cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 43437-43446

  Rauen, Thomas ^a,b   Hedrich, Christian M ^a   Juang, Yuang Taung ^a   Tenbrock, Klaus ^b   Tsokos, George C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE DISEASE; CHROMATIN IMMUNOPRECIPITATION ASSAY; CHROMATIN STRUCTURE; DNA METHYLATION; DNA METHYLTRANSFERASES; EPIGENETIC ALTERATIONS; EXPRESSION LEVELS; GUANOSINES; HEALTHY CONTROLS; HISTONE DEACETYLASES; HISTONE H3; HYPERACETYLATION; HYPOMETHYLATION; NON-CODING SEQUENCES; PROINFLAMMATORY CYTOKINES; SYSTEMIC LUPUS ERYTHEMATOSUS; T CELLS;

ALKYLATION; DNA; GENES; METHYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELLS;

ADENINE; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; CYTOKINE; CYTOSINE; DNA; DNA METHYLTRANSFERASE; GUANOSINE; HISTONE DEACETYLASE; HISTONE H3; INTERLEUKIN 17; MESSENGER RNA; PHOSPHATE; THYMINE;

ARTICLE; CD4+ T LYMPHOCYTE; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; FEMALE; GENE LOCUS; GENE SEQUENCE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; INFLAMMATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TRANSCRIPTION INITIATION;

CELLS, CULTURED; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CYCLIC AMP RESPONSE ELEMENT MODULATOR; DNA METHYLATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPIGENESIS, GENETIC; FEMALE; HISTONES; HUMANS; INTERLEUKIN-17; LUPUS ERYTHEMATOSUS, SYSTEMIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 83355166923     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.299313     Document Type: Article

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