ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis

European Journal of Immunology

Volumn 43, Issue 7, 2013, Pages 1716-1726

  Liu, Houpu ^a   Yao, Suxia ^a   Dann, Sara M ^a   Qin, Hongwei ^b   Elson, Charles O ^c   Cong, Yingzi ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

Colitis; ERK; Th17; Treg

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; L SELECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH17 CELL; UPREGULATION;

COLITIS; ERK; TH17; TREG;

ANIMALS; CELL DIFFERENTIATION; COLITIS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TRANSFECTION;

EID: 84880028487     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242889     Document Type: Article

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