Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat

Neuroscience

Volumn 113, Issue 2, 2002, Pages 351-361

  Prickaerts, J ^a   Van Staveren, W C G ^a   Ik, A ^a   Markerink van Ittersum, M ^a   Niewohner U ^b   Van der Staay, F J ^b   Blokland, A ^a   De Vente, J ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b BAYER AG   (Germany)

Author keywords

Brain; Cognition; Cyclic nucleotide; Hippocampus; Learning

Indexed keywords

CYCLIC AMP; CYCLIC GMP; NITROPRUSSIDE SODIUM; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG; VARDENAFIL;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; MEMORY; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RAT; RECOGNITION; TASK PERFORMANCE;

ANIMALS; CYCLIC AMP; CYCLIC GMP; DISCRIMINATION (PSYCHOLOGY); HIPPOCAMPUS; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; MALE; PATTERN RECOGNITION, VISUAL; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; RATS; RATS, WISTAR; SULFONES; TRIAZINES;

EID: 0037067992     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00199-9     Document Type: Article

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