-
1
-
-
58149215075
-
Epigenetic regulation and the pathogenesis of systemic lupus erythematosus
-
Pan, Y., and A. H. Sawalha. 2009. Epigenetic regulation and the pathogenesis of systemic lupus erythematosus. Transl. Res. 153: 4-10.
-
(2009)
Transl. Res.
, vol.153
, pp. 4-10
-
-
Pan, Y.1
Sawalha, A.H.2
-
2
-
-
84875751473
-
The role of cytokines in the pathogenesis of systemic lupus erythematosus-from bench to bedside
-
Yap, D. Y., and K. N. Lai. 2013. The role of cytokines in the pathogenesis of systemic lupus erythematosus-from bench to bedside. Nephrology. 18: 243-255.
-
(2013)
Nephrology.
, vol.18
, pp. 243-255
-
-
Yap, D.Y.1
Lai, K.N.2
-
3
-
-
84867197977
-
TH17 cells in autoimmunity and immunodeficiency: Protective or pathogenic?
-
Marwaha, A. K., N. J. Leung, A. N. McMurchy, and M. K. Levings. 2012. TH17 cells in autoimmunity and immunodeficiency: protective or pathogenic? Front. Immunol. 3: 129.
-
(2012)
Front. Immunol.
, vol.3
, pp. 129
-
-
Marwaha, A.K.1
Leung, N.J.2
McMurchy, A.N.3
Levings, M.K.4
-
4
-
-
40649126762
-
The inflammatory Th 17 subset in immunity against self and non-self antigens
-
Jin, D., L. Zhang, J. Zheng, and Y. Zhao. 2008. The inflammatory Th 17 subset in immunity against self and non-self antigens. Autoimmunity. 41: 154-162.
-
(2008)
Autoimmunity.
, vol.41
, pp. 154-162
-
-
Jin, D.1
Zhang, L.2
Zheng, J.3
Zhao, Y.4
-
7
-
-
84867021009
-
Brodalumab and ixekizumab, antiinterleukin-17-receptor antibodies for psoriasis: A critical appraisal
-
discussion 714-715
-
Spuls, P. I., and L. Hooft. 2012. Brodalumab and ixekizumab, antiinterleukin-17-receptor antibodies for psoriasis: a critical appraisal. Br. J. Dermatol. 167: 710-713; discussion 714-715.
-
(2012)
Br. J. Dermatol.
, vol.167
, pp. 710-713
-
-
Spuls, P.I.1
Hooft, L.2
-
8
-
-
84877603562
-
Efficacy and safety of secukinumab in patients with rheumatoid arthritis: A phase II, dose-finding, double-blind, randomised, placebo controlled study
-
Genovese, M. C., P. Durez, H. B. Richards, et al. 2013. Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study. Ann. Rheum. Dis. 72: 863-869.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 863-869
-
-
Genovese, M.C.1
Durez, P.2
Richards, H.B.3
-
9
-
-
84887992906
-
Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: A randomised, double-blind, placebo-controlled trial
-
Baeten, D., X. Baraliakos, J. Braun, et al. 2013. Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial. Lancet. 382: 1705-1713.
-
(2013)
Lancet.
, vol.382
, pp. 1705-1713
-
-
Baeten, D.1
Baraliakos, X.2
Braun, J.3
-
10
-
-
0027215897
-
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
-
Rouvier, E., M. F. Luciani, M. G. Mattei, et al. 1993. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 150: 5445-5456.
-
(1993)
J. Immunol.
, vol.150
, pp. 5445-5456
-
-
Rouvier, E.1
Luciani, M.F.2
Mattei, M.G.3
-
11
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
Kolls, J. K., and A. Linden. 2004. Interleukin-17 family members and inflammation. Immunity. 21: 467-476.
-
(2004)
Immunity.
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Linden, A.2
-
12
-
-
0031282513
-
Molecular characterization of the human interleukin (IL)-17 receptor
-
Yao, Z., M. K. Spriggs, J. M. Derry, et al. 1997. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine. 9: 794-800.
-
(1997)
Cytokine.
, vol.9
, pp. 794-800
-
-
Yao, Z.1
Spriggs, M.K.2
Derry, J.M.3
-
13
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., N. Ghilardi, M. H. Xie, et al. 2003. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278: 1910-1914.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
-
14
-
-
0028858556
-
Human IL-17: A novel cytokine derived from T cells
-
Yao, Z., S. L. Painter, W. C. Fanslow, et al. 1995. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155: 5483-5486.
-
(1995)
J. Immunol.
, vol.155
, pp. 5483-5486
-
-
Yao, Z.1
Painter, S.L.2
Fanslow, W.C.3
-
15
-
-
66149120713
-
Th17 cells in rheumatoid arthritis and systemic lupus erythematosus
-
Pernis, A. B. 2009. Th17 cells in rheumatoid arthritis and systemic lupus erythematosus. J. Intern. Med. 265: 644-652.
-
(2009)
J. Intern. Med.
, vol.265
, pp. 644-652
-
-
Pernis, A.B.1
-
16
-
-
0033758344
-
Increased interleukin-17 production in patients with systemic sclerosis
-
Kurasawa, K., K. Hirose, H. Sano, et al. 2000. Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum. 43: 2455-2463.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2455-2463
-
-
Kurasawa, K.1
Hirose, K.2
Sano, H.3
-
17
-
-
84938079964
-
The role of interleukin-17A in psoriatic disease
-
Adami, S., A. Cavani, F. Rossi, and G. Girolomoni. 2014. The role of interleukin-17A in psoriatic disease. BioDrugs: Clin. Immunother. Biopharm. Gene Ther. 28: 487-497.
-
(2014)
BioDrugs: Clin. Immunother. Biopharm. Gene Ther.
, vol.28
, pp. 487-497
-
-
Adami, S.1
Cavani, A.2
Rossi, F.3
Girolomoni, G.4
-
18
-
-
46749151286
-
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
-
Nurieva, R. I., Y. Chung, D. Hwang, et al. 2008. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 29: 138-149.
-
(2008)
Immunity.
, vol.29
, pp. 138-149
-
-
Nurieva, R.I.1
Chung, Y.2
Hwang, D.3
-
19
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7: 145-173.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
20
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot, J. D., and A. Y. Rudensky. 2005. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol. 6: 331-337.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
21
-
-
27544490377
-
Interleukin 17-producing CD4+effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington, L. E., R. D. Hatton, P. R. Mangan, et al. 2005. Interleukin 17-producing CD4+effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6: 1123-1132.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
22
-
-
39449087338
-
Th17 cells: Effector T cells with inflammatory properties
-
Korn, T., M. Oukka, V. Kuchroo, and E. Bettelli. 2007. Th17 cells: effector T cells with inflammatory properties. Semin. Immunol. 19: 362-371.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 362-371
-
-
Korn, T.1
Oukka, M.2
Kuchroo, V.3
Bettelli, E.4
-
23
-
-
58849162766
-
Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
-
Crispin, J. C., M. Oukka, G. Bayliss, et al. 2008. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J. Immunol. 181: 8761-8766.
-
(2008)
J. Immunol.
, vol.181
, pp. 8761-8766
-
-
Crispin, J.C.1
Oukka, M.2
Bayliss, G.3
-
24
-
-
84859784038
-
Th17 cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues
-
Henriques, A., L. Ines, M. L. Pais, et al. 2012. Th17 cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues. Clin. Rheumatol. 31: 483-491.
-
(2012)
Clin. Rheumatol.
, vol.31
, pp. 483-491
-
-
Henriques, A.1
Ines, L.2
Pais, M.L.3
-
25
-
-
80155211500
-
Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus
-
Yu, B., M. Guan, Y. Peng, et al. 2011. Copy number variations of interleukin-17F, interleukin-21, and interleukin-22 are associated with systemic lupus erythematosus. Arthritis Rheum. 63: 3487-3492.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3487-3492
-
-
Yu, B.1
Guan, M.2
Peng, Y.3
-
27
-
-
84865068306
-
Gene expression of cytokines (TNF-alpha, IFN-gamma), serum profiles of IL-17 and IL-23 in paediatric systemic lupus erythematosus
-
Rana, A., R. W. Minz, R. Aggarwal, et al. 2012. Gene expression of cytokines (TNF-alpha, IFN-gamma), serum profiles of IL-17 and IL-23 in paediatric systemic lupus erythematosus. Lupus. 21: 1105-1112.
-
(2012)
Lupus.
, vol.21
, pp. 1105-1112
-
-
Rana, A.1
Minz, R.W.2
Aggarwal, R.3
-
28
-
-
79960187365
-
High levels of maternal serum IL-17 and activin A in pregnant women affected by systemic lupus erythematosus
-
Torricelli, M., F. Bellisai, R. Novembri, et al. 2011. High levels of maternal serum IL-17 and activin A in pregnant women affected by systemic lupus erythematosus. Am. J. Reprod. Immunol. 66: 84-89.
-
(2011)
Am. J. Reprod. Immunol.
, vol.66
, pp. 84-89
-
-
Torricelli, M.1
Bellisai, F.2
Novembri, R.3
-
29
-
-
77953536871
-
Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity
-
Chen, X. Q., Y. C. Yu, H. H. Deng, et al. 2010. Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity. J. Clin. Immunol. 30: 221-225.
-
(2010)
J. Clin. Immunol.
, vol.30
, pp. 221-225
-
-
Chen, X.Q.1
Yu, Y.C.2
Deng, H.H.3
-
30
-
-
84892386145
-
The proinflammatory potential of T cells in juvenile-onset systemic lupus erythematosus
-
Ballantine, L. E., J. Ong, A. Midgley, et al. 2014. The proinflammatory potential of T cells in juvenile-onset systemic lupus erythematosus. Pediatr. Rheumatol. Online J. 12: 4.
-
(2014)
Pediatr. Rheumatol. Online J.
, vol.12
, pp. 4
-
-
Ballantine, L.E.1
Ong, J.2
Midgley, A.3
-
31
-
-
77954795855
-
Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus
-
Dolff, S., D. Quandt, B. Wilde, et al. 2010. Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus. Arthritis Res. Ther. 12: R150.
-
(2010)
Arthritis Res. Ther.
, vol.12
, pp. R150
-
-
Dolff, S.1
Quandt, D.2
Wilde, B.3
-
32
-
-
84882529537
-
Clinical associations of serum interleukin-17 in systemic lupus erythematosus
-
Vincent, F. B., M. Northcott, A. Hoi, et al. 2013. Clinical associations of serum interleukin-17 in systemic lupus erythematosus. Arthritis Res. Ther. 15: R97.
-
(2013)
Arthritis Res. Ther.
, vol.15
, pp. R97
-
-
Vincent, F.B.1
Northcott, M.2
Hoi, A.3
-
33
-
-
77957867731
-
The relation of interleukin 17 (IL-17) and IL-23 to Th1/Th2 cytokines and disease activity in systemic lupus erythematosus
-
Mok, M. Y., H. J. Wu, Y. Lo, and C. S. Lau. 2010. The relation of interleukin 17 (IL-17) and IL-23 to Th1/Th2 cytokines and disease activity in systemic lupus erythematosus. J. Rheumatol. 37: 2046-2052.
-
(2010)
J. Rheumatol.
, vol.37
, pp. 2046-2052
-
-
Mok, M.Y.1
Wu, H.J.2
Lo, Y.3
Lau, C.S.4
-
34
-
-
84868593854
-
A murine autoimmune model of rheumatoid arthritis and systemic lupus erythematosus associated with deregulated production of IL-17 and IL-21
-
Biswas, P. S., K. Kang, S. Gupta, et al. 2012. A murine autoimmune model of rheumatoid arthritis and systemic lupus erythematosus associated with deregulated production of IL-17 and IL-21. Methods Mol. Biol. 900: 233-251.
-
(2012)
Methods Mol. Biol.
, vol.900
, pp. 233-251
-
-
Biswas, P.S.1
Kang, K.2
Gupta, S.3
-
35
-
-
84874611415
-
Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA
-
Wen, Z., L. Xu, W. Xu, et al. 2013. Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA. PLoS One. 8: e58161.
-
(2013)
PLoS One.
, vol.8
-
-
Wen, Z.1
Xu, L.2
Xu, W.3
-
36
-
-
33745297345
-
Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
-
Toy, D., D. Kugler, M. Wolfson, et al. 2006. Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177: 36-39.
-
(2006)
J. Immunol.
, vol.177
, pp. 36-39
-
-
Toy, D.1
Kugler, D.2
Wolfson, M.3
-
37
-
-
38949155203
-
Regulation of IL-17 production in human lymphocytes
-
Chen, Z., and J. J. O'Shea. 2008. Regulation of IL-17 production in human lymphocytes. Cytokine. 41: 71-78.
-
(2008)
Cytokine.
, vol.41
, pp. 71-78
-
-
Chen, Z.1
O'Shea, J.J.2
-
38
-
-
84878073363
-
Correlations between concentrations of interleukin (IL)-17A, IL-17B and IL-17F, and endothelial cells and proangiogenic cytokines in systemic lupus erythematosus patients
-
Robak, E., L. Kulczycka-Siennicka, Z. Gerlicz, et al. 2013. Correlations between concentrations of interleukin (IL)-17A, IL-17B and IL-17F, and endothelial cells and proangiogenic cytokines in systemic lupus erythematosus patients. Eur. Cytokine Network. 24: 60-68.
-
(2013)
Eur. Cytokine Network.
, vol.24
, pp. 60-68
-
-
Robak, E.1
Kulczycka-Siennicka, L.2
Gerlicz, Z.3
-
40
-
-
84856880805
-
CAMPresponsive element modulator alpha (CREMalpha) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE)
-
Hedrich, C. M., T. Rauen, K. Kis-Toth, et al. 2012. cAMPresponsive element modulator alpha (CREMalpha) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE). J. Biol. Chem. 287: 4715-4725.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 4715-4725
-
-
Hedrich, C.M.1
Rauen, T.2
Kis-Toth, K.3
-
41
-
-
84867755386
-
The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis
-
Chen, D. Y., Y. M. Chen, M. C. Wen, et al. 2012. The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis. Lupus. 21: 1385-1396.
-
(2012)
Lupus.
, vol.21
, pp. 1385-1396
-
-
Chen, D.Y.1
Chen, Y.M.2
Wen, M.C.3
-
42
-
-
70749113527
-
Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis
-
Wang, Y., S. Ito, Y. Chino, et al. 2010. Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis. Clin. Exp. Immunol. 159: 1-10.
-
(2010)
Clin. Exp. Immunol.
, vol.159
, pp. 1-10
-
-
Wang, Y.1
Ito, S.2
Chino, Y.3
-
43
-
-
77951250725
-
Intrathecal cytokine and chemokine profiling in neuropsychiatric lupus or lupus complicated with central nervous system infection
-
Lu, X. Y., C. Q. Zhu, J. Qian, et al. 2010. Intrathecal cytokine and chemokine profiling in neuropsychiatric lupus or lupus complicated with central nervous system infection. Lupus. 19: 689-695.
-
(2010)
Lupus.
, vol.19
, pp. 689-695
-
-
Lu, X.Y.1
Zhu, C.Q.2
Qian, J.3
-
44
-
-
84863517147
-
Elevated Th17 cells are accompanied by FoxP3+Treg cells decrease in patients with lupus nephritis
-
Xing, Q., B. Wang, H. Su, et al. 2012. Elevated Th17 cells are accompanied by FoxP3+Treg cells decrease in patients with lupus nephritis. Rheumatol. Int. 32: 949-958.
-
(2012)
Rheumatol. Int.
, vol.32
, pp. 949-958
-
-
Xing, Q.1
Wang, B.2
Su, H.3
-
45
-
-
75649142843
-
The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus
-
Kwan, B. C., L. S. Tam, K. B. Lai, et al. 2009. The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus. Rheumatology. 48: 1491-1497.
-
(2009)
Rheumatology.
, vol.48
, pp. 1491-1497
-
-
Kwan, B.C.1
Tam, L.S.2
Lai, K.B.3
-
46
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung, Y., S. H. Chang, G. J. Martinez, et al. 2009. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity. 30: 576-587.
-
(2009)
Immunity.
, vol.30
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
-
47
-
-
42649115767
-
TH17 cells in development: An updated view of their molecular identity and genetic programming
-
Dong, C. 2008. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 8: 337-348.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 337-348
-
-
Dong, C.1
-
48
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factorbeta and induction of the nuclear receptor RORgammat
-
Manel, N., D. Unutmaz, and D. R. Littman. 2008. The differentiation of human T(H)-17 cells requires transforming growth factorbeta and induction of the nuclear receptor RORgammat. Nat. Immunol. 9: 641-649.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
49
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S. J., M. A. Meraz, J. M. White, et al. 1998. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell. 93: 373-383.
-
(1998)
Cell.
, vol.93
, pp. 373-383
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
-
50
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P. C., I. Behrmann, G. Muller-Newen, et al. 1998. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334: 297-314.
-
(1998)
Biochem. J.
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Muller-Newen, G.3
-
51
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
Chen, Z., A. Laurence, Y. Kanno, et al. 2006. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc. Natl. Acad. Sci. USA 103: 8137-8142.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
Laurence, A.2
Kanno, Y.3
-
52
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
Yang, X. O., A. D. Panopoulos, R. Nurieva, et al. 2007. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem. 282: 9358-9363.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
-
53
-
-
35348960243
-
Th17: The third member of the effector T cell trilogy
-
Bettelli, E., T. Korn, and V. K. Kuchroo. 2007. Th17: the third member of the effector T cell trilogy. Curr. Opin. Immunol. 19: 652-657.
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 652-657
-
-
Bettelli, E.1
Korn, T.2
Kuchroo, V.K.3
-
54
-
-
80053173155
-
Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus
-
Dolff, S., W. H. Abdulahad, J. Westra, et al. 2011. Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus. Arthritis Res. Ther. 13: R157.
-
(2011)
Arthritis Res. Ther.
, vol.13
, pp. R157
-
-
Dolff, S.1
Abdulahad, W.H.2
Westra, J.3
-
55
-
-
74649086985
-
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
-
Gulen, M. F., Z. Kang, K. Bulek, et al. 2010. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 32: 54-66.
-
(2010)
Immunity.
, vol.32
, pp. 54-66
-
-
Gulen, M.F.1
Kang, Z.2
Bulek, K.3
-
56
-
-
84863151799
-
Microbiota-induced IL-1beta, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine
-
Shaw, M. H., N. Kamada, Y. G. Kim, and G. Nunez. 2012. Microbiota-induced IL-1beta, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine. J. Exp. Med. 209: 251-258.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 251-258
-
-
Shaw, M.H.1
Kamada, N.2
Kim, Y.G.3
Nunez, G.4
-
57
-
-
84875610850
-
Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells
-
Kurebayashi, Y., S. Nagai, A. Ikejiri, and S. Koyasu. 2013. Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells. Genes Cells: Devot. Mol. Cell. Mech. 18: 247-265.
-
(2013)
Genes Cells: Devot. Mol. Cell. Mech.
, vol.18
, pp. 247-265
-
-
Kurebayashi, Y.1
Nagai, S.2
Ikejiri, A.3
Koyasu, S.4
-
58
-
-
84880028487
-
ERK differentially regulates Th17-and Treg-cell development and contributes to the pathogenesis of colitis
-
Liu, H., S. Yao, S. M. Dann, et al. 2013. ERK differentially regulates Th17-and Treg-cell development and contributes to the pathogenesis of colitis. Eur. J. Immunol. 43: 1716-1726.
-
(2013)
Eur. J. Immunol.
, vol.43
, pp. 1716-1726
-
-
Liu, H.1
Yao, S.2
Dann, S.M.3
-
59
-
-
84861134382
-
PI3K-AktmTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORgamma
-
Kurebayashi, Y., S. Nagai, A. Ikejiri, et al. 2012. PI3K-AktmTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORgamma. Cell. Rep. 1: 360-373.
-
(2012)
Cell. Rep.
, vol.1
, pp. 360-373
-
-
Kurebayashi, Y.1
Nagai, S.2
Ikejiri, A.3
-
60
-
-
84868548958
-
T cell receptor/CARMA1/NF-kappaB signaling controls T-helper (Th) 17 differentiation
-
Molinero, L. L., A. Cubre, C. Mora-Solano, et al. 2012. T cell receptor/CARMA1/NF-kappaB signaling controls T-helper (Th) 17 differentiation. Proc. Natl. Acad. Sci. USA 109: 18529-18534.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 18529-18534
-
-
Molinero, L.L.1
Cubre, A.2
Mora-Solano, C.3
-
61
-
-
79251589323
-
Profiling of CD4+T cells with epigenetic immune lineage analysis
-
Janson, P. C., L. B. Linton, E. A. Bergman, et al. 2011. Profiling of CD4+T cells with epigenetic immune lineage analysis. J. Immunol. 186: 92-102.
-
(2011)
J. Immunol.
, vol.186
, pp. 92-102
-
-
Janson, P.C.1
Linton, L.B.2
Bergman, E.A.3
-
62
-
-
83355166923
-
CAMPresponsive element modulator (CREM)alpha protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus
-
Rauen, T., C. M. Hedrich, Y. T. Juang, et al. 2011. cAMPresponsive element modulator (CREM)alpha protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus. J. Biol. Chem. 286: 43437-43446.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43437-43446
-
-
Rauen, T.1
Hedrich, C.M.2
Juang, Y.T.3
-
63
-
-
84861473517
-
Plasticity of DNA methylation in mouse T cell activation and differentiation
-
Li, Y., G. Chen, L. Ma, et al. 2012. Plasticity of DNA methylation in mouse T cell activation and differentiation. BMC Mol. Biol. 13: 16.
-
(2012)
BMC Mol. Biol.
, vol.13
, pp. 16
-
-
Li, Y.1
Chen, G.2
Ma, L.3
-
64
-
-
34147138648
-
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
-
Akimzhanov, A. M., X. O. Yang, and C. Dong. 2007. Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J. Biol. Chem. 282: 5969-5972.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 5969-5972
-
-
Akimzhanov, A.M.1
Yang, X.O.2
Dong, C.3
-
65
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+T cells
-
Wei, G., L. Wei, J. Zhu, et al. 2009. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+T cells. Immunity. 30: 155-167.
-
(2009)
Immunity.
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
-
66
-
-
84867351076
-
CAMP response element modulator alpha controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus
-
Hedrich, C. M., J. C. Crispin, T. Rauen, et al. 2012. cAMP response element modulator alpha controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus. Proc. Natl. Acad. Sci. USA. 109: 16606-16611.
-
(2012)
Proc. Natl. Acad. Sci. USA.
, vol.109
, pp. 16606-16611
-
-
Hedrich, C.M.1
Crispin, J.C.2
Rauen, T.3
-
67
-
-
84899760423
-
CaMK4-dependent activation of AKT/mTOR and CREM-alpha underlies autoimmunity-associated Th17 imbalance
-
Koga, T., C. M. Hedrich, M. Mizui, et al. 2014. CaMK4-dependent activation of AKT/mTOR and CREM-alpha underlies autoimmunity-associated Th17 imbalance. J. Clin. Investig. 124: 2234-2245.
-
(2014)
J. Clin. Investig.
, vol.124
, pp. 2234-2245
-
-
Koga, T.1
Hedrich, C.M.2
Mizui, M.3
-
68
-
-
84884197375
-
Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling
-
Apostolidis, S. A., T. Rauen, C. M. Hedrich, et al. 2013. Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling. J. Biol. Chem. 288: 26775-26784.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 26775-26784
-
-
Apostolidis, S.A.1
Rauen, T.2
Hedrich, C.M.3
-
69
-
-
84878579250
-
Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus
-
Isgro, J., S. Gupta, E. Jacek, et al. 2013. Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus. Arthritis Rheum. 65: 1592-1602.
-
(2013)
Arthritis Rheum.
, vol.65
, pp. 1592-1602
-
-
Isgro, J.1
Gupta, S.2
Jacek, E.3
-
70
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
Weaver, C. T., R. D. Hatton, P. R. Mangan, and L. E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
71
-
-
0033765333
-
Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells
-
Woltman, A. M., S. de Haij, J. G. Boonstra, et al. 2000. Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. J. Am. Soc. Nephrol.: JASN. 11: 2044-2055.
-
(2000)
J. Am. Soc. Nephrol.: JASN.
, vol.11
, pp. 2044-2055
-
-
Woltman, A.M.1
De Haij, S.2
Boonstra, J.G.3
-
72
-
-
51349111163
-
An overview of IL-17 function and signaling
-
Gaffen, S. L. 2008. An overview of IL-17 function and signaling. Cytokine. 43: 402-407.
-
(2008)
Cytokine.
, vol.43
, pp. 402-407
-
-
Gaffen, S.L.1
-
73
-
-
75949102667
-
Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease
-
Onishi, R. M., and S. L. Gaffen. 2010. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology. 129: 311-321.
-
(2010)
Immunology.
, vol.129
, pp. 311-321
-
-
Onishi, R.M.1
Gaffen, S.L.2
-
74
-
-
0038281377
-
IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients
-
Dong, G., R. Ye, W. Shi, et al. 2003. IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients. Chin. Med. J. 116: 543-548.
-
(2003)
Chin. Med. J.
, vol.116
, pp. 543-548
-
-
Dong, G.1
Ye, R.2
Shi, W.3
-
75
-
-
67649197343
-
Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
-
Doreau, A., A. Belot, J. Bastid, et al. 2009. Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat. Immunol. 10: 778-785.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 778-785
-
-
Doreau, A.1
Belot, A.2
Bastid, J.3
-
76
-
-
77349093568
-
B-cell biology and related therapies in systemic lupus erythematosus
-
viii-ix
-
Ahmed, S., and J. H. Anolik. 2010. B-cell biology and related therapies in systemic lupus erythematosus. Rheum. Dis. Clin. N. Am. 36: 109-130, viii-ix.
-
(2010)
Rheum. Dis. Clin. N. Am.
, vol.36
, pp. 109-130
-
-
Ahmed, S.1
Anolik, J.H.2
-
77
-
-
0032939560
-
IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha
-
Albanesi, C., A. Cavani, and G. Girolomoni. 1999. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J. Immunol. 162: 494-502.
-
(1999)
J. Immunol.
, vol.162
, pp. 494-502
-
-
Albanesi, C.1
Cavani, A.2
Girolomoni, G.3
-
78
-
-
0034193959
-
Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis
-
Schwarzenberger, P., W. Huang, P. Ye, et al. 2000. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J. Immunol. 164: 4783-4789.
-
(2000)
J. Immunol.
, vol.164
, pp. 4783-4789
-
-
Schwarzenberger, P.1
Huang, W.2
Ye, P.3
-
79
-
-
44949195816
-
T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis
-
Cohen, R. A., G. Bayliss, J. C. Crispin, et al. 2008. T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis. Clin. Immunol. 128: 1-7.
-
(2008)
Clin. Immunol.
, vol.128
, pp. 1-7
-
-
Cohen, R.A.1
Bayliss, G.2
Crispin, J.C.3
-
80
-
-
66049151440
-
Th17 and natural Treg cell population dynamics in systemic lupus erythematosus
-
Yang, J., Y. Chu, X. Yang, et al. 2009. Th17 and natural Treg cell population dynamics in systemic lupus erythematosus. Arthritis Rheum. 60: 1472-1483.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1472-1483
-
-
Yang, J.1
Chu, Y.2
Yang, X.3
-
81
-
-
84887350775
-
Inhibition of IL-17 as a pharmacological approach for IBD
-
Fitzpatrick, L. R. 2013. Inhibition of IL-17 as a pharmacological approach for IBD. Int. Rev. Immunol. 32: 544-555.
-
(2013)
Int. Rev. Immunol.
, vol.32
, pp. 544-555
-
-
Fitzpatrick, L.R.1
-
82
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C. L., Y. Chen, W. M. Blumenschein, et al. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201: 233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
-
83
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato, K., A. Suematsu, K. Okamoto, et al. 2006. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203: 2673-2682.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
-
84
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae, S., A. Nambu, K. Sudo, and Y. Iwakura. 2003. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 171: 6173-6177.
-
(2003)
J. Immunol.
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
85
-
-
84929718360
-
Interleukin-17 is a critical target for the treatment of ankylosing enthesitis and psoriasis-like dermatitis in mice
-
[Epub ahead of print]
-
Ebihara, S., F. Date, Y. Dong, and M. Ono. 2014. Interleukin-17 is a critical target for the treatment of ankylosing enthesitis and psoriasis-like dermatitis in mice. Autoimmunity. 1-8. [Epub ahead of print]. doi: 10.3109/08916934.2014.976630.
-
(2014)
Autoimmunity.
, pp. 1-8
-
-
Ebihara, S.1
Date, F.2
Dong, Y.3
Ono, M.4
-
86
-
-
79953073305
-
Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis
-
Chao, C. C., S. J. Chen, I. E. Adamopoulos, et al. 2011. Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis. Autoimmunity. 44: 243-252.
-
(2011)
Autoimmunity.
, vol.44
, pp. 243-252
-
-
Chao, C.C.1
Chen, S.J.2
Adamopoulos, I.E.3
-
87
-
-
84873124241
-
Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled phase II dose-ranging study
-
Papp, K. A., R. G. Langley, B. Sigurgeirsson, et al. 2013. Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study. Br. J. Dermatol. 168: 412-421.
-
(2013)
Br. J. Dermatol.
, vol.168
, pp. 412-421
-
-
Papp, K.A.1
Langley, R.G.2
Sigurgeirsson, B.3
-
88
-
-
84873168729
-
Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled, phase II regimen-finding study
-
Rich, P., B. Sigurgeirsson, D. Thaci, et al. 2013. Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study. Br. J. Dermatol. 168: 402-411.
-
(2013)
Br. J. Dermatol.
, vol.168
, pp. 402-411
-
-
Rich, P.1
Sigurgeirsson, B.2
Thaci, D.3
-
89
-
-
84912024938
-
Secukinumab improves hand, foot and nail lesions in moderate-to-severe plaque psoriasis: Subanalysis of a randomized, double-blind, placebocontrolled, regimen-finding phase 2 trial
-
Paul, C., K. Reich, A. B. Gottlieb, et al. 2014. Secukinumab improves hand, foot and nail lesions in moderate-to-severe plaque psoriasis: subanalysis of a randomized, double-blind, placebocontrolled, regimen-finding phase 2 trial. J. Eur. Acad. Dermatol. Venereol.: JEADV. 28: 1670-1675.
-
(2014)
J. Eur. Acad. Dermatol. Venereol.: JEADV.
, vol.28
, pp. 1670-1675
-
-
Paul, C.1
Reich, K.2
Gottlieb, A.B.3
-
90
-
-
84905862282
-
Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: Subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study
-
Sigurgeirsson, B., L. Kircik, O. Nemoto, et al. 2014. Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study. J. Eur. Acad. Dermatol. Venereol.: JEADV. 28: 1127-1129.
-
(2014)
J. Eur. Acad. Dermatol. Venereol.: JEADV.
, vol.28
, pp. 1127-1129
-
-
Sigurgeirsson, B.1
Kircik, L.2
Nemoto, O.3
-
91
-
-
84891740105
-
Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
-
McInnes, I. B., J. Sieper, J. Braun, et al. 2014. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann. Rheum. Dis. 73: 349-356.
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 349-356
-
-
McInnes, I.B.1
Sieper, J.2
Braun, J.3
-
92
-
-
84903581591
-
Antibodies to watch in 2014: Mid-year update
-
Reichert, J. M. 2014. Antibodies to watch in 2014: mid-year update. mAbs. 6: 799-802.
-
(2014)
MAbs.
, vol.6
, pp. 799-802
-
-
Reichert, J.M.1
-
94
-
-
84897954122
-
Secukinumab treatment in rheumatoid arthritis is associated with incremental benefit in the clinical outcomes and HRQoL improvements that exceed minimally important thresholds
-
Strand, V., M. Kosinski, A. Gnanasakthy, et al. 2014. Secukinumab treatment in rheumatoid arthritis is associated with incremental benefit in the clinical outcomes and HRQoL improvements that exceed minimally important thresholds. Health Qual. Life. Outcomes. 12: 31.
-
(2014)
Health Qual. Life. Outcomes.
, vol.12
, pp. 31
-
-
Strand, V.1
Kosinski, M.2
Gnanasakthy, A.3
-
95
-
-
84895465850
-
One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: Phase II, dose-finding, double-blind, randomized, placebo-controlled study
-
Genovese, M. C., P. Durez, H. B. Richards, et al. 2014. One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study. J. Rheumatol. 41: 414-421.
-
(2014)
J. Rheumatol.
, vol.41
, pp. 414-421
-
-
Genovese, M.C.1
Durez, P.2
Richards, H.B.3
-
96
-
-
84887444732
-
Targeting interleukin-17 in patients with active rheumatoid arthritis: Rationale and clinical potential
-
Kellner, H. 2013. Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential. Ther. Adv. Musculoskelet. Dis. 5: 141-152.
-
(2013)
Ther. Adv. Musculoskelet. Dis.
, vol.5
, pp. 141-152
-
-
Kellner, H.1
-
97
-
-
84879890395
-
Treatment of spondyloarthropathy: The potential for agents other than TNF inhibitors
-
Her, M., and A. Kavanaugh. 2013. Treatment of spondyloarthropathy: the potential for agents other than TNF inhibitors. Curr. Opin. Rheumatol. 25: 455-459.
-
(2013)
Curr. Opin. Rheumatol.
, vol.25
, pp. 455-459
-
-
Her, M.1
Kavanaugh, A.2
-
98
-
-
84874592146
-
Treating multiple sclerosis with monoclonal antibodies: A 2013 update
-
Deiss, A., I. Brecht, A. Haarmann, and M. Buttmann. 2013. Treating multiple sclerosis with monoclonal antibodies: a 2013 update. Expert. Rev. Neurother. 13: 313-335.
-
(2013)
Expert. Rev. Neurother.
, vol.13
, pp. 313-335
-
-
Deiss, A.1
Brecht, I.2
Haarmann, A.3
Buttmann, M.4
-
99
-
-
84875697084
-
Secukinumab in the treatment of noninfectious uveitis: Results of three randomized, controlled clinical trials
-
Dick, A. D., I. Tugal-Tutkun, S. Foster, et al. 2013. Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials. Ophthalmology. 120: 777-787.
-
(2013)
Ophthalmology.
, vol.120
, pp. 777-787
-
-
Dick, A.D.1
Tugal-Tutkun, I.2
Foster, S.3
-
100
-
-
84896314616
-
The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes
-
Elain, G., K. Jeanneau, A. Rutkowska, et al. 2014. The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes. Glia. 62: 725-735.
-
(2014)
Glia.
, vol.62
, pp. 725-735
-
-
Elain, G.1
Jeanneau, K.2
Rutkowska, A.3
-
101
-
-
84902266081
-
Not all monoclonals are created equal-lessons from failed drug trials in Crohn's disease
-
Kaser, A. 2014. Not all monoclonals are created equal-lessons from failed drug trials in Crohn's disease. Best. Pract. Res. Clin. Gastroenterol. 28: 437-449.
-
(2014)
Best. Pract. Res. Clin. Gastroenterol.
, vol.28
, pp. 437-449
-
-
Kaser, A.1
-
102
-
-
84883591833
-
Combined blockade of IL-17A and IL-17F may prevent the development of experimental colitis
-
McLean, L. P., R. K. Cross, and T. Shea-Donohue. 2013. Combined blockade of IL-17A and IL-17F may prevent the development of experimental colitis. Immunotherapy. 5: 923-925.
-
(2013)
Immunotherapy.
, vol.5
, pp. 923-925
-
-
McLean, L.P.1
Cross, R.K.2
Shea-Donohue, T.3
-
103
-
-
84883571248
-
TH17 cell induction and effects of IL-17A and IL-17F blockade in experimental colitis
-
Wedebye Schmidt, E. G., H. L. Larsen, N. N. Kristensen, et al. 2013. TH17 cell induction and effects of IL-17A and IL-17F blockade in experimental colitis. Inflamm. Bowel. Dis. 19: 1567-1576.
-
(2013)
Inflamm. Bowel. Dis.
, vol.19
, pp. 1567-1576
-
-
Wedebye Schmidt, E.G.1
Larsen, H.L.2
Kristensen, N.N.3
-
104
-
-
38349178776
-
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
-
Hsu, H. C., P. Yang, J. Wang, et al. 2008. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat. Immunol. 9: 166-175.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 166-175
-
-
Hsu, H.C.1
Yang, P.2
Wang, J.3
-
105
-
-
59249101944
-
IL-17 producing CD4+T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice
-
Edgerton, C., J. C. Crispin, C. M. Moratz, et al. 2009. IL-17 producing CD4+T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice. Clin. Immunol. 130: 313-321.
-
(2009)
Clin. Immunol.
, vol.130
, pp. 313-321
-
-
Edgerton, C.1
Crispin, J.C.2
Moratz, C.M.3
-
106
-
-
84895107356
-
Pragmatic approaches to therapy for systemic lupus erythematosus
-
Xiong, W., and R. G. Lahita. 2014. Pragmatic approaches to therapy for systemic lupus erythematosus. Nat. Rev. Rheumatol. 10: 97-107.
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 97-107
-
-
Xiong, W.1
Lahita, R.G.2
|