Inhibition of phosphatase and tensin homolog deleted on chromosome 10 decreases rat cortical neuron injury and blood-brain barrier permeability, and improves neurological functional recovery in traumatic brain injury model

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Ding, Jun ^a   Guo, Jianyi ^a   Yuan, Qiang ^a   Yuan, Fang ^a   Chen, Hao ^a   Tian, Hengli ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BPV (PIC); EVANS BLUE; GELATINASE B; HYDROLASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CHROMOSOME 10; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; FUNCTIONAL ASSESSMENT; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NERVE INJURY; NEUROLOGICAL SEVERITY SCORE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; SURVIVAL RATE; TRAUMATIC BRAIN INJURY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN INJURIES; CEREBRAL CORTEX; CHROMOSOMES, MAMMALIAN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; MALE; MICROFILAMENT PROTEINS; NEURONS; ORGANOMETALLIC COMPOUNDS; PERMEABILITY; PHOSPHOPROTEIN PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RECOVERY OF FUNCTION;

EID: 84896699377     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080429     Document Type: Article

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