Optimized approaches for quantification of drug transporters in tissues and cells by MRM proteomics

AAPS Journal

Volumn 16, Issue 4, 2014, Pages 634-648

  Prasad, Bhagwat ^a   Unadkat, Jashvant D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

drug transporters; LC MS MS; membrane proteins; MRM proteomics; quantitative proteomics

Indexed keywords

CARRIER PROTEIN; CHYMOTRYPSIN; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; SERINE PROTEINASE; TRYPSIN; DRUG;

AMINO ACID SEQUENCE; ANALYTICAL PARAMETERS; BIOINFORMATICS; DRUG TRANSPORT; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MULTIPLE REACTION MONITORING; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PREDICTION; PROCESS OPTIMIZATION; PROTEIN DATABASE; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN METABOLISM; PROTEIN TRANSPORT; PROTEOMICS; REVIEW; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; WESTERN BLOTTING; ANIMAL; CELLS; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROCEDURES;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELLS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; PHARMACEUTICAL PREPARATIONS; PROTEOMICS;

EID: 84903585415     PISSN: None     EISSN: 15507416     Source Type: Journal    
DOI: 10.1208/s12248-014-9602-y     Document Type: Review

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