Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats

Brain Research Bulletin

Volumn 85, Issue 3-4, 2011, Pages 219-224

  Allahtavakoli, Mohammad ^a,b   Jarrott, Bevyn ^b  

^a RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cytokine; Embolic stroke; Inflammation; Neuroprotection; Sigma receptor

Indexed keywords

1 PHENYLCYCLOHEXANECARBOXYLIC ACID 2 MORPHOLINOETHYL ESTER; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN EMBOLISM; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; NERVE FIBER DEGENERATION; NEUROFILAMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; RAT; STROKE;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GAS ANALYSIS; BRAIN INFARCTION; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALITIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTREMITIES; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MALE; MORPHOLINES; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; REACTION TIME; REGIONAL BLOOD FLOW; TIME FACTORS; TOUCH;

EID: 79957799755     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2011.03.019     Document Type: Article

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