-
1
-
-
0029845965
-
A model of host-microbial interactions in an open mammalian ecosystem
-
Bry L, Falk PG, Midtvedt T, Gordon JI (1996) A model of host-microbial interactions in an open mammalian ecosystem. Science 273: 1380-1383.
-
(1996)
Science
, vol.273
, pp. 1380-1383
-
-
Bry, L.1
Falk, P.G.2
Midtvedt, T.3
Gordon, J.I.4
-
2
-
-
0037340434
-
Angiogenins: A new class of microbicidal proteins involved in innate immunity
-
Hooper LV, Stappenbeck TS, Hong CV, Gordon JI (2003) Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol 4: 269-273.
-
(2003)
Nat Immunol
, vol.4
, pp. 269-273
-
-
Hooper, L.V.1
Stappenbeck, T.S.2
Hong, C.V.3
Gordon, J.I.4
-
3
-
-
0035793372
-
Molecular analysis of commensal host-microbial relationships in the intestine
-
Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, et al. (2001) Molecular analysis of commensal host-microbial relationships in the intestine. Science 291: 881-884.
-
(2001)
Science
, vol.291
, pp. 881-884
-
-
Hooper, L.V.1
Wong, M.H.2
Thelin, A.3
Hansson, L.4
Falk, P.G.5
-
4
-
-
0037180433
-
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
-
Stappenbeck TS, Hooper LV, Gordon JI (2002) Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A 99: 15451-15455.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15451-15455
-
-
Stappenbeck, T.S.1
Hooper, L.V.2
Gordon, J.I.3
-
5
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, et al. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 101: 15718-15723.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15718-15723
-
-
Bäckhed, F.1
Ding, H.2
Wang, T.3
Hooper, L.V.4
Koh, G.Y.5
-
7
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
-
Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, et al. (2008) Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 455: 1109-1113.
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
Ley, R.E.2
Volchkov, P.Y.3
Stranges, P.B.4
Avanesyan, L.5
-
8
-
-
55949124035
-
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermudez-Humaran LG, et al. (2008) Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 105: 16731-16736.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, L.3
Lakhdari, O.4
Bermudez-Humaran, L.G.5
-
9
-
-
0015876420
-
Differences between germ-free and conventional rats in liver microsomal metabolism of steroids
-
Einarsson K, Gustafsson JA, Gustafsson BE (1973) Differences between germ-free and conventional rats in liver microsomal metabolism of steroids. J Biol Chem 248: 3623-3630.
-
(1973)
J Biol Chem
, vol.248
, pp. 3623-3630
-
-
Einarsson, K.1
Gustafsson, J.A.2
Gustafsson, B.E.3
-
10
-
-
0015947668
-
Liver microsomal hydroxylation of steroid hormones after establishing an indigenous microflora in germfree rats
-
Einarsson K, Gustafsson JA, Gustafsson BE (1974) Liver microsomal hydroxylation of steroid hormones after establishing an indigenous microflora in germfree rats. Proc Soc Exp Biol Med 145: 48-52.
-
(1974)
Proc Soc Exp Biol Med
, vol.145
, pp. 48-52
-
-
Einarsson, K.1
Gustafsson, J.A.2
Gustafsson, B.E.3
-
11
-
-
0017665396
-
Effects of cholesterol feeding on synthesis and metabolism of cholesterol and bile acids in germfree rats
-
Gustafsson BE, Angelin B, Einarsson K, Gustafsson JA (1977) Effects of cholesterol feeding on synthesis and metabolism of cholesterol and bile acids in germfree rats. J Lipid Res 18: 717-721.
-
(1977)
J Lipid Res
, vol.18
, pp. 717-721
-
-
Gustafsson, B.E.1
Angelin, B.2
Einarsson, K.3
Gustafsson, J.A.4
-
12
-
-
0016776675
-
Influence of cholesterol feeding on liver microsomal metabolism of steroids and bile acids in conventional and germ-free rats
-
Gustafsson BE, Einarsson K, Gustafsson J (1975) Influence of cholesterol feeding on liver microsomal metabolism of steroids and bile acids in conventional and germ-free rats. J Biol Chem 250: 8496-8502.
-
(1975)
J Biol Chem
, vol.250
, pp. 8496-8502
-
-
Gustafsson, B.E.1
Einarsson, K.2
Gustafsson, J.3
-
13
-
-
34548423122
-
Endo-xenobiotic crosstalk and the regulation of cytochromes P450
-
Meyer UA (2007) Endo-xenobiotic crosstalk and the regulation of cytochromes P450. Drug Metab Rev 39: 639-646.
-
(2007)
Drug Metab Rev
, vol.39
, pp. 639-646
-
-
Meyer, U.A.1
-
14
-
-
40549086299
-
Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes
-
Roth A, Looser R, Kaufmann M, Meyer UA (2008) Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. Pharmacogenet Genomics 18: 325-337.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 325-337
-
-
Roth, A.1
Looser, R.2
Kaufmann, M.3
Meyer, U.A.4
-
15
-
-
41149102969
-
Regulatory cross-talk between drug metabolism and lipid homeostasis: Constitutive androstane receptor and pregnane X receptor increase Insig-1 expression
-
Roth A, Looser R, Kaufmann M, Blattler SM, Rencurel F, et al. (2008) Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression. Mol Pharmacol 73: 1282-1289.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1282-1289
-
-
Roth, A.1
Looser, R.2
Kaufmann, M.3
Blattler, S.M.4
Rencurel, F.5
-
16
-
-
42149103211
-
Gut flora, Toll-like receptors and nuclear receptors: A tripartite communication that tunes innate immunity in large intestine
-
Lundin A, Bok CM, Aronsson L, Björkholm B, Gustafsson JA, et al. (2008) Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine. Cell Microbiol 10: 1093-1103.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1093-1103
-
-
Lundin, A.1
Bok, C.M.2
Aronsson, L.3
Björkholm, B.4
Gustafsson, J.A.5
-
17
-
-
0017376563
-
Hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in germfree rats
-
Einarsson K, Gustafsson JA, Gustafsson BE (1977) Hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in germfree rats. Proc Soc Exp Biol Med 154: 319-321.
-
(1977)
Proc Soc Exp Biol Med
, vol.154
, pp. 319-321
-
-
Einarsson, K.1
Gustafsson, J.A.2
Gustafsson, B.E.3
-
18
-
-
0000310955
-
Bilirubin and urobilins in germfree, ex-germfree, and conventional rats
-
Gustafsson BE, Lanke LS (1960) Bilirubin and urobilins in germfree, ex-germfree, and conventional rats. J Exp Med 112: 975-981.
-
(1960)
J Exp Med
, vol.112
, pp. 975-981
-
-
Gustafsson, B.E.1
Lanke, L.S.2
-
19
-
-
12444296580
-
The impact of intestinal microflora on serum bilirubin levels
-
Vitek L, Zelenka J, Zadinova M, Malina J (2005) The impact of intestinal microflora on serum bilirubin levels. J Hepatol 42: 238-243.
-
(2005)
J Hepatol
, vol.42
, pp. 238-243
-
-
Vitek, L.1
Zelenka, J.2
Zadinova, M.3
Malina, J.4
-
20
-
-
9944265844
-
Regulatory network of lipid-sensing nuclear receptors: Roles for CAR, PXR, LXR, and FXR
-
Handschin C, Meyer UA (2005) Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. Arch Biochem Biophys 433: 387-396.
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 387-396
-
-
Handschin, C.1
Meyer, U.A.2
-
21
-
-
0034687397
-
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
-
Wei P, Zhang J, Egan-Hafley M, Liang S, Moore DD (2000) The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407: 920-923.
-
(2000)
Nature
, vol.407
, pp. 920-923
-
-
Wei, P.1
Zhang, J.2
Egan-Hafley, M.3
Liang, S.4
Moore, D.D.5
-
22
-
-
36448949469
-
Physiological function of PARbZip circadian clock-controlled transcription factors
-
Gachon F (2007) Physiological function of PARbZip circadian clock-controlled transcription factors. Ann Med 39: 562-571.
-
(2007)
Ann Med
, vol.39
, pp. 562-571
-
-
Gachon, F.1
-
23
-
-
33745329809
-
The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
-
Gachon F, Olela FF, Schaad O, Descombes P, Schibler U (2006) The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 4: 25-36.
-
(2006)
Cell Metab
, vol.4
, pp. 25-36
-
-
Gachon, F.1
Olela, F.F.2
Schaad, O.3
Descombes, P.4
Schibler, U.5
-
24
-
-
0035871311
-
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism
-
Mitsui S, Yamaguchi S, Matsuo T, Ishida Y, Okamura H (2001) Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism. Genes Dev 15: 995-1006.
-
(2001)
Genes Dev
, vol.15
, pp. 995-1006
-
-
Mitsui, S.1
Yamaguchi, S.2
Matsuo, T.3
Ishida, Y.4
Okamura, H.5
-
25
-
-
23144447140
-
CAR, the continuously advancing receptor, in drug metabolism and disease
-
Qatanani M, Moore DD (2005) CAR, the continuously advancing receptor, in drug metabolism and disease. Curr Drug Metab 6: 329-339.
-
(2005)
Curr Drug Metab
, vol.6
, pp. 329-339
-
-
Qatanani, M.1
Moore, D.D.2
-
26
-
-
14744278784
-
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex
-
Gorbacheva VY, Kondratov RV, Zhang R, Cherukuri S, Gudkov AV, et al. (2005) Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex. Proc Natl Acad Sci U S A 102: 3407-3412.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3407-3412
-
-
Gorbacheva, V.Y.1
Kondratov, R.V.2
Zhang, R.3
Cherukuri, S.4
Gudkov, A.V.5
-
27
-
-
0037790603
-
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase
-
Henderson CJ, Otto DM, Carrie D, Magnuson MA, McLaren AW, et al. (2003) Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase. J Biol Chem 278: 13480-13486.
-
(2003)
J Biol Chem
, vol.278
, pp. 13480-13486
-
-
Henderson, C.J.1
Otto, D.M.2
Carrie, D.3
Magnuson, M.A.4
McLaren, A.W.5
-
28
-
-
33846613209
-
Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity
-
Gray J, Yeo G, Hung C, Keogh J, Clayton P, et al. (2007) Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity. Int J Obes (Lond) 31: 359-364.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 359-364
-
-
Gray, J.1
Yeo, G.2
Hung, C.3
Keogh, J.4
Clayton, P.5
-
29
-
-
33845530762
-
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene
-
Gray J, Yeo GS, Cox JJ, Morton J, Adlam AL, et al. (2006) Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes 55: 3366-3371.
-
(2006)
Diabetes
, vol.55
, pp. 3366-3371
-
-
Gray, J.1
Yeo, G.S.2
Cox, J.J.3
Morton, J.4
Adlam, A.L.5
-
30
-
-
0034653422
-
BDNF regulates eating behavior and locomotor activity in mice
-
Kernie SG, Liebl DJ, Parada LF (2000) BDNF regulates eating behavior and locomotor activity in mice. Embo J 19: 1290-1300.
-
(2000)
Embo J
, vol.19
, pp. 1290-1300
-
-
Kernie, S.G.1
Liebl, D.J.2
Parada, L.F.3
-
31
-
-
0034792085
-
Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
-
Rios M, Fan G, Fekete C, Kelly J, Bates B, et al. (2001) Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15: 1748-1757.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1748-1757
-
-
Rios, M.1
Fan, G.2
Fekete, C.3
Kelly, J.4
Bates, B.5
-
32
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, et al. (2003) Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 6: 736-742.
-
(2003)
Nat Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
Cepoi, D.4
Cone, R.D.5
-
33
-
-
4043161248
-
Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice
-
Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, et al. (2004) Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol 558: 263-275.
-
(2004)
J Physiol
, vol.558
, pp. 263-275
-
-
Sudo, N.1
Chida, Y.2
Aiba, Y.3
Sonoda, J.4
Oyama, N.5
-
34
-
-
34447635075
-
Alterations in xenobiotic metabolism in the long-lived Little mice
-
Amador-Noguez D, Dean A, Huang W, Setchell K, Moore D, et al. (2007) Alterations in xenobiotic metabolism in the long-lived Little mice. Aging Cell 6: 453-470.
-
(2007)
Aging Cell
, vol.6
, pp. 453-470
-
-
Amador-Noguez, D.1
Dean, A.2
Huang, W.3
Setchell, K.4
Moore, D.5
-
35
-
-
13844298645
-
Gene expression profile of long-lived Ames dwarf mice and Little mice
-
Amador-Noguez D, Yagi K, Venable S, Darlington G (2004) Gene expression profile of long-lived Ames dwarf mice and Little mice. Aging Cell 3: 423-441.
-
(2004)
Aging Cell
, vol.3
, pp. 423-441
-
-
Amador-Noguez, D.1
Yagi, K.2
Venable, S.3
Darlington, G.4
-
36
-
-
12344309431
-
Broad spectrum detoxification: The major longevity assurance process regulated by insulin/IGF-1 signaling?
-
Gems D, McElwee JJ (2005) Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling? Mech Ageing Dev 126: 381-387.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 381-387
-
-
Gems, D.1
McElwee, J.J.2
-
37
-
-
0025234462
-
Life span, morphology, and pathology of diet-restricted germ-free and conventional Lobund-Wistar rats
-
Snyder DL, Pollard M, Wostmann BS, Luckert P (1990) Life span, morphology, and pathology of diet-restricted germ-free and conventional Lobund-Wistar rats. J Gerontol 45: B52-58.
-
(1990)
J Gerontol
, vol.45
-
-
Snyder, D.L.1
Pollard, M.2
Wostmann, B.S.3
Luckert, P.4
-
38
-
-
0026235204
-
Effects of germfree status and food restriction on longevity and growth of mice
-
Tazume S, Umehara K, Matsuzawa H, Aikawa H, Hashimoto K, et al. (1991) Effects of germfree status and food restriction on longevity and growth of mice. Jikken Dobutsu 40: 517-522.
-
(1991)
Jikken Dobutsu
, vol.40
, pp. 517-522
-
-
Tazume, S.1
Umehara, K.2
Matsuzawa, H.3
Aikawa, H.4
Hashimoto, K.5
|