Distribution and redistribution of HIV-1 nucleocapsid protein in immature, mature, and integrase-inhibited virions: A role for integrase in maturation

Journal of Virology

Volumn 89, Issue 19, 2015, Pages 9765-9780

  Fontana, Juan ^a   Jurado, Kellie A ^b   Cheng, Naiqian ^a   Ly, Ngoc L ^b   Fuchs, James R ^c   Gorelick, Robert J ^d   Engelman, Alan N ^b   Steven, Alasdair C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INTEGRASE INHIBITOR; GAG PROTEIN; INTEGRASE; INTEGRASE INHIBITOR; NUCLEOCAPSID PROTEIN; UNCLASSIFIED DRUG; VIRAL RIBONUCLEOPROTEIN; VIRUS PROTEIN; VIRUS RNA;

ANALYTICAL PARAMETERS; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ECCENTRIC CONDENSATE; ELECTRON DENSITY; ELECTRON IRRADIATION; ELECTRON TOMOGRAPHY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMAGING; IMMATURE VIRION; IRRADIATION; MATURE VIRION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN REDISTRIBUTION; RADIOSENSITIVITY; REVERSE TRANSCRIPTION; THREE DIMENSIONAL IMAGING; TOMO BUBBLEGRAM IMAGING; TRANSMISSION ELECTRON MICROSCOPY; VIRAL PHENOMENA AND FUNCTIONS; VIRION; VIRION MATURATION; VIRUS CORE; VIRUS LIKE AGENT; VIRUS MORPHOGENESIS; VIRUS PARTICLE; VIRUS VIRULENCE; WILD TYPE; CRYOELECTRON MICROSCOPY; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; VIRUS ASSEMBLY;

CRYOELECTRON MICROSCOPY; HEK293 CELLS; HIV INTEGRASE; HIV-1; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NUCLEOCAPSID PROTEINS; POLYMERASE CHAIN REACTION; VIRION; VIRUS ASSEMBLY;

EID: 84940994512     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01522-15     Document Type: Article

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