Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice

Journal of Neurochemistry

Volumn 117, Issue 5, 2011, Pages 879-891

  Moriguchi, Shigeki ^a   Yamamoto, Yui ^a   Ikuno, Tatsuya ^a   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

CaM kinase II; dehydroepiandrosterone; extracellular signal regulated kinase; long term potentiation; olfactory bulbectomized mice; protein kinase C

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUTAMATE RECEPTOR 1; MARCKS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PRASTERONE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; SIGMA 1 OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVATION; FEAR; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY; MOUSE; NONHUMAN; OBJECT RELATION; OLFACTORY BULBECTOMY; PASSIVE AVOIDANCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; ANISOLES; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CA1 REGION, HIPPOCAMPAL; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; COGNITION DISORDERS; DEHYDROEPIANDROSTERONE; ELECTROPHYSIOLOGICAL PHENOMENA; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; OLFACTORY BULB; PHOSPHORYLATION; PROPYLAMINES; PROTEIN KINASE C; PSYCHOMOTOR PERFORMANCE; RECEPTORS, SIGMA; RECOGNITION (PSYCHOLOGY);

MUS;

EID: 79955646384     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07256.x     Document Type: Article

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