메뉴 건너뛰기




Volumn 54, Issue 6, 2007, Pages 831-838

Hypothalamic neuropeptides and appetite response in anorexia-cachexia animal

Author keywords

Anorexia; Cachexia; Hypothalamus; Neuropeptides; Parathyroid hormone related protein

Indexed keywords

NEUROPEPTIDE;

EID: 40449086557     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.KR-111     Document Type: Review
Times cited : (11)

References (62)
  • 2
    • 0033567912 scopus 로고    scopus 로고
    • Cancer anorexia-cachexia syndrome: Are neuropeptides the key?
    • Inui A (1999) Cancer anorexia-cachexia syndrome: are neuropeptides the key? Cancer Res 59: 4493-4501.
    • (1999) Cancer Res , vol.59 , pp. 4493-4501
    • Inui, A.1
  • 3
    • 0000067107 scopus 로고    scopus 로고
    • Genetics and pathophysiology of human obesity
    • Cummings DE, Schwartz MW (2003) Genetics and pathophysiology of human obesity. Annu Rev Med 54: 453-471.
    • (2003) Annu Rev Med , vol.54 , pp. 453-471
    • Cummings, D.E.1    Schwartz, M.W.2
  • 4
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS (1999) Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20: 68-100.
    • (1999) Endocr Rev , vol.20 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 5
    • 0000139058 scopus 로고
    • Input-output organization in the hypothalamus relating to food intake behavior
    • New York: Marcel Dekker, p
    • Oomura Y (1980) Input-output organization in the hypothalamus relating to food intake behavior. Handbook of the Hypothalamus (Vol. 2). New York: Marcel Dekker, p. 557-620.
    • (1980) Handbook of the Hypothalamus , vol.2 , pp. 557-620
    • Oomura, Y.1
  • 7
    • 0000555383 scopus 로고
    • Neuropeptide Y injected in the paraventricular hypothalamus: A powerful stimulant of feeding behavior
    • Stanley BG, Leibowitz SF (1985) Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proc Natl Acad Sci USA 82: 3940-3943.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3940-3943
    • Stanley, B.G.1    Leibowitz, S.F.2
  • 8
    • 0030614331 scopus 로고    scopus 로고
    • Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
    • Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD (1997) Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385: 165-168.
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, R.D.5
  • 10
    • 0032457292 scopus 로고    scopus 로고
    • Dehydration-associated anorexia: Development and rapid reversal
    • Watts AG (1999) Dehydration-associated anorexia: development and rapid reversal. Physiol Behav 65: 871-878.
    • (1999) Physiol Behav , vol.65 , pp. 871-878
    • Watts, A.G.1
  • 11
    • 0034922009 scopus 로고    scopus 로고
    • Neuropeptides and the integration of motor responses to dehydration
    • Watts AG (2001) Neuropeptides and the integration of motor responses to dehydration. Annu Rev Neurosci 24: 357-384.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 357-384
    • Watts, A.G.1
  • 12
    • 0029619183 scopus 로고
    • Neuropeptides and thirst: The temporal response of corticotropin-releasing hormone and neurotensin/neuromedin N gene expression in rat limbic forebrain neurons to drink hypertonic saline
    • Watts AG, Kelly AB, Sanchez-Watts G (1995) Neuropeptides and thirst: the temporal response of corticotropin-releasing hormone and neurotensin/neuromedin N gene expression in rat limbic forebrain neurons to drink hypertonic saline. Behav Neurosci 109: 1146-1157.
    • (1995) Behav Neurosci , vol.109 , pp. 1146-1157
    • Watts, A.G.1    Kelly, A.B.2    Sanchez-Watts, G.3
  • 13
    • 0033566009 scopus 로고    scopus 로고
    • Distinct patterns of neuropeptide gene expression in the lateral hypothalamic area and arcuate nucleus are associated with dehydration-induced anorexia
    • Watts AG, Sanchez-Watts G, Kelly AB (1999) Distinct patterns of neuropeptide gene expression in the lateral hypothalamic area and arcuate nucleus are associated with dehydration-induced anorexia. J Neurosci 19(14):6111-6121.
    • (1999) J Neurosci , vol.19 , Issue.14 , pp. 6111-6121
    • Watts, A.G.1    Sanchez-Watts, G.2    Kelly, A.B.3
  • 14
    • 0023865313 scopus 로고
    • Effects of chronic infusion of lipoplysaccharide on food intake and body temperature of the rat
    • O'Reilly B, Vander AJ, Kluger MJ (1988) Effects of chronic infusion of lipoplysaccharide on food intake and body temperature of the rat. Physiol Behav 42: 287-291.
    • (1988) Physiol Behav , vol.42 , pp. 287-291
    • O'Reilly, B.1    Vander, A.J.2    Kluger, M.J.3
  • 17
    • 0029859221 scopus 로고    scopus 로고
    • Dissociation of temperature changes and anorexia after experimental colitis and LPS administration in rats
    • Larson SJ, Collins SM, Weingarten HP (1996) Dissociation of temperature changes and anorexia after experimental colitis and LPS administration in rats. Am J Physiol Regul Integr Comp Physiol 271: R967-972.
    • (1996) Am J Physiol Regul Integr Comp Physiol , vol.271
    • Larson, S.J.1    Collins, S.M.2    Weingarten, H.P.3
  • 18
    • 0021269113 scopus 로고
    • The role of fever in appetite suppression after endotoxin administration
    • McCarthy DO, Kluger MJ, Vander AJ (1984) The role of fever in appetite suppression after endotoxin administration. Am J Clin Nutr 40: 310-316.
    • (1984) Am J Clin Nutr , vol.40 , pp. 310-316
    • McCarthy, D.O.1    Kluger, M.J.2    Vander, A.J.3
  • 20
    • 0028846219 scopus 로고
    • Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain: Its possible role in the febrile response
    • Cao C, Matsumura K, Yamagata K, Watanabe Y (1995) Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain: its possible role in the febrile response. Brain Res 697: 187-196.
    • (1995) Brain Res , vol.697 , pp. 187-196
    • Cao, C.1    Matsumura, K.2    Yamagata, K.3    Watanabe, Y.4
  • 21
    • 0030787985 scopus 로고    scopus 로고
    • Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain
    • Cao CY, Matsumura K, Yamagata K, Watanabe Y (1997) Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain. Am J Physiol Regul Integr Comp Physiol 272: R1712-1725.
    • (1997) Am J Physiol Regul Integr Comp Physiol , vol.272
    • Cao, C.Y.1    Matsumura, K.2    Yamagata, K.3    Watanabe, Y.4
  • 22
    • 0032699574 scopus 로고    scopus 로고
    • Feeding status and bacterial LPS-induced cytokine and neuropeptide gene expression in hypothalamus
    • Gayle D, Ilyin SE, Plata-Salaman CR (1999) Feeding status and bacterial LPS-induced cytokine and neuropeptide gene expression in hypothalamus. Am J Physiol Regul Integr Comp Physiol 46: R1188-1195.
    • (1999) Am J Physiol Regul Integr Comp Physiol , vol.46
    • Gayle, D.1    Ilyin, S.E.2    Plata-Salaman, C.R.3
  • 23
    • 0035919144 scopus 로고    scopus 로고
    • Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus
    • Sergeyev V, Broberger C, Hokfelt T (2001) Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain Res Mol Brain Res 90(2): 93-100.
    • (2001) Brain Res Mol Brain Res , vol.90 , Issue.2 , pp. 93-100
    • Sergeyev, V.1    Broberger, C.2    Hokfelt, T.3
  • 24
    • 33747626724 scopus 로고    scopus 로고
    • MyD88 is a key mediator of anorexia, but not weight loss, induced by lipopolysaccharide and interleukin-1b
    • Ogimoto K, Harris MK, Wisse BE (2006) MyD88 is a key mediator of anorexia, but not weight loss, induced by lipopolysaccharide and interleukin-1b. Endocrinology 147: 4445-4453.
    • (2006) Endocrinology , vol.147 , pp. 4445-4453
    • Ogimoto, K.1    Harris, M.K.2    Wisse, B.E.3
  • 26
    • 0035000097 scopus 로고    scopus 로고
    • Cancer anorexia and cachexia
    • Tisdale MJ (2001) Cancer anorexia and cachexia. Nutrition 17: 438-442.
    • (2001) Nutrition , vol.17 , pp. 438-442
    • Tisdale, M.J.1
  • 27
    • 0030688961 scopus 로고    scopus 로고
    • Bruera E (1997) ABC of palliative care. Anorexia, cachexia, and nutrition. BMJ 315: 1219-1222
    • Bruera E (1997) ABC of palliative care. Anorexia, cachexia, and nutrition. BMJ 315: 1219-1222
  • 28
    • 0030665384 scopus 로고    scopus 로고
    • Biology of cachexia
    • Tisdale MJ (1997) Biology of cachexia. J Natl Cancer Inst 89: 1763-1773.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1763-1773
    • Tisdale, M.J.1
  • 29
    • 0028246585 scopus 로고
    • Chemokines/intercrines and central regulation of feeding
    • Plata-Salaman CR, Borkoski JP (1994) Chemokines/intercrines and central regulation of feeding. Am J Physiol 266: R1711-1715.
    • (1994) Am J Physiol , vol.266
    • Plata-Salaman, C.R.1    Borkoski, J.P.2
  • 30
    • 0031844188 scopus 로고    scopus 로고
    • Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells
    • Plata-Salaman CR, Ilyin SE, Gayle D (1998) Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells. Am J Physiol 275: R566-573.
    • (1998) Am J Physiol , vol.275
    • Plata-Salaman, C.R.1    Ilyin, S.E.2    Gayle, D.3
  • 31
    • 0028845449 scopus 로고
    • Hypothalamic response to starvation: Implications for the study of wasting disorders
    • Schwartz MW, Dallman MF, Woods SC (1995) Hypothalamic response to starvation: implications for the study of wasting disorders. Am J Physiol 269: R949-957.
    • (1995) Am J Physiol , vol.269
    • Schwartz, M.W.1    Dallman, M.F.2    Woods, S.C.3
  • 39
    • 0034065518 scopus 로고    scopus 로고
    • Effects of food restriction on the hypothalamic prepro-orexin gene expression in genetically obese mice
    • Yamamoto Y, Ueta Y, Serino R, Nomura M, Shibuya I, Yamashita H (2000) Effects of food restriction on the hypothalamic prepro-orexin gene expression in genetically obese mice. Brain Res Bull 51: 515-521.
    • (2000) Brain Res Bull , vol.51 , pp. 515-521
    • Yamamoto, Y.1    Ueta, Y.2    Serino, R.3    Nomura, M.4    Shibuya, I.5    Yamashita, H.6
  • 40
    • 0036710963 scopus 로고    scopus 로고
    • Expressions of the prepro-orexin and orexin type 2 receptor genes in obese rat
    • Yamamoto Y, Ueta Y, Yamashita H, Asayama K, Shirahata A (2002) Expressions of the prepro-orexin and orexin type 2 receptor genes in obese rat. Peptides 23: 1689-1696.
    • (2002) Peptides , vol.23 , pp. 1689-1696
    • Yamamoto, Y.1    Ueta, Y.2    Yamashita, H.3    Asayama, K.4    Shirahata, A.5
  • 42
    • 0032518563 scopus 로고    scopus 로고
    • Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
    • Jensen PB, Blume N, Mikkelsen JD, Larsen PJ, Jensen HI, Holst JJ, Madsen OD (1998) Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus. J Clin Invest 101: 503-510.
    • (1998) J Clin Invest , vol.101 , pp. 503-510
    • Jensen, P.B.1    Blume, N.2    Mikkelsen, J.D.3    Larsen, P.J.4    Jensen, H.I.5    Holst, J.J.6    Madsen, O.D.7
  • 43
    • 0032566851 scopus 로고    scopus 로고
    • NPY messenger RNA is increased in medial hypothalamus of anorectic tumor-bearing rats
    • Chance WT, Sheriff S, Kasckow JW, Regmi A, Balasubramaniam A (1998) NPY messenger RNA is increased in medial hypothalamus of anorectic tumor-bearing rats. Regul Pept 75-76: 347-353.
    • (1998) Regul Pept , vol.75-76 , pp. 347-353
    • Chance, W.T.1    Sheriff, S.2    Kasckow, J.W.3    Regmi, A.4    Balasubramaniam, A.5
  • 44
    • 0035212781 scopus 로고    scopus 로고
    • Cachexia in MAC16 adenocarcinoma: Suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y
    • Chen B, Taylor S, Tisdale MJ, Williams G (2001) Cachexia in MAC16 adenocarcinoma: suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y. J Neurochem 79: 1004-1012.
    • (2001) J Neurochem , vol.79 , pp. 1004-1012
    • Chen, B.1    Taylor, S.2    Tisdale, M.J.3    Williams, G.4
  • 46
    • 0035527487 scopus 로고    scopus 로고
    • Response of hypothalamic NPY mRNAs to a negative energy balance is less sensitive in cachectic mice bearing human tumor cells
    • Nara-ashizawa N, Tsukada T, Maruyama K, Akiyama Y, Kajimura N, Yamaguchi K (2001) Response of hypothalamic NPY mRNAs to a negative energy balance is less sensitive in cachectic mice bearing human tumor cells. Nutr Cancer 41: 111-118.
    • (2001) Nutr Cancer , vol.41 , pp. 111-118
    • Nara-ashizawa, N.1    Tsukada, T.2    Maruyama, K.3    Akiyama, Y.4    Kajimura, N.5    Yamaguchi, K.6
  • 47
    • 0842287511 scopus 로고    scopus 로고
    • Refractory hypothalamic alpha-MSH satiety and AGRP feeding systems in rats bearing MCA sarcomas
    • Chance WT, Sheriff S, Dayal R, Balasubramaniam A (2003) Refractory hypothalamic alpha-MSH satiety and AGRP feeding systems in rats bearing MCA sarcomas. Peptides 24: 1909-1919.
    • (2003) Peptides , vol.24 , pp. 1909-1919
    • Chance, W.T.1    Sheriff, S.2    Dayal, R.3    Balasubramaniam, A.4
  • 49
    • 0032512915 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP) and hypercalcaemia
    • Grill V, Rankin W, Martin TJ (1998) Parathyroid hormone-related protein (PTHrP) and hypercalcaemia. Eur J Cancer 34: 222-229.
    • (1998) Eur J Cancer , vol.34 , pp. 222-229
    • Grill, V.1    Rankin, W.2    Martin, T.J.3
  • 51
    • 0024241270 scopus 로고
    • Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors
    • Kukreja SC, Shevrin DH, Wimbiscus SA, Ebeling PR, Danks JA, Rodda CP, Wood WI, Martin TJ (1988) Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors. J Clin Invest 82: 1798-1802.
    • (1988) J Clin Invest , vol.82 , pp. 1798-1802
    • Kukreja, S.C.1    Shevrin, D.H.2    Wimbiscus, S.A.3    Ebeling, P.R.4    Danks, J.A.5    Rodda, C.P.6    Wood, W.I.7    Martin, T.J.8
  • 52
    • 0027233498 scopus 로고
    • Passive immunization with anti-parathyroid hormone-related protein monoclonal antibody markedly prolongs survival time of hypercalcemic nude mice bearing transplanted human PTHrP-producing tumors
    • Sato K, Yamakawa Y, Shizume K, Satoh T, Nohtomi K, Demura H, Akatsu T, Nagata N, Kasahara T, Ohkawa H, Ohsumi K (1993) Passive immunization with anti-parathyroid hormone-related protein monoclonal antibody markedly prolongs survival time of hypercalcemic nude mice bearing transplanted human PTHrP-producing tumors. J Bone Miner Res 8: 849-860.
    • (1993) J Bone Miner Res , vol.8 , pp. 849-860
    • Sato, K.1    Yamakawa, Y.2    Shizume, K.3    Satoh, T.4    Nohtomi, K.5    Demura, H.6    Akatsu, T.7    Nagata, N.8    Kasahara, T.9    Ohkawa, H.10    Ohsumi, K.11
  • 53
    • 0035479861 scopus 로고    scopus 로고
    • Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen
    • Iguchi H, Onuma E, Sato K, Sato K, Ogata E (2001) Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen. Int J Cancer 94: 24-27.
    • (2001) Int J Cancer , vol.94 , pp. 24-27
    • Iguchi, H.1    Onuma, E.2    Sato, K.3    Sato, K.4    Ogata, E.5
  • 54
    • 6444230421 scopus 로고    scopus 로고
    • Generation of a humanized monoclonal antibody against human parathyroid hormone-related protein and its efficacy against humoral hypercalcemia of malignancy
    • Onuma E, Sato K, Saito H, Tsunenari T, Ishii K, Esaki K, Yabuta N, Wakahara Y, Yamada-Okabe H, Ogata E (2004) Generation of a humanized monoclonal antibody against human parathyroid hormone-related protein and its efficacy against humoral hypercalcemia of malignancy. Anticancer Res 24: 2665-2674.
    • (2004) Anticancer Res , vol.24 , pp. 2665-2674
    • Onuma, E.1    Sato, K.2    Saito, H.3    Tsunenari, T.4    Ishii, K.5    Esaki, K.6    Yabuta, N.7    Wakahara, Y.8    Yamada-Okabe, H.9    Ogata, E.10
  • 55
    • 22244464504 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: Possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts
    • Onuma E, Tsunenari T, Saito H, Sato K, Yamada-Okabe H, Ogata E (2005) Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: Possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts. Int J Cancer 116: 471-478.
    • (2005) Int J Cancer , vol.116 , pp. 471-478
    • Onuma, E.1    Tsunenari, T.2    Saito, H.3    Sato, K.4    Yamada-Okabe, H.5    Ogata, E.6
  • 56
    • 33846315463 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides
    • Hashimoto H, Azuma Y, Kawasaki M, Fujihara H, Onuma E, Yamada-Okabe H, Takuwa Y, Ogata E, Ueta Y (2007) Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides. Clin Cancer Res 13: 292-298.
    • (2007) Clin Cancer Res , vol.13 , pp. 292-298
    • Hashimoto, H.1    Azuma, Y.2    Kawasaki, M.3    Fujihara, H.4    Onuma, E.5    Yamada-Okabe, H.6    Takuwa, Y.7    Ogata, E.8    Ueta, Y.9
  • 59
    • 0032915413 scopus 로고    scopus 로고
    • Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting
    • Mizuno TM, Mobbs CV (1999) Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting. Endocrinology 140: 814-817.
    • (1999) Endocrinology , vol.140 , pp. 814-817
    • Mizuno, T.M.1    Mobbs, C.V.2
  • 62
    • 0028829958 scopus 로고
    • Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain
    • Weaver DR, Deeds JD, Lee K, Segre GV. (1995) Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain. Mol Brain Res 28: 296-310.
    • (1995) Mol Brain Res , vol.28 , pp. 296-310
    • Weaver, D.R.1    Deeds, J.D.2    Lee, K.3    Segre, G.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.