Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation

Brain Research

Volumn 1622, Issue , 2015, Pages 102-113

  Yabuki, Yasushi ^a   Shinoda, Yasuharu ^a   Izumi, Hisanao ^a   Ikuno, Tatuya ^a   Shioda, Norifumi ^a   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Bilateral commoncarotid artery; Ca2+calmodulin dependent protein; Dehydroepiandrosterone; kinase II; Neuroprotection; occlusion; Sigma 1 receptor

Indexed keywords

2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; MITOGEN ACTIVATED PROTEIN KINASE; PRASTERONE; PROTEIN KINASE B; SIGMA 1 OPIATE RECEPTOR; ANISOLE DERIVATIVE; N,N-DIPROPYL-2-(4-METHOXY-3-(2-PHENYLETHOXY)PHENYL)ETHYLAMINE MONOHYDROCHLORIDE; NARCOTIC ANTAGONIST; NEUROPROTECTIVE AGENT; NOOTROPIC AGENT; PROPYLAMINE; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

ADULT; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHOSPHORYLATION; BILATERAL COMMON CAROTID ARTERY OCCLUSION; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CELL DEATH; COGNITION; CONTROLLED STUDY; DRUG EFFICACY; HIPPOCAMPAL CA1 REGION; MALE; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSIENT ISCHEMIC ATTACK; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CAROTID ARTERY DISEASE; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; MEMORY DISORDERS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANISOLES; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CAROTID ARTERY DISEASES; CELL DEATH; DEHYDROEPIANDROSTERONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; MEMORY DISORDERS; MICE, INBRED C57BL; NARCOTIC ANTAGONISTS; NEURONS; NEUROPROTECTIVE AGENTS; NOOTROPIC AGENTS; PROPYLAMINES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, SIGMA;

EID: 84940927993     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.05.006     Document Type: Article

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