메뉴 건너뛰기




Volumn 51, Issue 2, 2013, Pages 344-351

Curcumin ameliorates the permeability of the blood-brain barrier during hypoxia by upregulating heme oxygenase-1 expression in brain microvascular endothelial cells

Author keywords

Curcumin; Heme oxygenase 1; Ischemia; OGD; Tight junction

Indexed keywords

CURCUMIN; GLUCOSE; HEME OXYGENASE 1; HORSERADISH PEROXIDASE; OCCLUDIN; OXYGEN; PROTEIN ZO1; PROTOPORPHYRIN ZINC; TIGHT JUNCTION PROTEIN;

EID: 84885184477     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-9989-4     Document Type: Article
Times cited : (64)

References (36)
  • 1
    • 84864005300 scopus 로고    scopus 로고
    • Involvement of oxidative stress in hypoxia-induced blood-brain barrier breakdown
    • 22668821 10.1016/j.mvr.2012.05.008 1:CAS:528:DC%2BC38XhtV2gur%2FM
    • Al Ahmad A, Gassmann M, Ogunshola OO (2012) Involvement of oxidative stress in hypoxia-induced blood-brain barrier breakdown. Microvasc Res 84:222-225
    • (2012) Microvasc Res , vol.84 , pp. 222-225
    • Al Ahmad, A.1    Gassmann, M.2    Ogunshola, O.O.3
  • 2
    • 84866176037 scopus 로고    scopus 로고
    • Heme oxygenase-1, oxidation, inflammation, and atherosclerosis
    • 22833723 10.3389/fphar.2012.00119
    • Araujo JA, Zhang M, Yin F (2012) Heme oxygenase-1, oxidation, inflammation, and atherosclerosis. Front Pharmacol 3:119
    • (2012) Front Pharmacol , vol.3 , pp. 119
    • Araujo, J.A.1    Zhang, M.2    Yin, F.3
  • 3
    • 78951486139 scopus 로고    scopus 로고
    • Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood-brain barrier: Cellular responses to neurotoxicants malathion and lead acetate
    • 20970449 10.1016/j.neuro.2010.10.004 1:CAS:528:DC%2BC3MXhtlSmtb0%3D
    • Balbuena P, Li W, Ehrich M (2011) Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood-brain barrier: cellular responses to neurotoxicants malathion and lead acetate. Neurotoxicology 32:58-67
    • (2011) Neurotoxicology , vol.32 , pp. 58-67
    • Balbuena, P.1    Li, W.2    Ehrich, M.3
  • 4
    • 84863316722 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress
    • 22683429 10.1016/j.lfs.2012.05.019 1:CAS:528:DC%2BC38XovVGlu7k%3D
    • Bhaskaran N, Shukla S, Kanwal R, Srivastava JK, Gupta S (2012) Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress. Life Sci 90:1027-1033
    • (2012) Life Sci , vol.90 , pp. 1027-1033
    • Bhaskaran, N.1    Shukla, S.2    Kanwal, R.3    Srivastava, J.K.4    Gupta, S.5
  • 5
  • 6
    • 79960755029 scopus 로고    scopus 로고
    • Tight junctions in brain barriers during central nervous system inflammation
    • 21338320 10.1089/ars.2011.3929 1:CAS:528:DC%2BC3MXpsVOktb8%3D
    • Coisne C, Engelhardt B (2011) Tight junctions in brain barriers during central nervous system inflammation. Antioxid Redox Signal 15:1285-1303
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1285-1303
    • Coisne, C.1    Engelhardt, B.2
  • 7
    • 84856858059 scopus 로고    scopus 로고
    • Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice
    • 21831045 10.1042/BSR20110043 1:CAS:528:DC%2BC3MXhsFaiurjE
    • Das L, Vinayak M (2012) Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice. Biosci Rep 32:161-170
    • (2012) Biosci Rep , vol.32 , pp. 161-170
    • Das, L.1    Vinayak, M.2
  • 8
    • 84862898513 scopus 로고    scopus 로고
    • Regulation of epithelial proliferation by tight junction proteins
    • 22731724 10.1111/j.1749-6632.2012.06556.x 1:CAS:528:DC%2BC38Xht1WksbjL
    • Farkas AE, Capaldo CT, Nusrat A (2012) Regulation of epithelial proliferation by tight junction proteins. Ann N Y Acad Sci 1258:115-124
    • (2012) Ann N y Acad Sci , vol.1258 , pp. 115-124
    • Farkas, A.E.1    Capaldo, C.T.2    Nusrat, A.3
  • 9
    • 80051948756 scopus 로고    scopus 로고
    • Curcumin-loaded apotransferrin nanoparticles provide efficient cellular uptake and effectively inhibit HIV-1 replication in vitro
    • 21887247 10.1371/journal.pone.0023388 1:CAS:528:DC%2BC3MXhtFyrs7rO
    • Gandapu U, Chaitanya RK, Kishore G, Reddy RC, Kondapi AK (2011) Curcumin-loaded apotransferrin nanoparticles provide efficient cellular uptake and effectively inhibit HIV-1 replication in vitro. PLoS One 6:e23388
    • (2011) PLoS One , vol.6 , pp. 23388
    • Gandapu, U.1    Chaitanya, R.K.2    Kishore, G.3    Reddy, R.C.4    Kondapi, A.K.5
  • 10
    • 84865392911 scopus 로고    scopus 로고
    • Regulation of heme oxygenase expression by alcohol, hypoxia and oxidative stress
    • 22216371 10.4331/wjbc.v2.i12.252
    • Gerjevic LN, Lu S, Chaky JP, Harrison-Findik DD (2011) Regulation of heme oxygenase expression by alcohol, hypoxia and oxidative stress. World J Biol Chem 2:252-260
    • (2011) World J Biol Chem , vol.2 , pp. 252-260
    • Gerjevic, L.N.1    Lu, S.2    Chaky, J.P.3    Harrison-Findik, D.D.4
  • 13
    • 33947201665 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage
    • 17303117 10.1016/j.ejphar.2006.12.028 1:CAS:528:DC%2BD2sXjsVWgtb4%3D
    • Jiang J, Wang W, Sun YJ, Hu M, Li F, Zhu DY (2007) Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. Eur J Pharmacol 561:54-62
    • (2007) Eur J Pharmacol , vol.561 , pp. 54-62
    • Jiang, J.1    Wang, W.2    Sun, Y.J.3    Hu, M.4    Li, F.5    Zhu, D.Y.6
  • 14
    • 39749120467 scopus 로고    scopus 로고
    • Blood brain barrier in hypoxic-ischemic conditions
    • 18289024 10.2174/156720208783565645 1:CAS:528:DC%2BD1cXlslelurY%3D
    • Kaur C, Ling EA (2008) Blood brain barrier in hypoxic-ischemic conditions. Curr Neurovasc Res 5:71-81
    • (2008) Curr Neurovasc Res , vol.5 , pp. 71-81
    • Kaur, C.1    Ling, E.A.2
  • 15
    • 84856086823 scopus 로고    scopus 로고
    • Protective effect of heme oxygenase-1 induction against hepatic injury in alcoholic steatotic liver exposed to cold ischemia/reperfusion
    • 22036622 10.1016/j.lfs.2011.10.003 1:CAS:528:DC%2BC38XhtFKhtLY%3D
    • Kim SJ, Park JG, Lee SM (2012) Protective effect of heme oxygenase-1 induction against hepatic injury in alcoholic steatotic liver exposed to cold ischemia/reperfusion. Life Sci 90:169-176
    • (2012) Life Sci , vol.90 , pp. 169-176
    • Kim, S.J.1    Park, J.G.2    Lee, S.M.3
  • 16
    • 67349134663 scopus 로고    scopus 로고
    • Curcumin mediates time and concentration dependent regulation of redox homeostasis leading to cytotoxicity in macrophage cells
    • 19344704 10.1016/j.ejphar.2009.03.060 1:CAS:528:DC%2BD1MXls1Olu7k%3D
    • Kunwar A, Sandur SK, Krishna M, Priyadarsini KI (2009) Curcumin mediates time and concentration dependent regulation of redox homeostasis leading to cytotoxicity in macrophage cells. Eur J Pharmacol 611:8-16
    • (2009) Eur J Pharmacol , vol.611 , pp. 8-16
    • Kunwar, A.1    Sandur, S.K.2    Krishna, M.3    Priyadarsini, K.I.4
  • 18
    • 80053154454 scopus 로고    scopus 로고
    • Heme oxygenase-1 could mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats
    • 21711378 10.1111/j.1440-1681.2011.05560.x
    • Liu Y, Sun XJ, Liu J, Kang ZM, Deng XM (2011) Heme oxygenase-1 could mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats. Clin Exp Pharmacol Physiol 38:675-682
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 675-682
    • Liu, Y.1    Sun, X.J.2    Liu, J.3    Kang, Z.M.4    Deng, X.M.5
  • 19
    • 84864760434 scopus 로고    scopus 로고
    • Tight junction in blood-brain barrier: An overview of structure, regulation, and regulator substances
    • doi: 10.1111/j.1755-5949.2012.00340.x
    • Liu WY, Wang ZB, Zhang LC, Wei X, Li L (2012) Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances. CNS Neurosci Ther doi: 10.1111/j.1755-5949.2012.00340.x
    • (2012) CNS Neurosci Ther
    • Liu, W.Y.1    Wang, Z.B.2    Zhang, L.C.3    Wei, X.4    Li, L.5
  • 20
    • 3042823838 scopus 로고    scopus 로고
    • Protective effect and mechanism of pretreatment with curcumin on infectious brain edema in rats
    • 14723822
    • Luo F, Huang R, Yang YJ, Yu XH (2003) Protective effect and mechanism of pretreatment with curcumin on infectious brain edema in rats. Zhonghua Er Ke Za Zhi 41:940-944
    • (2003) Zhonghua Er Ke Za Zhi , vol.41 , pp. 940-944
    • Luo, F.1    Huang, R.2    Yang, Y.J.3    Yu, X.H.4
  • 21
    • 34147165621 scopus 로고    scopus 로고
    • Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition
    • 17143561 1:CAS:528:DC%2BD2sXht1alt7c%3D
    • McNally SJ, Harrison EM, Ross JA, Garden OJ, Wigmore SJ (2007) Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition. Int J Mol Med 19:165-172
    • (2007) Int J Mol Med , vol.19 , pp. 165-172
    • McNally, S.J.1    Harrison, E.M.2    Ross, J.A.3    Garden, O.J.4    Wigmore, S.J.5
  • 22
    • 0034655773 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
    • 10889462 10.1016/S0891-5849(00)00294-X 1:CAS:528:DC%2BD3cXkslSitrk%3D
    • Motterlini R, Foresti R, Bassi R, Green CJ (2000) Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic Biol Med 28:1303-1312
    • (2000) Free Radic Biol Med , vol.28 , pp. 1303-1312
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Green, C.J.4
  • 23
    • 48349108505 scopus 로고    scopus 로고
    • Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets
    • 18299980 10.1007/s11064-008-9608-x 1:CAS:528:DC%2BD1cXptVKgu74%3D
    • Panchal HD, Vranizan K, Lee CY, Ho J, Ngai J, Timiras PS (2008) Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets. Neurochem Res 33:1701-1710
    • (2008) Neurochem Res , vol.33 , pp. 1701-1710
    • Panchal, H.D.1    Vranizan, K.2    Lee, C.Y.3    Ho, J.4    Ngai, J.5    Timiras, P.S.6
  • 24
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: Structural components and function under physiologic and pathologic conditions
    • 18040800 10.1007/s11481-006-9025-3
    • Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD (2006) Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J Neuroimmune Pharmacol 1:223-236
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 25
    • 0030793299 scopus 로고    scopus 로고
    • Evidence for pore-like opening of the blood-brain barrier following forebrain ischemia in rats
    • 9247060 10.1016/S0006-8993(97)00323-5 1:CAS:528:DyaK2sXjslKmsbk%3D
    • Preston E, Foster DO (1997) Evidence for pore-like opening of the blood-brain barrier following forebrain ischemia in rats. Brain Res 761:4-10
    • (1997) Brain Res , vol.761 , pp. 4-10
    • Preston, E.1    Foster, D.O.2
  • 26
    • 67650153191 scopus 로고    scopus 로고
    • Involvement of ROS in BBB dysfunction
    • 10.1080/10715760902751902
    • Pun PB, Lu J, Moochhala S (2003) Involvement of ROS in BBB dysfunction. Free Radic Res 43:348-364
    • (2003) Free Radic Res , vol.43 , pp. 348-364
    • Pun, P.B.1    Lu, J.2    Moochhala, S.3
  • 27
    • 78049397020 scopus 로고    scopus 로고
    • Human heme oxygenase-1 efficiently catabolizes heme in the absence of biliverdin reductase
    • 20679134 10.1124/dmd.110.034777 1:CAS:528:DC%2BC3cXhsVWqurvE
    • Reed JR, Huber WJ 3rd, Backes WL (2010) Human heme oxygenase-1 efficiently catabolizes heme in the absence of biliverdin reductase. Drug Metab Dispos 38:2060-2066
    • (2010) Drug Metab Dispos , vol.38 , pp. 2060-2066
    • Reed, J.R.1    Huber III, W.J.2    Backes, W.L.3
  • 28
    • 84863487143 scopus 로고    scopus 로고
    • Neurological diseases in relation to the blood-brain barrier
    • 22252235 10.1038/jcbfm.2011.197 1:CAS:528:DC%2BC38XpvVSjtr0%3D
    • Rosenberg GA (2012) Neurological diseases in relation to the blood-brain barrier. J Cereb Blood Flow Metab 32:1139-1151
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1139-1151
    • Rosenberg, G.A.1
  • 29
    • 0027225878 scopus 로고
    • The isolation and culture of microvascular endothelium
    • 8408265
    • Scott PA, Bicknell R (1993) The isolation and culture of microvascular endothelium. J Cell Sci 105(Pt 2):269-273
    • (1993) J Cell Sci , vol.105 , Issue.PART 2 , pp. 269-273
    • Scott, P.A.1    Bicknell, R.2
  • 30
    • 84864285568 scopus 로고    scopus 로고
    • Curcumin ameliorates hydrogen peroxide-induced epithelial barrier disruption by upregulating heme oxygenase-1 expression in human intestinal epithelial cells
    • 22392462 10.1007/s10620-012-2094-7 1:CAS:528:DC%2BC38XpsFajsbY%3D
    • Wang N, Wang G, Hao J, Ma J, Wang Y, Jiang X, Jiang H (2012) Curcumin ameliorates hydrogen peroxide-induced epithelial barrier disruption by upregulating heme oxygenase-1 expression in human intestinal epithelial cells. Dig Dis Sci 57:1792-1801
    • (2012) Dig Dis Sci , vol.57 , pp. 1792-1801
    • Wang, N.1    Wang, G.2    Hao, J.3    Ma, J.4    Wang, Y.5    Jiang, X.6    Jiang, H.7
  • 31
    • 84859160164 scopus 로고    scopus 로고
    • Role of RhoA/ROCK signaling in endothelial-monocyte-activating polypeptide II opening of the blood-tumor barrier: Role of RhoA/ROCK signaling in EMAP II opening of the BTB
    • Xie H, Xue YX, Liu LB, Liu YH, Wang P (2012) Role of RhoA/ROCK signaling in endothelial-monocyte-activating polypeptide II opening of the blood-tumor barrier: role of RhoA/ROCK signaling in EMAP II opening of the BTB. J Mol Neurosci 46(3):666-676
    • (2012) J Mol Neurosci , vol.46 , Issue.3 , pp. 666-676
    • Xie, H.1    Xue, Y.X.2    Liu, L.B.3    Liu, Y.H.4    Wang, P.5
  • 32
    • 80055019036 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in acute and chronic cerebrovascular disease
    • 21940972 10.1161/STROKEAHA.110.608257 1:CAS:528:DC%2BC3MXhtlKrsbrM
    • Yang Y, Rosenberg GA (2011) Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke 42:3323-3328
    • (2011) Stroke , vol.42 , pp. 3323-3328
    • Yang, Y.1    Rosenberg, G.A.2
  • 33
    • 84886750377 scopus 로고    scopus 로고
    • The protective effect of curcumin on cerebral ischemia reperfusion injury. Foreign Medical Sciences
    • Yang G, Cao H, Zeng YM (2005) The protective effect of curcumin on cerebral ischemia reperfusion injury. Foreign Medical Sciences. Anesthesiol Resuscitation 3:157-160
    • (2005) Anesthesiol Resuscitation , vol.3 , pp. 157-160
    • Yang, G.1    Cao, H.2    Zeng, Y.M.3
  • 34
    • 67649670106 scopus 로고    scopus 로고
    • Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
    • 19445907 10.1016/j.brainres.2009.05.009 1:CAS:528:DC%2BD1MXotl2ltLo%3D
    • Yang C, Zhang X, Fan H, Liu Y (2009) Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res 1282:133-141
    • (2009) Brain Res , vol.1282 , pp. 133-141
    • Yang, C.1    Zhang, X.2    Fan, H.3    Liu, Y.4
  • 35
    • 49849092361 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats
    • 18640105 10.1016/j.brainres.2008.06.117 1:CAS:528:DC%2BD1cXhtVejsrfJ
    • Zhao J, Zhao Y, Zheng W, Lu Y, Feng G, Yu S (2008) Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats. Brain Res 1229:224-232
    • (2008) Brain Res , vol.1229 , pp. 224-232
    • Zhao, J.1    Zhao, Y.2    Zheng, W.3    Lu, Y.4    Feng, G.5    Yu, S.6
  • 36
    • 84861200987 scopus 로고    scopus 로고
    • Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells
    • 10.1016/j.jep.2011.08.063 1:CAS:528:DC%2BC38XntlyksLY%3D
    • Zhu H, Wang Z, Xing Y, Gao Y, Ma T, Lou L, Lou J, Gao Y, Wang S, Wang YJ (2012) Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells. Ethnopharmacol 141:714-720
    • (2012) Ethnopharmacol , vol.141 , pp. 714-720
    • Zhu, H.1    Wang, Z.2    Xing, Y.3    Gao, Y.4    Ma, T.5    Lou, L.6    Lou, J.7    Gao, Y.8    Wang, S.9    Wang, Y.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.