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Volumn 30, Issue 5, 2015, Pages 1093-1104

Blood–brain barrier dysfunction following traumatic brain injury

Author keywords

Blood brain barrier; Brain edema; Central nervous system trauma; Traumatic brain injury; Vascular permeability

Indexed keywords

TIGHT JUNCTION PROTEIN; ZONULA OCCLUDENS PROTEIN;

EID: 84941182064     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-015-9651-7     Document Type: Review
Times cited : (114)

References (129)
  • 1
    • 17644364388 scopus 로고    scopus 로고
    • Dynamics of CNS barriers: evolution, differentiation, and modulation
    • PID: 1596250
    • Abbott NJ (2005) Dynamics of CNS barriers: evolution, differentiation, and modulation. Cell Mol Neurobiol 25:5–23
    • (2005) Cell Mol Neurobiol , vol.25 , pp. 5-23
    • Abbott, N.J.1
  • 2
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood–brain barrier
    • COI: 1:CAS:528:DC%2BD2MXhtlaktbjP, PID: 1637194
    • Abbott NJ, Rönnbäck L, Hansson E (2006) Astrocyte-endothelial interactions at the blood–brain barrier. Nat Rev Neurosci 7:41–53
    • (2006) Nat Rev Neurosci , vol.7 , pp. 41-53
    • Abbott, N.J.1    Rönnbäck, L.2    Hansson, E.3
  • 3
    • 70449529433 scopus 로고    scopus 로고
    • Structure and function of the blood–brain barrier
    • COI: 1:CAS:528:DC%2BD1MXhsVGms73P, PID: 1966471
    • Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ (2010) Structure and function of the blood–brain barrier. Neurobiol Dis 37:13–25. doi:10.1016/j.nbd.2009.07.030
    • (2010) Neurobiol Dis , vol.37 , pp. 13-25
    • Abbott, N.J.1    Patabendige, A.A.2    Dolman, D.E.3    Yusof, S.R.4    Begley, D.J.5
  • 4
    • 84875983143 scopus 로고    scopus 로고
    • Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast
    • COI: 1:CAS:528:DC%2BC3sXnsFSksbw%3D, PID: 2346655
    • Abdul-Muneer PM, Schuetz H, Wang F, Skotak M, Jones J, Gorantla S, Zimmerman MC, Chandra N, Haorah J (2013) Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast. Free Radic Biol Med 60:282–291
    • (2013) Free Radic Biol Med , vol.60 , pp. 282-291
    • Abdul-Muneer, P.M.1    Schuetz, H.2    Wang, F.3    Skotak, M.4    Jones, J.5    Gorantla, S.6    Zimmerman, M.C.7    Chandra, N.8    Haorah, J.9
  • 5
    • 79551646454 scopus 로고    scopus 로고
    • Astrocytes and pericytes differentially modulate blood–brain barrier characteristics during development and hypoxic insult
    • PID: 2082726
    • Al Ahmad A, Taboada CB, Gassmann M, Ogunshola OO (2011) Astrocytes and pericytes differentially modulate blood–brain barrier characteristics during development and hypoxic insult. J Cereb Blood Flow Metab 31:693–705. doi:10.1038/jcbfm.2010.148
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 693-705
    • Al Ahmad, A.1    Taboada, C.B.2    Gassmann, M.3    Ogunshola, O.O.4
  • 7
    • 77950627398 scopus 로고    scopus 로고
    • Physiology and function of the tight junction
    • PID: 2006609
    • Anderson JM, Van Itallie CM (2009) Physiology and function of the tight junction. Cold Spring Harb Perspect Biol 1:a002584. doi:10.1101/cshperspect.a002584
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. 002584
    • Anderson, J.M.1    Van Itallie, C.M.2
  • 8
    • 77956189161 scopus 로고    scopus 로고
    • B cells and autoantibodies: complex roles in CNS injury
    • COI: 1:CAS:528:DC%2BC3cXhtFals7rE, PID: 2069163
    • Ankeny DP, Popovich PG (2010) B cells and autoantibodies: complex roles in CNS injury. Trends Immunol 31:332–338. doi:10.1016/j.it.2010.06.006
    • (2010) Trends Immunol , vol.31 , pp. 332-338
    • Ankeny, D.P.1    Popovich, P.G.2
  • 9
    • 0036792090 scopus 로고    scopus 로고
    • Substance P antagonist blocks leakage and reduces activation of cytokine-stimulated rat brain endothelium
    • COI: 1:CAS:528:DC%2BD38Xns1aisrk%3D, PID: 1245803
    • Annunziata P, Cioni C, Santonini R, Paccagnini E (2002) Substance P antagonist blocks leakage and reduces activation of cytokine-stimulated rat brain endothelium. J Neuroimmunol 131:41–49
    • (2002) J Neuroimmunol , vol.131 , pp. 41-49
    • Annunziata, P.1    Cioni, C.2    Santonini, R.3    Paccagnini, E.4
  • 11
    • 80053615559 scopus 로고    scopus 로고
    • Blood–brain barrier integrity and breast cancer metastasis to the brain
    • Arshad F, Wang L, Sy C, Avraham S, Avraham HK (2010) Blood–brain barrier integrity and breast cancer metastasis to the brain. Patholo Res Int. doi:10.4061/2011/920509
    • (2010) Patholo Res Int
    • Arshad, F.1    Wang, L.2    Sy, C.3    Avraham, S.4    Avraham, H.K.5
  • 12
    • 2342471420 scopus 로고    scopus 로고
    • The blood–brain barrier: an overview: structure, regulation, and clinical implications
    • COI: 1:CAS:528:DC%2BD2cXjs1altL8%3D, PID: 1520725
    • Ballabh P, Braun A, Nedergaard M (2004) The blood–brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 16:1–13
    • (2004) Neurobiol Dis , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 13
    • 0032834596 scopus 로고    scopus 로고
    • Direct effects of endotoxin on the endothelium: barrier function and injury
    • COI: 1:CAS:528:DyaK1MXntFOms7Y%3D, PID: 1053258
    • Bannerman DD, Goldblum SE (1999) Direct effects of endotoxin on the endothelium: barrier function and injury. Lab Invest 79:1181–1199
    • (1999) Lab Invest , vol.79 , pp. 1181-1199
    • Bannerman, D.D.1    Goldblum, S.E.2
  • 14
    • 0029907438 scopus 로고    scopus 로고
    • Magnetic resonance imaging-monitored acute blood–brain barrier changes in experimental traumatic brain injury
    • COI: 1:STN:280:DyaK2s%2FotlGntA%3D%3D, PID: 892950
    • Barzo P, Marmarou A, Fatouros P, Corwin F, Dunbar J (1996) Magnetic resonance imaging-monitored acute blood–brain barrier changes in experimental traumatic brain injury. J Neurosurg 85:1113–1121
    • (1996) J Neurosurg , vol.85 , pp. 1113-1121
    • Barzo, P.1    Marmarou, A.2    Fatouros, P.3    Corwin, F.4    Dunbar, J.5
  • 15
    • 0031304168 scopus 로고    scopus 로고
    • Biphasic pathophysiological response of vasogenic and cellularedema in traumatic brain swelling
    • COI: 1:STN:280:DyaK1c%2FnvVamsQ%3D%3D, PID: 941629
    • Barzo P, Marmarou A, Fatouros P, Hayasaki K, Corwin F (1997a) Biphasic pathophysiological response of vasogenic and cellularedema in traumatic brain swelling. Acta Neurochir Suppl 70:119–122
    • (1997) Acta Neurochir Suppl , vol.70 , pp. 119-122
    • Barzo, P.1    Marmarou, A.2    Fatouros, P.3    Hayasaki, K.4    Corwin, F.5
  • 16
    • 0030693706 scopus 로고    scopus 로고
    • Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging
    • COI: 1:STN:280:DyaK1c%2FksVSmug%3D%3D, PID: 938440
    • Barzo P, Marmarou A, Fatouros P, Hayasaki K, Corwin F (1997b) Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging. J Neurosurg 87:900–907
    • (1997) J Neurosurg , vol.87 , pp. 900-907
    • Barzo, P.1    Marmarou, A.2    Fatouros, P.3    Hayasaki, K.4    Corwin, F.5
  • 17
    • 0343247794 scopus 로고    scopus 로고
    • The biphasic opening of the blood–brain barrier in the cortex and hippocampus after traumatic brain injury in rats
    • PID: 915363
    • Başkaya MK, Rao AM, Doğan A, Donaldson D, Dempsey RJ (1997) The biphasic opening of the blood–brain barrier in the cortex and hippocampus after traumatic brain injury in rats. Neurosci Lett 226:33–36
    • (1997) Neurosci Lett , vol.226 , pp. 33-36
    • Başkaya, M.K.1    Rao, A.M.2    Doğan, A.3    Donaldson, D.4    Dempsey, R.J.5
  • 19
    • 3042590902 scopus 로고    scopus 로고
    • Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis
    • COI: 1:CAS:528:DC%2BD2cXmtlCnu78%3D, PID: 1526933
    • Bazzoni G, Dejana E (2004) Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev 84:869–901
    • (2004) Physiol Rev , vol.84 , pp. 869-901
    • Bazzoni, G.1    Dejana, E.2
  • 20
    • 48249092633 scopus 로고    scopus 로고
    • All vertebrates started out with a glial blood–brain barrier 4–500 million years ago
    • PID: 1833879
    • Bundgaard M, Abbott NJ (2008) All vertebrates started out with a glial blood–brain barrier 4–500 million years ago. Glia 56:699–708. doi:10.1002/glia.20642
    • (2008) Glia , vol.56 , pp. 699-708
    • Bundgaard, M.1    Abbott, N.J.2
  • 22
    • 26844501218 scopus 로고    scopus 로고
    • Animal models of head trauma
    • PID: 1638930
    • Cernak I (2005) Animal models of head trauma. NeuroRx 2:410–422
    • (2005) NeuroRx , vol.2 , pp. 410-422
    • Cernak, I.1
  • 23
    • 76349094923 scopus 로고    scopus 로고
    • Traumatic brain injury: an overview of pathobiology with emphasis on military populations
    • PID: 1980946
    • Cernak I, Noble-Haeusslein LJ (2010) Traumatic brain injury: an overview of pathobiology with emphasis on military populations. J Cereb Blood Flow Metab 30:255–266
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 255-266
    • Cernak, I.1    Noble-Haeusslein, L.J.2
  • 24
    • 84883289525 scopus 로고    scopus 로고
    • Concepts and strategies for clinical management of blast-induced traumatic brain injury andposttraumatic stress disorder
    • COI: 1:CAS:528:DC%2BC3sXktlylug%3D%3
    • Chen Y, Huang W, Constantini S (2013) Concepts and strategies for clinical management of blast-induced traumatic brain injury andposttraumatic stress disorder. J Neuropsychiatry Clin Neurosci Spring 25:103–110. doi:10.1176/appi.neuropsych.12030058
    • (2013) J Neuropsychiatry Clin Neurosci Spring , vol.25 , pp. 103-110
    • Chen, Y.1    Huang, W.2    Constantini, S.3
  • 25
    • 84902077801 scopus 로고    scopus 로고
    • The incidence of critical-illness-related-corticosteroid-insufficiency is associated with severity of traumatic brain injury in adult rats
    • PID: 2481991
    • Chen X, Zhao Z, Chai Y, Luo L, Jiang R, Zhang J (2014) The incidence of critical-illness-related-corticosteroid-insufficiency is associated with severity of traumatic brain injury in adult rats. J Neurol Sci 342:93–100. doi:10.1016/j.jns.2014.04.032
    • (2014) J Neurol Sci , vol.342 , pp. 93-100
    • Chen, X.1    Zhao, Z.2    Chai, Y.3    Luo, L.4    Jiang, R.5    Zhang, J.6
  • 26
  • 27
    • 0030580435 scopus 로고    scopus 로고
    • Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits
    • COI: 1:CAS:528:DyaK28Xms1CjsLY%3D, PID: 895593
    • Colicos MA, Dixon CE, Dash PK (1996) Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits. Brain Res 739:111–119
    • (1996) Brain Res , vol.739 , pp. 111-119
    • Colicos, M.A.1    Dixon, C.E.2    Dash, P.K.3
  • 30
    • 84870408539 scopus 로고    scopus 로고
    • The blood–brain barrier in health and disease
    • COI: 1:CAS:528:DC%2BC3sXnt1Wj, PID: 2328078
    • Daneman R (2012) The blood–brain barrier in health and disease. Ann Neurol 72:648–672. doi:10.1002/ana.23648
    • (2012) Ann Neurol , vol.72 , pp. 648-672
    • Daneman, R.1
  • 31
    • 78649487239 scopus 로고    scopus 로고
    • Pericytes are required for blood–brain barrier integrity during embryogenesis
    • COI: 1:CAS:528:DC%2BC3cXht1yjs7bI, PID: 2094462
    • Daneman R, Zhou L, Kebede AA, Barres BA (2010) Pericytes are required for blood–brain barrier integrity during embryogenesis. Nature 468:562–566. doi:10.1038/nature09513
    • (2010) Nature , vol.468 , pp. 562-566
    • Daneman, R.1    Zhou, L.2    Kebede, A.A.3    Barres, B.A.4
  • 32
    • 84867288282 scopus 로고    scopus 로고
    • New perspectives on central and peripheral immune responses to acute traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3sXitlSmsLw%3D, PID: 2306191
    • Das M, Mohapatra S, Mohapatra SS (2012) New perspectives on central and peripheral immune responses to acute traumatic brain injury. J Neuroinflammation 9:236. doi:10.1186/1742-2094-9-236
    • (2012) J Neuroinflammation , vol.9 , pp. 236
    • Das, M.1    Mohapatra, S.2    Mohapatra, S.S.3
  • 33
    • 0033754531 scopus 로고    scopus 로고
    • The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability
    • Dejana E, Lampugnani MG, Martinez-Estrada O, Bazzoni G (2004) The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability. Int J Dev Biol 44:743–748
    • (2004) Int J Dev Biol , vol.44 , pp. 743-748
    • Dejana, E.1    Lampugnani, M.G.2    Martinez-Estrada, O.3    Bazzoni, G.4
  • 34
    • 84879569229 scopus 로고    scopus 로고
    • Increased intracranial pressure and brain edema
    • COI: 1:STN:280:DC%2BC3svnt1OgtQ%3D%3
    • Dietrich W, Erbguth F (2013) Increased intracranial pressure and brain edema. Med Klin Intensivmed Notfallmed 108:157–169
    • (2013) Med Klin Intensivmed Notfallmed , vol.108 , pp. 157-169
    • Dietrich, W.1    Erbguth, F.2
  • 35
    • 84896699377 scopus 로고    scopus 로고
    • Inhibition of phosphatase and tensin homolog deleted on chromosome 10 decreases rat cortical neuron injury and blood–brain barrier permeability, and improves neurological functional recovery in traumatic brain injury model
    • PID: 2431222
    • Ding J, Guo J, Yuan Q, Yuan F, Chen H, Tian H (2013) Inhibition of phosphatase and tensin homolog deleted on chromosome 10 decreases rat cortical neuron injury and blood–brain barrier permeability, and improves neurological functional recovery in traumatic brain injury model. PLoS One 8:e80429. doi:10.1371/journal.pone.0080429
    • (2013) PLoS One , vol.8 , pp. 80429
    • Ding, J.1    Guo, J.2    Yuan, Q.3    Yuan, F.4    Chen, H.5    Tian, H.6
  • 36
    • 0026062640 scopus 로고
    • A controlled cortical impact model of traumatic brain injury in the rat
    • COI: 1:STN:280:DyaK387lslKnuw%3D%3D, PID: 178774
    • Dixon CE, Clifton GL, Lighthall JW, Yaghmai AA, Hayes RL (1991) A controlled cortical impact model of traumatic brain injury in the rat. J Neurosci Methods 39:253–262
    • (1991) J Neurosci Methods , vol.39 , pp. 253-262
    • Dixon, C.E.1    Clifton, G.L.2    Lighthall, J.W.3    Yaghmai, A.A.4    Hayes, R.L.5
  • 37
    • 0033944791 scopus 로고    scopus 로고
    • Pericyte migration from the vascular wall in response to traumatic brain injury
    • COI: 1:STN:280:DC%2BD3cvpslaqsQ%3D%3D, PID: 1087351
    • Dore-Duffy P, Owen C, Balabanov R, Murphy S, Beaumont T, Rafols JA (2000) Pericyte migration from the vascular wall in response to traumatic brain injury. Microvasc Res 60:55–69
    • (2000) Microvasc Res , vol.60 , pp. 55-69
    • Dore-Duffy, P.1    Owen, C.2    Balabanov, R.3    Murphy, S.4    Beaumont, T.5    Rafols, J.A.6
  • 38
    • 84861184294 scopus 로고    scopus 로고
    • Barriers in the developing brain and Neurotoxicology
    • COI: 1:CAS:528:DC%2BC38XntlOhtrg%3D, PID: 2219870
    • Ek CJ, Dziegielewska KM, Habgood MD, Saunders NR (2012) Barriers in the developing brain and Neurotoxicology. Neurotoxicology 33:586–604. doi:10.1016/j.neuro.2011.12.009
    • (2012) Neurotoxicology , vol.33 , pp. 586-604
    • Ek, C.J.1    Dziegielewska, K.M.2    Habgood, M.D.3    Saunders, N.R.4
  • 39
    • 73449115641 scopus 로고    scopus 로고
    • The blood–brain and the blood-cerebrospinal fluid barriers: function and dysfunction
    • PID: 1977972
    • Engelhardt B, Sorokin L (2009) The blood–brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Semin Immunopathol 31:497–511. doi:10.1007/s00281-009-0177-0
    • (2009) Semin Immunopathol , vol.31 , pp. 497-511
    • Engelhardt, B.1    Sorokin, L.2
  • 40
    • 84898621882 scopus 로고    scopus 로고
    • Expression of S100A6 in rat hippocampus after traumatic brain injury due to lateral headacceleration
    • COI: 1:CAS:528:DC%2BC2cXhtlWltbbI, PID: 2473980
    • Fang B, Liang M, Yang G, Ye Y, Xu H, He X, Huang JH (2014) Expression of S100A6 in rat hippocampus after traumatic brain injury due to lateral headacceleration. Int J Mol Sci 15(4):6378–6390. doi:10.3390/ijms15046378
    • (2014) Int J Mol Sci , vol.15 , Issue.4 , pp. 6378-6390
    • Fang, B.1    Liang, M.2    Yang, G.3    Ye, Y.4    Xu, H.5    He, X.6    Huang, J.H.7
  • 41
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • COI: 1:CAS:528:DyaK1cXntlKqurw%3D, PID: 979268
    • Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM (1998) The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273:29745–29753
    • (1998) J Biol Chem , vol.273 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 43
    • 0036835885 scopus 로고    scopus 로고
    • Traumatic brain injury
    • COI: 1:STN:280:DC%2BD38nos1ajtw%3D%3D, PID: 1245019
    • Finnie JW, Blumbergs PC (2002) Traumatic brain injury. Vet Pathol 39:679–689
    • (2002) Vet Pathol , vol.39 , pp. 679-689
    • Finnie, J.W.1    Blumbergs, P.C.2
  • 45
    • 84871554032 scopus 로고    scopus 로고
    • Aquaporin 4: a player in cerebral edema and neuroinflammation
    • COI: 1:CAS:528:DC%2BC3sXitlSms7o%3D, PID: 2327050
    • Fukuda AM, Badaut J (2012) Aquaporin 4: a player in cerebral edema and neuroinflammation. J Neuroinflammation 9:279
    • (2012) J Neuroinflammation , vol.9 , pp. 279
    • Fukuda, A.M.1    Badaut, J.2
  • 46
    • 84871689084 scopus 로고    scopus 로고
    • Association between reduced expression of hippocampal glucocorticoid receptors and cognitive dysfunction in a rat model of traumatic brain injury due to lateral head acceleration
    • COI: 1:CAS:528:DC%2BC38XhvVektbzO, PID: 2320072
    • Gao W, Xu H, Liang M, Huang JH, He X (2013) Association between reduced expression of hippocampal glucocorticoid receptors and cognitive dysfunction in a rat model of traumatic brain injury due to lateral head acceleration. Neurosci Lett 533:50–54. doi:10.1016/j.neulet.2012.11.020
    • (2013) Neurosci Lett , vol.533 , pp. 50-54
    • Gao, W.1    Xu, H.2    Liang, M.3    Huang, J.H.4    He, X.5
  • 49
    • 78651063705 scopus 로고    scopus 로고
    • Leuckocyte-endothelial cell crosstalk at the blood–brain barrier: a prerequisite for successful immune cell entry to the brain
    • COI: 1:CAS:528:DC%2BC3MXhvV2rtL4%3D, PID: 2094647
    • Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B (2011) Leuckocyte-endothelial cell crosstalk at the blood–brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathol Appl Neurobiol 37:24–39. doi:10.1111/j.1365-2990.2010.01140.x
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 24-39
    • Greenwood, J.1    Heasman, S.J.2    Alvarez, J.I.3    Prat, A.4    Lyck, R.5    Engelhardt, B.6
  • 50
    • 66849128097 scopus 로고    scopus 로고
    • Pathophysiology of traumatic brain injury
    • PID: 1930637
    • Greve MW, Zink BJ (2009) Pathophysiology of traumatic brain injury. Mt Sinai J Med 76:97–104. doi:10.1002/msj.20104
    • (2009) Mt Sinai J Med , vol.76 , pp. 97-104
    • Greve, M.W.1    Zink, B.J.2
  • 51
    • 84878220173 scopus 로고    scopus 로고
    • Relationship between central and peripheral fatty acids in humans
    • COI: 1:CAS:528:DC%2BC3sXhtVanurbF, PID: 2371064
    • Guest J, Garg M, Bilgin A, Grant R (2013) Relationship between central and peripheral fatty acids in humans. Lipids Health Dis 12:79. doi:10.1186/1476-511X-12-79
    • (2013) Lipids Health Dis , vol.12 , pp. 79
    • Guest, J.1    Garg, M.2    Bilgin, A.3    Grant, R.4
  • 52
    • 84884677371 scopus 로고    scopus 로고
    • Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3sXhs1WiurzO, PID: 2403641
    • Haber M, Abdel Baki SG, Grin’kina NM, Irizarry R, Ershova A, Orsi S, Grill RJ, Dash P, Bergold PJ (2013) Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury. Exp Neurol 249:169–177. doi:10.1016/j.expneurol.2013.09.002
    • (2013) Exp Neurol , vol.249 , pp. 169-177
    • Haber, M.1    Abdel Baki, S.G.2    Grin’kina, N.M.3    Irizarry, R.4    Ershova, A.5    Orsi, S.6    Grill, R.J.7    Dash, P.8    Bergold, P.J.9
  • 53
    • 33846216899 scopus 로고    scopus 로고
    • Changes in blood–brain barrier permeability to large and small molecules following traumatic brain injury in mice
    • COI: 1:STN:280:DC%2BD2s7is1CltA%3D%3D, PID: 1724128
    • Habgood MD, Bye N, Dziegielewska KM, Ek CJ, Lane MA, Potter A, Morganti-Kossmann C, Saunders NR (2007) Changes in blood–brain barrier permeability to large and small molecules following traumatic brain injury in mice. Eur J Neurosci 25:231–238
    • (2007) Eur J Neurosci , vol.25 , pp. 231-238
    • Habgood, M.D.1    Bye, N.2    Dziegielewska, K.M.3    Ek, C.J.4    Lane, M.A.5    Potter, A.6    Morganti-Kossmann, C.7    Saunders, N.R.8
  • 54
    • 77953856953 scopus 로고    scopus 로고
    • Effect of COX-2 inhibitor meloxicam against traumatic brain injury-induced biochemical, histopathological changes and blood–brain barrier permeability
    • COI: 1:CAS:528:DC%2BC3cXht12ms7fP, PID: 1966023
    • Hakan T, Toklu HZ, Biber N, Ozevren H, Solakoglu S, Demirturk P, Aker FV (2010) Effect of COX-2 inhibitor meloxicam against traumatic brain injury-induced biochemical, histopathological changes and blood–brain barrier permeability. Neurol Res 32:629–635. doi:10.1179/016164109X12464612122731
    • (2010) Neurol Res , vol.32 , pp. 629-635
    • Hakan, T.1    Toklu, H.Z.2    Biber, N.3    Ozevren, H.4    Solakoglu, S.5    Demirturk, P.6    Aker, F.V.7
  • 55
    • 40949158910 scopus 로고    scopus 로고
    • Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods
    • PID: 1835283
    • Hall ED, Bryant YD, Cho W, Sullivan PG (2008) Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods. J Neurotrauma 25:235–247. doi:10.1089/neu.2007.0383
    • (2008) J Neurotrauma , vol.25 , pp. 235-247
    • Hall, E.D.1    Bryant, Y.D.2    Cho, W.3    Sullivan, P.G.4
  • 56
    • 22244448718 scopus 로고    scopus 로고
    • Regulation of protein function by glycosaminoglycans—as exemplified by chemokines
    • COI: 1:CAS:528:DC%2BD2MXpsVens7c%3D, PID: 1595289
    • Handel TM, Johnson Z, Crown SE, Lau EK, Proudfoot AE (2005) Regulation of protein function by glycosaminoglycans—as exemplified by chemokines. Annu Rev Biochem 74:385–410
    • (2005) Annu Rev Biochem , vol.74 , pp. 385-410
    • Handel, T.M.1    Johnson, Z.2    Crown, S.E.3    Lau, E.K.4    Proudfoot, A.E.5
  • 57
    • 34447558578 scopus 로고    scopus 로고
    • Traumatic brain injury: intensive care management
    • COI: 1:STN:280:DC%2BD2szlslentg%3D%3D, PID: 1755634
    • Helmy A, Vizcaychipi M, Gupta AK (2007) Traumatic brain injury: intensive care management. Br J Anaesth 99:32–42
    • (2007) Br J Anaesth , vol.99 , pp. 32-42
    • Helmy, A.1    Vizcaychipi, M.2    Gupta, A.K.3
  • 58
    • 0032908722 scopus 로고    scopus 로고
    • Leukocyte traffic in the central nervous system: the participants and their roles
    • COI: 1:STN:280:DyaK1M3mtlCisw%3D%3D, PID: 1032949
    • Hickey WF (1999) Leukocyte traffic in the central nervous system: the participants and their roles. Semin Immunol 11:125–137
    • (1999) Semin Immunol , vol.11 , pp. 125-137
    • Hickey, W.F.1
  • 59
    • 53249130558 scopus 로고    scopus 로고
    • Administration of haloperidol and risperidone after neurobehavioral testing hinders the recovery of traumatic brain injury-induced deficits
    • COI: 1:CAS:528:DC%2BD1cXht1entLbL, PID: 1880137
    • Hoffman AN, Cheng JP, Zafonte RD, Kline AE (2008) Administration of haloperidol and risperidone after neurobehavioral testing hinders the recovery of traumatic brain injury-induced deficits. Life Sci 83:602–607. doi:10.1016/j.lfs.2008.08.007
    • (2008) Life Sci , vol.83 , pp. 602-607
    • Hoffman, A.N.1    Cheng, J.P.2    Zafonte, R.D.3    Kline, A.E.4
  • 60
    • 50349135527 scopus 로고
    • Mechanics of head injuries
    • Holbourn AH (1943) Mechanics of head injuries. Lancet 2:438–441
    • (1943) Lancet , vol.2 , pp. 438-441
    • Holbourn, A.H.1
  • 61
    • 64149114105 scopus 로고    scopus 로고
    • Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood–brain barrier damage
    • COI: 1:CAS:528:DC%2BD1MXlsFykt7o%3D, PID: 1918744
    • Hooper C, Pinteaux-Jones F, Fry VA, Sevastou IG, Baker D, Heales SJ, Pocock JM (2009) Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood–brain barrier damage. J Neurochem 109:694–705
    • (2009) J Neurochem , vol.109 , pp. 694-705
    • Hooper, C.1    Pinteaux-Jones, F.2    Fry, V.A.3    Sevastou, I.G.4    Baker, D.5    Heales, S.J.6    Pocock, J.M.7
  • 62
    • 84900336732 scopus 로고    scopus 로고
    • Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood–brain barrier model
    • PID: 2437235
    • Hue CD, Cao S, Dale Bass CR, Meaney DF, Morrison B 3rd (2014) Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood–brain barrier model. J Neurotrauma 31:951–960. doi:10.1089/neu.2013.3149
    • (2014) J Neurotrauma , vol.31 , pp. 951-960
    • Hue, C.D.1    Cao, S.2    Dale Bass, C.R.3    Meaney, D.F.4    Morrison, B.5
  • 64
    • 33846415442 scopus 로고    scopus 로고
    • Acute treatment with the 5-HT(1A) receptor agonist 8-OH-DPAT and chronic environmental enrichment confer neurobehavioral benefit after experimental brain trauma
    • COI: 1:CAS:528:DC%2BD2sXhtVCiu78%3D, PID: 1716660
    • Kline AE, Wagner AK, Westergom BP, Malena RR, Zafonte RD, Olsen AS, Sozda CN, Luthra P, Panda M, Cheng JP, Aslam HA (2007) Acute treatment with the 5-HT(1A) receptor agonist 8-OH-DPAT and chronic environmental enrichment confer neurobehavioral benefit after experimental brain trauma. Behav Brain Res 177:186–194
    • (2007) Behav Brain Res , vol.177 , pp. 186-194
    • Kline, A.E.1    Wagner, A.K.2    Westergom, B.P.3    Malena, R.R.4    Zafonte, R.D.5    Olsen, A.S.6    Sozda, C.N.7    Luthra, P.8    Panda, M.9    Cheng, J.P.10    Aslam, H.A.11
  • 65
    • 56249133828 scopus 로고    scopus 로고
    • Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury
    • COI: 1:CAS:528:DC%2BD1cXhsVWnur3N, PID: 1898389
    • Kline AE, Hoffman AN, Cheng JP, Zafonte RD, Massucci JL (2008) Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury. Neurosci Lett 448:263–267. doi:10.1016/j.neulet.2008.10.076
    • (2008) Neurosci Lett , vol.448 , pp. 263-267
    • Kline, A.E.1    Hoffman, A.N.2    Cheng, J.P.3    Zafonte, R.D.4    Massucci, J.L.5
  • 66
    • 84884218376 scopus 로고    scopus 로고
    • The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas
    • PID: 2402356
    • Könnecke H, Bechmann I (2013) The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas. Clin Dev Immunol 2013:914104
    • (2013) Clin Dev Immunol , vol.2013 , pp. 914104
    • Könnecke, H.1    Bechmann, I.2
  • 67
    • 27844518332 scopus 로고    scopus 로고
    • The critical component to establish in vitro BBB model: Pericyte
    • COI: 1:CAS:528:DC%2BD2MXht1GisbbL, PID: 1619909
    • Lai CH, Kuo KH (2005) The critical component to establish in vitro BBB model: Pericyte. Brain Res Brain Res Rev 50:258–265
    • (2005) Brain Res Brain Res Rev , vol.50 , pp. 258-265
    • Lai, C.H.1    Kuo, K.H.2
  • 68
    • 84862793270 scopus 로고    scopus 로고
    • Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice
    • PID: 2220154
    • Lee P, Kim J, Williams R, Sandhir R, Gregory E, Brooks WM, Berman NE (2011) Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice. Exp Neurol 234:50–61. doi:10.1016/j.expneurol.2011.12.016
    • (2011) Exp Neurol , vol.234 , pp. 50-61
    • Lee, P.1    Kim, J.2    Williams, R.3    Sandhir, R.4    Gregory, E.5    Brooks, W.M.6    Berman, N.E.7
  • 69
    • 84880799341 scopus 로고    scopus 로고
    • Oxidative burst of circulating neutrophils following traumatic brain injury in human
    • COI: 1:CAS:528:DC%2BC3sXht1ertrfJ, PID: 2389438
    • Liao Y, Liu P, Guo F, Zhang ZY, Zhang Z (2013) Oxidative burst of circulating neutrophils following traumatic brain injury in human. PLoS One 8:e68963. doi:10.1371/journal.pone.0068963
    • (2013) PLoS One , vol.8 , pp. 68963
    • Liao, Y.1    Liu, P.2    Guo, F.3    Zhang, Z.Y.4    Zhang, Z.5
  • 70
    • 80051730491 scopus 로고    scopus 로고
    • Fluids and barriers of the CNS: a historical viewpoint
    • Liddelow SA (2011) Fluids and barriers of the CNS: a historical viewpoint. Fluids Barrier CNS 8:2. doi:10.1186/2045-8118-8-2
    • (2011) Fluids Barrier CNS , vol.8 , pp. 2
    • Liddelow, S.A.1
  • 71
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • COI: 1:CAS:528:DyaK2sXksFCksb0%3D, PID: 921185
    • Lindahl P, Johansson BR, Leeven P, Betsholtz C (1997) Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277:242–245
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Leeven, P.3    Betsholtz, C.4
  • 73
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • COI: 1:CAS:528:DC%2BD28XisVCnsQ%3D%3D, PID: 1640210
    • Lucas SM, Rothwell NJ, Gibson RM (2006) The role of inflammation in CNS injury and disease. Br J Pharmacol 147:S232–S240
    • (2006) Br J Pharmacol , vol.147 , pp. 232-240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 75
    • 84874805543 scopus 로고    scopus 로고
    • Coagulopathy after traumatic brain injury: incidence, pathology, and treatment options
    • PID: 2330197
    • Maegele M (2013) Coagulopathy after traumatic brain injury: incidence, pathology, and treatment options. Transfusion 53:28S–37S. doi:10.1111/trf.12033
    • (2013) Transfusion , vol.53 , pp. 28-37
    • Maegele, M.1
  • 77
    • 0038617335 scopus 로고    scopus 로고
    • Functional analysis of tight junctions
    • COI: 1:CAS:528:DC%2BD3sXkt1Oqurs%3D, PID: 1279813
    • Matter K, Balda MS (2003) Functional analysis of tight junctions. Methods 30:228–234
    • (2003) Methods , vol.30 , pp. 228-234
    • Matter, K.1    Balda, M.S.2
  • 78
    • 0035321099 scopus 로고    scopus 로고
    • Regulation of blood–brain barrier permeability
    • COI: 1:CAS:528:DC%2BD3MXktFylsL8%3D, PID: 1137979
    • Mayhan WG (2001) Regulation of blood–brain barrier permeability. Microcirculation 8:89–104
    • (2001) Microcirculation , vol.8 , pp. 89-104
    • Mayhan, W.G.1
  • 79
    • 0035195569 scopus 로고    scopus 로고
    • Diffuse axonal injury
    • COI: 1:STN:280:DC%2BD38%2FktVyjtA%3D%3D, PID: 1176583
    • Meaney DF, Margulies SS, Smith DH (2001) Diffuse axonal injury. J Neurosurg 95:1108–1110
    • (2001) J Neurosurg , vol.95 , pp. 1108-1110
    • Meaney, D.F.1    Margulies, S.S.2    Smith, D.H.3
  • 80
    • 84862855314 scopus 로고    scopus 로고
    • Blood–brain barrier and retroviral infections
    • PID: 2246063
    • Miller F, Afonso PV, Gessain A, Ceccaldi PE (2012) Blood–brain barrier and retroviral infections. Virulence 3:222–229. doi:10.4161/viru.19697
    • (2012) Virulence , vol.3 , pp. 222-229
    • Miller, F.1    Afonso, P.V.2    Gessain, A.3    Ceccaldi, P.E.4
  • 81
    • 0344961161 scopus 로고    scopus 로고
    • Blood–brain barrier disruption in multiple sclerosis
    • COI: 1:CAS:528:DC%2BD3sXhtVSqtr3M, PID: 1466446
    • Minagar A, Alexander JS (2003) Blood–brain barrier disruption in multiple sclerosis. Mult Scler 9:540–549
    • (2003) Mult Scler , vol.9 , pp. 540-549
    • Minagar, A.1    Alexander, J.S.2
  • 82
    • 79960489223 scopus 로고    scopus 로고
    • In vitro models of traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3MXhtFCit7zE, PID: 2152916
    • Morrison B 3rd, Elkin BS, Dollé JP, Yarmush ML (2011) In vitro models of traumatic brain injury. Annu Rev Biomed Eng 13:91–126. doi:10.1146/annurev-bioeng-071910-124706
    • (2011) Annu Rev Biomed Eng , vol.13 , pp. 91-126
    • Morrison, B.1    Elkin, B.S.2    Dollé, J.P.3    Yarmush, M.L.4
  • 83
    • 84878174793 scopus 로고    scopus 로고
    • Mechanisms and consequences of acquired brain injury during development
    • COI: 1:CAS:528:DC%2BC3sXovVCltrw%3D, PID: 2249478
    • Morrison G, Fraser DD, Cepinskas G (2013) Mechanisms and consequences of acquired brain injury during development. Pathophysiology 20:49–57. doi:10.1016/j.pathophys.2012.02.006
    • (2013) Pathophysiology , vol.20 , pp. 49-57
    • Morrison, G.1    Fraser, D.D.2    Cepinskas, G.3
  • 84
    • 79957755796 scopus 로고    scopus 로고
    • Morphology and properties of brain endothelial cells
    • COI: 1:CAS:528:DC%2BC3cXhs1WrsL3N, PID: 2108236
    • Nag S (2011) Morphology and properties of brain endothelial cells. Methods Mol Biol 686:3–47. doi:10.1007/978-1-60761-938-3_1
    • (2011) Methods Mol Biol , vol.686 , pp. 3-47
    • Nag, S.1
  • 85
    • 78651106773 scopus 로고    scopus 로고
    • Review: molecular pathogenesis of blood–brain barrier breakdown in acute brain injury
    • COI: 1:CAS:528:DC%2BC3MXhvV2rt7Y%3D, PID: 2094624
    • Nag S, Kapadia A, Stewart DJ (2011) Review: molecular pathogenesis of blood–brain barrier breakdown in acute brain injury. Neuropathol Appl Neurobiol 37:3–23. doi:10.1111/j.1365-2990.2010.01138.x
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 3-23
    • Nag, S.1    Kapadia, A.2    Stewart, D.J.3
  • 86
    • 60949110463 scopus 로고    scopus 로고
    • A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
    • COI: 1:CAS:528:DC%2BD1MXivVGqsbw%3D, PID: 1911186
    • Nakagawa S, Deli MA, Kawaguchi H, Shimizudani T, Shimono T, Kittel A, Tanaka K, Niwa M (2009) A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. Neurochem Int 54:253–263. doi:10.1016/j.neuint.2008.12.002
    • (2009) Neurochem Int , vol.54 , pp. 253-263
    • Nakagawa, S.1    Deli, M.A.2    Kawaguchi, H.3    Shimizudani, T.4    Shimono, T.5    Kittel, A.6    Tanaka, K.7    Niwa, M.8
  • 88
    • 1442281879 scopus 로고    scopus 로고
    • Blood–brain barrier disruption following traumatic brain injury: roles of tight junction proteins
    • COI: 1:STN:280:DC%2BD2c%2FnvFKhtw%3D%3
    • Ng I, Yap E, Tan WL, Kong NY (2003) Blood–brain barrier disruption following traumatic brain injury: roles of tight junction proteins. Ann Acad Med Singa 32:S63–S66
    • (2003) Ann Acad Med Singa , vol.32 , pp. 63-66
    • Ng, I.1    Yap, E.2    Tan, W.L.3    Kong, N.Y.4
  • 89
    • 84889872057 scopus 로고    scopus 로고
    • Development, maintenance and disruption of the blood–brain barrier
    • COI: 1:CAS:528:DC%2BC3sXhvVyisLbJ, PID: 2430966
    • Obermeier B, Daneman R, Ransohoff RM (2013) Development, maintenance and disruption of the blood–brain barrier. Nat Med 19:1584–1596. doi:10.1038/nm.3407
    • (2013) Nat Med , vol.19 , pp. 1584-1596
    • Obermeier, B.1    Daneman, R.2    Ransohoff, R.M.3
  • 90
    • 79953661325 scopus 로고    scopus 로고
    • Animal models of traumatic brain injury: a critical evaluation
    • PID: 2125686
    • O’Connor WT, Smyth A, Gilchrist MD (2011) Animal models of traumatic brain injury: a critical evaluation. Pharmacol Ther 130:106–113. doi:10.1016/j.pharmthera.2011.01.001
    • (2011) Pharmacol Ther , vol.130 , pp. 106-113
    • O’Connor, W.T.1    Smyth, A.2    Gilchrist, M.D.3
  • 91
    • 0017757318 scopus 로고
    • The blood–brain barrier
    • COI: 1:CAS:528:DyaE1cXkslylsA%3D%3D, PID: 33831
    • Oldendorf WH (1977) The blood–brain barrier. Exp Eye Res 25:177–190
    • (1977) Exp Eye Res , vol.25 , pp. 177-190
    • Oldendorf, W.H.1
  • 92
    • 39849102702 scopus 로고    scopus 로고
    • Structural organization of the tight junctions
    • COI: 1:CAS:528:DC%2BD1cXjtVSqt7o%3D, PID: 1794518
    • Paris L, Tonutti L, Vannini C, Bazzoni G (2008) Structural organization of the tight junctions. Biochim Biophys Acta 1778:646–659
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 646-659
    • Paris, L.1    Tonutti, L.2    Vannini, C.3    Bazzoni, G.4
  • 93
    • 84856798292 scopus 로고    scopus 로고
    • Pathophysiology and treatment of traumatic brain edema
    • Patro A, Mohanty S (2009) Pathophysiology and treatment of traumatic brain edema. Indian J Neurotrauma 6:11–16
    • (2009) Indian J Neurotrauma , vol.6 , pp. 11-16
    • Patro, A.1    Mohanty, S.2
  • 94
    • 84865745668 scopus 로고    scopus 로고
    • Emergency department visits for traumatic brain injury in older adults in the United States: 2006–08
    • PID: 2292805
    • Pearson WS, Sugerman DE, McGuire LC, Coronado VG (2012) Emergency department visits for traumatic brain injury in older adults in the United States: 2006–08. West J Emerg Med 13:289–293. doi:10.5811/westjem.2012.3.11559
    • (2012) West J Emerg Med , vol.13 , pp. 289-293
    • Pearson, W.S.1    Sugerman, D.E.2    McGuire, L.C.3    Coronado, V.G.4
  • 95
    • 33747368249 scopus 로고    scopus 로고
    • Blood–brain barrier: structural components and function under physiologic and pathologic conditions
    • Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD (2006) Blood–brain barrier: structural components and function under physiologic and pathologic conditions. J Neuroimmune Pharm 1:223–236
    • (2006) J Neuroimmune Pharm , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 96
    • 83355169561 scopus 로고    scopus 로고
    • A neurovascular perspective for long-term changes after brain trauma
    • COI: 1:STN:280:DC%2BC2c3kvFKmtg%3D%3D, PID: 2235062
    • Pop V, Badaut J (2011) A neurovascular perspective for long-term changes after brain trauma. Transl Stroke Res 2:533–545
    • (2011) Transl Stroke Res , vol.2 , pp. 533-545
    • Pop, V.1    Badaut, J.2
  • 97
    • 80055116339 scopus 로고    scopus 로고
    • Dynamic mechanical response of brain tissue in indentation in vivo, in situ and in vitro
    • PID: 2174206
    • Prevost TP, Jin G, de Moya MA, Alam HB, Suresh S, Socrate S (2011) Dynamic mechanical response of brain tissue in indentation in vivo, in situ and in vitro. Acta Biomater 7:4090–4101. doi:10.1016/j.actbio.2011.06.032
    • (2011) Acta Biomater , vol.7 , pp. 4090-4101
    • Prevost, T.P.1    Jin, G.2    de Moya, M.A.3    Alam, H.B.4    Suresh, S.5    Socrate, S.6
  • 98
    • 67650153191 scopus 로고    scopus 로고
    • Involvement of ROS in BBB dysfunction
    • COI: 1:CAS:528:DC%2BD1MXjvFOnt70%3D, PID: 1924124
    • Pun PB, Lu J, Moochhala S (2009) Involvement of ROS in BBB dysfunction. Free Radic Res 43:348–364
    • (2009) Free Radic Res , vol.43 , pp. 348-364
    • Pun, P.B.1    Lu, J.2    Moochhala, S.3
  • 99
    • 0017163209 scopus 로고
    • Opening of the blood–brain barrier by acute hypertension
    • COI: 1:STN:280:DyaE283lslGmug%3D%3D, PID: 95491
    • Rapoport SI (1976) Opening of the blood–brain barrier by acute hypertension. Exp Neurol 52:467–479
    • (1976) Exp Neurol , vol.52 , pp. 467-479
    • Rapoport, S.I.1
  • 100
    • 0040782187 scopus 로고    scopus 로고
    • The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin–Darby canine kidney I cells—evidence for a role of b- catenin /Tcf/Lef signaling
    • COI: 1:CAS:528:DC%2BD3cXitlCru7o%3D, PID: 1073409
    • Reichert M, Muller T, Hunziker W (2000) The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin–Darby canine kidney I cells—evidence for a role of b- catenin /Tcf/Lef signaling. J Biol Chem 275:9492–9500
    • (2000) J Biol Chem , vol.275 , pp. 9492-9500
    • Reichert, M.1    Muller, T.2    Hunziker, W.3
  • 101
    • 84878580322 scopus 로고    scopus 로고
    • ‘Hit & Run’ model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation
    • COI: 1:CAS:528:DC%2BC3sXptVWqsbg%3D, PID: 2344317
    • Ren Z, Iliff JJ, Yang L, Yang J, Chen X, Chen MJ, Giese RN, Wang B, Shi X, Nedergaard M (2013) ‘Hit & Run’ model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. J Cereb Blood Flow Metab 33:834–845
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 834-845
    • Ren, Z.1    Iliff, J.J.2    Yang, L.3    Yang, J.4    Chen, X.5    Chen, M.J.6    Giese, R.N.7    Wang, B.8    Shi, X.9    Nedergaard, M.10
  • 102
    • 0029560419 scopus 로고
    • Cerebral prefusion pressure: management protocol and clinical results
    • COI: 1:STN:280:DyaK28%2Fos1ymug%3D%3D, PID: 749063
    • Rosner MJ, Rosner MD (1995) Cerebral prefusion pressure: management protocol and clinical results. J Neurosurg 83:949–962
    • (1995) J Neurosurg , vol.83 , pp. 949-962
    • Rosner, M.J.1    Rosner, M.D.2
  • 103
    • 48249108682 scopus 로고    scopus 로고
    • Classification of traumatic brain injury for targeted therapies
    • PID: 1862725
    • Saatman KE, Duhaime AC, Bullock R, Maas AI, Valadka A, Manley GT, Workshop Scientific Team and Advisory Panel Members (2008) Classification of traumatic brain injury for targeted therapies. J Neurotrauma 25:719–738. doi:10.1089/neu.2008.0586
    • (2008) J Neurotrauma , vol.25 , pp. 719-738
    • Saatman, K.E.1    Duhaime, A.C.2    Bullock, R.3    Maas, A.I.4    Valadka, A.5    Manley, G.T.6
  • 104
    • 67249085206 scopus 로고    scopus 로고
    • Tight junctions: molecular structure meets function
    • COI: 1:CAS:528:DC%2BD1MXot1Ghtb0%3D, PID: 1953828
    • Schulzke JD, Fromm M (2009) Tight junctions: molecular structure meets function. Ann N Y Acad Sci 1165:1–6. doi:10.1111/j.1749-6632.2009.04925.x
    • (2009) Ann N Y Acad Sci , vol.1165 , pp. 1-6
    • Schulzke, J.D.1    Fromm, M.2
  • 105
    • 84904644453 scopus 로고    scopus 로고
    • Incidence, prevalence, and occurrence rate of infection among adults hospitalized after traumatic brain injury: study protocol for a systematic review and meta-analysis
    • PID: 2397151
    • Scott BN, Roberts DJ, Robertson HL, Kramer AH, Laupland KB, Ousman SS, Kubes P, Zygun DA (2013) Incidence, prevalence, and occurrence rate of infection among adults hospitalized after traumatic brain injury: study protocol for a systematic review and meta-analysis. Syst Rev 2:68
    • (2013) Syst Rev , vol.2 , pp. 68
    • Scott, B.N.1    Roberts, D.J.2    Robertson, H.L.3    Kramer, A.H.4    Laupland, K.B.5    Ousman, S.S.6    Kubes, P.7    Zygun, D.A.8
  • 106
    • 0027213179 scopus 로고
    • Blood–brain barrier permeability, cerebral edema, and neurologic function after closed head injury in rats
    • COI: 1:STN:280:DyaK3szgsVKquw%3D%3D, PID: 831772
    • Shapira Y, Setton D, Artru AA, Shohami E (1993) Blood–brain barrier permeability, cerebral edema, and neurologic function after closed head injury in rats. Anesth Analg 77:141–148
    • (1993) Anesth Analg , vol.77 , pp. 141-148
    • Shapira, Y.1    Setton, D.2    Artru, A.A.3    Shohami, E.4
  • 107
    • 80054758194 scopus 로고    scopus 로고
    • Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood–brain barrier permeability, and brain edema formation
    • PID: 2164481
    • Shear DA, Lu XC, Pedersen R, Wei G, Chen Z, Davis A, Yao C, Dave J, Tortella FC (2011) Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood–brain barrier permeability, and brain edema formation. J Neurotrauma 28:2185–2195. doi:10.1089/neu.2011.1916
    • (2011) J Neurotrauma , vol.28 , pp. 2185-2195
    • Shear, D.A.1    Lu, X.C.2    Pedersen, R.3    Wei, G.4    Chen, Z.5    Davis, A.6    Yao, C.7    Dave, J.8    Tortella, F.C.9
  • 108
    • 77954862661 scopus 로고    scopus 로고
    • A. Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3cXovFKgt7g%3D, PID: 2055194
    • Shlosberg D, Benifla M, Kaufer D, Friedman (2010) A. Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat Rev Neurol 6:393–403. doi:10.1038/nrneurol.2010.74
    • (2010) Nat Rev Neurol , vol.6 , pp. 393-403
    • Shlosberg, D.1    Benifla, M.2    Kaufer, D.3    Friedman4
  • 109
    • 9344248393 scopus 로고    scopus 로고
    • The neurobiology of glia in the context of water and ion homeostasis
    • COI: 1:CAS:528:DC%2BD2cXhtVSltbbK, PID: 1556140
    • Simard M, Nedergaard M (2004) The neurobiology of glia in the context of water and ion homeostasis. Neuroscience 129:877–896
    • (2004) Neuroscience , vol.129 , pp. 877-896
    • Simard, M.1    Nedergaard, M.2
  • 110
    • 84858742061 scopus 로고    scopus 로고
    • Traumatic brain injury: a risk factor for Alzheimer’s disease
    • PID: 2239091
    • Sivanandam TM, Thakur MK (2012) Traumatic brain injury: a risk factor for Alzheimer’s disease. Neurosci Biobehav Rev 36:1376–1381. doi:10.1016/j.neubiorev.2012.02.013
    • (2012) Neurosci Biobehav Rev , vol.36 , pp. 1376-1381
    • Sivanandam, T.M.1    Thakur, M.K.2
  • 111
    • 53249138093 scopus 로고    scopus 로고
    • Brain endothelial cell-cell junctions: how to “open” the blood brain barrier
    • COI: 1:CAS:528:DC%2BD1cXht1amurvE, PID: 1950671
    • Stamatovic SM, Keep RF, Andjelkovic AV (2008) Brain endothelial cell-cell junctions: how to “open” the blood brain barrier. Curr Neuropharmacol 6:179–192. doi:10.2174/157015908785777210
    • (2008) Curr Neuropharmacol , vol.6 , pp. 179-192
    • Stamatovic, S.M.1    Keep, R.F.2    Andjelkovic, A.V.3
  • 112
    • 84885058003 scopus 로고    scopus 로고
    • Immune responses at brain barriers and implications for brain development and neurological function in later life
    • PID: 2398666
    • Stolp HB, Liddelow SA, Sá-Pereira I, Dziegielewska KM, Saunders NR (2013) Immune responses at brain barriers and implications for brain development and neurological function in later life. Front Integr Neurosci 7:61. doi:10.3389/fnint.2013.00061
    • (2013) Front Integr Neurosci , vol.7 , pp. 61
    • Stolp, H.B.1    Liddelow, S.A.2    Sá-Pereira, I.3    Dziegielewska, K.M.4    Saunders, N.R.5
  • 113
    • 42049122347 scopus 로고    scopus 로고
    • The blood–brain barrier is continuously open for several weeks following transient focal cerebral ischemia
    • COI: 1:CAS:528:DC%2BD1cXkvVOktLY%3D, PID: 1836734
    • Strbian D, Durukan A, Pitkonen M, Marinkovic I, Tatlisumak E, Pedrono E, Abo-Ramadan U, Tatlisumak T (2008) The blood–brain barrier is continuously open for several weeks following transient focal cerebral ischemia. Neuroscience 153:175–181. doi:10.1016/j.neuroscience.2008.02.012
    • (2008) Neuroscience , vol.153 , pp. 175-181
    • Strbian, D.1    Durukan, A.2    Pitkonen, M.3    Marinkovic, I.4    Tatlisumak, E.5    Pedrono, E.6    Abo-Ramadan, U.7    Tatlisumak, T.8
  • 114
    • 2342419356 scopus 로고    scopus 로고
    • Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development
    • Taliquist MD, French WJ, Soriano P (2003) Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development. PLoS Biol 1:e52
    • (2003) PLoS Biol , vol.1 , pp. 52
    • Taliquist, M.D.1    French, W.J.2    Soriano, P.3
  • 115
    • 0027393388 scopus 로고
    • Immunolocalization of heat shock protein after fluid percussive brain injury and relationship to breakdown of the blood–brain barrier
    • COI: 1:CAS:528:DyaK3sXkt1Grtr8%3D, PID: 841700
    • Tanno H, Nockels RP, Pitts LH, Noble LJ (1993) Immunolocalization of heat shock protein after fluid percussive brain injury and relationship to breakdown of the blood–brain barrier. J Cereb Blood Flow Metab 13:116–124
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 116-124
    • Tanno, H.1    Nockels, R.P.2    Pitts, L.H.3    Noble, L.J.4
  • 116
    • 84870905282 scopus 로고    scopus 로고
    • Volatile anesthetics influence blood–brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3sXjt1U%3D, PID: 2325138
    • Thal SC, Luh C, Schaible EV, Timaru-Kast R, Hedrich J, Luhmann HJ, Engelhard K, Zehendner CM (2012) Volatile anesthetics influence blood–brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury. PLoS One 7:e50752. doi:10.1371/journal.pone.0050752
    • (2012) PLoS One , vol.7 , pp. 50752
    • Thal, S.C.1    Luh, C.2    Schaible, E.V.3    Timaru-Kast, R.4    Hedrich, J.5    Luhmann, H.J.6    Engelhard, K.7    Zehendner, C.M.8
  • 117
    • 0031976163 scopus 로고    scopus 로고
    • The epidemiology of sports-related traumatic brain injuries in the United States: recent developments
    • Thurman DJ, Branche CM, Sniezek JE (1998) The epidemiology of sports-related traumatic brain injuries in the United States: recent developments. J Head Trauma Rehabil 3:1–8
    • (1998) J Head Trauma Rehabil , vol.3 , pp. 1-8
    • Thurman, D.J.1    Branche, C.M.2    Sniezek, J.E.3
  • 120
    • 0038730794 scopus 로고    scopus 로고
    • Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist’s view
    • COI: 1:CAS:528:DC%2BD3sXkt1ensr8%3D, PID: 1279144
    • Vorbrodt AW, Dobrogowska DH (2003) Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist’s view. Brain Res Brain Res Rev 42:221–242
    • (2003) Brain Res Brain Res Rev , vol.42 , pp. 221-242
    • Vorbrodt, A.W.1    Dobrogowska, D.H.2
  • 121
    • 80053574871 scopus 로고    scopus 로고
    • Regulatory T cells in CNS injury: the simple, the complex and the confused
    • COI: 1:CAS:528:DC%2BC3MXht1ymtr7I, PID: 2174188
    • Walsh JT, Kipnis J (2011) Regulatory T cells in CNS injury: the simple, the complex and the confused. Trends Mol Med 17:541–547. doi:10.1016/j.molmed.2011.05.012
    • (2011) Trends Mol Med , vol.17 , pp. 541-547
    • Walsh, J.T.1    Kipnis, J.2
  • 122
    • 84885184477 scopus 로고    scopus 로고
    • Curcumin ameliorates the permeability of the blood–brain barrier during hypoxia by upregulating heme oxygenase-1 expression in brain microvascular endothelial cells
    • COI: 1:CAS:528:DC%2BC3sXhsV2nurnP, PID: 2349463
    • Wang YF, Gu YT, Qin GH, Zhong L, Meng YN (2013) Curcumin ameliorates the permeability of the blood–brain barrier during hypoxia by upregulating heme oxygenase-1 expression in brain microvascular endothelial cells. J Mol Neurosci 51:344–351. doi:10.1007/s12031-013-9989-4
    • (2013) J Mol Neurosci , vol.51 , pp. 344-351
    • Wang, Y.F.1    Gu, Y.T.2    Qin, G.H.3    Zhong, L.4    Meng, Y.N.5
  • 123
    • 84866124148 scopus 로고    scopus 로고
    • Altered calcium signaling following traumatic brain injury
    • PID: 2251810
    • Weber JT (2012) Altered calcium signaling following traumatic brain injury. Front Pharmacol 3:60. doi:10.3389/fphar.2012.00060. eCollection 2012
    • (2012) Front Pharmacol , vol.3 , pp. 60
    • Weber, J.T.1
  • 124
    • 84859912177 scopus 로고    scopus 로고
    • Challenging the role of adaptive immunity in neurotrauma: Rag1(−/−) mice lacking mature B and T cells do not show neuroprotection after closed head injury
    • PID: 2233578
    • Weckbach S, Neher M, Losacco JT, Bolden AL, Kulik L, Flierl MA, Bell SE, Holers VM, Stahel PF (2012) Challenging the role of adaptive immunity in neurotrauma: Rag1(−/−) mice lacking mature B and T cells do not show neuroprotection after closed head injury. J Neurotrauma 29:1233–1242. doi:10.1089/neu.2011.2169
    • (2012) J Neurotrauma , vol.29 , pp. 1233-1242
    • Weckbach, S.1    Neher, M.2    Losacco, J.T.3    Bolden, A.L.4    Kulik, L.5    Flierl, M.A.6    Bell, S.E.7    Holers, V.M.8    Stahel, P.F.9
  • 125
    • 34447527791 scopus 로고    scopus 로고
    • Pathiophysiology of traumatic brain injury
    • COI: 1:CAS:528:DC%2BD2sXovFWktLc%3D, PID: 1757339
    • Werner C, Engelhard K (2007) Pathiophysiology of traumatic brain injury. Br J Anaesth 99:4–9
    • (2007) Br J Anaesth , vol.99 , pp. 4-9
    • Werner, C.1    Engelhard, K.2
  • 127
    • 0036656798 scopus 로고    scopus 로고
    • Pathophysiology of brain edema formation
    • PID: 1248692
    • Xi G, Keep RF, Hoff JT (2002) Pathophysiology of brain edema formation. Neurosurg Clin N Am 13:371–383
    • (2002) Neurosurg Clin N Am , vol.13 , pp. 371-383
    • Xi, G.1    Keep, R.F.2    Hoff, J.T.3
  • 128
    • 84872528255 scopus 로고    scopus 로고
    • Animal models of traumatic brain injury
    • COI: 1:CAS:528:DC%2BC3sXptlOgsA%3D%3D, PID: 2332916
    • Xiong Y, Mahmood A, Chopp M (2013) Animal models of traumatic brain injury. Nat Rev Neurosci 14:128–142. doi:10.1038/nrn3407
    • (2013) Nat Rev Neurosci , vol.14 , pp. 128-142
    • Xiong, Y.1    Mahmood, A.2    Chopp, M.3
  • 129
    • 78549263013 scopus 로고    scopus 로고
    • Emerging concepts in the pathophysiology of traumatic brain injury
    • Zink BJ, Szmydynger-Chodobska J, Chodobski A (2010) Emerging concepts in the pathophysiology of traumatic brain injury. PsychiatrY Clin North Am 33:741–756. doi:10.1016/j.psc.2010.08.005
    • (2010) PsychiatrY Clin North Am , vol.33 , pp. 741-756
    • Zink, B.J.1    Szmydynger-Chodobska, J.2    Chodobski, A.3


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