An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms

Nature Communications

Volumn 4, Issue , 2013, Pages

  Rauh, David ^a   Fischer, Frank ^b   Gertz, Melanie ^b   Lakshminarasimhan, Mahadevan ^b,g   Bergbrede, Tim ^c   Aladini, Firouzeh ^d,e   Kambach, Christian ^b   Becker, Christian F W ^d,e   Zerweck, Johannes ^f   Schutkowski, Mike ^a   Steegborn, Clemens ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c Lead Discovery Center GmbH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF VIENNA   (Austria)

^f JPT Peptide Technologies GmbH   (Germany)

^g STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; ISOENZYME; MALATE DEHYDROGENASE; PEROXIREDOXIN 1; SIRTUIN; SIRTUIN 1; SIRTUIN 4; SIRTUIN 5;

ACETYLENE; ARRAY; ENZYME ACTIVITY; METABOLISM; MOBILITY; PEPTIDE; SUBSTRATE;

ACETYLATION; ARTICLE; BINDING SITE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHROMOSOME SEGREGATION; COMPARATIVE STUDY; CONTROLLED STUDY; DEACETYLATION; ENZYME MODIFICATION; FLUORESCENCE; HUMAN; LIPID METABOLISM; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PEPTIDE MICROARRAY; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION;

ACETYLATION; AMINO ACID SEQUENCE; BINDING SITES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN ARRAY ANALYSIS; PROTEIN ISOFORMS; PROTEOME; SIGNAL TRANSDUCTION; SIRTUINS; SUBSTRATE SPECIFICITY;

EID: 84884163378     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3327     Document Type: Article

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