Activation of protein C by the thrombin-thrombomodulin complex: Cooperative roles of Arg-35 of thrombin and Arg-67 of protein C

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 4, 2006, Pages 879-884

  Yang, Likui ^a   Manithody, Chandrashekhara ^a   Rezaie, Alireza R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALCIUM ION; PROTEIN C; THROMBIN; THROMBOMODULIN;

AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM BINDING; COMPLEX FORMATION; CONTROLLED STUDY; DISULFIDE BOND; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYDROGEN BOND; MUTANT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ALANINE; ANTITHROMBINS; ARGININE; BINDING SITES; CALCIUM; CATALYTIC DOMAIN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; KINETICS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN C; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THROMBIN; RECOMBINANT PROTEINS; THROMBIN; THROMBOMODULIN; TIME FACTORS;

EID: 32244444849     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507700103     Document Type: Article

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