메뉴 건너뛰기




Volumn 19, Issue 8, 2013, Pages 1567-1576

TH17 cell induction and effects of IL-17A and IL-17F blockade in experimental colitis

Author keywords

Colitis; IL 17A; IL 17F; TH17

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 17F; NEUTRALIZING ANTIBODY;

EID: 84883571248     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0b013e318286fa1c     Document Type: Article
Times cited : (75)

References (61)
  • 1
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham C, Cho JH. Inflammatory bowel disease. N Engl J Med. 2009; 361:2066-2078.
    • (2009) N Engl J Med , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 2
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6:1123-1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 3
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med. 2005;201:233-240.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 4
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005;6: 1133-1141.
    • (2005) Nat Immunol , vol.6 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3
  • 5
    • 55149090692 scopus 로고    scopus 로고
    • Th17 cytokines and mucosal immunity
    • Dubin PJ, Kolls JK. Th17 cytokines and mucosal immunity. Immunol Rev. 2008;226:160-171.
    • (2008) Immunol Rev , vol.226 , pp. 160-171
    • Dubin, P.J.1    Kolls, J.K.2
  • 7
    • 72549107316 scopus 로고    scopus 로고
    • Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
    • Rovedatti L, Kudo T, Biancheri P, et al. Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease. Gut. 2009;58:1629-1636.
    • (2009) Gut , vol.58 , pp. 1629-1636
    • Rovedatti, L.1    Kudo, T.2    Biancheri, P.3
  • 8
    • 59449094473 scopus 로고    scopus 로고
    • T cell transfer model of chronic colitis: Concepts, considerations, and tricks of the trade
    • Ostanin DV, Bao J, Koboziev I, et al. T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade. Am J Physiol Gastrointest Liver Physiol. 2009;296:G135-G146.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Ostanin, D.V.1    Bao, J.2    Koboziev, I.3
  • 9
    • 33750505009 scopus 로고    scopus 로고
    • Interleukin-23 drives innate and T cell-mediated intestinal inflammation
    • Hue S, Ahern P, Buonocore S, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med. 2006;203:2473-2483.
    • (2006) J Exp Med , vol.203 , pp. 2473-2483
    • Hue, S.1    Ahern, P.2    Buonocore, S.3
  • 10
    • 33750530394 scopus 로고    scopus 로고
    • IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
    • Kullberg MC, Jankovic D, Feng CG, et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J Exp Med. 2006;203:2485-2494.
    • (2006) J Exp Med , vol.203 , pp. 2485-2494
    • Kullberg, M.C.1    Jankovic, D.2    Feng, C.G.3
  • 11
    • 36248965294 scopus 로고    scopus 로고
    • TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cellmediated pathology
    • McGeachy MJ, Bak-Jensen KS, Chen Y, et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cellmediated pathology. Nat Immunol. 2007;8:1390-1397.
    • (2007) Nat Immunol , vol.8 , pp. 1390-1397
    • McGeachy, M.J.1    Bak-Jensen, K.S.2    Chen, Y.3
  • 12
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D, Cheung J, Scheerens H, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest. 2006; 116:1310-1316.
    • (2006) J Clin Invest , vol.116 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3
  • 13
    • 59849114998 scopus 로고    scopus 로고
    • RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F
    • Leppkes M, Becker C, Ivanov II, et al. RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology. 2009;136:257-267.
    • (2009) Gastroenterology , vol.136 , pp. 257-267
    • Leppkes, M.1    Becker, C.2    Ivanov, I.I.3
  • 14
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med. 2009;15:1016-1022.
    • (2009) Nat Med , vol.15 , pp. 1016-1022
    • Wu, S.1    Rhee, K.J.2    Albesiano, E.3
  • 15
    • 33646804892 scopus 로고    scopus 로고
    • Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
    • Zhang Z, Zheng M, Bindas J, et al. Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis. 2006;12: 382-388.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 382-388
    • Zhang, Z.1    Zheng, M.2    Bindas, J.3
  • 16
    • 54449102022 scopus 로고    scopus 로고
    • Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice
    • Ito R, Kita M, Shin-Ya M, et al. Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice. Biochem Biophys Res Commun. 2008;377:12-16.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 12-16
    • Ito, R.1    Kita, M.2    Shin-Ya, M.3
  • 17
    • 65749091607 scopus 로고    scopus 로고
    • A protective function for interleukin 17A in T cell-mediated intestinal inflammation
    • O'Connor W Jr, Kamanaka M, Booth CJ, et al. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol. 2009;10:603-609.
    • (2009) Nat Immunol , vol.10 , pp. 603-609
    • O'Connor Jr., W.1    Kamanaka, M.2    Booth, C.J.3
  • 18
    • 43549110961 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by IL-17F
    • Yang XO, Chang SH, Park H, et al. Regulation of inflammatory responses by IL-17F. J Exp Med. 2008;205:1063-1075.
    • (2008) J Exp Med , vol.205 , pp. 1063-1075
    • Yang, X.O.1    Chang, S.H.2    Park, H.3
  • 19
    • 11144286392 scopus 로고    scopus 로고
    • Interleukin-17/interleukin-17 receptormediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection
    • Kelly MN, Kolls JK, Happel K, et al. Interleukin-17/interleukin-17 receptormediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun. 2005;73:617-621.
    • (2005) Infect Immun , vol.73 , pp. 617-621
    • Kelly, M.N.1    Kolls, J.K.2    Happel, K.3
  • 20
    • 41849142985 scopus 로고    scopus 로고
    • Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut
    • Rafatellu M, Santos RL, Verhoeven DE, et al. Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med. 2008;14:421-428.
    • (2008) Nat Med , vol.14 , pp. 421-428
    • Rafatellu, M.1    Santos, R.L.2    Verhoeven, D.E.3
  • 21
    • 0034128634 scopus 로고    scopus 로고
    • Claudins regulate the intestinal barrier in response to immune mediators
    • Kinugasa T, Sakaguchi T, Gu X, et al. Claudins regulate the intestinal barrier in response to immune mediators. Gastroenterology. 2000;118:1001-1011.
    • (2000) Gastroenterology , vol.118 , pp. 1001-1011
    • Kinugasa, T.1    Sakaguchi, T.2    Gu, X.3
  • 22
    • 0035888025 scopus 로고    scopus 로고
    • Identification of a novel cytokine, ML-1, and its expression in subjects with asthma
    • Kawaguchi M, Onuchic LF, Li XD, et al. Identification of a novel cytokine, ML-1, and its expression in subjects with asthma. J Immunol. 2001; 167:4430-4435.
    • (2001) J Immunol , vol.167 , pp. 4430-4435
    • Kawaguchi, M.1    Onuchic, L.F.2    Li, X.D.3
  • 23
    • 77954143695 scopus 로고    scopus 로고
    • Innate IL-17-producing cells: The sentinels of the immune system
    • Cua DJ, Tato CM. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol. 2010;10:479-489.
    • (2010) Nat Rev Immunol , vol.10 , pp. 479-489
    • Cua, D.J.1    Tato, C.M.2
  • 24
    • 84868680312 scopus 로고    scopus 로고
    • Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: Unexpected results of a randomised, double-blind placebo-controlled trial
    • Hueber W, Sands BE, Lewitzky S, et al. Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut. 2012;61: 1693-1700.
    • (2012) Gut , vol.61 , pp. 1693-1700
    • Hueber, W.1    Sands, B.E.2    Lewitzky, S.3
  • 25
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, et al. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol. 2007; 25:821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3
  • 26
    • 21244455537 scopus 로고    scopus 로고
    • Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis
    • McAllister F, Henry A, Kreindler JL, et al. Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol. 2005;175:404-412.
    • (2005) J Immunol , vol.175 , pp. 404-412
    • McAllister, F.1    Henry, A.2    Kreindler, J.L.3
  • 27
    • 42449084096 scopus 로고    scopus 로고
    • Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p. His161-Arg polymorphism in IBD
    • Seiderer J, Elben I, Diegelmann J, et al. Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p. His161-Arg polymorphism in IBD. Inflamm Bowel Dis. 2008;14:437-445.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 437-445
    • Seiderer, J.1    Elben, I.2    Diegelmann, J.3
  • 28
    • 9944229536 scopus 로고    scopus 로고
    • Characterization of T-regulatory cells, induced by immature dendritic cells, which inhibit enteroantigen-reactive colitisinducing T-cell responses in vitro and in vivo
    • Gad M, Kristensen NN, Kury E, et al. Characterization of T-regulatory cells, induced by immature dendritic cells, which inhibit enteroantigen-reactive colitisinducing T-cell responses in vitro and in vivo. Immunology. 2004;113:499-508.
    • (2004) Immunology , vol.113 , pp. 499-508
    • Gad, M.1    Kristensen, N.N.2    Kury, E.3
  • 29
    • 33745524196 scopus 로고    scopus 로고
    • Chemokines involved in protection from colitis by CD4+CD25+ regulatory T cells
    • Kristensen NN, Brudzewsky D, Gad M, et al. Chemokines involved in protection from colitis by CD4+CD25+ regulatory T cells. Inflamm Bowel Dis. 2006;12:612-618.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 612-618
    • Kristensen, N.N.1    Brudzewsky, D.2    Gad, M.3
  • 30
    • 77955890952 scopus 로고    scopus 로고
    • Interleukin-23 drives intestinal inflammation through direct activity on T cells
    • Ahern PP, Schiering C, Buonocore S, et al. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity. 2010;33:279-288.
    • (2010) Immunity , vol.33 , pp. 279-288
    • Ahern, P.P.1    Schiering, C.2    Buonocore, S.3
  • 31
    • 34547734621 scopus 로고    scopus 로고
    • Phenotypic and functional features of human Th17 cells
    • Annunziato F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17 cells. J Exp Med. 2007;204:1849-1861.
    • (2007) J Exp Med , vol.204 , pp. 1849-1861
    • Annunziato, F.1    Cosmi, L.2    Santarlasci, V.3
  • 32
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • Cosmi L, De Palma R, Santarlasci V, et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med. 2008;205:1903-1916.
    • (2008) J Exp Med , vol.205 , pp. 1903-1916
    • Cosmi, L.1    De Palma, R.2    Santarlasci, V.3
  • 33
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn disease
    • Lodes MJ, Cong Y, Elson CO, et al. Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest. 2004;113:1296-1306.
    • (2004) J Clin Invest , vol.113 , pp. 1296-1306
    • Lodes, M.J.1    Cong, Y.2    Elson, C.O.3
  • 34
    • 35349019357 scopus 로고    scopus 로고
    • Isolation of flagellated bacteria implicated in Crohn's disease
    • Duck LW, Walter MR, Novak J, et al. Isolation of flagellated bacteria implicated in Crohn's disease. Inflamm Bowel Dis. 2007;13:1191-1201.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1191-1201
    • Duck, L.W.1    Walter, M.R.2    Novak, J.3
  • 35
    • 0025339265 scopus 로고
    • T cell antigen receptor v gene usage. Increases in v beta 8+ T cells in Crohn's disease
    • Posnett DN, Schmelkin I, Burton DA, et al. T cell antigen receptor V gene usage. Increases in V beta 8+ T cells in Crohn's disease. J Clin Invest. 1990;85:1770-1776.
    • (1990) J Clin Invest , vol.85 , pp. 1770-1776
    • Posnett, D.N.1    Schmelkin, I.2    Burton, D.A.3
  • 36
    • 0029965229 scopus 로고    scopus 로고
    • Preferential activation of CD4+V beta 5.2/5.3+ intestinal intraepithelial lymphocytes in the inflamed lesions of Crohn's disease
    • Watanabe M, Hayashi A, Hosoda Y, et al. Preferential activation of CD4+V beta 5.2/5.3+ intestinal intraepithelial lymphocytes in the inflamed lesions of Crohn's disease. Clin Immunol Immunopathol. 1996;78:130-139.
    • (1996) Clin Immunol Immunopathol , vol.78 , pp. 130-139
    • Watanabe, M.1    Hayashi, A.2    Hosoda, Y.3
  • 37
    • 65549098640 scopus 로고    scopus 로고
    • CD4 T-cell differentiation and inflammatory bowel disease
    • Zenewicz LA, Antov A, Flavell RA. CD4 T-cell differentiation and inflammatory bowel disease. Trends Mol Med. 2009;15:199-207.
    • (2009) Trends Mol Med , vol.15 , pp. 199-207
    • Zenewicz, L.A.1    Antov, A.2    Flavell, R.A.3
  • 38
    • 44849105008 scopus 로고    scopus 로고
    • Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection
    • Moxham VF, Karegli J, Phillips RE, et al. Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol. 2008;180:3910-3918.
    • (2008) J Immunol , vol.180 , pp. 3910-3918
    • Moxham, V.F.1    Karegli, J.2    Phillips, R.E.3
  • 39
    • 0031794558 scopus 로고    scopus 로고
    • Proliferation and apoptosis of lamina propria CD4+ T cells from scid mice with inflammatory bowel disease
    • Bregenholt S, Reimann J, Claesson MH. Proliferation and apoptosis of lamina propria CD4+ T cells from scid mice with inflammatory bowel disease. Eur J Immunol. 1998;28:3655-3663.
    • (1998) Eur J Immunol , vol.28 , pp. 3655-3663
    • Bregenholt, S.1    Reimann, J.2    Claesson, M.H.3
  • 40
    • 25444525391 scopus 로고    scopus 로고
    • The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation
    • Fortner KA, Budd RC. The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation. J Immunol. 2005;175:4374-4382.
    • (2005) J Immunol , vol.175 , pp. 4374-4382
    • Fortner, K.A.1    Budd, R.C.2
  • 41
    • 73349127028 scopus 로고    scopus 로고
    • Unlike Th1, Th17 cells mediate sustained autoimmune inflammation and are highly resistant to restimulation-induced cell death
    • Shi G, Ramaswamy M, Vistica BP, et al. Unlike Th1, Th17 cells mediate sustained autoimmune inflammation and are highly resistant to restimulation-induced cell death. J Immunol. 2009;183:7547-7556.
    • (2009) J Immunol , vol.183 , pp. 7547-7556
    • Shi, G.1    Ramaswamy, M.2    Vistica, B.P.3
  • 42
    • 64849103287 scopus 로고    scopus 로고
    • Cutting edge: In vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts
    • Nurieva R, Yang XO, Chung Y, et al. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol. 2009:182:2565-2568.
    • (2009) J Immunol , vol.182 , pp. 2565-2568
    • Nurieva, R.1    Yang, X.O.2    Chung, Y.3
  • 43
    • 77953486362 scopus 로고    scopus 로고
    • Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis
    • Feng T, Wang L, Schoeb TR, et al. Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis. J Exp Med. 2010;207:1321-1332.
    • (2010) J Exp Med , vol.207 , pp. 1321-1332
    • Feng, T.1    Wang, L.2    Schoeb, T.R.3
  • 44
    • 20444441016 scopus 로고    scopus 로고
    • Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease
    • Targan SR, Landers CJ, Yang H, et al. Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology. 2005;128:2020-2028.
    • (2005) Gastroenterology , vol.128 , pp. 2020-2028
    • Targan, S.R.1    Landers, C.J.2    Yang, H.3
  • 45
    • 0030267661 scopus 로고    scopus 로고
    • Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease
    • Probert CS, Chott A, Turner JR, et al. Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease. J Immunol. 1996;157:3183-3191.
    • (1996) J Immunol , vol.157 , pp. 3183-3191
    • Probert, C.S.1    Chott, A.2    Turner, J.R.3
  • 46
    • 33746161021 scopus 로고    scopus 로고
    • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells
    • Uematsu S, Jang MH, Chevrier N, et al. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat Immunol. 2006;7:868-874.
    • (2006) Nat Immunol , vol.7 , pp. 868-874
    • Uematsu, S.1    Jang, M.H.2    Chevrier, N.3
  • 47
    • 33646881322 scopus 로고    scopus 로고
    • Reactivity of naive CD4+CD25-T cells against gut microflora in healthy mice
    • Gad M, Lundsgaard D, Kjellev S, et al. Reactivity of naive CD4+CD25-T cells against gut microflora in healthy mice. Int Immunol. 2006;18:817-825.
    • (2006) Int Immunol , vol.18 , pp. 817-825
    • Gad, M.1    Lundsgaard, D.2    Kjellev, S.3
  • 48
    • 34250026960 scopus 로고    scopus 로고
    • Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
    • Elson CO, Cong Y, Weaver CT, et al. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology. 2007;132:2359-2370.
    • (2007) Gastroenterology , vol.132 , pp. 2359-2370
    • Elson, C.O.1    Cong, Y.2    Weaver, C.T.3
  • 49
    • 58149231532 scopus 로고    scopus 로고
    • Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses
    • Ishigame H, Kakuta S, Nagai T, et al. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity. 2009;30:108-119.
    • (2009) Immunity , vol.30 , pp. 108-119
    • Ishigame, H.1    Kakuta, S.2    Nagai, T.3
  • 50
    • 34249822228 scopus 로고    scopus 로고
    • Expression of interleukin-17F in a mouse model of allergic asthma
    • Suzuki S, Kokubu F, Kawaguchi M, et al. Expression of interleukin-17F in a mouse model of allergic asthma. Int. Arch. Allergy Immunol. 2007; 143(suppl 1):89-94.
    • (2007) Int. Arch. Allergy Immunol , vol.143 , Issue.SUPPL. 1 , pp. 89-94
    • Suzuki, S.1    Kokubu, F.2    Kawaguchi, M.3
  • 51
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC, Tan XY, Luxenberg DP, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med. 2006;203:2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3
  • 52
    • 70249111564 scopus 로고    scopus 로고
    • IL-17A controls IL-17F production and maintains blood neutrophil counts in mice
    • von Veitinghoff S, Ley K. IL-17A controls IL-17F production and maintains blood neutrophil counts in mice. J Immunol. 2009;183:865-873.
    • (2009) J Immunol , vol.183 , pp. 865-873
    • Von Veitinghoff, S.1    Ley, K.2
  • 53
    • 45149109643 scopus 로고    scopus 로고
    • In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells
    • Lochner M, Peduto L, Cherrier M, et al. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J Exp Med. 2008;205:1381-1393.
    • (2008) J Exp Med , vol.205 , pp. 1381-1393
    • Lochner, M.1    Peduto, L.2    Cherrier, M.3
  • 54
    • 77949890873 scopus 로고    scopus 로고
    • IL-6 promotes NK cell production of IL-17 during toxoplasmosis
    • Passos ST, Silver JS, O'Hara AC, et al. IL-6 promotes NK cell production of IL-17 during toxoplasmosis. J Immunol. 2010;184:1776-1783.
    • (2010) J Immunol , vol.184 , pp. 1776-1783
    • Passos, S.T.1    Silver, J.S.2    O'Hara, A.C.3
  • 55
    • 58149384437 scopus 로고    scopus 로고
    • Critical role of RORgammat in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation
    • Michel ML, Mendes-da-Cruz D, Keller AC, et al. Critical role of RORgammat in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation. Proc Natl Acad Sci U S A. 2008;105:19845-19850.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19845-19850
    • Michel, M.L.1    Mendes-Da-Cruz, D.2    Keller, A.C.3
  • 56
    • 49249112420 scopus 로고    scopus 로고
    • IL-17 produced by Paneth cells drives TNF-induced shock
    • Takahashi N, Vanlaere I, de Rycke R, et al. IL-17 produced by Paneth cells drives TNF-induced shock. J Exp Med. 2008;205:1755-1761.
    • (2008) J Exp Med , vol.205 , pp. 1755-1761
    • Takahashi, N.1    Vanlaere, I.2    De Rycke, R.3
  • 57
    • 74949108768 scopus 로고    scopus 로고
    • IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemiareperfusion injury
    • Li L, Huang L, Vergis Al, et al. IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemiareperfusion injury. J Clin Invest. 2010;120:331-342.
    • (2010) J Clin Invest , vol.120 , pp. 331-342
    • Li, L.1    Huang, L.2    Vergis, A.3
  • 58
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • Fujino S, Andoh A, Bamba S, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 2003;52:65-70.
    • (2003) Gut , vol.52 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3
  • 59
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • Buonocore S, Ahern PP, Uhlig HH, et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature. 2010;464:1371-1375.
    • (2010) Nature , vol.464 , pp. 1371-1375
    • Buonocore, S.1    Ahern, P.P.2    Uhlig, H.H.3
  • 60
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • Uhlig HH, McKenzie BS, Hue S, et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity. 2006;25: 309-318.
    • (2006) Immunity , vol.25 , pp. 309-318
    • Uhlig, H.H.1    McKenzie, B.S.2    Hue, S.3
  • 61
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Hueber W, Patel DD, Dryja T, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010;2:52ra72.
    • (2010) Sci Transl Med , vol.2
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.