Oral l-Citrulline administration improves memory deficits following transient brain ischemia through cerebrovascular protection

Brain Research

Volumn 1520, Issue , 2013, Pages 157-167

  Yabuki, Yasushi ^a   Shioda, Norifumi ^a   Yamamoto, Yui ^a   Shigano, Miyuki ^a   Kumagai, Kota ^b   Morita, Masahiko ^b   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b KYOWA HAKKO BIO CO   (Japan)

Author keywords

Bilateral common carotid artery occlusion; Ca2+ calmodulin dependent protein kinase II; Endothelial nitric oxide synthase; l citrulline; Neuroprotection; Nitric oxide

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CITRULLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CEREBROVASCULAR ACCIDENT; COMMON CAROTID ARTERY; COMPARATIVE STUDY; CONTROLLED STUDY; DENTATE GYRUS; ENZYME ACTIVITY; FEAR; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; LATENT PERIOD; MALE; MEMORY DISORDER; MICRODIALYSIS; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PASSIVE AVOIDANCE; POSTERIOR COMMUNICATING ARTERY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSIENT ISCHEMIC ATTACK; TREATMENT DURATION;

ADMINISTRATION, ORAL; ANIMALS; CELL DEATH; CEREBROVASCULAR CIRCULATION; CITRULLINE; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICRODIALYSIS; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III;

MUS;

EID: 84879167940     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.05.011     Document Type: Article

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