Stimulation of σ1-receptor restores abnormal mitochondrial Ca2 + mobilization and ATP production following cardiac hypertrophy

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 4, 2013, Pages 3082-3094

  Tagashira, Hideaki ^a   Zhang, Chen ^b   Lu, Ying Mei ^c   Hasegawa, Hideyuki ^a   Kanai, Hiroshi ^a   Han, Feng ^d   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

ATP; ATP production; Calcium signaling; Mitochondria; Sigma receptor

Indexed keywords

2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; ADENOSINE TRIPHOSPHATE; CUTAMESINE; SIGMA 1 OPIATE RECEPTOR; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTROPHIC ACTIVITY; AORTA CONSTRICTION; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFICACY; ECHOCARDIOGRAPHY; ENZYME ACTIVATION; ENZYME SYNTHESIS; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; TREATMENT DURATION; TREATMENT RESPONSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CARDIOMEGALY; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MICE; MICE, INBRED ICR; MITOCHONDRIA; PIPERAZINES; RECEPTORS, SIGMA;

MUS;

EID: 84873706586     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.12.029     Document Type: Article

References (38)

1. C.B. Taylor, M.E. Youngblood, D. Catellier, R.C. Veith, R.M. Carney, M.M. Burg, P.G. Kaufmann, J. Shuster, T. Mellman, J.A. Blumenthal, R. Krishnan, A.S. Jaffe ENRICHD Investigators Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction Arch. Gen. Psychiatry 62 7 2005 792 798
2. A. Schmidt, L. Lebel, B.K. Koe, T. Seeger, and J. Heym Sertraline potently displaces (+)-[3H]3-PPP binding to sigma sites in rat brain Eur. J. Pharmacol. 165 1989 335 336
3. 11C]SA4503 Biol. Psychiatry 62 2007 878 883
4. ++ influx and beating rate in cultured cardiac myocytes J. Pharmacol. Exp. Ther. 269 1994 1300 1309
5. M.S. Bhuiyan, H. Tagashira, and K. Fukunaga Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions Expert Opin. Ther. Targets 14 10 2010 1009 1022
6. H. Tagashira, M.S. Bhuiyan, N. Shioda, H. Hasegawa, H. Kanai, and K. Fukunaga Sigma-1 receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice Am. J. Physiol. Heart Circ. Physiol. 299 5 2010 H1535 H1545
7. M.S. Bhuiyan, and K. Fukunaga Stimulation of sigma-1 receptor signaling by dehydroepiandrosterone ameliorates pressure overload-induced hypertrophy and dysfunctions in ovariectomized rats Expert Opin. Ther. Targets 13 2009 1253 1265
8. H. Tagashira, M.S. Bhuiyan, N. Shioda, and K. Fukunaga Distinct cardioprotective effects of 17β-estradiol and dehydroepiandrosterone on pressure-overload-induced hypertrophy in ovariectomized female rats Menopause 18 12 2011 1317 1326
9. M.S. Bhuiyan, H. Tagashira, and K. Fukunaga Dehydroepiandrosterone mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding Cardiovasc. Ther. 29 4 2011 219 230
10. M.S. Bhuiyan, H. Tagashira, and K. Fukunaga Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding Eur. J. Pharmacol. 650 2-3 2011 621 628
11. K. Ito, Y. Hirooka, R. Matsukawa, M. Nakano, and K. Sunagawa Decreased brain sigma-1 receptor contributes to the relationship between heart failure and depression Cardiovasc. Res. 93 1 2012 33 40
12. 2 + signaling and cell survival Cell 131 2007 596 610
13. D.J. Bare, C.S. Kettlun, M. Liang, D.M. Bers, and G.A. Mignery Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II J. Biol. Chem. 280 2005 15912 15920
14. X. Li, A.V. Zima, F. Sheikh, L.A. Blatter, and J. Chen Endothelin-1-induced arrhythmogenic Ca2 + signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate (IP3)-receptor type 2-deficient mice Circ. Res. 96 2005 1274 1281
15. T. Uchiyama, F. Yoshikawa, A. Hishida, T. Furuichi, and K. Mikoshiba A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP(3)) absorbent traps IP(3), resulting in specific inhibition of IP(3)-mediated calcium signaling J. Biol. Chem. 277 10 2002 8106 8113
16. H. Nakayama, I. Bodi, M. Maillet, J. DeSantiago, T.L. Domeier, K. Mikoshiba, J.N. Lorenz, L.A. Blatter, D.M. Bers, and J.D. Molkentin The IP3 receptor regulates cardiac hypertrophy in response to select stimuli Circ. Res. 107 5 2010 659 666
17. K. Fujimura, J. Matsumoto, M. Niwa, T. Kobayashi, Y. Kawashima, Y. In, and T. Ishida Synthesis, structure and quantitative structure-activity relationships of sigma receptor ligands, 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3- phenylpropyl) piperazines Bioorg. Med. Chem. 5 8 1997 1675 1683
18. Y.M. Lu, F. Han, N. Shioda, S. Moriguchi, Y. Shirasaki, Z.H. Qin, and K. Fukunaga Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY-9836), a novel calmodulin antagonist Mol. Pharmacol. 75 1 2009 101 112
19. M.S. Bhuiyan, N. Shioda, M. Shibuya, Y. Iwabuchi, and K. Fukunaga Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats Hypertension 53 1 2009 57 63
20. Y.M. Lu, N. Shioda, F. Han, S. Moriguchi, J. Kasahara, Y. Shirasaki, Z.H. Qin, and K. Fukunaga Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes Biochem. Pharmacol. 74 12 2007 1727 1737
21. R.A. Bassani, J.W. Bassani, and D.M. Bers Mitochondrial and sarcolemmal Ca2 + transport reduce [Ca2 +]i during caffeine contractures in rabbit cardiac myocytes J. Physiol. 453 1992 591 608
22. W. Pendergrass, N. Wolf, and M. Poot Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues Cytometry A 61 2 2004 162 169
23. O.M. de Brito, and L. Scorrano Mitofusin 2 tethers endoplasmic reticulum to mitochondria Nature 456 7222 2008 605 610
24. G. Szabadkai, K. Bianchi, P. Várnai, D. De Stefani, M.R. Wieckowski, D. Cavagna, A.I. Nagy, T. Balla, and R. Rizzuto Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2 + channels J. Cell. Biol. 175 6 2006 901 911
25. L. Chen, Q. Gong, J.P. Stice, and A.A. Knowlton Mitochondrial OPA1, apoptosis, and heart failure Cardiovasc. Res. 84 1 2009 91 99
26. S.B. Ong, S. Subrayan, S.Y. Lim, D.M. Yellon, S.M. Davidson, and D.J. Hausenloy Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury Circulation 121 18 2010 2012 2022
27. L.C. Gomes, G. Di Benedetto, and L. Scorrano During autophagy mitochondria elongate, are spared from degradation and sustain cell viability Nat. Cell. Biol. 13 5 2011 589 598
28. Y. Chen, Y. Liu, and G.W. Dorn II Mitochondrial fusion is essential for organelle function and cardiac homeostasis Circ. Res. 109 12 2011 1327 1331
29. N. Shioda, K. Ishikawa, H. Tagashira, T. Ishizuka, H. Yawo, and K. Fukunaga Expression of a truncated form of the endoplasmic reticulum chaperone protein, sigma-1 receptor, promotes mitochondrial energy depletion and apoptosis J. Biol. Chem. 287 28 2012 23318 23331
30. C.J. Bell, N.A. Bright, G.A. Rutter, and E.J. Griffiths ATP regulation in adult rat cardiomyocytes: time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins J. Biol. Chem. 281 38 2006 28058 28067
31. R.G. Hansford, and J.B. Chappell The effect of Ca2 + on the oxidation of phosphate by blowfly flight-muscle mitochondria Biochem. Biophys. Res. Commun. 27 1967 686 692
32. R.M. Denton, P.J. Randle, and B.R. Martin Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase Biochem. J. 128 1972 161 163
33. R.M. Denton, D.A. Richards, and J.G. Chin Calcium ions and the regulation of NAD+- linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues Biochem. J. 176 1978 899 906
34. J.G. McCormack, and R.M. Denton The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex Biochem. J. 180 1979 533 544
35. I. Goldenberg, E. Grossman, K.A. Jacobson, V. Shneyvays, and A. Shainberg Angiotensin II-induced apoptosis in rat cardiomyocyte culture: a possible role of AT1 and AT2 receptors J. Hypertens. 19 9 2001 1681 1689
36. E.M. de Cavanagh, M. Ferder, F. Inserra, and L. Ferder Angiotensin II, mitochondria, cytoskeletal, and extracellular matrix connections: an integrating viewpoint Am. J. Physiol. Heart Circ. Physiol. 296 3 2009 H550 H558
37. U. Rueckschloss, M.T. Quinn, J. Holtz, and H. Morawietz Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease Arterioscler. Thromb. Vasc. Biol. 22 11 2002 1845 1851
38. G.M. Cereghetti, A. Stangherlin, O. Martins de Brito, C.R. Chang, C. Blackstone, P. Bernardi, and L. Scorrano Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria Proc. Natl. Acad. Sci. U. S. A. 105 41 2008 15803 15808