Kinetic dissection of the pre-existing conformational equilibrium in the trypsin fold

Journal of Biological Chemistry

Volumn 290, Issue 37, 2015, Pages 22435-22445

  Vogt, Austin D ^a   Chakraborty, Pradipta ^a   Di Cera, Enrico ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINETICS; LIGANDS;

CONFORMATIONAL EQUILIBRIUM; CONFORMATIONAL PLASTICITY; CONFORMATIONAL TRANSITIONS; LIGAND RECOGNITION; OPEN CONFORMATION; STOPPED-FLOW KINETICS; STRUCTURAL BIOLOGY; ZYMOGEN ACTIVATION;

ENZYMES;

ENZYME PRECURSOR; PRETHROMBIN 2; PROTEINASE; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG; PRETHROMBINS; PROTHROMBIN;

ARTICLE; CHEMICAL MODIFICATION; CONFORMATIONAL EQUILIBRIUM; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; FLOW KINETICS; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE;

HUMANS; KINETICS; MODELS, MOLECULAR; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN; TRYPSIN;

EID: 84941585676     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.675538     Document Type: Article

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