • Gelb AF, George SC, Silkoff PE, Krishnan A, Fraser C, Taylor CF, et al. Central and peripheral airway/alveolar sites of exhaled nitric oxide in acute asthma. Thorax. 2010;65: 619-25.
    • (2010) Thorax. , vol.65 , pp. 619-625
    • Gelb, A.F.1    George, S.C.2    Silkoff, P.E.3    Krishnan, A.4    Fraser, C.5    Taylor, C.F.6
  • 70
    • 20444506757 scopus 로고    scopus 로고
    • Alveolar nitric oxide in adults with asthma: Evidence of distal lung infl ammation in refractory asthma
    • Berry M, Hargadon B, Morgan A, Shelley M, Richter J, Shaw D, et al. Alveolar nitric oxide in adults with asthma: evidence of distal lung infl ammation in refractory asthma. Eur Respir J. 2005;25:986-91.
    • (2005) Eur Respir J. , vol.25 , pp. 986-991
    • Berry, M.1    Hargadon, B.2    Morgan, A.3    Shelley, M.4    Richter, J.5    Shaw, D.6
  • 71
    • 33646264353 scopus 로고    scopus 로고
    • Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma
    • van Veen IH, Sterk PJ, Schot R, Gauw SA, Rabe KF, Bel EH. Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma. Eur Respir J. 2006; 27:951-6.
    • (2006) Eur Respir J. , vol.27 , pp. 951-956
    • Van Veen, I.H.1    Sterk, P.J.2    Schot, R.3    Gauw, S.A.4    Rabe, K.F.5    Bel, E.H.6
  • 73
    • 77957770034 scopus 로고    scopus 로고
    • Acinar effect of inhaled steroids evidenced by exhaled nitric oxide
    • Van Muylem A, Kerckx Y, Michils A. Acinar effect of inhaled steroids evidenced by exhaled nitric oxide. J Allergy Clin Immunol. 2010;126:730-5.
    • (2010) J Allergy Clin Immunol. , vol.126 , pp. 730-735
    • Van Muylem, A.1    Kerckx, Y.2    Michils, A.3
  • 74
    • 34547807610 scopus 로고    scopus 로고
    • Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway infl ammation
    • Downie SR, Salome CM, Verbanck S, Thompson B, Berend N, King GG. Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway infl ammation. Thorax. 2007;62:684-9.
    • (2007) Thorax. , vol.62 , pp. 684-689
    • Downie, S.R.1    Salome, C.M.2    Verbanck, S.3    Thompson, B.4    Berend, N.5    King, G.G.6
  • 75
    • 0022341248 scopus 로고
    • Convection-and diffusion-dependent ventilation maldistribution in normal subjects
    • Crawford AB, Makowska M, Paiva M, Engel LA. Convection-and diffusion-dependent ventilation maldistribution in normal subjects. J Appl Physiol. 1985;59:838-46.
    • (1985) J Appl Physiol. , vol.59 , pp. 838-846
    • Crawford, A.B.1    Makowska, M.2    Paiva, M.3    Engel, L.A.4
  • 78
    • 0037378424 scopus 로고    scopus 로고
    • Nonreversible conductive airway ventilation heterogeneity in mild asthma
    • Verbanck S, Schuermans D, Paiva M, Vincken W. Nonreversible conductive airway ventilation heterogeneity in mild asthma. J Appl Physiol. 2003;94:1380-6.
    • (2003) J Appl Physiol. , vol.94 , pp. 1380-1386
    • Verbanck, S.1    Schuermans, D.2    Paiva, M.3    Vincken, W.4
  • 79
    • 77649271741 scopus 로고    scopus 로고
    • Infl ammation and airway function in the lung periphery of patients with stable asthma
    • Verbanck S, Schuermans D, Vincken W. Infl ammation and airway function in the lung periphery of patients with stable asthma. J Allergy Clin Immunol. 2010;125:611-6.
    • (2010) J Allergy Clin Immunol. , vol.125 , pp. 611-616
    • Verbanck, S.1    Schuermans, D.2    Vincken, W.3
  • 80
    • 33749865124 scopus 로고    scopus 로고
    • Small airway function improvement after smoking cessation in smokers without airway obstruction
    • Verbanck S, Schuermans D, Paiva M, Meysman M, Vincken W. Small airway function improvement after smoking cessation in smokers without airway obstruction. Am J Respir Crit Care Med. 2006;174:853-7.
    • (2006) Am J Respir Crit Care Med. , vol.174 , pp. 853-857
    • Verbanck, S.1    Schuermans, D.2    Paiva, M.3    Meysman, M.4    Vincken, W.5
  • 81
    • 23744448863 scopus 로고    scopus 로고
    • Clinical applications of forced oscillation to assess peripheral airway function
    • Goldman MD, Saadeh C, Ross D. Clinical applications of forced oscillation to assess peripheral airway function. Respir Physiol Neurobiol. 2005;148:179-94.
    • (2005) Respir Physiol Neurobiol. , vol.148 , pp. 179-194
    • Goldman, M.D.1    Saadeh, C.2    Ross, D.3
  • 83
    • 77949791521 scopus 로고    scopus 로고
    • Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease
    • Paredi P, Goldman M, Alamen A, Ausin P, Usmani OS, Pride NB, et al. Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease. Thorax. 2010;65:263-7.
    • (2010) Thorax. , vol.65 , pp. 263-267
    • Paredi, P.1    Goldman, M.2    Alamen, A.3    Ausin, P.4    Usmani, O.S.5    Pride, N.B.6
  • 84
    • 78651334110 scopus 로고    scopus 로고
    • Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease
    • Muskulus M, Slats AM, Sterk PJ, Verduyn-Lunel S. Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease. J Appl Physiol. 2010;109:1582-91.
    • (2010) J Appl Physiol. , vol.109 , pp. 1582-1591
    • Muskulus, M.1    Slats, A.M.2    Sterk, P.J.3    Verduyn-Lunel, S.4
  • 85
    • 0027159864 scopus 로고
    • Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airfl ow obstruction
    • Melchor R, Biddiscombe MF, Mak VH, Short MD, Spiro SG. Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airfl ow obstruction. Thorax. 1993;48:506-11.
    • (1993) Thorax. , vol.48 , pp. 506-511
    • Melchor, R.1    Biddiscombe, M.F.2    Mak, V.H.3    Short, M.D.4    Spiro, S.G.5
  • 86
    • 0035117761 scopus 로고    scopus 로고
    • The infl uence of lung deposition on clinical response
    • Pritchard JN. The infl uence of lung deposition on clinical response. J Aerosol Med. 2001;14:S19-26.
    • (2001) J Aerosol Med. , vol.14
    • Pritchard, J.N.1
  • 87
    • 46149087663 scopus 로고    scopus 로고
    • accessed 13 December 2010
    • Global Initiative for Asthma (GINA). 2008. Available at: http://www.ginasthma.org/(accessed 13 December 2010).
    • (2008) Global Initiative for Asthma (GINA)
  • 88
    • 34548660457 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176:532-55.
    • (2007) Am J Respir Crit Care Med. , vol.176 , pp. 532-555
    • Rabe, K.F.1    Hurd, S.2    Anzueto, A.3    Barnes, P.J.4    Buist, S.A.5    Calverley, P.6
  • 90
    • 48449100901 scopus 로고    scopus 로고
    • Effect of fl uticasone 250 microg/salmeterol 50 microg and montelukast on exhaled nitric oxide in asthmatic patients
    • Gelb AF, Taylor CF, Shinar CM, Gutierrez CA, Zamel N. Effect of fl uticasone 250 microg/salmeterol 50 microg and montelukast on exhaled nitric oxide in asthmatic patients. Can Respir J. 2008;15:193-8.
    • (2008) Can Respir J. , vol.15 , pp. 193-198
    • Gelb, A.F.1    Taylor, C.F.2    Shinar, C.M.3    Gutierrez, C.A.4    Zamel, N.5
  • 91
    • 58249092645 scopus 로고    scopus 로고
    • The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma
    • Fritscher LG, Rodrigues MT, Zamel N, Chapman KR. The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma. Respir Med. 2009;103:296-300.
    • (2009) Respir Med. , vol.103 , pp. 296-300
    • Fritscher, L.G.1    Rodrigues, M.T.2    Zamel, N.3    Chapman, K.R.4
  • 92
    • 30444452988 scopus 로고    scopus 로고
    • Regional lung deposition and bronchodilator response as a function of β2-agonist particle size
    • Usmani OS, Biddiscombe MF, Barnes PJ. Regional lung deposition and bronchodilator response as a function of β2-agonist particle size. Am J Respir Crit Care Med. 2005; 172:1497-504.
    • (2005) Am J Respir Crit Care Med. , vol.172 , pp. 1497-504
    • Usmani, O.S.1    Biddiscombe, M.F.2    Barnes, P.J.3
  • 93
    • 32644435870 scopus 로고    scopus 로고
    • High lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma
    • Newman S, Salmon A, Nave R, Drollmann A. High lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma. Respir Med. 2006; 100:375-84.
    • (2006) Respir Med. , vol.100 , pp. 375-384
    • Newman, S.1    Salmon, A.2    Nave, R.3    Drollmann, A.4
  • 94
    • 0036036475 scopus 로고    scopus 로고
    • Lung deposition of hydrofl uoroalkane-134a beclomethasone is greater than that of chlorofl uorocarbon fl uticasone and chlorofl uorocarbon beclomethasone: A cross-over study in healthy volunteers
    • Leach CL, Davidson PJ, Hasselquist BE, Boudreau RJ. Lung deposition of hydrofl uoroalkane-134a beclomethasone is greater than that of chlorofl uorocarbon fl uticasone and chlorofl uorocarbon beclomethasone: a cross-over study in healthy volunteers. Chest. 2002;122:510-6.
    • (2002) Chest. , vol.122 , pp. 510-516
    • Leach, C.L.1    Davidson, P.J.2    Hasselquist, B.E.3    Boudreau, R.J.4
  • 95
    • 0033431716 scopus 로고    scopus 로고
    • Effi cacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant
    • Busse WW, Brazinsky S, Jacobson K, Stricker W, Schmitt K, Vanden Burgt J, et al. Effi cacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant. J Allergy Clin Immunol. 1999;104:1215-22.
    • (1999) J Allergy Clin Immunol. , vol.104 , pp. 1215-1222
    • Busse, W.W.1    Brazinsky, S.2    Jacobson, K.3    Stricker, W.4    Schmitt, K.5    Vanden Burgt, J.6
  • 97
    • 34147160761 scopus 로고    scopus 로고
    • Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma
    • Papi A, Paggiaro PL, Nicolini G, Vignola AM, Fabbri LM. Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma. Eur Respir J. 2007;29: 682-9.
    • (2007) Eur Respir J. , vol.29 , pp. 682-689
    • Papi, A.1    Paggiaro, P.L.2    Nicolini, G.3    Vignola, A.M.4    Fabbri, L.M.5
  • 98
    • 34548484562 scopus 로고    scopus 로고
    • Beclomethasone/formoterol vs fl uticasone/salmeterol inhaled combination in moderate to severe asthma
    • Papi A, Paggiaro P, Nicolini G, Vignola AM, Fabbri LM. Beclomethasone/formoterol vs fl uticasone/salmeterol inhaled combination in moderate to severe asthma. Allergy. 2007; 62:1182-8.
    • (2007) Allergy. , vol.62 , pp. 1182-1188
    • Papi, A.1    Paggiaro, P.2    Nicolini, G.3    Vignola, A.M.4    Fabbri, L.M.5
  • 99
    • 67349245921 scopus 로고    scopus 로고
    • Effect of inhaled corticosteroids on small airways in asthma: Investigation using impulse oscillometry
    • Yamaguchi M, Niimi A, Ueda T, Takemura M, Matsuoka H, Jinnai M, et al. Effect of inhaled corticosteroids on small airways in asthma: investigation using impulse oscillometry. Pulm Pharmacol Ther. 2009;22:326-32.
    • (2009) Pulm Pharmacol Ther. , vol.22 , pp. 326-332
    • Yamaguchi, M.1    Niimi, A.2    Ueda, T.3    Takemura, M.4    Matsuoka, H.5    Jinnai, M.6
  • 100
    • 77949663450 scopus 로고    scopus 로고
    • Comparison of effectiveness in ciclesonide and fl uticasone propionate on small airway function in mild asthma
    • Hoshino M. Comparison of effectiveness in ciclesonide and fl uticasone propionate on small airway function in mild asthma. Allergol Int. 2010;59:59-66.
    • (2010) Allergol Int. , vol.59 , pp. 59-66
    • Hoshino, M.1
  • 101
    • 33746563608 scopus 로고    scopus 로고
    • The functional benefi t of anti-infl ammatory aerosols in the lung periphery
    • Verbanck S, Schuermans D, Paiva M, Vincken W. The functional benefi t of anti-infl ammatory aerosols in the lung periphery. J Allergy Clin Immunol. 2006;118:340-6.
    • (2006) J Allergy Clin Immunol. , vol.118 , pp. 340-346
    • Verbanck, S.1    Schuermans, D.2    Paiva, M.3    Vincken, W.4
  • 104
    • 0032879891 scopus 로고    scopus 로고
    • Optimizing the in vitro performance of Respimat
    • Zierenberg B. Optimizing the in vitro performance of Respimat. J Aerosol Med. 1999;1:S19-24.
    • (1999) J Aerosol Med. , vol.1
    • Zierenberg, B.1
  • 105
    • 0031977041 scopus 로고    scopus 로고
    • Lung deposition of fenoterol and fl unisolide delivered using a novel device for inhaled medicines
    • Newman SP, Brown J, Steed SP, Reader SJ, Kladders H. Lung deposition of fenoterol and fl unisolide delivered using a novel device for inhaled medicines. Chest. 1998;113:957-63.
    • (1998) Chest. , vol.113 , pp. 957-963
    • Newman, S.P.1    Brown, J.2    Steed, S.P.3    Reader, S.J.4    Kladders, H.5
  • 106
    • 25844450169 scopus 로고    scopus 로고
    • Deposition of corticosteroid aerosol in the human lung by Respimat ® Soft Mist ™ Inhaler compared to deposition by metered dose inhaler or by Turbuhaler ® dry powder inhaler
    • Pitcairn G, Reader R, Pavia D, Newman S. Deposition of corticosteroid aerosol in the human lung by Respimat ® Soft Mist ™ Inhaler compared to deposition by metered dose inhaler or by Turbuhaler ® dry powder inhaler. J Aerosol Med. 2005;18:264-72.
    • (2005) J Aerosol Med. , vol.18 , pp. 264-272
    • Pitcairn, G.1    Reader, R.2    Pavia, D.3    Newman, S.4
  • 107
    • 60249098195 scopus 로고    scopus 로고
    • Higher lung deposition with respimat soft mist inhaler than HFA-MDI in COPD patients with poor technique
    • Brand P, Hederer B, Austen G, Dewberry H, Meyer T. Higher lung deposition with Respimat Soft Mist inhaler than HFA-MDI in COPD patients with poor technique. Int J Chron Obstruct Pulmon Dis. 2008;3:763-70.
    • (2008) Int J Chron Obstruct Pulmon Dis. , vol.3 , pp. 763-770
    • Brand, P.1    Hederer, B.2    Austen, G.3    Dewberry, H.4    Meyer, T.5
  • 108
    • 34648819502 scopus 로고    scopus 로고
    • Lung deposition of radiolabeled tiotropium in healthy subjects and patients with chronic obstructive pulmonary disease
    • Brand P, Meyer T, Weuthen T, Timmer W, Berkel E, Wallenstein G, et al. Lung deposition of radiolabeled tiotropium in healthy subjects and patients with chronic obstructive pulmonary disease. J Clin Pharmacol. 2007;47:1335-41.
    • (2007) J Clin Pharmacol. , vol.47 , pp. 1335-1341
    • Brand, P.1    Meyer, T.2    Weuthen, T.3    Timmer, W.4    Berkel, E.5    Wallenstein, G.6
  • 109
    • 73749084119 scopus 로고    scopus 로고
    • Tiotropium 5microg via Respimat and 18microg via HandiHaler; Effi cacy and safety in Japanese COPD patients
    • Ichinose M, Fujimoto T, Fukuchi Y. Tiotropium 5microg via Respimat and 18microg via HandiHaler; effi cacy and safety in Japanese COPD patients. Respir Med. 2010;104: 228-36.
    • (2010) Respir Med. , vol.104 , pp. 228-236
    • Ichinose, M.1    Fujimoto, T.2    Fukuchi, Y.3
  • 110
    • 77956712835 scopus 로고    scopus 로고
    • The safety of tiotropium-the FDA ' s conclusions
    • Michele TM, Pinheiro S, Iyasu S. The safety of tiotropium-the FDA ' s conclusions. N Engl J Med. 2010;363:1097-9.
    • (2010) N Engl J Med. , vol.363 , pp. 1097-1099
    • Michele, T.M.1    Pinheiro, S.2    Iyasu, S.3


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