The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus

Rheumatology

Volumn 48, Issue 12, 2009, Pages 1491-1497

  Kwan, Bonnie Ching Ha ^a   Tam, Lai Shan ^a   Lai, Ka Bik ^a   Lai, Fernand Mac Moune ^a   Li, Edmund Kwok Ming ^a   Wang, Gang ^a   Chow, Kai Ming ^a   Li, Philip Kam Tao ^a   Szeto, Cheuk Chun ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cytokine; Lupus nephritis; SLE

Indexed keywords

CORTICOSTEROID; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 27; MESSENGER RNA; MYCOPHENOLIC ACID; RETINOIC ACID RECEPTOR GAMMA; TRANSCRIPTION FACTOR T BET;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPATHOGENESIS; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL; TH17 CELL; UPREGULATION; URINE SEDIMENT;

ADULT; CYTOKINES; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MALE; MIDDLE AGED; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; T-LYMPHOCYTES, HELPER-INDUCER; TH1 CELLS; TH2 CELLS;

EID: 75649142843     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kep255     Document Type: Article

References (30)

1. Dean GS, Tyrrel-Price J, Crawley E, Isenberg DA. Cytokines and systemic lupus erythematosus. Ann Rheum Dis 2000;59:243-51.
2. Kotzin BL. Systemic lupus erythematosus. Cell 1996;85:303-6.
3. Foster MH, Kelley VR. Lupus nephritis: update on pathogenesis and disease mechanisms. Semin Nephrol 1999;19:173-81.
4. Chan RW, Lai FM, Li EK et al. Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis. Rheumatology 2006;45:951-7.
5. Chan RW, Lai FM, Li EK et al. Expression of T-bet, a type 1 T-helper cell transcription factor, in the urinary sediment of lupus patients predicts disease flare. Rheumatology 2007;46:44-8.
6. Wong CK, Ho CY, Li EK, Lam CW. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 2000;9:589-93.
7. Horwitz DA, Gray JD, Behrendsen SC et al. Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum 1998;41:838-44.
8. Takahashi S, Fossati L, Iwamoto M et al. Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. J Clin Invest 1996;97:1597-604.
9. Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci USA 2002;99:5545-50.
10. Akahoshi M, Nakashima H, Tanaka Y et al. Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum 1999;42:1644-8.
11. Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 2007;13:139-45.
12. Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201: 233-40.
13. Park H, Li Z, Yang XO et al. A distinct lineage of CD4T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005;6:1133-41.
14. Hochberg M. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997;40: 1725-34.
15. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. Arthritis Rheum 1992;35:630-40.
16. Hernandez-Cruz B, Tapia N, Villa-Romero AR, Reyes E, Cardiel MH. Risk factors associated with mortality in systemic lupus erythematosus. A case-control study in a tertiary care center in Mexico City. Clin Exp Rheumatol 2001;19:395-401.
17. Schiffenbauer J, Simon LS. Randomized controlled trials in systemic lupus erythematosus: what has been done and what do we need to do? Lupus 2004;13: 398-405.
18. Chan RW, Chow KM, Tam LS et al. Can urine dipstick test reduce the need of microscopy for the assessment of systemic lupus erythematosus disease activity? J Rheumatol 2005;32:828-31.
19. Li B, Hartono C, Ding R et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 2001;344:947-54.
20. Weening JJ, D'Agati VD, Schwartz MM et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. Kidney Int 2004;65:521-30.
21. Grande JP, Balow JE. Renal biopsy in lupus nephritis. Lupus 1998;7:611-17.
22. Chan TM, Li FK, Tang CS et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong-Guangzhou Nephrology Study Group. N Engl J Med 2000;343:1156-62.
23. Dong G, Ye R, Shi W et al. IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients. Chin Med J 2003;116:543-8.
24. Wong CK, Lit LC, Tam LS, Li EK, Wong PT, Lam CW. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol 2008;127:385-93.
25. Crispi'n JC, Oukka M, Bayliss G et al. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 2008;181:8761-6.
26. Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 Cells. Annu Rev Immunol 2009;27:485-517.
27. Lohr J, Knoechel B, Wang JJ, Villarino AV, Abbas AK. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med 2006;203:2785-91.
28. Koenen HJ, Smeets RL, Vink PM, van Rijssen E, Boots AM, Joosten I. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008;112:2340-52.
29. Beriou G, Costantino CM, Ashley CW et al. IL-17 producing human peripheral regulatory T cells retain suppressive function. Blood 2009;113:4240-9.
30. Chan RW, Lai FM, Li EK et al. Urinary mononuclear cell and disease activity of systemic lupus erythematosus. Lupus 2006;15:262-7.