Condensational growth of combination drug-excipient submicrometer particles for targeted high efficiency pulmonary delivery: Comparison of CFD predictions with experimental results

Pharmaceutical Research

Volumn 29, Issue 3, 2012, Pages 707-721

  Longest, P Worth ^a   Hindle, Michael ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Engineered combination particles; Enhanced excipient growth (EEG); Hygroscopic aerosol growth; Nanoaerosols; Respiratory drug delivery

Indexed keywords

BUDESONIDE; BRONCHODILATING AGENT; EXCIPIENT;

AEROSOL; ARTICLE; CHEMICAL PARAMETERS; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DESIGN; ENHANCED EXCIPIENT GROWTH; EXCIPIENT COMPATIBILITY; HUMIDITY; HYGROSCOPIC GROWTH; IN VITRO STUDY; METERED DOSE INHALER; PARTICLE SIZE; PHYSICAL PARAMETERS; PRIORITY JOURNAL; RESPIRATORY DRUG DELIVERY; THERMODYNAMICS; WETTABILITY; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; HYDRODYNAMICS; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM; NEBULIZER;

ADMINISTRATION, INHALATION; AEROSOLS; BRONCHODILATOR AGENTS; BUDESONIDE; COMPUTER SIMULATION; EXCIPIENTS; HUMIDITY; HYDRODYNAMICS; LUNG; MODELS, CHEMICAL; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE;

EID: 84861927754     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0596-1     Document Type: Article

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