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Volumn 48, Issue 6, 2015, Pages 1147-1157

Distribution of aerosolized particles in healthy and emphysematous rat lungs: Comparison between experimental and numerical studies

Author keywords

Aerosol exposure experiments; Airflow; Computational fluid dynamics; Multi scale; Particle deposition

Indexed keywords

AEROSOLS; COMPUTATIONAL FLUID DYNAMICS; DEPOSITION RATES; FORECASTING; GEOMETRY; RATS;

EID: 84925363302     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2015.01.004     Document Type: Article
Times cited : (27)

References (35)
  • 1
    • 77957178470 scopus 로고
    • A multiple path model of particle deposition in the rat lung
    • Anjilvel S., Asgharian B. A multiple path model of particle deposition in the rat lung. Fundam. Appl. Toxiocol. 1995, 28:41-50.
    • (1995) Fundam. Appl. Toxiocol. , vol.28 , pp. 41-50
    • Anjilvel, S.1    Asgharian, B.2
  • 2
    • 33748970673 scopus 로고    scopus 로고
    • Prediction of particle deposition in the human lung using realistic models of lung ventilation
    • Asgharian B., Price O.T., Hofmann W. Prediction of particle deposition in the human lung using realistic models of lung ventilation. J. Aerosol Sci. 2006, 37:1209-1221.
    • (2006) J. Aerosol Sci. , vol.37 , pp. 1209-1221
    • Asgharian, B.1    Price, O.T.2    Hofmann, W.3
  • 4
    • 69249120315 scopus 로고    scopus 로고
    • Lung deposition of inhaled alpha1-proteinase inhibitor in cystic fibrosis and alpha1-antitrypsin deficiency
    • Brand P., Schulte M., Wencker M., Herpich C.H., Klein G., Hanna K., Meyer T. Lung deposition of inhaled alpha1-proteinase inhibitor in cystic fibrosis and alpha1-antitrypsin deficiency. Eur. Respir. J. 2009, 34:354-360.
    • (2009) Eur. Respir. J. , vol.34 , pp. 354-360
    • Brand, P.1    Schulte, M.2    Wencker, M.3    Herpich, C.H.4    Klein, G.5    Hanna, K.6    Meyer, T.7
  • 5
    • 0028598342 scopus 로고
    • One-dimensional simulation of aerosol transport and deposition in the human lung
    • Darquenne C., Paiva M. One-dimensional simulation of aerosol transport and deposition in the human lung. J. Appl. Physiol. 1994, 77:2889-2898.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 2889-2898
    • Darquenne, C.1    Paiva, M.2
  • 8
    • 79251518313 scopus 로고    scopus 로고
    • Regional correlation of emphysematous changes in lung function and structure. a comparison between pulmonary function testing and hyperpolarized MRI metrics
    • Emami K., Chia E., Kadlecek S., Macduffie-Woodburn J.P., Zhu J., Pickup S., Blum A., Ishii M., Rizi R.R. Regional correlation of emphysematous changes in lung function and structure. a comparison between pulmonary function testing and hyperpolarized MRI metrics. J. Appl. Physiol. 2011, 110:225-235.
    • (2011) J. Appl. Physiol. , vol.110 , pp. 225-235
    • Emami, K.1    Chia, E.2    Kadlecek, S.3    Macduffie-Woodburn, J.P.4    Zhu, J.5    Pickup, S.6    Blum, A.7    Ishii, M.8    Rizi, R.R.9
  • 9
    • 84882340420 scopus 로고    scopus 로고
    • A new preconditioning technique for implicitly coupled multidomain simulations with applications to hemodynamics
    • Esmaily Moghadam M., Basikevs Y., Marsden A.L. A new preconditioning technique for implicitly coupled multidomain simulations with applications to hemodynamics. Comput. Mech. 2013, 52:1141-1152.
    • (2013) Comput. Mech. , vol.52 , pp. 1141-1152
    • Esmaily Moghadam, M.1    Basikevs, Y.2    Marsden, A.L.3
  • 10
    • 80052689076 scopus 로고    scopus 로고
    • A comparison of outlet boundary treatments for prevention of backflow divergence with relevance to blood flow simulations
    • Esmaily Moghadam M., Bazilevs Y., Hsia T.-Y., Vignon-Clementel I.E., Marsden A.L. A comparison of outlet boundary treatments for prevention of backflow divergence with relevance to blood flow simulations. Comput. Mech. 2011, 48:277-291.
    • (2011) Comput. Mech. , vol.48 , pp. 277-291
    • Esmaily Moghadam, M.1    Bazilevs, Y.2    Hsia, T.-Y.3    Vignon-Clementel, I.E.4    Marsden, A.L.5
  • 11
    • 84878473416 scopus 로고    scopus 로고
    • A modular numerical method for implicit 0D/3D coupling in cardiovascular finite element simulations
    • Esmaily Moghadam M., Vignon-Clementel I.E., Figliola R., Marsden A.L. A modular numerical method for implicit 0D/3D coupling in cardiovascular finite element simulations. J. Comput. Phys. 2013, 244:63-79.
    • (2013) J. Comput. Phys. , vol.244 , pp. 63-79
    • Esmaily Moghadam, M.1    Vignon-Clementel, I.E.2    Figliola, R.3    Marsden, A.L.4
  • 12
    • 84879033787 scopus 로고    scopus 로고
    • Dynamic multiscale boundary conditions for 4D CT of healthy and emphysematous rats
    • Jacob R.E., Carson J.P., Thomas M., Einstein D.R. Dynamic multiscale boundary conditions for 4D CT of healthy and emphysematous rats. PloS one 2013, 8:e65874.
    • (2013) PloS one , vol.8
    • Jacob, R.E.1    Carson, J.P.2    Thomas, M.3    Einstein, D.R.4
  • 13
    • 84879219236 scopus 로고    scopus 로고
    • Controlled parametric individualized 2D and 3D imaging measurements of aerosol deposition in the respiratory tract of healthy human subjects: preliminary comparisons with simulations
    • Katz I., Pichelin M., Caillibotte G., Montesantos S., Majoral C., Martonen T., Fleming J., Bennett M., Conway J. Controlled parametric individualized 2D and 3D imaging measurements of aerosol deposition in the respiratory tract of healthy human subjects: preliminary comparisons with simulations. Aerosol Sci. Technol. 2013, 47:714-723.
    • (2013) Aerosol Sci. Technol. , vol.47 , pp. 714-723
    • Katz, I.1    Pichelin, M.2    Caillibotte, G.3    Montesantos, S.4    Majoral, C.5    Martonen, T.6    Fleming, J.7    Bennett, M.8    Conway, J.9
  • 14
    • 84862649849 scopus 로고    scopus 로고
    • Comparing MDI and DPI aerosol deposition using in vitro experiments and a new stochastic individual path (SIP) model of the conducting airways
    • Longest P.W., Tian G., Walenga R.L., Hindle M. Comparing MDI and DPI aerosol deposition using in vitro experiments and a new stochastic individual path (SIP) model of the conducting airways. Pharm. Res. 2012, 29:1670-1688.
    • (2012) Pharm. Res. , vol.29 , pp. 1670-1688
    • Longest, P.W.1    Tian, G.2    Walenga, R.L.3    Hindle, M.4
  • 15
    • 58549098521 scopus 로고    scopus 로고
    • CFD simulation of aerosol deposition in an anatomically based human large-medium airway model
    • Ma B., Lutchen K.R. CFD simulation of aerosol deposition in an anatomically based human large-medium airway model. Ann. Biomed. Eng. 2009, 37:271-285.
    • (2009) Ann. Biomed. Eng. , vol.37 , pp. 271-285
    • Ma, B.1    Lutchen, K.R.2
  • 16
    • 64849103256 scopus 로고    scopus 로고
    • CFD simulation and experimental validation of fluid flow and particle transport in a model of alveolated airways
    • Ma B., Ruwet V., Corieri P., Theunissen R., Riethmuller M., Darquenne C. CFD simulation and experimental validation of fluid flow and particle transport in a model of alveolated airways. J. Aerosol Sci. 2009, 40:403-414.
    • (2009) J. Aerosol Sci. , vol.40 , pp. 403-414
    • Ma, B.1    Ruwet, V.2    Corieri, P.3    Theunissen, R.4    Riethmuller, M.5    Darquenne, C.6
  • 19
    • 67649464214 scopus 로고    scopus 로고
    • Validation of computational fluid dynamics methodology used for human upper airway flow simulations
    • Mylavarapu G., Murugappan S., Mihaescu M., Kalra M., Khosla S., Gutmark E. Validation of computational fluid dynamics methodology used for human upper airway flow simulations. J. Biomech. 2009, 42:1553-1559.
    • (2009) J. Biomech. , vol.42 , pp. 1553-1559
    • Mylavarapu, G.1    Murugappan, S.2    Mihaescu, M.3    Kalra, M.4    Khosla, S.5    Gutmark, E.6
  • 20
    • 84902479914 scopus 로고    scopus 로고
    • MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats
    • Oakes J.M., Breen E., Scadeng M., Tchantchou G.S., Darquenne C. MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats. J. Appl. Physiol. 2014, 116:1561-1568.
    • (2014) J. Appl. Physiol. , vol.116 , pp. 1561-1568
    • Oakes, J.M.1    Breen, E.2    Scadeng, M.3    Tchantchou, G.S.4    Darquenne, C.5
  • 21
    • 77953593056 scopus 로고    scopus 로고
    • Flow field analysis in expanding healthy and emphysematous alveolar models using particle image velocimetry
    • 021008-1-9
    • Oakes J.M., Day S., Weinstein S.J., Robinson R.J. Flow field analysis in expanding healthy and emphysematous alveolar models using particle image velocimetry. J. Biomech. Eng. 2010, 132. 021008-1-9.
    • (2010) J. Biomech. Eng. , vol.132
    • Oakes, J.M.1    Day, S.2    Weinstein, S.J.3    Robinson, R.J.4
  • 24
    • 84876482615 scopus 로고    scopus 로고
    • Regional distribution of aerosol deposition in rat lungs using magnetic resonance imaging
    • Oakes J.M., Scadeng M., Breen E.C., Prisk G.K., Darquenne C. Regional distribution of aerosol deposition in rat lungs using magnetic resonance imaging. Ann. Biomed. Eng. 2013, 41:967-978.
    • (2013) Ann. Biomed. Eng. , vol.41 , pp. 967-978
    • Oakes, J.M.1    Scadeng, M.2    Breen, E.C.3    Prisk, G.K.4    Darquenne, C.5
  • 25
    • 0014805519 scopus 로고
    • The prediction of pressure drop and variation of resistance within the human bronchial airways
    • Pedley T.J., Schroter R.C., Sudlow M.F. The prediction of pressure drop and variation of resistance within the human bronchial airways. Respir. Physiol. 1970, 9:387-405.
    • (1970) Respir. Physiol. , vol.9 , pp. 387-405
    • Pedley, T.J.1    Schroter, R.C.2    Sudlow, M.F.3
  • 26
    • 83555164872 scopus 로고    scopus 로고
    • Flow and volume dependence of rat airway resistance during constant flow inflation and deflation
    • Rubini A., Carniel E.L., Parmagnani A., Natali A.N. Flow and volume dependence of rat airway resistance during constant flow inflation and deflation. Lung 2011, 189:511-518.
    • (2011) Lung , vol.189 , pp. 511-518
    • Rubini, A.1    Carniel, E.L.2    Parmagnani, A.3    Natali, A.N.4
  • 27
    • 54949126753 scopus 로고    scopus 로고
    • Model for the deposition of aerosol particles in the respiratory tract of the rat. I. Nonhygroscopic particle deposition
    • Schmid O., Bolle I., Harder V., Karg E., Takenaka S., Schulz H., Ferron G.A. Model for the deposition of aerosol particles in the respiratory tract of the rat. I. Nonhygroscopic particle deposition. J. Aerosol Med. Pulm. Drug Deliv. 2008, 21:291-307.
    • (2008) J. Aerosol Med. Pulm. Drug Deliv. , vol.21 , pp. 291-307
    • Schmid, O.1    Bolle, I.2    Harder, V.3    Karg, E.4    Takenaka, S.5    Schulz, H.6    Ferron, G.A.7
  • 30
    • 0023188202 scopus 로고
    • Emphysema alters the deposition pattern of inhaled particles in hamsters
    • Sweeney T.D., Brain J.D., Leavitt S.A., Godleski J.J. Emphysema alters the deposition pattern of inhaled particles in hamsters. Am. J. Pathol. 1987, 128:19-28.
    • (1987) Am. J. Pathol. , vol.128 , pp. 19-28
    • Sweeney, T.D.1    Brain, J.D.2    Leavitt, S.A.3    Godleski, J.J.4
  • 31
    • 0027942484 scopus 로고
    • Emphysema. definition, imaging, and quantification
    • Thurlbeck W.M., Muller N.L. Emphysema. definition, imaging, and quantification. Am. J. Roentgenol. 1994, 163:1017-1025.
    • (1994) Am. J. Roentgenol. , vol.163 , pp. 1017-1025
    • Thurlbeck, W.M.1    Muller, N.L.2
  • 33
    • 0002530487 scopus 로고
    • Bronchial atrophy and collapse in chronic obstructive pulmonary emphysema
    • Wright R.R. Bronchial atrophy and collapse in chronic obstructive pulmonary emphysema. Am. J. Pathol. 1960, 37:63-77.
    • (1960) Am. J. Pathol. , vol.37 , pp. 63-77
    • Wright, R.R.1
  • 34
    • 0018728405 scopus 로고
    • Anatomic models of the tracheobronchial and pulmonary regions of the rat
    • Yeh H.C., Schum G.M., Duggan M.T. Anatomic models of the tracheobronchial and pulmonary regions of the rat. Anat. Record 1979, 195:483-492.
    • (1979) Anat. Record , vol.195 , pp. 483-492
    • Yeh, H.C.1    Schum, G.M.2    Duggan, M.T.3
  • 35
    • 0035013945 scopus 로고    scopus 로고
    • Effect of particle inlet distributions on deposition in a triple bifurcation lung airway model
    • Zhang Z., Kleinstreuer C. Effect of particle inlet distributions on deposition in a triple bifurcation lung airway model. J. Aerosol Med. 2001, 14:13-29.
    • (2001) J. Aerosol Med. , vol.14 , pp. 13-29
    • Zhang, Z.1    Kleinstreuer, C.2


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