Developmental regulation of drug-processing genes in livers of germ-free mice

Toxicological Sciences

Volumn 147, Issue 1, 2015, Pages 84-103

  Selwyn, Felcy Pavithra ^a   Cheng, Sunny Lihua ^a   Bammler, Theo K ^a   Prasad, Bhagwat ^a   Vrana, Marc ^a   Klaassen, Curtis ^a   Cui, Julia Yue ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Drug processing genes; Germ free; Liver development

Indexed keywords

ABC TRANSPORTER G5; ABC TRANSPORTER G8; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 3A2; CARNITINE TRANSPORTER 1; CYTOCHROME P450 1A2; CYTOCHROME P450 2C; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 4A; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PREGNANE X RECEPTOR; STEROL; TRANSCRIPTOME; UNCLASSIFIED DRUG; ALANINE AMINOTRANSFERASE; CYTOCHROME P450; DRUG; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEROID RECEPTOR; XENOBIOTIC AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOWN REGULATION; DRUG PROCESSING GENE; ENZYME ACTIVITY; FEMALE; GENE; GENE CONTROL; GENE TARGETING; GERMFREE MOUSE; INTESTINE FLORA; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; ONTOGENY; PROTEIN DETERMINATION; RNA SEQUENCE; SEX DIFFERENCE; TANDEM MASS SPECTROMETRY; UPREGULATION; XENOBIOTIC METABOLISM; AGING; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; ENZYMOLOGY; GENE REGULATORY NETWORK; GENETICS; GERMFREE ANIMAL; GROWTH, DEVELOPMENT AND AGING; LIVER; METABOLISM; POLYMERASE CHAIN REACTION;

AGING; ALANINE TRANSAMINASE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOWN-REGULATION; FEMALE; GENE REGULATORY NETWORKS; GERM-FREE LIFE; LIVER; MALE; MICE; PHARMACEUTICAL PREPARATIONS; POLYMERASE CHAIN REACTION; PPAR GAMMA; RECEPTORS, STEROID; RNA, MESSENGER; TRANSCRIPTOME; XENOBIOTICS;

EID: 84940704677     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv110     Document Type: Article

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