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Volumn 65, Issue 5, 2015, Pages 385-395

Anorexia in human and experimental animal models: physiological aspects related to neuropeptides

Author keywords

Anorexia; Behavior; Feeding regulating neuropeptides; Hypothalamus; Rodents

Indexed keywords

CISPLATIN; NEUROPEPTIDE;

EID: 84940579413     PISSN: 18806546     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12576-015-0386-3     Document Type: Review
Times cited : (14)

References (129)
  • 2
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
    • PID: 23245604
    • Lozano R et al (2012) Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380(9859):2095–2128
    • (2012) Lancet , vol.380 , Issue.9859 , pp. 2095-2128
    • Lozano, R.1
  • 3
    • 0014260507 scopus 로고
    • Gold thioglucose damage to the satiety center: inhibition in diabetes
    • COI: 1:CAS:528:DyaF1cXmslagtg%3D%3D, PID: 5638995
    • Debons AF et al (1968) Gold thioglucose damage to the satiety center: inhibition in diabetes. Am J Physiol 214(3):652–658
    • (1968) Am J Physiol , vol.214 , Issue.3 , pp. 652-658
    • Debons, A.F.1
  • 4
    • 84964125510 scopus 로고
    • Localization of a feeding center in the hypothalamus of the rat
    • COI: 1:STN:280:DyaG3M%2FotlGrtA%3D%3D, PID: 14854036
    • Anand BK, Brobeck JR (1951) Localization of a feeding center in the hypothalamus of the rat. Proc Soc Exp Biol Med 77(2):323–324
    • (1951) Proc Soc Exp Biol Med , vol.77 , Issue.2 , pp. 323-324
    • Anand, B.K.1    Brobeck, J.R.2
  • 5
    • 76949125582 scopus 로고
    • Hypothalamic control of food intake in rats and cats
    • COI: 1:STN:280:DyaG38%2FjtF2qtg%3D%3D, PID: 14901884
    • Anand BK, Brobeck JR (1951) Hypothalamic control of food intake in rats and cats. Yale J Biol Med 24(2):123–140
    • (1951) Yale J Biol Med , vol.24 , Issue.2 , pp. 123-140
    • Anand, B.K.1    Brobeck, J.R.2
  • 6
    • 0007910227 scopus 로고
    • Evidence of a hunger motivational system in the lateral hypothalamus of the rat
    • COI: 1:STN:280:DyaF3c%2Fpt1Kqsg%3D%3D, PID: 13772612
    • Morgane PJ (1961) Evidence of a hunger motivational system in the lateral hypothalamus of the rat. Nature 191:672–674
    • (1961) Nature , vol.191 , pp. 672-674
    • Morgane, P.J.1
  • 7
    • 1842394365 scopus 로고
    • P1 site-specific recombination: nucleotide sequence of the recombining sites
    • COI: 1:CAS:528:DyaL38XktlCjt7o%3D, PID: 6954485
    • Hoess RH, Ziese M, Sternberg N (1982) P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc Natl Acad Sci USA 79(11):3398–3402
    • (1982) Proc Natl Acad Sci USA , vol.79 , Issue.11 , pp. 3398-3402
    • Hoess, R.H.1    Ziese, M.2    Sternberg, N.3
  • 8
    • 84859215897 scopus 로고    scopus 로고
    • Deciphering a neuronal circuit that mediates appetite
    • COI: 1:CAS:528:DC%2BC38Xjsleltbs%3D, PID: 22419158
    • Wu Q, Clark MS, Palmiter RD (2012) Deciphering a neuronal circuit that mediates appetite. Nature 483(7391):594–597
    • (2012) Nature , vol.483 , Issue.7391 , pp. 594-597
    • Wu, Q.1    Clark, M.S.2    Palmiter, R.D.3
  • 9
    • 84888802096 scopus 로고    scopus 로고
    • Stress and eating: a dual role for bombesin-like peptides
    • COI: 1:STN:280:DC%2BC2c3nt12msw%3D%3D, PID: 24298233
    • Merali Z et al (2013) Stress and eating: a dual role for bombesin-like peptides. Front Neurosci 7:193
    • (2013) Front Neurosci , vol.7 , pp. 193
    • Merali, Z.1
  • 10
    • 84904286653 scopus 로고    scopus 로고
    • A role of nesfatin-1/NucB2 in dehydration-induced anorexia
    • COI: 1:CAS:528:DC%2BC2cXhtlSrtLjL, PID: 24829503
    • Yoshimura M et al (2014) A role of nesfatin-1/NucB2 in dehydration-induced anorexia. Am J Physiol Regul Integr Comp Physiol 307(2):R225–R236
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.307 , Issue.2 , pp. 225-236
    • Yoshimura, M.1
  • 11
    • 0033566009 scopus 로고    scopus 로고
    • Distinct patterns of neuropeptide gene expression in the lateral hypothalamic area and arcuate nucleus are associated with dehydration-induced anorexia
    • COI: 1:CAS:528:DyaK1MXksVykurY%3D, PID: 10407047
    • Watts AG, Sanchez-Watts G, Kelly AB (1999) Distinct patterns of neuropeptide gene expression in the lateral hypothalamic area and arcuate nucleus are associated with dehydration-induced anorexia. J Neurosci 19(14):6111–6121
    • (1999) J Neurosci , vol.19 , Issue.14 , pp. 6111-6121
    • Watts, A.G.1    Sanchez-Watts, G.2    Kelly, A.B.3
  • 12
    • 84876111370 scopus 로고    scopus 로고
    • Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats
    • COI: 1:CAS:528:DC%2BC3sXlslymsbY%3D, PID: 23035922
    • Haque Z et al (2013) Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats. Stress 16(3):353–362
    • (2013) Stress , vol.16 , Issue.3 , pp. 353-362
    • Haque, Z.1
  • 13
    • 84885012557 scopus 로고    scopus 로고
    • The gene expression of the hypothalamic feeding-regulating peptides in cisplatin-induced anorexic rats
    • COI: 1:CAS:528:DC%2BC3sXht1ShtrfI, PID: 23684922
    • Yoshimura M et al (2013) The gene expression of the hypothalamic feeding-regulating peptides in cisplatin-induced anorexic rats. Peptides 46:13–19
    • (2013) Peptides , vol.46 , pp. 13-19
    • Yoshimura, M.1
  • 14
    • 0036784568 scopus 로고    scopus 로고
    • A role for cyclooxygenase-2 in lipopolysaccharide-induced anorexia in rats
    • COI: 1:STN:280:DC%2BD38voslCmsg%3D%3D, PID: 12228055
    • Lugarini F et al (2002) A role for cyclooxygenase-2 in lipopolysaccharide-induced anorexia in rats. Am J Physiol Regul Integr Comp Physiol 283(4):R862–R868
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283 , Issue.4 , pp. 862-868
    • Lugarini, F.1
  • 15
    • 84894072037 scopus 로고    scopus 로고
    • New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line
    • COI: 1:CAS:528:DC%2BC2cXjs1yntLY%3D, PID: 24347053
    • Terawaki K et al (2014) New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line. Am J Physiol Endocrinol Metab 306(4):E373–E387
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , Issue.4 , pp. 373-387
    • Terawaki, K.1
  • 16
    • 40449086557 scopus 로고    scopus 로고
    • Hypothalamic neuropeptides and appetite response in anorexia-cachexia animal
    • PID: 17827790
    • Ueta Y et al (2007) Hypothalamic neuropeptides and appetite response in anorexia-cachexia animal. Endocr J 54(6):831–838
    • (2007) Endocr J , vol.54 , Issue.6 , pp. 831-838
    • Ueta, Y.1
  • 17
    • 19444364641 scopus 로고    scopus 로고
    • Cognitive theory in anorexia nervosa and bulimia nervosa: progress, development and future directions
    • PID: 15914267
    • Cooper MJ (2005) Cognitive theory in anorexia nervosa and bulimia nervosa: progress, development and future directions. Clin Psychol Rev 25(4):511–531
    • (2005) Clin Psychol Rev , vol.25 , Issue.4 , pp. 511-531
    • Cooper, M.J.1
  • 18
    • 77951898379 scopus 로고    scopus 로고
    • Anorexia nervosa: current status and future directions
    • COI: 1:CAS:528:DC%2BC3cXisFyltr8%3D, PID: 19719398
    • Attia E (2010) Anorexia nervosa: current status and future directions. Annu Rev Med 61:425–435
    • (2010) Annu Rev Med , vol.61 , pp. 425-435
    • Attia, E.1
  • 19
    • 76349118998 scopus 로고    scopus 로고
    • Eating disorders
    • PID: 19931176
    • Treasure J, Claudino AM, Zucker N (2010) Eating disorders. Lancet 375(9714):583–593
    • (2010) Lancet , vol.375 , Issue.9714 , pp. 583-593
    • Treasure, J.1    Claudino, A.M.2    Zucker, N.3
  • 20
    • 12544251226 scopus 로고    scopus 로고
    • Richard Morton: origins of anorexia nervosa
    • COI: 1:STN:280:DC%2BD2M%2FhtFWqtw%3D%3D, PID: 15539770
    • Pearce JM (2004) Richard Morton: origins of anorexia nervosa. Eur Neurol 52(4):191–192
    • (2004) Eur Neurol , vol.52 , Issue.4 , pp. 191-192
    • Pearce, J.M.1
  • 21
    • 0031226484 scopus 로고    scopus 로고
    • Anorexia nervosa (apepsia hysterica, anorexia hysterica). 1868
    • COI: 1:STN:280:DyaK1c%2Fks1Ogug%3D%3D, PID: 9385628
    • Gull WW (1997) Anorexia nervosa (apepsia hysterica, anorexia hysterica). 1868. Obes Res 5(5):498–502
    • (1997) Obes Res , vol.5 , Issue.5 , pp. 498-502
    • Gull, W.W.1
  • 22
    • 84865636680 scopus 로고    scopus 로고
    • Epidemiology of eating disorders: incidence, prevalence and mortality rates
    • PID: 22644309
    • Smink FR, van Hoeken D, Hoek HW (2012) Epidemiology of eating disorders: incidence, prevalence and mortality rates. Curr Psychiatry Rep 14(4):406–414
    • (2012) Curr Psychiatry Rep , vol.14 , Issue.4 , pp. 406-414
    • Smink, F.R.1    van Hoeken, D.2    Hoek, H.W.3
  • 23
    • 29844438345 scopus 로고    scopus 로고
    • Perinatal factors and the risk of developing anorexia nervosa and bulimia nervosa
    • PID: 16389201
    • Favaro A, Tenconi E, Santonastaso P (2006) Perinatal factors and the risk of developing anorexia nervosa and bulimia nervosa. Arch Gen Psychiatry 63(1):82–88
    • (2006) Arch Gen Psychiatry , vol.63 , Issue.1 , pp. 82-88
    • Favaro, A.1    Tenconi, E.2    Santonastaso, P.3
  • 24
    • 0034062205 scopus 로고    scopus 로고
    • Anorexia nervosa and major depression: shared genetic and environmental risk factors
    • COI: 1:STN:280:DC%2BD3c7mtl2msA%3D%3D, PID: 10698830
    • Wade TD et al (2000) Anorexia nervosa and major depression: shared genetic and environmental risk factors. Am J Psychiatry 157(3):469–471
    • (2000) Am J Psychiatry , vol.157 , Issue.3 , pp. 469-471
    • Wade, T.D.1
  • 25
    • 19744370315 scopus 로고    scopus 로고
    • Serotonin alterations in anorexia and bulimia nervosa: new insights from imaging studies
    • COI: 1:CAS:528:DC%2BD2MXks1ahs7c%3D, PID: 15869768
    • Kaye WH et al (2005) Serotonin alterations in anorexia and bulimia nervosa: new insights from imaging studies. Physiol Behav 85(1):73–81
    • (2005) Physiol Behav , vol.85 , Issue.1 , pp. 73-81
    • Kaye, W.H.1
  • 26
    • 0036009341 scopus 로고    scopus 로고
    • Leptin in anorexia nervosa and bulimia nervosa: importance of assay technique and method of interpretation
    • COI: 1:CAS:528:DC%2BD38XjtFSns70%3D, PID: 11919545
    • Frederich R et al (2002) Leptin in anorexia nervosa and bulimia nervosa: importance of assay technique and method of interpretation. J Lab Clin Med 139(2):72–79
    • (2002) J Lab Clin Med , vol.139 , Issue.2 , pp. 72-79
    • Frederich, R.1
  • 27
    • 0031883311 scopus 로고    scopus 로고
    • Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases
    • COI: 1:STN:280:DyaK1c7isFCmsQ%3D%3D, PID: 9464208
    • Swedo SE et al (1998) Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases. Am J Psychiatry 155(2):264–271
    • (1998) Am J Psychiatry , vol.155 , Issue.2 , pp. 264-271
    • Swedo, S.E.1
  • 28
    • 26844545833 scopus 로고    scopus 로고
    • Autoantibodies against neuropeptides are associated with psychological traits in eating disorders
    • COI: 1:CAS:528:DC%2BD2MXhtFKjsb3J, PID: 16195379
    • Fetissov SO et al (2005) Autoantibodies against neuropeptides are associated with psychological traits in eating disorders. Proc Natl Acad Sci USA 102(41):14865–14870
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.41 , pp. 14865-14870
    • Fetissov, S.O.1
  • 29
    • 0034012510 scopus 로고    scopus 로고
    • Neurobiology of zinc-influenced eating behavior
    • COI: 1:CAS:528:DC%2BD3cXivFKmsL4%3D, PID: 10801965
    • Shay NF, Mangian HF (2000) Neurobiology of zinc-influenced eating behavior. J Nutr 130(5S Suppl):1493S–1499S
    • (2000) J Nutr , vol.130 , pp. 1493-1499
    • Shay, N.F.1    Mangian, H.F.2
  • 30
    • 0019186620 scopus 로고
    • Socio-cultural factors in the development of anorexia nervosa
    • COI: 1:STN:280:DyaL3M7ltFCkug%3D%3D, PID: 7208724
    • Garner DM, Garfinkel PE (1980) Socio-cultural factors in the development of anorexia nervosa. Psychol Med 10(4):647–656
    • (1980) Psychol Med , vol.10 , Issue.4 , pp. 647-656
    • Garner, D.M.1    Garfinkel, P.E.2
  • 31
    • 0036190580 scopus 로고    scopus 로고
    • Do adolescent anorexia nervosa patients have deficits in emotional functioning?
    • COI: 1:STN:280:DC%2BD383gvVChug%3D%3D, PID: 11942427
    • Zonnevijlle-Bender MJ et al (2002) Do adolescent anorexia nervosa patients have deficits in emotional functioning? Eur Child Adolesc Psychiatry 11(1):38–42
    • (2002) Eur Child Adolesc Psychiatry , vol.11 , Issue.1 , pp. 38-42
    • Zonnevijlle-Bender, M.J.1
  • 32
    • 70450183971 scopus 로고    scopus 로고
    • Emotion recognition and regulation in anorexia nervosa
    • PID: 19517577
    • Harrison A et al (2009) Emotion recognition and regulation in anorexia nervosa. Clin Psychol Psychother 16(4):348–356
    • (2009) Clin Psychol Psychother , vol.16 , Issue.4 , pp. 348-356
    • Harrison, A.1
  • 33
    • 84879268401 scopus 로고    scopus 로고
    • Anorexia nervosa, BMJ Cl
    • Lock JD, Fitzpatrick KK (2009) Anorexia nervosa. BMJ Clin Evid
    • (2009) Fitzpatrick KK
    • Lock, J.D.1
  • 34
    • 34249007481 scopus 로고    scopus 로고
    • Olanzapine therapy in anorexia nervosa: psychobiological effects
    • PID: 17519642
    • Brambilla F et al (2007) Olanzapine therapy in anorexia nervosa: psychobiological effects. Int Clin Psychopharmacol 22(4):197–204
    • (2007) Int Clin Psychopharmacol , vol.22 , Issue.4 , pp. 197-204
    • Brambilla, F.1
  • 35
    • 0029879468 scopus 로고    scopus 로고
    • The psychobiology of eating behavior in anorexia nervosa
    • COI: 1:STN:280:DyaK28zitl2ksA%3D%3D, PID: 8739112
    • Halmi KA (1996) The psychobiology of eating behavior in anorexia nervosa. Psychiatry Res 62(1):23–29
    • (1996) Psychiatry Res , vol.62 , Issue.1 , pp. 23-29
    • Halmi, K.A.1
  • 36
    • 0021740308 scopus 로고
    • Coexistence of neuropeptide Y and somatostatin in rat and human cortical and rat hypothalamic neurons
    • COI: 1:STN:280:DyaL2M7htFOjsg%3D%3D, PID: 6151631
    • Chronwall BM, Chase TN, O’Donohue TL (1984) Coexistence of neuropeptide Y and somatostatin in rat and human cortical and rat hypothalamic neurons. Neurosci Lett 52(3):213–217
    • (1984) Neurosci Lett , vol.52 , Issue.3 , pp. 213-217
    • Chronwall, B.M.1    Chase, T.N.2    O’Donohue, T.L.3
  • 37
    • 0032443807 scopus 로고    scopus 로고
    • The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
    • COI: 1:CAS:528:DyaK1cXotVGls7Y%3D, PID: 9844012
    • Broberger C et al (1998) The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc Natl Acad Sci USA 95(25):15043–15048
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.25 , pp. 15043-15048
    • Broberger, C.1
  • 38
    • 0031728655 scopus 로고    scopus 로고
    • The inter-relationship between gonadal steroids and POMC peptides, beta-endorphin and alpha-MSH, in the control of sexual behavior in the female rat
    • COI: 1:CAS:528:DyaK1cXntVSjt78%3D, PID: 9809644
    • Medina F et al (1998) The inter-relationship between gonadal steroids and POMC peptides, beta-endorphin and alpha-MSH, in the control of sexual behavior in the female rat. Peptides 19(8):1309–1316
    • (1998) Peptides , vol.19 , Issue.8 , pp. 1309-1316
    • Medina, F.1
  • 39
    • 0032498815 scopus 로고    scopus 로고
    • Down-regulated NPY receptor subtype-5 mRNA expression in genetically obese mouse brain
    • COI: 1:CAS:528:DyaK1cXitlChtbw%3D, PID: 9559948
    • Xin XG, Huang XF (1998) Down-regulated NPY receptor subtype-5 mRNA expression in genetically obese mouse brain. NeuroReport 9(4):737–741
    • (1998) NeuroReport , vol.9 , Issue.4 , pp. 737-741
    • Xin, X.G.1    Huang, X.F.2
  • 40
    • 0032535371 scopus 로고    scopus 로고
    • Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor
    • COI: 1:CAS:528:DyaK1MXmtFOi, PID: 9854049
    • Criscione L et al (1998) Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. J Clin Invest 102(12):2136–2145
    • (1998) J Clin Invest , vol.102 , Issue.12 , pp. 2136-2145
    • Criscione, L.1
  • 41
    • 0029739970 scopus 로고    scopus 로고
    • Identification of targets of leptin action in rat hypothalamus
    • COI: 1:CAS:528:DyaK28XlsFaksbg%3D, PID: 8787671
    • Schwartz MW et al (1996) Identification of targets of leptin action in rat hypothalamus. J Clin Invest 98(5):1101–1106
    • (1996) J Clin Invest , vol.98 , Issue.5 , pp. 1101-1106
    • Schwartz, M.W.1
  • 42
    • 0031797940 scopus 로고    scopus 로고
    • Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells
    • COI: 1:CAS:528:DyaK1cXnvVaiu70%3D, PID: 9867216
    • Morgan DG et al (1998) Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells. Diabetologia 41(12):1482–1491
    • (1998) Diabetologia , vol.41 , Issue.12 , pp. 1482-1491
    • Morgan, D.G.1
  • 43
    • 0035130843 scopus 로고    scopus 로고
    • AgRP(83–132) acts as an inverse agonist on the human-melanocortin-4 receptor
    • COI: 1:CAS:528:DC%2BD3MXktVKmug%3D%3D, PID: 11145747
    • Nijenhuis WA, Oosterom J, Adan RA (2001) AgRP(83–132) acts as an inverse agonist on the human-melanocortin-4 receptor. Mol Endocrinol 15(1):164–171
    • (2001) Mol Endocrinol , vol.15 , Issue.1 , pp. 164-171
    • Nijenhuis, W.A.1    Oosterom, J.2    Adan, R.A.3
  • 44
    • 79955530102 scopus 로고    scopus 로고
    • Implication of the melanocortin-3 receptor in the regulation of food intake
    • COI: 1:CAS:528:DC%2BC3MXmtFGisr8%3D, PID: 21199647
    • Irani BG et al (2011) Implication of the melanocortin-3 receptor in the regulation of food intake. Eur J Pharmacol 660(1):80–87
    • (2011) Eur J Pharmacol , vol.660 , Issue.1 , pp. 80-87
    • Irani, B.G.1
  • 45
    • 27344433932 scopus 로고    scopus 로고
    • Agouti-related peptide-expressing neurons are mandatory for feeding
    • COI: 1:CAS:528:DC%2BD2MXhtVeqs7zI, PID: 16158063
    • Gropp E et al (2005) Agouti-related peptide-expressing neurons are mandatory for feeding. Nat Neurosci 8(10):1289–1291
    • (2005) Nat Neurosci , vol.8 , Issue.10 , pp. 1289-1291
    • Gropp, E.1
  • 46
    • 84885089652 scopus 로고    scopus 로고
    • Rapid versus delayed stimulation of feeding by the endogenously released AgRP neuron mediators GABA, NPY, and AgRP
    • COI: 1:CAS:528:DC%2BC3sXhsFGnsrfN, PID: 24093681
    • Krashes MJ et al (2013) Rapid versus delayed stimulation of feeding by the endogenously released AgRP neuron mediators GABA, NPY, and AgRP. Cell Metab 18(4):588–595
    • (2013) Cell Metab , vol.18 , Issue.4 , pp. 588-595
    • Krashes, M.J.1
  • 47
    • 84864711337 scopus 로고    scopus 로고
    • Deconstruction of a neural circuit for hunger
    • COI: 1:CAS:528:DC%2BC38XhtFWjtrfE, PID: 22801496
    • Atasoy D et al (2012) Deconstruction of a neural circuit for hunger. Nature 488(7410):172–177
    • (2012) Nature , vol.488 , Issue.7410 , pp. 172-177
    • Atasoy, D.1
  • 48
    • 84896317618 scopus 로고    scopus 로고
    • An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger
    • COI: 1:CAS:528:DC%2BC2cXktV2ls7c%3D, PID: 24487620
    • Krashes MJ et al (2014) An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger. Nature 507(7491):238–242
    • (2014) Nature , vol.507 , Issue.7491 , pp. 238-242
    • Krashes, M.J.1
  • 49
    • 0021920107 scopus 로고
    • Topographical distribution of pro-opiomelanocortin-derived peptides (ACTH/beta-END/alpha-MSH) in the rat median eminence
    • COI: 1:CAS:528:DyaL2MXhs1Srsrc%3D, PID: 2983839
    • Kiss JZ et al (1985) Topographical distribution of pro-opiomelanocortin-derived peptides (ACTH/beta-END/alpha-MSH) in the rat median eminence. Brain Res 329(1–2):169–176
    • (1985) Brain Res , vol.329 , Issue.1-2 , pp. 169-176
    • Kiss, J.Z.1
  • 50
    • 0035919144 scopus 로고    scopus 로고
    • Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus
    • COI: 1:CAS:528:DC%2BD3MXktlWnur4%3D, PID: 11406287
    • Sergeyev V, Broberger C, Hokfelt T (2001) Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain Res Mol Brain Res 90(2):93–100
    • (2001) Brain Res Mol Brain Res , vol.90 , Issue.2 , pp. 93-100
    • Sergeyev, V.1    Broberger, C.2    Hokfelt, T.3
  • 51
    • 0034455629 scopus 로고    scopus 로고
    • Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat
    • COI: 1:CAS:528:DC%2BD3cXlt1Wmu7Y%3D, PID: 10875277
    • Jureus A et al (2000) Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat. Endocrinology 141(7):2703–2706
    • (2000) Endocrinology , vol.141 , Issue.7 , pp. 2703-2706
    • Jureus, A.1
  • 52
    • 0029762615 scopus 로고    scopus 로고
    • Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus
    • COI: 1:CAS:528:DyaK28XmtFeis7Y%3D, PID: 8910801
    • Mercer JG et al (1996) Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus. J Neuroendocrinol 8(10):733–735
    • (1996) J Neuroendocrinol , vol.8 , Issue.10 , pp. 733-735
    • Mercer, J.G.1
  • 53
    • 0032424694 scopus 로고    scopus 로고
    • Transcription factor STAT3 in leptin target neurons of the rat hypothalamus
    • COI: 1:STN:280:DyaK1M%2FptFOltQ%3D%3D, PID: 9873206
    • Hakansson ML, Meister B (1998) Transcription factor STAT3 in leptin target neurons of the rat hypothalamus. Neuroendocrinology 68(6):420–427
    • (1998) Neuroendocrinology , vol.68 , Issue.6 , pp. 420-427
    • Hakansson, M.L.1    Meister, B.2
  • 54
    • 57849105425 scopus 로고    scopus 로고
    • Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity
    • COI: 1:CAS:528:DC%2BD1MXptFajsw%3D%3D, PID: 19117547
    • Funato H et al (2009) Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity. Cell Metab 9(1):64–76
    • (2009) Cell Metab , vol.9 , Issue.1 , pp. 64-76
    • Funato, H.1
  • 55
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting
    • COI: 1:CAS:528:DC%2BD2MXhtVeqs7zK, PID: 16172601
    • Sternson SM, Shepherd GM, Friedman JM (2005) Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci 8(10):1356–1363
    • (2005) Nat Neurosci , vol.8 , Issue.10 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 56
    • 33846046623 scopus 로고    scopus 로고
    • Anorectic estrogen mimics leptin’s effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals
    • COI: 1:CAS:528:DC%2BD2sXhvFWisQ%3D%3D, PID: 17195839
    • Gao Q et al (2007) Anorectic estrogen mimics leptin’s effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med 13(1):89–94
    • (2007) Nat Med , vol.13 , Issue.1 , pp. 89-94
    • Gao, Q.1
  • 57
    • 0032489093 scopus 로고    scopus 로고
    • Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T et al. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92(5): p 1 page following 696
    • (1998) Cell 92(5): p 1 page following , pp. 696
    • Sakurai, T.1
  • 58
    • 1642395090 scopus 로고    scopus 로고
    • Orexin A (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats
    • COI: 1:CAS:528:DC%2BD2cXjtlagtb0%3D, PID: 14656716
    • Kiwaki K et al (2004) Orexin A (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats. Am J Physiol Endocrinol Metab 286(4):E551–E559
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , Issue.4 , pp. 551-559
    • Kiwaki, K.1
  • 59
    • 17044381714 scopus 로고    scopus 로고
    • Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons
    • COI: 1:CAS:528:DC%2BD2MXjtF2gsrY%3D, PID: 15829220
    • Williamson-Hughes PS, Grove KL, Smith MS (2005) Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons. Brain Res 1041(2):117–124
    • (2005) Brain Res , vol.1041 , Issue.2 , pp. 117-124
    • Williamson-Hughes, P.S.1    Grove, K.L.2    Smith, M.S.3
  • 60
    • 0032542294 scopus 로고    scopus 로고
    • Mice lacking melanin-concentrating hormone are hypophagic and lean
    • COI: 1:CAS:528:DyaK1MXisVeisw%3D%3D, PID: 9872314
    • Shimada M et al (1998) Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396(6712):670–674
    • (1998) Nature , vol.396 , Issue.6712 , pp. 670-674
    • Shimada, M.1
  • 61
    • 18144370824 scopus 로고    scopus 로고
    • Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions
    • COI: 1:CAS:528:DC%2BD2MXjvVOgt70%3D, PID: 15862893
    • Hara J, Yanagisawa M, Sakurai T (2005) Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions. Neurosci Lett 380(3):239–242
    • (2005) Neurosci Lett , vol.380 , Issue.3 , pp. 239-242
    • Hara, J.1    Yanagisawa, M.2    Sakurai, T.3
  • 62
    • 33748979874 scopus 로고    scopus 로고
    • Sex difference in body weight gain and leptin signaling in hypocretin/orexin deficient mouse models
    • COI: 1:CAS:528:DC%2BD28Xot1Wksb4%3D, PID: 16626839
    • Fujiki N et al (2006) Sex difference in body weight gain and leptin signaling in hypocretin/orexin deficient mouse models. Peptides 27(9):2326–2331
    • (2006) Peptides , vol.27 , Issue.9 , pp. 2326-2331
    • Fujiki, N.1
  • 63
    • 33750431055 scopus 로고    scopus 로고
    • Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat
    • COI: 1:CAS:528:DC%2BD28XhtFKmtLbN, PID: 16996040
    • Kampe J et al (2006) Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Res 1119(1):133–149
    • (2006) Brain Res , vol.1119 , Issue.1 , pp. 133-149
    • Kampe, J.1
  • 64
    • 84887008120 scopus 로고    scopus 로고
    • QRFP induces aldosterone production via PKC and T-type calcium channel-mediated pathways in human adrenocortical cells: evidence for a novel role of GPR103
    • COI: 1:CAS:528:DC%2BC3sXhvFansL7L, PID: 23964068
    • Ramanjaneya M et al (2013) QRFP induces aldosterone production via PKC and T-type calcium channel-mediated pathways in human adrenocortical cells: evidence for a novel role of GPR103. Am J Physiol Endocrinol Metab 305(9):E1049–E1058
    • (2013) Am J Physiol Endocrinol Metab , vol.305 , Issue.9 , pp. 1049-1058
    • Ramanjaneya, M.1
  • 65
    • 79958000159 scopus 로고    scopus 로고
    • QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle
    • COI: 1:CAS:528:DC%2BC3MXntFKntbo%3D, PID: 21473894
    • Primeaux SD (2011) QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides 32(6):1270–1275
    • (2011) Peptides , vol.32 , Issue.6 , pp. 1270-1275
    • Primeaux, S.D.1
  • 66
    • 84890560157 scopus 로고    scopus 로고
    • Hypothalamic QRFP: regulation of food intake and fat selection
    • COI: 1:CAS:528:DC%2BC2cXitVOrsLk%3D, PID: 23979792
    • Primeaux SD, Barnes MJ, Braymer HD (2013) Hypothalamic QRFP: regulation of food intake and fat selection. Horm Metab Res 45(13):967–974
    • (2013) Horm Metab Res , vol.45 , Issue.13 , pp. 967-974
    • Primeaux, S.D.1    Barnes, M.J.2    Braymer, H.D.3
  • 67
    • 0034279191 scopus 로고    scopus 로고
    • Disruption of arcuate/paraventricular nucleus connections changes body energy balance and response to acute stress
    • COI: 1:CAS:528:DC%2BD3cXmsVygs7c%3D, PID: 10964976
    • Bell ME et al (2000) Disruption of arcuate/paraventricular nucleus connections changes body energy balance and response to acute stress. J Neurosci 20(17):6707–6713
    • (2000) J Neurosci , vol.20 , Issue.17 , pp. 6707-6713
    • Bell, M.E.1
  • 68
    • 33646083934 scopus 로고    scopus 로고
    • Peripheral ghrelin participates in glucostatic feeding mechanisms and in the anorexigenic signalling mediated by CART and CRF neurons
    • COI: 1:CAS:528:DC%2BD28XjvVaksbc%3D, PID: 16669599
    • Solomon A, De Fanti BA, Martinez JA (2005) Peripheral ghrelin participates in glucostatic feeding mechanisms and in the anorexigenic signalling mediated by CART and CRF neurons. Nutr Neurosci 8(5–6):287–295
    • (2005) Nutr Neurosci , vol.8 , Issue.5-6 , pp. 287-295
    • Solomon, A.1    De Fanti, B.A.2    Martinez, J.A.3
  • 69
    • 84874046819 scopus 로고    scopus 로고
    • Melanocortin 4 receptor distribution in the human hypothalamus
    • COI: 1:CAS:528:DC%2BC3sXkvVGlsrk%3D, PID: 23211571
    • Siljee JE et al (2013) Melanocortin 4 receptor distribution in the human hypothalamus. Eur J Endocrinol 168(3):361–369
    • (2013) Eur J Endocrinol , vol.168 , Issue.3 , pp. 361-369
    • Siljee, J.E.1
  • 70
    • 82955233892 scopus 로고    scopus 로고
    • NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways
    • COI: 1:CAS:528:DC%2BC3MXhs1Sktr%2FM, PID: 22100407
    • Vella KR et al (2011) NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways. Cell Metab 14(6):780–790
    • (2011) Cell Metab , vol.14 , Issue.6 , pp. 780-790
    • Vella, K.R.1
  • 71
    • 27544450765 scopus 로고    scopus 로고
    • Divergence of melanocortin pathways in the control of food intake and energy expenditure
    • COI: 1:CAS:528:DC%2BD2MXht1altLnF, PID: 16269339
    • Balthasar N et al (2005) Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 123(3):493–505
    • (2005) Cell , vol.123 , Issue.3 , pp. 493-505
    • Balthasar, N.1
  • 72
    • 84920008391 scopus 로고    scopus 로고
    • The influence od melatonin receptors antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT), on melatonin-dependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophysial system. In vitro and in vivo studies
    • COI: 1:CAS:528:DC%2BC2MXksFyrtbo%3D, PID: 25554981
    • Juszczak M et al (2014) The influence od melatonin receptors antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT), on melatonin-dependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophysial system. In vitro and in vivo studies. J Physiol Pharmacol 65(6):777–784
    • (2014) J Physiol Pharmacol , vol.65 , Issue.6 , pp. 777-784
    • Juszczak, M.1
  • 73
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • COI: 1:CAS:528:DC%2BD28Xpslalu7c%3D, PID: 16988703
    • Morton GJ et al (2006) Central nervous system control of food intake and body weight. Nature 443(7109):289–295
    • (2006) Nature , vol.443 , Issue.7109 , pp. 289-295
    • Morton, G.J.1
  • 74
    • 0017049614 scopus 로고
    • Preliminary evidence for a human prolactin releasing factor
    • COI: 1:CAS:528:DyaE2sXhsFehsrY%3D, PID: 828244
    • Hagen TC, Guansing AR, Sill AJ (1976) Preliminary evidence for a human prolactin releasing factor. Neuroendocrinology 21(3):255–261
    • (1976) Neuroendocrinology , vol.21 , Issue.3 , pp. 255-261
    • Hagen, T.C.1    Guansing, A.R.2    Sill, A.J.3
  • 75
    • 0020825893 scopus 로고
    • Effects of TSH, TRH, LH and LHRH on thermoregulation and food and water intake in the rat
    • COI: 1:CAS:528:DyaL3sXltlCisbY%3D, PID: 6413877
    • Lin MT, Chu PC, Leu SY (1983) Effects of TSH, TRH, LH and LHRH on thermoregulation and food and water intake in the rat. Neuroendocrinology 37(3):206–211
    • (1983) Neuroendocrinology , vol.37 , Issue.3 , pp. 206-211
    • Lin, M.T.1    Chu, P.C.2    Leu, S.Y.3
  • 76
    • 0038742821 scopus 로고    scopus 로고
    • Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster
    • COI: 1:CAS:528:DC%2BD3sXivVClu7Y%3D, PID: 12692464
    • Steward CA et al (2003) Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster. Neuroreport 14(5):687–691
    • (2003) Neuroreport , vol.14 , Issue.5 , pp. 687-691
    • Steward, C.A.1
  • 77
    • 0023265593 scopus 로고
    • Neuropeptides TRH and cyclo(His-Pro) share neuromodulatory, but not stimulatory, action on hypothalamic neurons in vitro: implication for the regulation of feeding
    • COI: 1:CAS:528:DyaL2sXmtFaju7g%3D, PID: 2887450
    • Kow LM, Pfaff DW (1987) Neuropeptides TRH and cyclo(His-Pro) share neuromodulatory, but not stimulatory, action on hypothalamic neurons in vitro: implication for the regulation of feeding. Exp Brain Res 67(1):93–99
    • (1987) Exp Brain Res , vol.67 , Issue.1 , pp. 93-99
    • Kow, L.M.1    Pfaff, D.W.2
  • 78
    • 33749859790 scopus 로고    scopus 로고
    • Identification of nesfatin-1 as a satiety molecule in the hypothalamus
    • Oh IS et al (2006) Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 443(7112):709–712
    • (2006) Nature , vol.443 , Issue.7112 , pp. 709-712
    • Oh, I.S.1
  • 79
    • 80054933215 scopus 로고    scopus 로고
    • Minireview: nesfatin-1—an emerging new player in the brain-gut, endocrine, and metabolic axis
    • COI: 1:CAS:528:DC%2BC3MXhsVOrtb7O, PID: 21862618
    • Stengel A, Tache Y (2011) Minireview: nesfatin-1—an emerging new player in the brain-gut, endocrine, and metabolic axis. Endocrinology 152(11):4033–4038
    • (2011) Endocrinology , vol.152 , Issue.11 , pp. 4033-4038
    • Stengel, A.1    Tache, Y.2
  • 80
    • 70350371308 scopus 로고    scopus 로고
    • Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway
    • COI: 1:CAS:528:DC%2BC3cXht1eqs78%3D, PID: 19883614
    • Maejima Y et al (2009) Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway. Cell Metab 10(5):355–365
    • (2009) Cell Metab , vol.10 , Issue.5 , pp. 355-365
    • Maejima, Y.1
  • 81
    • 56149100976 scopus 로고    scopus 로고
    • Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats
    • COI: 1:CAS:528:DC%2BD1cXhtl2qtrzE, PID: 18938204
    • Inhoff T et al (2008) Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats. Peptides 29(12):2159–2168
    • (2008) Peptides , vol.29 , Issue.12 , pp. 2159-2168
    • Inhoff, T.1
  • 82
    • 47249096974 scopus 로고    scopus 로고
    • The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat
    • COI: 1:CAS:528:DC%2BD1cXoslGkurs%3D, PID: 18573315
    • Fort P et al (2008) The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat. Neuroscience 155(1):174–181
    • (2008) Neuroscience , vol.155 , Issue.1 , pp. 174-181
    • Fort, P.1
  • 83
    • 67349224649 scopus 로고    scopus 로고
    • A new anorexigenic protein, nesfatin-1
    • COI: 1:CAS:528:DC%2BD1MXltlKrsbc%3D, PID: 19452636
    • Shimizu H et al (2009) A new anorexigenic protein, nesfatin-1. Peptides 30(5):995–998
    • (2009) Peptides , vol.30 , Issue.5 , pp. 995-998
    • Shimizu, H.1
  • 84
    • 31944452253 scopus 로고    scopus 로고
    • The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
    • COI: 1:CAS:528:DC%2BD28XhtFarurk%3D, PID: 16412483
    • King BM (2006) The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 87(2):221–244
    • (2006) Physiol Behav , vol.87 , Issue.2 , pp. 221-244
    • King, B.M.1
  • 85
    • 48249113421 scopus 로고    scopus 로고
    • Steroidogenic factor 1 regulates expression of the cannabinoid receptor 1 in the ventromedial hypothalamic nucleus
    • COI: 1:CAS:528:DC%2BD1cXptlagtb4%3D, PID: 18511494
    • Kim KW et al (2008) Steroidogenic factor 1 regulates expression of the cannabinoid receptor 1 in the ventromedial hypothalamic nucleus. Mol Endocrinol 22(8):1950–1961
    • (2008) Mol Endocrinol , vol.22 , Issue.8 , pp. 1950-1961
    • Kim, K.W.1
  • 86
    • 84886219799 scopus 로고    scopus 로고
    • Endogenous opiates and behavior: 2012
    • COI: 1:CAS:528:DC%2BC3sXhvFWisbrE, PID: 24126281
    • Bodnar RJ (2013) Endogenous opiates and behavior: 2012. Peptides 50:55–95
    • (2013) Peptides , vol.50 , pp. 55-95
    • Bodnar, R.J.1
  • 87
    • 30644473109 scopus 로고    scopus 로고
    • Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
    • COI: 1:CAS:528:DC%2BD28Xht1SrtbY%3D, PID: 16423694
    • Dhillon H et al (2006) Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49(2):191–203
    • (2006) Neuron , vol.49 , Issue.2 , pp. 191-203
    • Dhillon, H.1
  • 88
    • 0033921449 scopus 로고    scopus 로고
    • Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting
    • COI: 1:CAS:528:DC%2BD3cXksFOnsb4%3D, PID: 10860677
    • Lu XY et al (2000) Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting. Horm Behav 37(4):335–344
    • (2000) Horm Behav , vol.37 , Issue.4 , pp. 335-344
    • Lu, X.Y.1
  • 89
    • 0032457292 scopus 로고    scopus 로고
    • Dehydration-associated anorexia: development and rapid reversal
    • COI: 1:CAS:528:DyaK1MXhsVSltr4%3D, PID: 10073494
    • Watts AG (1999) Dehydration-associated anorexia: development and rapid reversal. Physiol Behav 65(4–5):871–878
    • (1999) Physiol Behav , vol.65 , Issue.4-5 , pp. 871-878
    • Watts, A.G.1
  • 90
    • 0034922009 scopus 로고    scopus 로고
    • Neuropeptides and the integration of motor responses to dehydration
    • COI: 1:CAS:528:DC%2BD3MXls1Shs74%3D, PID: 11283315
    • Watts AG (2001) Neuropeptides and the integration of motor responses to dehydration. Annu Rev Neurosci 24:357–384
    • (2001) Annu Rev Neurosci , vol.24 , pp. 357-384
    • Watts, A.G.1
  • 91
    • 0036838520 scopus 로고    scopus 로고
    • Reduced feeding during water deprivation depends on hydration of the gut
    • PID: 12376399
    • Schoorlemmer GH, Evered MD (2002) Reduced feeding during water deprivation depends on hydration of the gut. Am J Physiol Regul Integr Comp Physiol 283(5):R1061–R1069
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283 , Issue.5 , pp. 1061-1069
    • Schoorlemmer, G.H.1    Evered, M.D.2
  • 92
    • 80052831117 scopus 로고    scopus 로고
    • Dehydration-anorexia derives from a reduction in meal size, but not meal number
    • COI: 1:CAS:528:DC%2BC3MXhsFehu7zO, PID: 21854794
    • Boyle CN et al (2012) Dehydration-anorexia derives from a reduction in meal size, but not meal number. Physiol Behav 105(2):305–314
    • (2012) Physiol Behav , vol.105 , Issue.2 , pp. 305-314
    • Boyle, C.N.1
  • 93
    • 77953704981 scopus 로고    scopus 로고
    • The functional architecture of dehydration-anorexia
    • COI: 1:CAS:528:DC%2BC3cXntlWqtr8%3D, PID: 20399797
    • Watts AG, Boyle CN (2010) The functional architecture of dehydration-anorexia. Physiol Behav 100(5):472–477
    • (2010) Physiol Behav , vol.100 , Issue.5 , pp. 472-477
    • Watts, A.G.1    Boyle, C.N.2
  • 94
    • 0029619183 scopus 로고
    • Neuropeptides and thirst: the temporal response of corticotropin-releasing hormone and neurotensin/neuromedin N gene expression in rat limbic forebrain neurons to drinking hypertonic saline
    • COI: 1:STN:280:DyaK28zltVOhsw%3D%3D, PID: 8748964
    • Watts AG, Kelly AB, Sanchez-Watts G (1995) Neuropeptides and thirst: the temporal response of corticotropin-releasing hormone and neurotensin/neuromedin N gene expression in rat limbic forebrain neurons to drinking hypertonic saline. Behav Neurosci 109(6):1146–1157
    • (1995) Behav Neurosci , vol.109 , Issue.6 , pp. 1146-1157
    • Watts, A.G.1    Kelly, A.B.2    Sanchez-Watts, G.3
  • 95
    • 71549134921 scopus 로고    scopus 로고
    • Prepro-orexin and feeding-related peptide receptor expression in dehydration-induced anorexia
    • COI: 1:CAS:528:DC%2BD1MXhsFGgtr3F, PID: 19800927
    • Garcia-Luna C et al (2010) Prepro-orexin and feeding-related peptide receptor expression in dehydration-induced anorexia. Regul Pept 159(1–3):54–60
    • (2010) Regul Pept , vol.159 , Issue.1-3 , pp. 54-60
    • Garcia-Luna, C.1
  • 96
    • 84864385251 scopus 로고    scopus 로고
    • Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II
    • COI: 1:CAS:528:DC%2BC38XhtFGktbnM, PID: 22719053
    • Alvarez-Salas E et al (2012) Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. Endocrinology 153(8):4067–4076
    • (2012) Endocrinology , vol.153 , Issue.8 , pp. 4067-4076
    • Alvarez-Salas, E.1
  • 97
    • 38749151881 scopus 로고    scopus 로고
    • Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure
    • COI: 1:CAS:528:DC%2BD1cXhslarsrw%3D, PID: 18191132
    • Jaimes-Hoy L, Joseph-Bravo P, de Gortari P (2008) Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure. Horm Behav 53(2):366–377
    • (2008) Horm Behav , vol.53 , Issue.2 , pp. 366-377
    • Jaimes-Hoy, L.1    Joseph-Bravo, P.2    de Gortari, P.3
  • 98
    • 19344368134 scopus 로고    scopus 로고
    • Dehydration anorexia is attenuated in oxytocin-deficient mice
    • COI: 1:CAS:528:DC%2BD2MXlsVymsb0%3D, PID: 15718385
    • Rinaman L et al (2005) Dehydration anorexia is attenuated in oxytocin-deficient mice. Am J Physiol Regul Integr Comp Physiol 288(6):R1791–R1799
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288 , Issue.6 , pp. 1791-1799
    • Rinaman, L.1
  • 99
    • 84855310208 scopus 로고    scopus 로고
    • Detection of neuronal activity and metabolism in a model of dehydration-induced anorexia in rats at 14.1 T using manganese-enhanced MRI and 1H MRS
    • COI: 1:CAS:528:DC%2BC38Xns1Oj, PID: 21544888
    • Just N, Gruetter R (2011) Detection of neuronal activity and metabolism in a model of dehydration-induced anorexia in rats at 14.1 T using manganese-enhanced MRI and 1H MRS. NMR Biomed 24(10):1326–1336
    • (2011) NMR Biomed , vol.24 , Issue.10 , pp. 1326-1336
    • Just, N.1    Gruetter, R.2
  • 100
    • 0015599330 scopus 로고
    • A screening system to determine inhibition of specific enzymes of the semiconservative DNA-synthesis and DNA-repair replication (author’s transl)
    • COI: 1:CAS:528:DyaE2cXhtVSn, PID: 4271598
    • Kocsis F, Klein W, Altmann H (1973) A screening system to determine inhibition of specific enzymes of the semiconservative DNA-synthesis and DNA-repair replication (author’s transl). Z Naturforsch C 28(3):131–135
    • (1973) Z Naturforsch C , vol.28 , Issue.3 , pp. 131-135
    • Kocsis, F.1    Klein, W.2    Altmann, H.3
  • 101
    • 79953819995 scopus 로고    scopus 로고
    • Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT(3) receptor antagonists
    • du Percie Sert N et al (2011) Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT(3) receptor antagonists. Cancer Chemother Pharmacol 67(3):667–686
    • (2011) Cancer Chemother Pharmacol , vol.67 , Issue.3 , pp. 667-686
    • du Percie Sert, N.1
  • 102
    • 77954919923 scopus 로고    scopus 로고
    • Reduced ghrelin secretion in the hypothalamus of rats due to cisplatin-induced anorexia
    • COI: 1:CAS:528:DC%2BC3cXht1Oju7%2FK, PID: 20534732
    • Yakabi K et al (2010) Reduced ghrelin secretion in the hypothalamus of rats due to cisplatin-induced anorexia. Endocrinology 151(8):3773–3782
    • (2010) Endocrinology , vol.151 , Issue.8 , pp. 3773-3782
    • Yakabi, K.1
  • 103
    • 77950338637 scopus 로고    scopus 로고
    • Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction
    • COI: 1:CAS:528:DC%2BC3cXjvFKisbk%3D, PID: 20171995
    • Yakabi K et al (2010) Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction. Regul Pept 161(1–3):97–105
    • (2010) Regul Pept , vol.161 , Issue.1-3 , pp. 97-105
    • Yakabi, K.1
  • 104
    • 84912142103 scopus 로고    scopus 로고
    • Serotonin controlling feeding and satiety
    • COI: 1:CAS:528:DC%2BC2cXhsFKqurvP, PID: 25217810
    • Voigt JP, Fink H (2015) Serotonin controlling feeding and satiety. Behav Brain Res 277:14–31
    • (2015) Behav Brain Res , vol.277 , pp. 14-31
    • Voigt, J.P.1    Fink, H.2
  • 105
    • 0034753891 scopus 로고    scopus 로고
    • Hypothalamic appetite-regulating neuropeptide mRNA levels in cachectic nude mice bearing human tumor cells
    • COI: 1:CAS:528:DC%2BD3MXns1Wluro%3D, PID: 11586496
    • Nara-ashizawa N et al (2001) Hypothalamic appetite-regulating neuropeptide mRNA levels in cachectic nude mice bearing human tumor cells. Metabolism 50(10):1213–1219
    • (2001) Metabolism , vol.50 , Issue.10 , pp. 1213-1219
    • Nara-Ashizawa, N.1
  • 106
    • 84921761442 scopus 로고    scopus 로고
    • Rikkunshito, a ghrelin potentiator, ameliorates anorexia-cachexia syndrome
    • PID: 25540621
    • Fujitsuka N, Uezono Y (2014) Rikkunshito, a ghrelin potentiator, ameliorates anorexia-cachexia syndrome. Front Pharmacol 5:271
    • (2014) Front Pharmacol , vol.5 , pp. 271
    • Fujitsuka, N.1    Uezono, Y.2
  • 107
    • 55749085001 scopus 로고    scopus 로고
    • Cachexia: a new definition
    • COI: 1:CAS:528:DC%2BD1cXhsVWrsbzI, PID: 18718696
    • Evans WJ et al (2008) Cachexia: a new definition. Clin Nutr 27(6):793–799
    • (2008) Clin Nutr , vol.27 , Issue.6 , pp. 793-799
    • Evans, W.J.1
  • 108
    • 84920537645 scopus 로고    scopus 로고
    • Cancer cachexia syndrome: pathogenesis, diagnosis, and new therapeutic options
    • COI: 1:CAS:528:DC%2BC2cXitFOmsrrO, PID: 25513730
    • Mondello P et al (2015) Cancer cachexia syndrome: pathogenesis, diagnosis, and new therapeutic options. Nutr Cancer 67(1):12–26
    • (2015) Nutr Cancer , vol.67 , Issue.1 , pp. 12-26
    • Mondello, P.1
  • 109
    • 84873406669 scopus 로고    scopus 로고
    • Understanding the mechanisms and treatment options in cancer cachexia
    • COI: 1:CAS:528:DC%2BC3sXhvV2ntLg%3D, PID: 23207794
    • Fearon K, Arends J, Baracos V (2013) Understanding the mechanisms and treatment options in cancer cachexia. Nat Rev Clin Oncol 10(2):90–99
    • (2013) Nat Rev Clin Oncol , vol.10 , Issue.2 , pp. 90-99
    • Fearon, K.1    Arends, J.2    Baracos, V.3
  • 110
    • 14844320127 scopus 로고    scopus 로고
    • Cancer anorexia-cachexia syndrome: cytokines and neuropeptides
    • COI: 1:CAS:528:DC%2BD2cXmsVShsbo%3D, PID: 15192446
    • Ramos EJ et al (2004) Cancer anorexia-cachexia syndrome: cytokines and neuropeptides. Curr Opin Clin Nutr Metab Care 7(4):427–434
    • (2004) Curr Opin Clin Nutr Metab Care , vol.7 , Issue.4 , pp. 427-434
    • Ramos, E.J.1
  • 111
    • 20144377885 scopus 로고    scopus 로고
    • Therapy insight: cancer anorexia-cachexia syndrome—when all you can eat is yourself
    • COI: 1:CAS:528:DC%2BD2MXktlWrtb0%3D, PID: 16264909
    • Laviano A et al (2005) Therapy insight: cancer anorexia-cachexia syndrome—when all you can eat is yourself. Nat Clin Pract Oncol 2(3):158–165
    • (2005) Nat Clin Pract Oncol , vol.2 , Issue.3 , pp. 158-165
    • Laviano, A.1
  • 112
    • 29144513918 scopus 로고    scopus 로고
    • Prevention and treatment of cancer cachexia: new insights into an old problem
    • COI: 1:CAS:528:DC%2BD2MXhtlCktL3N, PID: 16314085
    • Muscaritoli M et al (2006) Prevention and treatment of cancer cachexia: new insights into an old problem. Eur J Cancer 42(1):31–41
    • (2006) Eur J Cancer , vol.42 , Issue.1 , pp. 31-41
    • Muscaritoli, M.1
  • 113
    • 0032518563 scopus 로고    scopus 로고
    • Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
    • COI: 1:CAS:528:DyaK1cXmtF2gsg%3D%3D, PID: 9435324
    • Jensen PB et al (1998) Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus. J Clin Invest 101(2):503–510
    • (1998) J Clin Invest , vol.101 , Issue.2 , pp. 503-510
    • Jensen, P.B.1
  • 114
    • 0032566851 scopus 로고    scopus 로고
    • NPY messenger RNA is increased in medial hypothalamus of anorectic tumor-bearing rats
    • PID: 9802428
    • Chance WT et al (1998) NPY messenger RNA is increased in medial hypothalamus of anorectic tumor-bearing rats. Regul Pept 75–76:347–353
    • (1998) Regul Pept , vol.75-76 , pp. 347-353
    • Chance, W.T.1
  • 115
    • 0035212781 scopus 로고    scopus 로고
    • Cachexia in MAC16 adenocarcinoma: suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y
    • COI: 1:CAS:528:DC%2BD3MXptFOhsbo%3D, PID: 11739612
    • Bing C et al (2001) Cachexia in MAC16 adenocarcinoma: suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y. J Neurochem 79(5):1004–1012
    • (2001) J Neurochem , vol.79 , Issue.5 , pp. 1004-1012
    • Bing, C.1
  • 116
    • 0031844188 scopus 로고    scopus 로고
    • Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells
    • COI: 1:CAS:528:DyaK1cXlsVyjtLs%3D, PID: 9688694
    • Plata-Salaman CR, Ilyin SE, Gayle D (1998) Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells. Am J Physiol 275(2 Pt 2):R566–R573
    • (1998) Am J Physiol , vol.275 , pp. 566-573
    • Plata-Salaman, C.R.1    Ilyin, S.E.2    Gayle, D.3
  • 117
    • 0029782842 scopus 로고    scopus 로고
    • Assessment of feeding response of tumor-bearing rats to hypothalamic injection and infusion of neuropeptide Y
    • COI: 1:CAS:528:DyaK28Xkslyht78%3D, PID: 8844769
    • Chance WT et al (1996) Assessment of feeding response of tumor-bearing rats to hypothalamic injection and infusion of neuropeptide Y. Peptides 17(5):797–801
    • (1996) Peptides , vol.17 , Issue.5 , pp. 797-801
    • Chance, W.T.1
  • 118
    • 0027401526 scopus 로고
    • Alterations in hypothalamic NPY and CRF in anorexic tumor-bearing rats
    • COI: 1:CAS:528:DyaK3sXksVKmsLY%3D, PID: 8476042
    • McCarthy HD et al (1993) Alterations in hypothalamic NPY and CRF in anorexic tumor-bearing rats. Am J Physiol 264(4 Pt 1):E638–E643
    • (1993) Am J Physiol , vol.264 , pp. 638-643
    • McCarthy, H.D.1
  • 119
    • 77957783143 scopus 로고    scopus 로고
    • Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis
    • COI: 1:CAS:528:DC%2BC3cXhtlSjsrzL, PID: 20833197
    • Nakhate KT et al (2010) Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis. Pharmacol Biochem Behav 97(2):340–349
    • (2010) Pharmacol Biochem Behav , vol.97 , Issue.2 , pp. 340-349
    • Nakhate, K.T.1
  • 120
    • 84861716770 scopus 로고    scopus 로고
    • Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia
    • COI: 1:CAS:528:DC%2BC38Xls1Wksb0%3D, PID: 22460823
    • Suzuki M et al (2012) Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia. Synapse 66(8):747–751
    • (2012) Synapse , vol.66 , Issue.8 , pp. 747-751
    • Suzuki, M.1
  • 121
    • 79960751196 scopus 로고    scopus 로고
    • Potentiation of ghrelin signaling attenuates cancer anorexia-cachexia and prolongs survival
    • COI: 1:STN:280:DC%2BC38fjtVansQ%3D%3D, PID: 22832525
    • Fujitsuka N et al (2011) Potentiation of ghrelin signaling attenuates cancer anorexia-cachexia and prolongs survival. Transl Psychiatry 1:e23
    • (2011) Transl Psychiatry , vol.1 , pp. 23
    • Fujitsuka, N.1
  • 122
    • 0032512915 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP) and hypercalcaemia
    • COI: 1:CAS:528:DyaK1cXisFGrsrc%3D, PID: 9741325
    • Grill V, Rankin W, Martin TJ (1998) Parathyroid hormone-related protein (PTHrP) and hypercalcaemia. Eur J Cancer 34(2):222–229
    • (1998) Eur J Cancer , vol.34 , Issue.2 , pp. 222-229
    • Grill, V.1    Rankin, W.2    Martin, T.J.3
  • 123
    • 0023228836 scopus 로고
    • A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression
    • COI: 1:CAS:528:DyaL1cXhslSgtQ%3D%3D, PID: 3616618
    • Suva LJ et al (1987) A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science 237(4817):893–896
    • (1987) Science , vol.237 , Issue.4817 , pp. 893-896
    • Suva, L.J.1
  • 124
    • 0024241270 scopus 로고
    • Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors
    • COI: 1:CAS:528:DyaL1cXmt1Olur8%3D, PID: 2846659
    • Kukreja SC et al (1988) Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors. J Clin Invest 82(5):1798–1802
    • (1988) J Clin Invest , vol.82 , Issue.5 , pp. 1798-1802
    • Kukreja, S.C.1
  • 125
    • 0035479861 scopus 로고    scopus 로고
    • Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen
    • COI: 1:CAS:528:DC%2BD3MXms1KgsL4%3D, PID: 11668474
    • Iguchi H et al (2001) Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen. Int J Cancer 94(1):24–27
    • (2001) Int J Cancer , vol.94 , Issue.1 , pp. 24-27
    • Iguchi, H.1
  • 126
    • 22244464504 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts
    • COI: 1:CAS:528:DC%2BD2MXmtl2ku78%3D, PID: 15800941
    • Onuma E et al (2005) Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts. Int J Cancer 116(3):471–478
    • (2005) Int J Cancer , vol.116 , Issue.3 , pp. 471-478
    • Onuma, E.1
  • 127
    • 33846315463 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides
    • COI: 1:CAS:528:DC%2BD2sXotlWq, PID: 17200368
    • Hashimoto H et al (2007) Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides. Clin Cancer Res 13(1):292–298
    • (2007) Clin Cancer Res , vol.13 , Issue.1 , pp. 292-298
    • Hashimoto, H.1
  • 128
    • 84906934662 scopus 로고    scopus 로고
    • Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
    • COI: 1:CAS:528:DC%2BC2cXhsVyhurjJ, PID: 25043053
    • Kir S et al (2014) Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia. Nature 513(7516):100–104
    • (2014) Nature , vol.513 , Issue.7516 , pp. 100-104
    • Kir, S.1
  • 129
    • 0028829958 scopus 로고
    • Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain
    • COI: 1:CAS:528:DyaK2MXjt1WitbY%3D, PID: 7723628
    • Weaver DR et al (1995) Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain. Brain Res Mol Brain Res 28(2):296–310
    • (1995) Brain Res Mol Brain Res , vol.28 , Issue.2 , pp. 296-310
    • Weaver, D.R.1


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